Artículos publicados

Artículos publicados Encontrados 43 registros  La búsqueda tardó 0.01 segundos. 
1.
5 p, 1.1 MB Screening for epistatic selection signatures : a simulation study / Id-Lahoucine, S. (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Molina, A. (Universidad de Córdoba. Departamento de Genética) ; Cánovas, Angela (University of Guelph. Centre for Genetic Improvement of Livestock. Department of Animal Biosciences) ; Casellas Vidal, Joaquim (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Detecting combinations of alleles that diverged between subpopulations via selection signature statistics can contribute to decipher the phenomenon of epistasis. This research focused on the simulation of genomic data from subpopulations under divergent epistatic selection (ES). [...]
2019 - 10.1038/s41598-019-38689-2
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 1026  
2.
15 p, 1.9 MB Cigarette smoke exposure redirects Staphylococcus aureus to a virulence profile associated with persistent infection / Lacoma, Alicia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Edwards, A.M. (MRC Centre for Molecular Bacteriology and Infection. Imperial College London) ; Young, Bernadette (Nuffield Department of Medicine. Experimental Medicine Division. University of Oxford) ; Domínguez, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Prat i Aymerich, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Laabei, Maisem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Tobacco smoking represents the leading preventable cause of death worldwide. Smoking is a recognised risk factor for several pathologies and is detrimental to host immune surveillance and defence. However, the impact of smoking on microbial residents of the nasopharyngeal cavity, in contact with cigarette smoke (CS), is lacking. [...]
2019 - 10.1038/s41598-019-47258-6
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 10798  
3.
10 p, 1.3 MB Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia / Bonham, L.W. (Neuroradiology Section. Department of Radiology and Biomedical Imaging. University of California. San Francisco) ; Steele, N.Z.R. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; Karch, C.M. (Department of Psychiatry. Washington University) ; Broce, I. (Neuroradiology Section. Department of Radiology and Biomedical Imaging. University of California. San Francisco) ; Geier, E.G. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; Wen, N.L. (Department of Psychiatry. Washington University) ; Momeni, P. (Texas Tech University Health Science Center. Laboratory of Neurogenetics) ; Hardy, J. (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ; Miller, Z.A. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; Gorno-Tempini, M.L. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; Hess, C.P. (Neuroradiology Section. Department of Radiology and Biomedical Imaging. University of California. San Francisco) ; Lewis, P. (School of Pharmacy. University of Reading. Whiteknights) ; Miller, B.L. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; Seeley, W.W. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; Manzoni, C. (School of Pharmacy. University of Reading. Whiteknights) ; Desikan, R.S. (Neuroradiology Section. Department of Radiology and Biomedical Imaging. University of California. San Francisco) ; Baranzini, S.E. (Department of Neurology. University of California. San Francisco) ; Ferrari, R. (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ; Yokoyama, J.S. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; Hernandez, D.G. (UCL Institute of Neurology (Regne Unit)) ; Nalls, M.A. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ; Rohrer, J.D. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Ramasamy, A. (The Jenner Institute. University of Oxford) ; Kwok, J.B.J. (School of Medical Sciences. University of New South Wales) ; Dobson-Stone, C. (School of Medical Sciences. University of New South Wales) ; Schofield, P.R. (School of Medical Sciences. University of New South Wales) ; Halliday, G.M. (School of Medical Sciences. University of New South Wales) ; Hodges, J.R. (School of Medical Sciences. University of New South Wales) ; Piguet, O. (School of Medical Sciences. University of New South Wales) ; Bartley, L. (School of Medical Sciences. University of New South Wales) ; Thompson, E. (Department of Paediatrics. University of Adelaide) ; Haan, E. (Department of Paediatrics. University of Adelaide) ; Hernández, Isabel (Institut Català de Neurociènces Aplicades) ; Ruiz, A. (Institut Català de Neurociènces Aplicades) ; Boada, M. (Institut Català de Neurociènces Aplicades) ; Borroni, B. (Neurology Clinic. University of Brescia) ; Padovani, A. (Neurology Clinic. University of Brescia) ; Cruchaga, Carlos (Hope Center. Washington University School of Medicine) ; Cairns, N.J. (Department of Pathology and Immunology. Washington University) ; Benussi, Luisa (Molecular Markers Laboratory. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Binetti, G. (MAC Memory Clinic. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Ghidoni, R. (Molecular Markers Laboratory. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Forloni, G. (Biology of Neurodegenerative Disorders. IRCCS Istituto di Ricerche Farmacologiche "Mario Negri") ; Albani, Diego (Biology of Neurodegenerative Disorders. IRCCS Istituto di Ricerche Farmacologiche "Mario Negri") ; Galimberti, D. (Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ; Fenoglio, C. (Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ; Serpente, M. (Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ; Scarpini, E. (Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ; Clarimón, J. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Lleó, Alberto (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Blesa, R. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Landqvist Waldö, M. (Unit of Geriatric Psychiatry. Department of Clinical Sciences. Lund University) ; Nilsson, K. (Unit of Geriatric Psychiatry. Department of Clinical Sciences. Lund University) ; Nilsson, C. (Clinical Memory Research Unit. Department of Clinical Sciences. Lund University) ; Mackenzie, I.R.A. (Department of Pathology and Laboratory Medicine. University of British Columbia) ; Hsiung, G.Y.R. (Division of Neurology. University of British Columbia) ; Mann, D.M.A. (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ; Grafman, J. (Department of Psychology. Weinberg College of Arts and Sciences. Northwestern University) ; Morris, C.M. (Institute of Neuroscience. Newcastle University Medical School) ; Attems, J. (Institute of Neuroscience and Institute for Ageing. Campus for Ageing and Vitality. Newcastle University) ; Griffiths, T.D. (Institute of Neuroscience. Newcastle University Medical School) ; McKeith, I.G. (Institute of Neuroscience and Institute for Ageing. Campus for Ageing and Vitality. Newcastle University) ; Thomas, A.J. (Institute of Neuroscience and Institute for Ageing. Campus for Ageing and Vitality. Newcastle University) ; Pietrini, P. (IMT School for Advanced Studies. Lucca) ; Huey, E.D. (Taub Institute. Departments of Psychiatry and Neurology. Columbia University) ; Wassermann, E.M. (Behavioral Neurology Unit. National Insititute of Neurological Disorders and Stroke. National Insititutes of Health) ; Baborie, A. (Department of Laboratory Medicine & Pathology. University of Alberta Edmonton) ; Jaros, E. (Institute of Neuroscience and Institute for Ageing. Campus for Ageing and Vitality. Newcastle University) ; Tierney, M.C. (Behavioral Neurology Unit. National Insititute of Neurological Disorders and Stroke. National Insititutes of Health) ; Pastor, Pau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Razquin, C. (Neurogenetics Laboratory. Division of Neurosciences. Center for Applied Medical Research. Universidad de Navarra) ; Ortega-Cubero, S. (Neurogenetics Laboratory. Division of Neurosciences. Center for Applied Medical Research. Universidad de Navarra) ; Alonso, E. (Department of Neurology. Clínica Universidad de Navarra. University of Navarra School of Medicine) ; Perneczky, Robert (Department of Psychiatry and Psychotherapy. Technische Universität München) ; Diehl-Schmid, J. (Department of Psychiatry and Psychotherapy. Technische Universität München) ; Alexopoulos, P. (Department of Psychiatry and Psychotherapy. Technische Universität München) ; Kurz, A. (Department of Psychiatry and Psychotherapy. Technische Universität München) ; Rainero, I. (Neurology I. Department of Neuroscience. University of Torino. Italy. A.O. Città della Salute e della Scienza di Torino) ; Rubino, E. (Neurology I. Department of Neuroscience. University of Torino. Italy. A.O. Città della Salute e della Scienza di Torino) ; Pinessi, L. (Neurology I. Department of Neuroscience. University of Torino. Italy. A.O. Città della Salute e della Scienza di Torino) ; Rogaeva, E. (Tanz Centre for Research in Neurodegenerative Diseases. University of Toronto) ; St George-Hyslop, P. (Cambridge Institute for Medical Research. and the Department of Clinical Neurosciences. University of Cambridge) ; Rossi, G. (Division of Neurology and Neuropathology. Fondazione IRCCS Istituto Neurologico Carlo Besta) ; Tagliavini, F. (Division of Neurology and Neuropathology. Fondazione IRCCS Istituto Neurologico Carlo Besta) ; Giaccone, G. (Division of Neurology and Neuropathology. Fondazione IRCCS Istituto Neurologico Carlo Besta) ; Rowe, J.B. (Behavioural and Clinical Neuroscience Institute) ; Schlachetzki, J.C.M. (University of California San Diego. Department of Cellular & Molecular Medicine) ; Uphill, J. (UCL Institute of Neurology (Regne Unit). Department of Neurodegenerative Disease) ; Collinge, J. (UCL Institute of Neurology (Regne Unit). Department of Neurodegenerative Disease) ; Mead, S. (UCL Institute of Neurology (Regne Unit). Department of Neurodegenerative Disease) ; Danek, A. (Ludwig-Maximilians-Universität München) ; Van Deerlin, V.M. (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; Grossman, M. (Department of Neurology and Penn Frontotemporal Degeneration