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13 p, 1.8 MB Detrimental effects of testosterone addition to estrogen therapy involve cytochrome P-450-induced 20-HETE synthesis in aorta of ovariectomized spontaneously hypertensive rat (SHR), a model of postmenopausal hypertension / Costa, Tiago J. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Ceravolo, G. S. (Department of Physiological Sciences. State University of Londrina) ; Echem, Cinthya (Department of Pharmacology. Institute of Biomedical Sciences. University of São Paulo) ; Hashimoto, C. M. (Department of Pharmacology. Institute of Biomedical Sciences. University of São Paulo) ; Costa, B. P. (Department of Pharmacology. Institute of Biomedical Sciences. University of São Paulo) ; Santos-Eichler, R. A. (Department of Pharmacology. Institute of Biomedical Sciences. University of São Paulo) ; Oliveira, M. A. (Department of Pharmacology. Institute of Biomedical Sciences. University of São Paulo) ; Jiménez Altayó, Francesc (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Akamine, Eliana Hiromi (Department of Pharmacology. Institute of Biomedical Sciences. University of São Paulo) ; Dantas, A. P. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Carvalho, M. H. C. (Department of Pharmacology. Institute of Biomedical Sciences. University of São Paulo)
Postmenopausal period has been associated to different symptoms such as hot flashes, vulvovaginal atrophy, hypoactive sexual desire disorder (HSDD) and others. Clinical studies have described postmenopausal women presenting HSDD can benefit from the association of testosterone to conventional hormonal therapy. [...]
2018 - 10.3389/fphys.2018.00490
Frontiers in physiology, Vol. 9 Núm. MAY (august 2018) , p. 490  
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