Center. University of Pennsylvania Perelman School of Medicine) ; Trojanowski, J.Q. (Laboratory of Neurogenetics. Institute Born-Bunge. University of Antwerp) ; van der Zee, J. (Laboratory of Neurogenetics. Institute Born-Bunge. University of Antwerp) ; Cruts, M. (Laboratory of Neurogenetics. Institute Born-Bunge. University of Antwerp) ; Van Broeckhoven, C. (Laboratory of Neurogenetics. Institute Born-Bunge. University of Antwerp) ; Cappa, S.F. (Neurorehabilitation Unit. Department of Clinical Neuroscience. Vita-Salute University and San Raffaele Scientific Institute) ; Leber, I. (CNRS UMR 7225. F-75013) ; Hannequin, D. (Service de Neurologie. Inserm U1079. CNR-MAJ. Rouen University Hospital) ; Golfier, V. (Service de Neurologie. CH Saint Brieuc) ; Vercelletto, M. (Service de neurologie. CHU de Nantes) ; Brice, A. (CNRS UMR 7225. F-75013) ; Nacmias, B. (Department of Neurosciences. Psychology. Drug Research and Child Health (NEUROFARBA) University of Florence) ; Sorbi, Sandro (Department of Neurosciences. Psychology. Drug Research and Child Health (NEUROFARBA) University of Florence) ; Bagnoli, Silvia (Department of Neurosciences. Psychology. Drug Research and Child Health (NEUROFARBA) University of Florence) ; Piaceri, I. (Department of Neurosciences. Psychology. Drug Research and Child Health (NEUROFARBA) University of Florence) ; Nielsen, J.E. (Department of Cellular and Molecular Medicine. Section of Neurogenetics. The Panum Institute. University of Copenhagen) ; Hjermind, L.E. (Department of Cellular and Molecular Medicine. Section of Neurogenetics. The Panum Institute. University of Copenhagen) ; Riemenschneider, M. (Laboratory for Neurogenetics. Saarland University) ; Mayhaus, M. (Laboratory for Neurogenetics. Saarland University) ; Ibach, B. (Department of Psychiatry. Psychotherapy and Psychosomatics) ; Gasparoni, G. (Laboratory for Neurogenetics. Saarland University) ; Pichler, S. (Laboratory for Neurogenetics. Saarland University) ; Gu, W. (Luxembourg Centre For Systems Biomedicine (LCSB). University of Luxembourg) ; Rossor, M.N. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Fox, N.C. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Warren, J.D. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Spillantini, M.G. (Department of Clinical Neurosciences. John Van Geest Brain Repair Centre. Forvie Site. University of Cambridge) ; Morris, H.R. (UCL Institute of Neurology (Regne Unit). Department of Molecular Neuroscience) ; Rizzu, P. (Tübingen Site. German Center for Neurodegenerative Diseases) ; Heutink, P. (Tübingen Site. German Center for Neurodegenerative Diseases) ; Snowden, J.S. (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ; Rollinson, Sara (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ; Richardson, A. (Salford Royal Foundation Trust. Faculty of Medical and Human Sciences. University of Manchester) ; Gerhard, A. (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ; Bruni, A.C. (Regional Neurogenetic Centre. ASPCZ) ; Maletta, R. (Regional Neurogenetic Centre. ASPCZ) ; Frangipane, F. (Regional Neurogenetic Centre. ASPCZ) ; Cupidi, C. (Regional Neurogenetic Centre. ASPCZ) ; Bernardi, L. (Regional Neurogenetic Centre. ASPCZ) ; Anfossi, M. (Regional Neurogenetic Centre. ASPCZ) ; Gallo, M. (Regional Neurogenetic Centre. ASPCZ) ; Conidi, Maria E (Regional Neurogenetic Centre. ASPCZ) ; Smirne, N. (Regional Neurogenetic Centre. ASPCZ) ; Rademakers, R. (Department of Neuroscience. Mayo Clinic Jacksonville) ; Baker, M. (Department of Neuroscience. Mayo Clinic Jacksonville) ; Dickson, Dennis W. (Department of Neuroscience. Mayo Clinic Jacksonville) ; Graff-Radford, N.R. (Department of Neuroscience. Mayo Clinic Jacksonville) ; Petersen, R.C. (Department of Neurology. Mayo Clinic Rochester) ; Knopman, D. (Department of Neurology. Mayo Clinic Rochester) ; Josephs, K.A. (Department of Neurology. Mayo Clinic Rochester) ; Boeve, B.F. (Department of Neurology. Mayo Clinic Rochester) ; Parisi, J.E. (Department of Pathology. Mayo Clinic Rochester) ; Karydas, A.M. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; Rosen, H. (Memory and Aging Center. Department of Neurology. University of California. San Francisco) ; van Swieten, J.C. (Department of Medical Genetics. VU university Medical Centre) ; Dopper, E.G.P. (Department of Medical Genetics. VU university Medical Centre) ; Seelaar, H. (Department of Medical Genetics. VU university Medical Centre) ; Pijnenburg, Y.A.L. (VU University Medical Centre. Department of Neurology) ; Scheltens, Philip (VU University Medical Centre. Department of Neurology) ; Logroscino, Giancarlo (Department of Basic Medical Sciences. Neurosciences and Sense Organs. "Aldo Moro" University of Bari) ; Capozzo, R. (Department of Basic Medical Sciences. Neurosciences and Sense Organs. "Aldo Moro" University of Bari) ; Novelli, V. (Medical Genetics Unit. Fondazione Policlinico Universitario A. Gemelli) ; Puca, A.A. (Department of Medicine and Surgery. University of Salerno) ; Franceschi, M. (Neurology Department. IRCCS Multimedica) ; Postiglione, A. (Department of Clinical Medicine and Surgery. University of Naples Federico II) ; Milan, G. (Geriatric Center Frullone ASL Napoli 1 Centro) ; Sorrentino, P. (Geriatric Center Frullone ASL Napoli 1 Centro) ; Kristiansen, M. (UCL Genomics. Institute of Child Health (ICH). UCL) ; Chiang, H.H. (Karolinska University Hospital and Karolinska Institutet (Suecia)) ; Graff, C. (Karolinska University Hospital and Karolinska Institutet (Suecia)) ; Pasquier, F. (Université des Sciences et Technologies de Lille. Inserm 1171. DISTALZ. CHU 59000) ; Rollin, A. (Université des Sciences et Technologies de Lille. Inserm 1171. DISTALZ. CHU 59000) ; Deramecourt, V. (Université des Sciences et Technologies de Lille. Inserm 1171. DISTALZ. CHU 59000) ; Lebouvier, T. (Université des Sciences et Technologies de Lille. Inserm 1171. DISTALZ. CHU 59000) ; Kapogiannis, D. (National Institute on Aging (NIA/NIH)) ; Ferrucci, L. (National Institute on Aging (Baltimore, Estats Units d'Amèrica)) ; Pickering-Brown, S. (Institute of Brain. Behaviour and Mental Health. University of Manchester. Salford Royal Hospital) ; Singleton, A.B. (National Institute on Aging (Bethesda, Estats Units d'Amèrica)) ; Universitat Autònoma de Barcelona
The semantic variant of primary progressive aphasia (svPPA) is a clinical syndrome characterized by neurodegeneration and progressive loss of semantic knowledge. Unlike many other forms of frontotemporal lobar degeneration (FTLD), svPPA has a highly consistent underlying pathology composed of TDP-43 (a regulator of RNA and DNA transcription metabolism). [...]
2019 - 10.1038/s41598-019-46415-1
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 10854  
4.
15 p, 4.1 MB Prenatal Betamethasone interferes with immune system development and alters target cells in autoimmune diabetes / Perna-Barrull, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodríguez-Fernández, Silvia (Institut Germans Trias i Pujol) ; Pujol-Autonell, Irma (Institut Germans Trias i Pujol) ; Gieras, A. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ; Ampudia Carrasco, Rosa María (Institut Germans Trias i Pujol) ; Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ; Glau, L. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ; Tolosa, E. (Department of Immunology. University Medical Center Hamburg-Eppendorf) ; Vives Pi, Marta (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Non-genetic factors are crucial in the pathogenesis of type 1 diabetes (T1D), a disease caused by autoimmunity against insulin-producing β-cells. Exposure to medications in the prenatal period may influence the immune system maturation, thus altering self-tolerance. [...]
2019 - 10.1038/s41598-018-37878-9
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 1235  
5.
20 p, 2.6 MB Cerium oxide nanoparticles display antilipogenic effect in rats with non-alcoholic fatty liver disease / Carvajal, Silvia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Perramón, Meritxell (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Oró, Denise (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Casals, Eudald (Wuyi University. School of Biotechnology and Health Sciences) ; Fernández-Varo, Guillermo (Universitat de Barcelona. Departament de Biomedicina) ; Parra-Robert, Marina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; González de la Presa, Bernardino. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ribera, Jordi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Pastor, Óscar (Hospital Universitario Ramón y Cajal (Madrid)) ; Morales Ruiz, Manuel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Jiménez, Wladimiro (Universitat de Barcelona. Departament de Biomedicina)
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide, ranging from steatosis to non-alcoholic steatohepatitis (NASH). Recently, cerium oxide nanoparticles (CeO₂NPs) have emerged as a new antioxidant agent with hepatoprotective properties in experimental liver disease. [...]
2019 - 10.1038/s41598-019-49262-2
Scientific reports (Nature Publishing Group), Vol. 9 (2019) , art. 12848  
6.
11 p, 1.6 MB Infectious phage particles packaging antibiotic resistance genes found in meat products and chicken feces / Gómez-Gómez, Clara (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Blanco-Picazo, Pedro (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Brown-Jaque, Maryury (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Quirós, Pablo (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Rodríguez-Rubio, Lorena (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Cerdà-Cuellar, Marta (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Muniesa, Maite (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística)
Bacteriophages can package part of their host's genetic material, including antibiotic resistance genes (ARGs), contributing to a rapid dissemination of resistances among bacteria. Phage particles containing ARGs were evaluated in meat, pork, beef and chicken minced meat, and ham and mortadella, purchased in local retailer. [...]
2019 - 10.1038/s41598-019-49898-0
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 13281  
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8 p, 953.3 KB Statin use and the risk of colorectal cancer in a population-based electronic health records study / Ibáñez-Sanz, Gemma (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Guinó, Elisabet (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Pontes García, Caridad (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Quijada-Manuitt, M.Ángeles (Institut d'Investigació Biomèdica Sant Pau) ; de la Peña-Negro, Luisa C. (Hospital de Viladecans) ; Aragón, María . (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Domínguez, Marga (Institut Català d'Oncologia) ; Rodríguez-Alonso, Lorena (Institut d'Investigació Biomèdica de Bellvitge) ; Blasco, Alex (Hospital de Sant Joan Despí Moisès Broggi) ; García-Rodríguez, Ana (Hospital de Viladecans) ; Morros, Rosa (Universitat de Barcelona. Departament de Ciències Clíniques) ; Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia
There is extensive debate regarding the protective effect of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) on colorectal cancer (CRC). We aimed to assess the association between CRC risk and exposure to statins using a large cohort with prescription data. [...]
2019 - 10.1038/s41598-019-49877-5
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 13560  
8.
15 p, 3.0 MB Comparative analysis of the fecal microbiota from different species of domesticated and wild suids / Correa-Fiz, Florencia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Blanco-Fuertes, M. (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Navas, María Jesús (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Lacasta, A. (International Livestock Research Institute (ILRI)) ; Bishop, R.P. (Washington State University. Department of Veterinary Microbiology and Pathology) ; Githaka, N. (International Livestock Research Institute (ILRI)) ; Onzere, C. (Washington State University. Department of Veterinary Microbiology and Pathology) ; Le Potier, M.F. (ANSES Laboratory of Ploufragan-Plouzané-Niort. Swine virology and immunology unit) ; Almagro-Delgado, V. (Zoo de Barcelona) ; Martinez, J. (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ; Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Rodriguez, F. (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Most of the microorganisms living in a symbiotic relationship in different animal body sites (microbiota) reside in the gastrointestinal tract (GIT). Several studies have shown that the microbiota is involved in host susceptibilities to pathogens. [...]
2019 - 10.1038/s41598-019-49897-1
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 13616  
9.
15 p, 2.1 MB Rarity of monodominance in hyperdiverse Amazonian forests / Ter Steege, H. (Free University (Àmsterdam, Països Baixos). Systems Ecology) ; Henkel, T.W. (Department of Biological Sciences. Humboldt State University) ; Helal, N. (Biodiversity Dynamics. Naturalis Biodiversity Center) ; Marimon, B.S. (Programa de Pós-Graduação em Ecologia e Conservação. Universidade do Estado de Mato Grosso) ; Marimon-Junior, B.H. (Programa de Pós-Graduação em Ecologia e Conservação. Universidade do Estado de Mato Grosso) ; Huth, A. (Department of Ecological Modelling. Helmholtz Centre for Environmental Research - UFZ) ; Groeneveld, J. (Institute of Forest Growth and Computer Sciences. Technische Universitaet Dresden) ; Sabatier, D. (AMAP. IRD. CIRAD. CNRS. INRA. Université de Montpellier) ; Coelho, L.d.S. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Filho, D.d.A.L. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Salomão, R.P. (Museu Paraense Emílio Goeldi (Brasil)) ; Amaral, Iêda Leão (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Matos, F.D.d.A. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Castilho, C.V. (EMBRAPA - Centro de Pesquisa Agroflorestal de Roraima) ; Phillips, Oliver L (School of Geography. University of Leeds) ; Guevara, J.E. (Keller Science Action Center. The Field Museum) ; Carim, M.d.J.V. (Instituto de Pesquisas Científicas e Tecnológicas do Amapá-IEPA. Departamento de Botânica) ; Cárdenas López, D. (Herbario Amazónico Colombiano. Instituto SINCHI) ; Magnusson, W.E. (Coordenação de Pesquisas em Ecologia. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Wittmann, F. (Max Planck Institute for Chemistry) ; Irume, M.V. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Martins, M.P. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Guimarães, J.R.d.S. (Instituto de Pesquisas Científicas e Tecnológicas do Amapá-IEPA. Departamento de Botânica) ; Molino, J.F. (AMAP. IRD. CIRAD. CNRS. INRA. Université de Montpellier) ; Bánki, O.S. (Naturalis Biodiversity Center) ; Piedade, M.T.F. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Pitman, N.C.A. (Science and Education. The Field Museum) ; Mendoza, A.M. (Jardín Botánico de Missouri) ; Ramos, J.F. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Luize, B.G. (Departamento de Ecologia. Universidade Estadual Paulista - UNESP - Instituto de Biociências - IB) ; Moraes de Leão Novo, E.M. (Instituto Nacional de Pesquisas Espaciais (Brazil)) ; Núñez Vargas, P. (Herbario Vargas. Universidad Nacional de San Antonio Abad del Cusco) ; Silva, T.S.F. (Departamento de Geografia. Universidade Estadual Paulista -UNESP - Instituto de Geociências e Ciências Extas - IGCE. Bela Vista) ; Venticinque, E.M. (Centro de Biociências. Departamento de Ecologia. Universidade Federal do Rio Grande do Norte) ; Manzatto, A.G. (Departamento de Biologia. Universidade Federal de Rondônia) ; Reis, N.F.C. (Programa de Pós- Graduação em Biodiversidade e Biotecnologia PPG- Bionorte. Universidade Federal de Rondônia) ; Terborgh, J. (Centre for Tropical Environmental and Sustainability Science and College of Science and Engineering. James Cook University) ; Casula, K.R. (Programa de Pós- Graduação em Biodiversidade e Biotecnologia PPG- Bionorte. Universidade Federal de Rondônia) ; Honorio Coronado, E.N. (Instituto de Investigaciones de la Amazonia Peruana) ; Montero, J.C. (Instituto Boliviano de Investigacion Forestal) ; Feldpausch, T.R. (Geography. College of Life and Environmental Sciences. University of Exeter) ; Duque, Alvaro (Universidad Nacional de Colombia. Departamento de Ciencias Forestales) ; Costa, F.R.C. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Arboleda, N.C. (Herbario Amazónico Colombiano. Instituto SINCHI) ; Schöngart, J. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Killeen, T.J. (Agteca-Amazonica) ; Vasquez, R. (Jardín Botánico de Missouri) ; Mostacedo, B. (Universidad Autónoma Gabriel René Moreno (Bolívia). Facultad de Ciencias Agrícolas) ; Demarchi, L.O. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Assis, R.L. (Natural History Museum. University of Oslo) ; Baraloto, C. (International Center for Tropical Botany (ICTB) Department of Biological Sciences. Florida International University) ; Engel, Julien (International Center for Tropical Botany (ICTB) Department of Biological Sciences. Florida International University) ; Petronelli, P. (Cirad UMR Ecofog. AgrosParisTech. CNRS. INRA. Univ Guyane) ; Castellanos, H. (Centro de Investigaciones Ecológicas de Guayana. Universidad Nacional Experimental de Guayana) ; de Medeiros, M.B. (Prédio da Botânica e Ecologia. Embrapa Recursos Genéticos e Biotecnologia. Parque Estação Biológica) ; Quaresma, A. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Simon, M.F. (Prédio da Botânica e Ecologia. Embrapa Recursos Genéticos e Biotecnologia. Parque Estação Biológica) ; Andrade, A. (Projeto Dinâmica Biológica de Fragmentos Florestais. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Camargo, J.L. (Projeto Dinâmica Biológica de Fragmentos Florestais. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Laurance, S.G.W. (Centre for Tropical Environmental and Sustainability Science and College of Science and Engineering. James Cook University) ; Laurance, W.F. (Centre for Tropical Environmental and Sustainability Science and College of Science and Engineering. James Cook University) ; Rincón, L.M. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Schietti, Juliana (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Sousa, T.R. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; de Sousa Farias, E. (Programa de Pós-graduação em Biodiversidade e Saúde. Instituto Oswaldo Cruz - IOC/FIOCRUZ. Pav. Arthur Neiva - Térreo) ; Lopes, M.A. (Instituto de Ciências Biológicas. Universidade Federal do Pará) ; Magalhães, J.L.L. (Embrapa Amazônia Oriental) ; Mendonça Nascimento, H.E. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Lima de Queiroz, H. (Instituto de Desenvolvimento Sustentável Mamirauá (Brasil)) ; Aymard C, G.A. (Programa de Ciencias del Agro y el Mar. Herbario Universitario (PORT). UNELLEZ-Guanare) ; Brienen, R. (School of Geography. University of Leeds) ; Revilla, J.D.C. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Vieira, I.C.G. (Museu Paraense Emílio Goeldi (Brasil)) ; Cintra, B.B.L. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Stevenson, P.R. (Laboratorio de Ecología de Bosques Tropicales y Primatología. Universidad de los Andes) ; Feitosa, Yuri Oliveira (Programa de Pós-Graduação em Biologia (Botânica). Instituto Nacional de Pesquisas da Amazônia - INPA) ; Duivenvoorden, J.F. (Institute of Biodiversity and Ecosystem Dynamics. University of Amsterdam) ; Mogollón, H.F. (Endangered Species Coalition) ; Araujo-Murakami, A. (Universidad Autónoma Gabriel René Moreno (Bolívia)) ; Ferreira, L.V. (Museu Paraense Emílio Goeldi (Brasil)) ; Lozada, J.R. (Facultad de Ciencias Forestales y Ambientales. Instituto de Investigaciones para el Desarrollo Forestal. Universidad de los Andes) ; Comiskey, J.A. (Smithsonian Conservation Biology Institute) ; de Toledo, J.J. (Universidade Federal do Amapá. Ciências Ambientais) ; Damasco, G. (Department of Integrative Biology. University of California) ; Dávila, N. (Biologia Vegetal. Universidade Estadual de Campinas) ; Draper, Freddie (Carnegie Institution for Science (Washington, Estats Units d'Amèrica). Department of Global Ecology) ; García-Villacorta, Roosevelt (Tropical Diversity Section. Royal Botanic Garden Edinburgh) ; Lopes, A. (Department of Ecology. University of Brasilia) ; Vicentini, A. (Coordenação de Pesquisas em Ecologia. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Alonso, A. (Smithsonian Conservation Biology Institute) ; Dallmeier, F. (Smithsonian Conservation Biology Institute) ; Gomes, V.H.F. (Programa de Pós-Graduação em Ciência Ambientais. Universidade Federal do Pará) ; Lloyd, J. (Imperial College London. Department of Life Sciences) ; Neill, D. (Ecosistemas. Biodiversidad y Conservación de Especies. Universidad Estatal Amazónica) ; de Aguiar, D.P.P. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Arroyo, L. (Universidad Autónoma Gabriel René Moreno (Bolívia)) ; Carvalho, F.A. (Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Genética. Ecologia e Evolução) ; de Souza, F.C. (Coordenação de Pesquisas em Ecologia. Instituto Nacional de Pesquisas da Amazônia - INPA) ; do Amaral, D.D. (Museu Paraense Emílio Goeldi (Brasil)) ; Feeley, K.J. (Fairchild Tropical Botanic Garden) ; Gribel, R. (Diretoria de Pesquisas Científicas. Instituto de Pesquisas Jardim Botânico do Rio de Janeiro) ; Pansonato, M.P. (Instituto de Biociências - Dept. Ecologia. Universidade de Sao Paulo - USP. Rua do Matão) ; Barlow, J. (Lancaster Environment Centre. Lancaster University) ; Berenguer, E. (Environmental Change Institute. University of Oxford) ; Ferreira, J. (Embrapa Amazônia Oriental) ; Fine, P.V.A. (Department of Integrative Biology. University of California) ; Guedes, M.C. (Empresa Brasileira de Pesquisa Agropecuária. Embrapa Amapá) ; Jimenez, E.M. (Grupo de Investigación en Tecnologías de la Información y Medio Ambiente. Instituto Tecnológico de Antioquia - Institución Universitaria) ; Licona, J.C. (Instituto Boliviano de Investigacion Forestal) ; Peñuela Mora, M.C. (Universidad Regional Amazónica IKIAM) ; Villa, B. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Cerón, C. (Escuela de Biología Herbario Alfredo Paredes. Universidad Central) ; Maas, P. (Taxonomy and Systematics. Naturalis Biodiversity Center) ; Silveira, M. (Universidade Federal do Acre. Centro de Ciências Biológicas e da Natureza) ; Stropp, J. (Institute of Biological and Health Sciences. Federal University of Alagoas) ; Thomas, Raquel (Iwokrama International Centre for Rainforest Conservation) ; Baker, T.R. (School of Geography. University of Leeds) ; Daly, D. (New York Botanical Garden) ; Dexter, K.G. (School of Geosciences. University of Edinburgh) ; Huamantupa-Chuquimaco, I. (Herbario Vargas. Universidad Nacional de San Antonio Abad del Cusco) ; Milliken, W. (Natural Capital and Plant Health. Royal Botanic Gardens. Kew) ; Pennington, T. (Tropical Diversity Section. Royal Botanic Garden Edinburgh) ; Ríos Paredes, M. (Servicios de Biodiversidad EIRL) ; Fuentes, A. (Center for Conservation and Sustainable Development. Missouri Botanical Garden) ; Klitgaard, B. (Department for Identification & Naming. Royal Botanic Gardens. Kew) ; Pena, J.L.M. (Department of Forestry Management. Universidad Nacional Agraria La Molina) ; Peres, C.A. (School of Environmental Sciences. University of East Anglia) ; Silman, Miles R (Biology Department and Center for Energy. Environment and Sustainability. Wake Forest University) ; Tello, J.S. (Center for Conservation and Sustainable Development. Missouri Botanical Garden) ; Chave, J. (Laboratoire Evolution et Diversité Biologique. CNRS and Université Paul Sabatier. UMR 5174 EDB) ; Cornejo Valverde, Fernando (Andes to Amazon Biodiversity Program) ; Di Fiore, Anthony (Department of Anthropology. University of Texas at Austin) ; Hilário, R.R. (Universidade Federal do Amapá. Ciências Ambientais) ; Phillips, J.F. (Fundación Puerto Rastrojo) ; Rivas-Torres, G. (Department of Wildlife Ecology and Conservation. University of Florida) ; Van Daalen, Tal R (Biodiversity Dynamics. Naturalis Biodiversity Center) ; von Hildebrand, P. (Fundación Estación de Biología) ; Noronha, J.C. (ICNHS. Federal University of Mato Grosso) ; Barbosa, E.M (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Barbosa, F.R. (ICNHS. Federal University of Mato Grosso) ; de Matos Bonates, L.C. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Carpanedo, R.d.S. (ICNHS. Federal University of Mato Grosso) ; Dávila Doza, H.P. (Servicios de Biodiversidad EIRL) ; Fonty, Émile (Direction régionale de la Guyane. ONF) ; GómeZárate z, R. (PROTERRA. Instituto de Investigaciones de la Amazonía Peruana (IIAP)) ; Gonzales, T. (ACEER Foundation) ; Gallardo Gonzales, G.P. (Servicios de Biodiversidad EIRL) ; Hoffman, B. (Amazon Conservation Team) ; Junqueira, André Braga (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ; Malhi, Y. (Environmental Change Institute. Oxford University Centre for the Environment. Dyson Perrins Building) ; Miranda, I.P.d.A. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Pinto, L.F.M. (Servicios de Biodiversidad EIRL) ; Prieto, A. (Instituto de Ciencias Naturales. Universidad Nacional de Colombia) ; Rodrigues, D.d.J. (ICNHS. Federal University of Mato Grosso) ; Rudas, A. (Instituto de Ciencias Naturales. Universidad Nacional de Colombia) ; Ruschel, A.R. (Embrapa Amazônia Oriental) ; Silva, N. (Instituto de Ciência Agrárias. Universidade Federal Rural da Amazônia) ; Vela, C.I.A. (Escuela Profesional de Ingeniería Forestal. Universidad Nacional de San Antonio Abad del Cusco) ; Vos, V.A. (Universidad Autónoma del Beni José Ballivián) ; Zent, E.L. (Laboratory of Human Ecology. Instituto Venezolano de Investigaciones Científicas - IVIC) ; Zent, Stanford (Laboratory of Human Ecology. Instituto Venezolano de Investigaciones Científicas - IVIC) ; Weiss Albuquerque, B. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Cano, A. (Cambridge University Botanic Garden. 1 Brookside.) ; Carrero Márquez, Y.A. (Facultad de Ciencias Forestales y Ambientales. Instituto de Investigaciones para el Desarrollo Forestal. Universidad de los Andes) ; Correa, Diego F (University of Queensland. School of Agriculture and Food Sciences) ; Costa, J.B.P. (Empresa Brasileira de Pesquisa Agropecuária. Embrapa Amapá) ; Flores, B.M. (University of Campinas. Plant Biology Department) ; Galbraith, D. (School of Geography. University of Leeds) ; Holmgren, Milena (Resource Ecology Group. Wageningen University & Research) ; Kalamandeen, M. (School of Geography. University of Leeds) ; Nascimento, M.T. (Laboratório de Ciências Ambientais. Universidade Estadual do Norte Fluminense) ; Oliveira, A.A. (Instituto de Biociências - Dept. Ecologia. Universidade de Sao Paulo - USP. Rua do Matão) ; Ramirez-Angulo, H. (Instituto de Investigaciones para el Desarrollo Forestal (INDEFOR). Universidad de los Andes. Conjunto Forestal) ; Rocha, M. (Coordenação de Dinâmica Ambiental. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Scudeller, V.V. (Departamento de Biologia. Universidade Federal do Amazonas - UFAM - Instituto de Ciências Biológicas - ICB1) ; Sierra, R. (GeoIS. El Día 369y El Telégrafo. 3° Piso) ; Tirado, M. (GeoIS. El Día 369y El Telégrafo. 3° Piso) ; Umaña Medina, M.N. (Department of Biology. University of Maryland) ; van der Heijden, G. (University of Nottingham. University Park) ; Vilanova Torre, E. (School of Environmental and Forest Sciences. University of Washington) ; Vriesendorp, C. (Science and Education. The Field Museum) ; Wang, O. (Environmental Science and Policy. Northern Arizona University) ; Young, Kenneth R (Geography and the Environment. University of Texas at Austin) ; Ahuite Reategui, M.A. (Medio Ambiente. PLUSPRETOL) ; Baider, C. (The Mauritius Herbarium. Agricultural Services. Ministry of Agro-Industry and Food Security) ; Balslev, H. (Department of Bioscience. Aarhus University) ; Cárdenas, S. (Laboratorio de Ecología de Bosques Tropicales y Primatología. Universidad de los Andes) ; Casas, L.F. (Laboratorio de Ecología de Bosques Tropicales y Primatología. Universidad de los Andes) ; Farfan-Rios, W. (Biology Department and Center for Energy. Environment and Sustainability. Wake Forest University) ; Ferreira, C. (Coordenação de Biodiversidade. Instituto Nacional de Pesquisas da Amazônia - INPA) ; Linares-Palomino, R. (Smithsonian Conservation Biology Institute) ; Mendoza, C. (Escuela de Ciencias Forestales (ESFOR). Universidad Mayor de San Simon (UMSS)) ; Mesones, I. (Department of Integrative Biology. University of California) ; Torres-Lezama, A. (Instituto de Investigaciones para el Desarrollo Forestal (INDEFOR). Universidad de los Andes. Conjunto Forestal) ; Giraldo, L.E.U. (Departamento de Ciencias Forestales. Universidad Nacional de Colombia) ; Villarroel, D. (Universidad Autónoma Gabriel René Moreno (Bolívia)) ; Zagt, R. (Tropenbos International) ; Alexiades, M.N. (School of Anthropology and Conservation. University of Kent) ; de Oliveira, E.A. (Programa de Pós-Graduação em Ecologia e Conservação. Universidade do Estado de Mato Grosso) ; Garcia-Cabrera, K. (Biology Department and Center for Energy. Environment and Sustainability. Wake Forest University) ; Hernández, Lionel (Centro de Investigaciones Ecológicas de Guayana. Universidad Nacional Experimental de Guayana) ; Palacios Cuenca, W. (Herbario Nacional del Ecuador. Universidad Técnica del Norte) ; Pansini, S. (Programa de Pós- Graduação em Biodiversidade e Biotecnologia PPG- Bionorte. Universidade Federal de Rondônia) ; Pauletto, D. (Instituto de Biodiversidade e Floresta. Universidade Federal do Oeste do Pará) ; Ramirez Arevalo, F. (Facultad de Biologia. Universidad Nacional de la Amazonia Peruana) ; Sampaio, A.F. (Programa de Pós- Graduação em Biodiversidade e Biotecnologia PPG- Bionorte. Universidade Federal de Rondônia) ; Sandoval, E.H.V. (Department of Biology. University of Missouri) ; Valenzuela Gamarra, L. (Jardín Botánico de Missouri) ; Levesley, A. (School of Geography. University of Leeds) ; Pickavance, G. (School of Geography. University of Leeds) ; Melgaço, K. (School of Geography. University of Leeds)
Tropical forests are known for their high diversity. Yet, forest patches do occur in the tropics where a single tree species is dominant. Such "monodominant" forests are known from all of the main tropical regions. [...]
2019 - 10.1038/s41598-019-50323-9
Scientific reports (Nature Publishing Group), Vol. 9 (2019) , art. 13822  
10.
8 p, 1.3 MB Morphological changes of the pancreas after pancreaticoduodenectomy / Quesada, R. (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Simón, C. (Universitat Autònoma de Barcelona) ; Radosevic, A. (Hospital del Mar (Barcelona, Catalunya)) ; Poves, I. (Hospital del Mar (Barcelona, Catalunya)) ; Grande, L. (Hospital del Mar (Barcelona, Catalunya)) ; Burdío, Fernando (Hospital del Mar (Barcelona, Catalunya))
The aim of this retrospective study was thus to evaluate postoperative morphological changes in the remnant pancreas after pancreaticoduodenectomy (PD) associated with postoperative pancreatic fistula (POPF). [...]
2019 - 10.1038/s41598-019-51173-1
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 14517  
11.
9 p, 1.7 MB EV-associated miRNAs from pleural lavage as potential diagnostic biomarkers in lung cancer / Roman-Canal, Berta (Hospital Universitari de Bellvitge) ; Moiola, Cristian Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gatius, Sònia (Institut de Recerca Biomèdica de Lleida) ; Bonnin, Sarah (Centre for Genomic Regulation (CRG). The Barcelona Institute or Science and Technology) ; Ruiz-Miró, María (Institut de Recerca Biomèdica de Lleida) ; González, Esperanza (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Ojanguren, Amaia (Institut de Recerca Biomèdica de Lleida) ; Recuero, José Luis (Institut de Recerca Biomèdica de Lleida) ; Gil-Moreno, Antonio (Hospital Universitari Vall d'Hebron) ; Falcón-Pérez, Juan M (IKERBASQUE. Basque Foundation for Science) ; Ponomarenko, Julia (Centre for Genomic Regulation (CRG). The Barcelona Institute or Science and Technology) ; Porcel, José M. (Institut de Recerca Biomèdica de Lleida) ; Matias-Guiu, Xavier (Hospital Universitari de Bellvitge) ; Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Lung cancer is the leading cause of cancer-related deaths among men and women in the world, accounting for the 25% of cancer mortality. Early diagnosis is an unmet clinical issue. In this work, we focused to develop a novel approach to identify highly sensitive and specific biomarkers by investigating the use of extracellular vesicles (EVs) isolated from the pleural lavage, a proximal fluid in lung cancer patients, as a source of potential biomarkers. [...]
2019 - 10.1038/s41598-019-51578-y
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 15057  
12.
14 p, 12.2 MB Unique skull network complexity of Tyrannosaurus rex among land vertebrates / Werneburg, Ingmar (Museum für Naturkunde) ; Esteve-Altava, Borja (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Araújo Bruno, Joana (Universitat Autònoma de Barcelona. Departament de Prehistòria) ; Torres Ladeira, Marta (Paläontologisches Institut und Museum der Universität Zürich) ; Diogo, Rui (Howard University College of Medicine. Department of Anatomy)
Like other diapsids, Tyrannosaurus rex has two openings in the temporal skull region. In addition, like in other dinosaurs, its snout and lower jaw show large cranial fenestrae. In T. rex, they are thought to decrease skull weight, because, unlike most other amniotes, the skull proportion is immense compared to the body. [...]
2019 - 10.1038/s41598-018-37976-8
Scientific reports (Nature Publishing Group), Vol. 9 (january 2019) , p. e1520  
13.
14 p, 1.8 MB Effects of attachment-based compassion therapy (ABCT) on brain-derived neurotrophic factor and low-grade inflammation among fibromyalgia patients : a randomized controlled trial / Montero-Marín, Jesús (RedIAPP (Red de Investigación en Actividades Preventivas y Promoción de la Salud)) ; Andrés-Rodríguez, Laura (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ; Tops, Mattie (Vrije Universiteit) ; Luciano, Juan V. (Parc Sanitari Sant Joan de Déu) ; Navarro-Gil, Mayte (Universidad de Zaragoza. Departamento de Psicología i Sociología) ; Feliu-Soler, Albert (Parc Sanitari Sant Joan de Déu) ; López-del-Hoyo, Yolanda (Universidad de Zaragoza. Departamento de Psicología y Sociología) ; Garcia-Campayo, Javier (Hospital Universitario Miguel Servet (Saragossa))
Fibromyalgia (FM) is a disabling syndrome characterized by chronic pain associated with fatigue. Its pathogenesis is unknown, but alterations in central sensitization, involving an imbalance of brain-derived neurotrophic factor (BDNF) and inflammatory biomarkers, appear to be implicated. [...]
2019 - 10.1038/s41598-019-52260-z
Scientific reports (Nature Publishing Group), Vol. 9, núm. 1 (january 2019) , p. 15639  
14.
10 p, 1.7 MB IL-7/IL-7R gene variants impact circulating IL-7/IL-7R homeostasis and ART-associated immune recovery status / Ceausu, A. (Hospital Universitari Joan XXIII de Tarragona) ; Rodríguez-Gallego, E. (Hospital Universitari Joan XXIII de Tarragona) ; Peraire, J. (Hospital Universitari Joan XXIII de Tarragona) ; López-Dupla, M. (Hospital Universitari Joan XXIII de Tarragona) ; Domingo, P. (Institut d'Investigació Biomèdica Sant Pau) ; Viladés, Consuelo (Hospital Universitari Joan XXIII de Tarragona) ; Vidal-Gonzalez, J. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Perpiñán, C. (Current address: Atenció Primària ICS. Cap Sant Pere) ; Pacheco, Y.M. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Veloso, S. (Hospital Universitari Joan XXIII de Tarragona) ; Alba, V. (Hospital Universitari Joan XXIII de Tarragona) ; Vargas, M. (Hospital Universitari Joan XXIII de Tarragona) ; Castellano, A.J. (Hospital Universitari Joan XXIII de Tarragona) ; Ruiz-Mateos, E. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Mallolas, Josep (Hospital Clínic i Provincial de Barcelona) ; Vidal, F. (Hospital Universitari Joan XXIII de Tarragona) ; Rull, A. (Hospital Universitari Joan XXIII de Tarragona) ; Universitat Autònoma de Barcelona
A relationship between polymorphisms in genes encoding interleukin 7 (IL-7) and its cellular receptor (IL-7R) and antiretroviral therapy (ART)-associated immune recovery in HIV subjects has been previously reported. [...]
2019 - 10.1038/s41598-019-52025-8
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 15722  
15.
10 p, 3.0 MB CENP-A binding domains and recombination patterns in horse spermatocytes / Cappelletti, Eleonora (Università degli Studi di Pavia. Dipartimento di Biologia e Biotecnologie "L. Spallanzani") ; Piras, Francesca M. (Università degli Studi di Pavia. Dipartimento di Biologia e Biotecnologie "L. Spallanzani") ; Badiale, Claudia (Università degli Studi di Pavia. Dipartimento di Biologia e Biotecnologie "L. Spallanzani") ; Bambi, Marina (Università degli Studi di Pavia. Dipartimento di Biologia e Biotecnologie "L. Spallanzani") ; Santagostino, Marco (Università degli Studi di Pavia. Dipartimento di Biologia e Biotecnologie "L. Spallanzani") ; Vara, Covadonga (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Masterson, Teri A. (National University of Ireland. Centre for Chromosome Biology) ; Sullivan, Kevin F. (National University of Ireland. Centre for Chromosome Biology) ; Nergadze, Solomon G. (Università degli Studi di Pavia. Dipartimento di Biologia e Biotecnologie "L. Spallanzani") ; Ruiz-Herrera Moreno, Aurora (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Giulotto, Elena (Università degli Studi di Pavia. Dipartimento di Biologia e Biotecnologie "L. Spallanzani")
Centromeres exert an inhibitory effect on meiotic recombination, but the possible contribution of satellite DNA to this "centromere effect" is under debate. In the horse, satellite DNA is present at all centromeres with the exception of the one from chromosome 11. [...]
2019 - 10.1038/s41598-019-52153-1
Scientific reports (Nature Publishing Group), Vol. 9, issue 1 (Jan. 2019) , art. 15800  
16.
9 p, 1.3 MB Depression and apathy after transient ischemic attack or minor stroke : prevalence, evolution and predictors / Carnes-Vendrell, Anna (Universitat de Lleida) ; Deus Yela, Juan (Universitat Autònoma de Barcelona. Departament de Psicologia Clínica i de la Salut) ; Molina-Seguin, Jessica (Universitat de Lleida) ; Pifarré, Josep (Universitat de Lleida) ; Purroy, Francisco (Hospital Arnau de Vilanova (Lleida, Catalunya))
Few previous studies have focused on affective impairment after transient ischemic attack (TIA) and/or minor stroke. The aim was to establish the prevalence, evolution and predictors of post-stroke depression (PSD) and post-stroke apathy (PSA) over a 12-month follow-up period. [...]
2019 - 10.1038/s41598-019-52721-5
Scientific reports (Nature Publishing Group), Vol. 9 (january 2019) , p. e16248  
17.
14 p, 2.6 MB Genome Wide Meta-Analysis identifies common genetic signatures shared by heart function and Alzheimer's disease / Sáez, María Eugenia (Centro Andaluz de Estudios Bioinformaticos (CAEBi)) ; González-Pérez, A. (Centro Andaluz de Estudios Bioinformaticos (CAEBi)) ; Hernández-Olasagarre, B. (Institut Català de Neurociènces Aplicades) ; Beà, A. (Institut de Recerca Biomèdica de Lleida) ; Moreno-Grau, Sonia. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; de Rojas, I. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Monté-Rubio, G. (Institut Català de Neurociènces Aplicades) ; Orellana, Adelina (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Valero, S. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Comella i Carnicé, Joan Xavier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sanchís, D. (Institut de Recerca Biomèdica de Lleida) ; Ruiz, A. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Universitat Autònoma de Barcelona
Echocardiography has become an indispensable tool for the study of heart performance, improving the monitoring of individuals with cardiac diseases. Diverse genetic factors associated with echocardiographic measures have been previously reported. [...]
2019 - 10.1038/s41598-019-52724-2
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 16665  
18.
6 p, 1.4 MB Improved Alere Determine Lipoarabinomannan Antigen Detection Test for the Diagnosis of Human and Bovine Tuberculosis by Manipulating Urine and Milk / García, Juan Ignacio (Universitat Autònoma de Barcelona. Departament de Pediatria, d'Obstetrícia i Ginecologia i de Medicina Preventiva) ; Kelley, Holden V. (Texas Biomedical Research Institute) ; Meléndez, Johanna (Roosevelt Hospital) ; Álvarez de León, Rosa Alejandra (Roosevelt Hospital) ; Castillo, Alejandra (Clinica de Atención Integral Dr. Isaac Cohen Alcahe. Hospital de Especialidad Dr. Robles) ; Sidiki, Sabeen (Ohio State University) ; Yusoof, Kizil A. (Texas Biomedical Research Institute) ; Nunes, Elizabete (Hospital Central de Maputo. Division of Pulmonology) ; López Téllez, César (Clinica de Atención Integral Dr. Isaac Cohen Alcahe. Hospital de Especialidad Dr. Robles) ; Mejía Villatoro, Carlos Rodolfo (Roosevelt Hospital) ; Ikeda, Janet (Investigación, Desarrollo y Educación Integral (Quetzaltenango, Guatemala)) ; García-Basteiro, Alberto L (Amsterdam Institute for Global Health and Development) ; Wang, Shu Hua (Ohio State University) ; Torrelles, Jordi B. (Texas Biomedical Research Institute)
Tuberculosis (TB) disease still kills 1-person every 21-seconds. Few TB diagnostic tests are considered truly appropriate for point of care settings. The WHO-endorsed immunodiagnostic Alere Determine Lipoarabinomannan Ag-test (LAM-test) detects Mycobacterium tuberculosis complex LAM in urine, and its use is recommended for TB diagnosis among HIV co-infected individuals with low CD4 T-cell counts. [...]
2019 - 10.1038/s41598-019-54537-9
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 18012  
19.
10 p, 1.9 MB Magnetic resonance microscopy and correlative histopathology of the infarcted heart / Perez-Terol, I. (Instituto de Investigación Sanitaria INCLIVA (Valèna, Comunitat Valenciana)) ; Rios-Navarro, C. (Hospital Clínic Universitari (València)) ; de Dios, E. (Hospital Clínic Universitari (València)) ; Morales, J.M. (Pathology Department. School of Medicine. University of Valencia) ; Gavara Doñate, Jose (Hospital Clínic Universitari (València)) ; Perez-Sole, N. (Hospital Clínic Universitari (València)) ; Diaz, A. (Unidad Central de Investigación Biomédica. University of Valencia) ; Minana, G. (Medicine Department. School of Medicine. University of Valencia) ; Segura-Sabater, R. (Instituto de Investigación Sanitaria INCLIVA (Valèna, Comunitat Valenciana)) ; Bonanad, C. (Medicine Department. School of Medicine. University of Valencia) ; Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Husser, Oliver (St. Johannes Hospital(Alemania)) ; Monmeneu, J.V. (Cardiovascular Magnetic Resonance Unit. ERESA) ; Lopez-Lereu, M.P. (Cardiovascular Magnetic Resonance Unit. ERESA) ; Nunez, J. (Medicine Department. School of Medicine. University of Valencia) ; Chorro, F.J. (Medicine Department. School of Medicine. University of Valencia) ; Ruiz-Sauri, A. (Pathology Department. School of Medicine. University of Valencia) ; Bodi, V. (Medicine Department. School of Medicine. University of Valencia) ; Monleon, D. (Centro de Investigación Biomédica en Red sobre Fragilidad y Envejecimiento Saludable) ; Universitat Autònoma de Barcelona
Delayed enhancement cardiovascular magnetic resonance (MR) is the gold-standard for non-invasive assessment after myocardial infarction (MI). MR microscopy (MRM) provides a level of detail comparable to the macro objective of light microscopy. [...]
2019 - 10.1038/s41598-019-56436-5
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 20017  
20.
12 p, 5.8 MB Restoration of liver sinusoidal cell phenotypes by statins improves portal hypertension and histology in rats with NASH / Bravo, Miren (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Raurell, I. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hide, D. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernández-Iglesias, Anabel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Gil, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Barberá, Aurora (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Salcedo, Maria Teresa (Hospital Universitari Vall d'Hebron) ; Augustin, Salvador (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Genescà, Joan (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Martell, María (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Universitat Autònoma de Barcelona
Non-alcoholic steatohepatitis (NASH) is a common chronic liver disorder in developed countries, with the associated clinical complications driven by portal hypertension (PH). PH may precede fibrosis development, probably due to endothelial dysfunction at early stages of the disease. [...]
2019 - 10.1038/s41598-019-56366-2
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 20183  
21.
11 p, 1.5 MB CIBER-CLAP (CIBERCV Cardioprotection Large Animal Platform) : A multicenter preclinical network for testing reproducibility in cardiovascular interventions / Rossello, X. (Centro Nacional de Investigaciones Cardiovasculares (CNIC)) ; Rodriguez-Sinovas, A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vilahur, G. (Institut d'Investigació Biomèdica Sant Pau) ; Crisóstomo, Verónica (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Jorge, I. (Centro Nacional de Investigaciones Cardiovasculares (CNIC)) ; Zaragoza, C. (Universidad Francisco de Vitoria) ; Zamorano, J.L. (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ; Bermejo, J. (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ; Ordoñez, A. (Instituto de Biomedicina de Sevilla) ; Boscá, L. (Instituto de Investigaciones Biomédicas Alberto Sols (Centro Mixto CSIC-UAM)) ; Vázquez, J. (Centro Nacional de Investigaciones Cardiovasculares (CNIC)) ; Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ; Sánchez-Margallo, F.M. (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Fernandez Aviles, Francesc (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ; García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ibanez, B. (Hospital Universitario Fundación Jiménez Díaz) ; Universitat Autònoma de Barcelona
Despite many cardioprotective interventions have shown to protect the heart against ischemia/reperfusion injury in the experimental setting, only few of them have succeeded in translating their findings into positive proof-of-concept clinical trials. [...]
2019 - 10.1038/s41598-019-56613-6
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 20290  
22.
10 p, 1.4 MB PDGF-BB serum levels are decreased in adult onset Pompe patients / Fernández Simón, Esther (Institut d'Investigació Biomèdica Sant Pau) ; Carrasco-Rozas, Ana (Institut d'Investigació Biomèdica Sant Pau) ; Gallardo, E. (Institut d'Investigació Biomèdica Sant Pau) ; Figueroa-Bonaparte, S. (Institut d'Investigació Biomèdica Sant Pau) ; Belmonte, I. (Institut d'Investigació Biomèdica Sant Pau) ; Pedrosa, I. (Institut d'Investigació Biomèdica Sant Pau) ; Montiel, E. (Institut d'Investigació Biomèdica Sant Pau) ; Suárez-Calvet, X. (Institut d'Investigació Biomèdica Sant Pau) ; Alonso-Pérez, Jorge (Institut d'Investigació Biomèdica Sant Pau) ; Nuñez-Peralta, C. (Institut d'Investigació Biomèdica Sant Pau) ; Llauger, J. (Institut d'Investigació Biomèdica Sant Pau) ; Mayos, M. (Institut d'Investigació Biomèdica Sant Pau) ; Illa, I. (Institut d'Investigació Biomèdica Sant Pau) ; Barba-Romero, M.A. (Complejo Hospitalario Universitario de Albacete) ; Barcena, J. (Hospital Universitario de Cruces (Barakaldo, País Basc)) ; Carzorla, M.R. (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ; Creus, C. (Hospital Universitario Virgen de las Nieves (Granada)) ; Coll-Cantí, Jaume (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; de Luna, N. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Díaz, M. (Hospital de Cabueñes) ; Dominguez, Cristina (Hospital Universitario 12 de Octubre (Madrid)) ; Fernandez-Torron, Roberto (Hospital Universitario de Donostia.(Sant Sebastià, País Basc)) ; García-Antelo, M.J. (Complejo Hospitalario Universitario de A Coruña) ; Grau, J.M. (Hospital Clínic i Provincial de Barcelona) ; Gómez-Caravaca, M.T. (Hospital Universitario Reina Sofía (Córdoba, Espanya)) ; León-Hernández, J.C. (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ; López de Munáin, A. (Hospital Universitario de Donostia.(Sant Sebastià, País Basc)) ; Martínez-García, F.A. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; Morgado, Y. (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; Moreno Camacho, Asunción (Hospital General Universitario Morales Meseguer (Múrcia)) ; Morís, G. (Hospital Universitario de Asturias) ; Muñoz-Blanco, M.A. (Hospital General Universitario Gregorio Marañón) ; Nascimento, A. (Hospital Sant Joan de Déu (Manresa)) ; Paradas, C. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Parajuá-Pozo, J.L. (Hospital de Can Mises) ; Querol, L. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Robledo-Strauss, A. (Hospital Juan Ramón Jiménez (Huelva)) ; Rojas-Garcia, Ricard (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Rojas-Marcos, Í. (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ; Salazar, J.A. (Hospital Regional Universitario de Málaga) ; Usón, Mercedes (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ; Diaz-Manera, Jordi. (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Adult onset Pompe disease is a genetic disorder characterized by slowly progressive skeletal and respiratory muscle weakness. Symptomatic patients are treated with enzymatic replacement therapy with human recombinant alfa glucosidase. [...]
2019 - 10.1038/s41598-018-38025-0
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 2139  
23.
7 p, 1.3 MB Sex differences in the 1 H NMR metabolic profile of serum in cardiovascular risk patients / Barba, Ignasi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Andrés Villarreal (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Picón, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Aguadé-Bruix, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-Dorado, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Personalized diagnosis and risk stratification of cardiovascular diseases would allow optimizing therapeutic strategies and lifestyle changes. Metabolomics is a promising technique for personalized diagnosis and prognosis; however, various physiological parameters, including sex, influence the metabolic profile thus hampering its translation to the clinic. [...]
2019 - 10.1038/s41598-019-38881-4
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 2380  
24.
8 p, 1.1 MB Behçet's disease and genetic interactions between HLA-B*51 and variants in genes of autoinflammatory syndromes / Burillo-Sanz, Sergio (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Montes-Cano, M.A. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; García-Lozano, J.R. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Olivas-Martínez, I. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Ortego-Centeno, Norberto (Hospital Clínico San Cecilio) ; García-Hernández, Francisco-José (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Espinosa, G. (Hospital Clínic i Provincial de Barcelona) ; Graña-Gil, G. (Department of Rheumatology. Complejo Hospitalario Universitario) ; Sánchez-Bursón, J. (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; Juliá, M.R. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ; Solans, Rosa (Hospital Universitari Vall d'Hebron) ; Blanco, R. (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ; Barnosi-Marín, A.C. (Department of Internal Medicine. Complejo Hospitalario Torrecárdenas) ; Gómez de la Torre, R. (Department of Internal Medicine. Hospital Universitario Central de Asturias) ; Fanlo, P. (Hospital Virgen del Camino(Pamplona)) ; Rodríguez-Carballeira, M. (Hospital Universitari MútuaTerrassa) ; Rodriguez-Rodriguez, Luis (Hospital Clínico San Carlos (Madrid)) ; Camps i Miró, Teresa (Department of Internal Medicine. Hospital Regional Universitario) ; Castañeda, S. (Instituto de Investigación Hospital Universitario de la Princesa) ; Alegre-Sancho, Juan José (Hospital Universitari Doctor Peset (València)) ; Martín, J. (Instituto de Parasitología y Biomedicina "López-Neyra") ; González-Escribano, M.F. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Universitat Autònoma de Barcelona
Behçet's disease (BD) is an immune-mediated systemic disorder with a well-established genetic base. In a previous study, using a next generation sequencing approach, we found many rare variants and some functional polymorphisms in genes related to autoinflammatory syndromes (AID): CECR1, MEFV, MVK, NLRP3, NOD2, PSTPIP1 and TNFRSF1A in our BD cohort. [...]
2019 - 10.1038/s41598-019-39113-5
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 2777  
25.
11 p, 1.3 MB Metabolites related to purine catabolism and risk of type 2 diabetes incidence; modifying effects of the TCF7L2-rs7903146 polymorphism / Papandreou, Christopher (Institut d'Investigació Sanitària Pere Virgili) ; Li, Jun (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Liang, Liming (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Bulló, Mònica (Institut d'Investigació Sanitària Pere Virgili) ; Zheng, Yan (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Ruiz-Canela, Miguel (Universidad de Navarra) ; Yu, Edward (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Guasch-Ferré, Marta (Institut d'Investigació Sanitària Pere Virgili) ; Razquin, Cristina (Universidad de Navarra) ; Clish, Clary (Massachusetts Institute of Technology) ; Corella, Dolores (Universitat de València) ; Estruch, Ramon (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ros, Emilio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Fitó, Montserrat (Institut Hospital del Mar d'Investigacions Mèdiques) ; Arós, Fernando (Arabako Unibertsitate Ospitalea) ; Serra-Majem, Lluís (Universidad de Las Palmas de Gran Canaria) ; Rosique, Nuria (Institut d'Investigació Sanitària Pere Virgili) ; Martínez-González, Miguel A (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ; Hu, Frank B (Harvard Medical School) ; Salas-Salvadó, Jordi (Institut d'Investigació Sanitària Pere Virgili) ; Universitat Autònoma de Barcelona
Studies examining associations between purine metabolites and type 2 diabetes (T2D) are limited. We prospectively examined associations between plasma levels of purine metabolites with T2D risk and the modifying effects of transcription factor-7-like-2 (TCF7L2) rs7903146 polymorphism on these associations. [...]
2019 - 10.1038/s41598-019-39441-6
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 2892  
26.
15 p, 2.2 MB Climate and landscape changes as driving forces for future range shift in southern populations of the European badger / Rosalino, L.M. (Universidade de Lisboa. Centre for Ecology, Evolution and Environmental Changes) ; Guedes, D. (Universidade de Aveiro. Departamento de Biologia & CESAM) ; Cabecinha, D. (Universidade de Lisboa. Centre for Ecology, Evolution and Environmental Changes) ; Serronha, A. (Universidade do Porto. Centro de Investigação em Biodiversidade e Recursos Genéticos) ; Grilo, C. (Universidade de Aveiro. Departamento de Biologia & CESAM.) ; Santos-Reis, M. (Universidade de Lisboa. Centre for Ecology, Evolution and Environmental Changes) ; Monterroso, P. (Universidade do Porto. Centro de Investigação em Biodiversidade e Recursos Genéticos) ; Carvalho, João (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ; Fonseca, C. (Universidade de Aveiro. Departamento de Biologia & CESAM) ; Pardavila, X. (Universidade de Santiago de Compostela. Área de Ecoloxía. Departamento de Bioloxía Funcional) ; Virgós, E. (Universidad Rey Juan Carlos. Departamento de Biología. Geología. Física y Química Inorgánica) ; Hipólito, D. (Universidade de Aveiro. Departamento de Biologia & CESAM)
Human-Induced Rapid Environmental Change (HIREC), particularly climate change and habitat conversion, affects species distributions worldwide. Here, we aimed to (i) assess the factors that determine range patterns of European badger (Meles meles) at the southwestern edge of their distribution and (ii) forecast the possible impacts of future climate and landcover changes on those patterns. [...]
2019 - 10.1038/s41598-019-39713-1
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 3155  
27.
12 p, 1.4 MB Controllability affects endocrine response of adolescent male rats to stress as well as impulsivity and behavioral flexibility during adulthood / Sanchís Ollé, Maria (Universitat Autònoma de Barcelona. Unitat de Fisiologia Animal) ; Fuentes, Silvia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Úbeda-Contreras Gallego de la Sacristana, Jesús (Universitat Autònoma de Barcelona. Unitat de Fisiologia Animal) ; F. Lalanza, Jaume (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ; Ramos-Prats, A. (Universitat Autònoma de Barcelona. Unitat de Fisiologia Animal) ; Armario, Antonio (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Nadal, Roser (Universitat Autònoma de Barcelona. Institut de Neurociències)
Exposure to stress during adolescence exerts a long-term impact on behavior and might contribute to the development of several neuropsychiatric disorders. In adults, control over stress has been found to protect from the negative consequences of stress, but the influence of controllability at early ages has not been extensively studied. [...]
2019 - 10.1038/s41598-019-40061-3
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 3180  
28.
16 p, 5.4 MB HER2 and p95HER2 differentially regulate miRNA expression in MCF-7 breast cancer cells and downregulate MYB proteins through miR-221/222 and miR-503 / Gorbatenko, A. (Section for Cell Biology and Physiology. Department of Biology. Faculty of Science. University of Copenhagen) ; Søkilde, R. (Department of Clinical Sciences Lund. Oncology and Pathology. Faculty of Medicine. Lund University) ; Sorensen, E.E. (Section for Cell Biology and Physiology. Department of Biology. Faculty of Science. University of Copenhagen) ; Newie, I. (Department of Clinical Sciences Lund. Oncology and Pathology. Faculty of Medicine. Lund University) ; Persson, H. (Department of Clinical Sciences Lund. Oncology and Pathology. Faculty of Medicine. Lund University) ; Morancho, Beatriz (Vall d'Hebron Institut d'Oncologia) ; Arribas, Joaquín V (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Litman, T. (Department of International Health. Immunology and Microbiology. University of Copenhagen) ; Rovira, Carlos (Department of Clinical Sciences Lund. Oncology and Pathology. Faculty of Medicine. Lund University) ; Pedersen, S.F. (Section for Cell Biology and Physiology. Department of Biology. Faculty of Science. University of Copenhagen)
The HER2 oncogene and its truncated form p95HER2 play central roles in breast cancer. Here, we show that although HER2 and p95HER2 generally elicit qualitatively similar changes in miRNA profile in MCF-7 breast cancer cells, a subset of changes are distinct and p95HER2 shifts the miRNA profile towards the basal breast cancer subtype. [...]
2019 - 10.1038/s41598-019-39733-x
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 3352  
29.
10 p, 1.4 MB Reliable resolution of ambiguous hepatitis C virus genotype 1 results with the Abbott HCV Genotype Plus RUO assay / Saludes, Verónica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Antuori Torres, Adrián (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Reinhardt, B. (Abbott GmbH & Co. KG) ; Viciana, I. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Clavijo, E. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Schreiber, L. (Maccabi Mega-Lab) ; Tenenbaum, M. (Maccabi Mega-Lab) ; Rodriguez-Frias, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Quer, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Matas, L. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martró, Elisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Accurate subtyping of hepatitis C virus genotype 1 (HCV-1) remains clinically and epidemiologically relevant. The Abbott HCV Genotype Plus RUO (GT Plus) assay, targeting the core region, was evaluated as a reflex test to resolve ambiguous HCV-1 results in a challenging sample collection. [...]
2019 - 10.1038/s41598-019-40099-3
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 3678  
30.
11 p, 1.7 MB Use of IP-10 detection in dried plasma spots for latent tuberculosis infection diagnosis in contacts via mail / Villar-Hernández, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Latorre, Irene (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; De Souza-Galvão, Maria Luiza (Hospital Universitari Vall d'Hebron) ; Jiménez, M.A. (Hospital Universitari Vall d'Hebron) ; Ruiz Manzano, J (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pilarte, J. (Hospital Universitari Vall d'Hebron) ; García-García, E. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Muriel-Moreno, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cantos, A. (Hospital Universitari Vall d'Hebron) ; Altet, Neus (Hospital Universitari Vall d'Hebron) ; Millet, J.P. (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; González-Díaz, Y. (Unidad Clínica de Tratamiento Directamente Observado "Serveis Clinics") ; Molina-Pinargote, I. (Unidad Clínica de Tratamiento Directamente Observado "Serveis Clinics") ; Prat i Aymerich, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ruhwald, M. (Statens Serum Institut (Copenhagen, Dinamarca). Department of Infectious Disease Immunology) ; Domínguez, J. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
The aim of this study was to test the use of IP-10 detection in dried plasma from contact studies individuals (contacts of smear positive patients), by comparing it with IP-10 and IFN-γ detection in direct plasma, to establish IP-10 detection in DPS as a useful assay for LTBI diagnosis. [...]
2019 - 10.1038/s41598-019-40778-1
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 3943  
31.
14 p, 3.9 MB Low survival rate and muscle fiber-dependent aging effects in the McArdle disease mouse model / Real-Martinez, A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Brull, A. (Sorbonne Université) ; Huerta, J. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Tarrasó, G. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lucia, A. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Martin, M.A. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Arenas, J. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Andreu, A.L. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Nogales, Gisela (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vissing, J. (University of Copenhagen) ; Krag, Thomas (University of Copenhagen) ; de Luna, N. (Institut d'Investigació Biomèdica Sant Pau) ; Pinós, T. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
McArdle disease is an autosomal recessive disorder caused by the absence of the muscle glycogen phosphorylase, which leads to impairment of glycogen breakdown. The McArdle mouse, a model heavily affected by glycogen accumulation and exercise intolerance, was used to characterize disease progression at three different ages. [...]
2019 - 10.1038/s41598-019-41414-8
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 5116  
32.
10 p, 10.3 MB Nanoscale structure of amyloid-β plaques in Alzheimer's disease / Querol-Vilaseca, M. (Institut d'Investigació Biomèdica Sant Pau) ; Colom-Cadena, Martí (Institut d'Investigació Biomèdica Sant Pau) ; Pegueroles, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Núñez-Llaves, Raúl (Institut d'Investigació Biomèdica Sant Pau) ; Luque-Cabecerans, J. (Institut d'Investigació Biomèdica Sant Pau) ; Muñoz, Laia (Institut d'Investigació Biomèdica Sant Pau) ; Andilla, Jordi (Institut de Ciències Fotòniques) ; Belbin, Olivia (Institut d'Investigació Biomèdica Sant Pau) ; Spires-Jones, T.L. (University of Edinburgh. UK Dementia Research Institute. Centre for Discovery Brain Sciences) ; Gelpi, Ellen (Medical University of Vienna) ; Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Loza-Alvarez, P. (Institut de Ciències Fotòniques) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Soluble amyloid-β (Aβ) is considered to be a critical component in the pathogenesis of Alzheimer's disease (AD). Evidence suggests that these non-fibrillar Aβ assemblies are implicated in synaptic dysfunction, neurodegeneration and cell death. [...]
2019 - 10.1038/s41598-019-41443-3
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 5181  
33.
1 p, 302.0 KB Diferències de forma del zooplàncton del Golf de Mèxic durant l'última desglaciació / Zarkogiannis, Stergios. (National & Kapodistrian University of Athens) ; Antonarakou, A. (National & Kapodistrian University of Athens) ; Tripati, A. (European Institute of Marine Sciences (IUEM)) ; Kontakiotis, George (Panepistēmio Athēnōn. Department of Historical Geology and Paleontology) ; Mortyn, P. Graham (Universitat Autònoma de Barcelona. Departament de Geografia) ; Drinia, Hara (National & Kapodistrian University of Athens) ; Greaves, Mervyn (University of Cambridge)
Especialistes en oceanografia i en l'estudi del canvi climàtic han estudiat restes fòssils de foraminífers planctònics provinents del Golf de Mèxic amb l'objectiu d'investigar la temperatura, salinitat i productivitat oceàniques durant l'última desglaciació. [...]
This study provides evidence that ambient seawater density influences calcification and may account for the observed planktonic foraminifera shell mass increase during glacial times. Volumes of weighed fossil Globigerina bulloides shells were accurately determined using X-ray Computer Tomography and were combined with water density reconstructions from Mg/Ca and δO measurements to estimate the buoyancy force exerted on each shell. [...]
Especialistas en oceanografía y en el estudio del cambio climático han estudiado restos fósiles de foraminíferos planctónicos provenientes del Golfo de México con el objetivo de investigar la temperatura, salinidad y producción oceánicas durante la última desglaciación. [...]

2019 - 10.1038/s41598-018-36935-7
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 533
3 documentos
34.
5 p, 1.1 MB Clinical and laboratory features of anti-MAG neuropathy without monoclonal gammopathy / Pascual-Goñi, Elba (Institut d'Investigació Biomèdica Sant Pau) ; Martín-Aguilar, Lorena (Institut d'Investigació Biomèdica Sant Pau) ; Lleixà, Cinta (Institut d'Investigació Biomèdica Sant Pau) ; Martinez-Martinez, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Simón-Talero, Manuel J. (Institut d'Investigació Biomèdica Sant Pau) ; Diaz-Manera, Jordi. (Institut d'Investigació Biomèdica Sant Pau) ; Cortés-Vicente, Elena (Institut d'Investigació Biomèdica Sant Pau) ; Rojas-Garcia, Ricard (Institut d'Investigació Biomèdica Sant Pau) ; Moga, Esther (Institut d'Investigació Biomèdica Sant Pau) ; Juarez, Candido (Institut d'Investigació Biomèdica Sant Pau) ; Illa, Isabel (Institut d'Investigació Biomèdica Sant Pau) ; Querol, Luis (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Antibodies against myelin-associated glycoprotein (MAG) almost invariably appear in the context of an IgM monoclonal gammopathy associated neuropathy. Very few cases of anti-MAG neuropathy lacking IgM-monoclonal gammopathy have been reported. [...]
2019 - 10.1038/s41598-019-42545-8
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 6155  
35.
6 p, 1.1 MB Legionella SBT applied directly to respiratory samples as a rapid molecular epidemiological tool / Quero, S. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Párraga-Niño, Noemí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sabriá-Leal, M (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Barrabeig, I. (Agència de Salut Pública de Catalunya) ; Sala, M.R. (Agència de Salut Pública de Catalunya) ; Jané, M. (Agència de Salut Pública de Catalunya) ; Mateu, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Sopena, Nieves (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pedro-Botet, M.L. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Garcia-Nuñez, Marian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ; Universitat Autònoma de Barcelona
Legionnaires' disease (LD) is an atypical pneumonia caused by the inhalation of Legionella. The methods used for the diagnosis of LD are direct culture of respiratory samples and urinary antigen detection. [...]
2019 - 10.1038/s41598-018-36924-w
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 623  
36.
9 p, 2.2 MB Antimicrobial removal on piglets promotes health and higher bacterial diversity in the nasal microbiota / Correa-Fiz, Florencia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ; Gonçalves dos Santos, J.M. (Unicesumar-Centro Universitário de Maringá.) ; Illas, F. (Selección Batallé.) ; Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
The view on antimicrobials has dramatically changed due to the increased knowledge on the importance of microbiota composition in different body parts. Antimicrobials can no longer be considered only beneficial, but also potentially deleterious for favourable bacterial populations. [...]
2019 - 10.1038/s41598-019-43022-y
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 6545  
37.
8 p, 1.2 MB GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study / Rongve, A. (The University of Bergen. Department of Clinical Medicine (K1)) ; Witoelar, A. (Institute of Clinical Medicine. University of Oslo) ; Ruiz, A. (Institut Català de Neurociènces Aplicades) ; Athanasiu, L. (Institute of Clinical Medicine. University of Oslo) ; Abdelnour, Carla. (Institut Català de Neurociènces Aplicades) ; Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Heilmann-Heimbach, S. (Department of Genomics. Life & Brain Center. University of Bonn) ; Hernández, Isabel (Institut Català de Neurociènces Aplicades) ; Moreno-Grau, Sonia. (Institut Català de Neurociènces Aplicades) ; de Rojas, I. (Institut Català de Neurociènces Aplicades) ; Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ; Fladby, T. (University of Oslo. AHUS Campus) ; Sando, S.B. (Department of Neuromedicine and Movement Science. Norwegian University of Science and Technology) ; Bråthen, Geir (St Olav's University Hospital) ; Blanc, F. (University of Strasbourg and CNRS. ICube laboratory and FMTS. team IMIS/Neurocrypto) ; Bousiges, O. (University Hospital of Strasbourg. CMRR (Memory Resources and Research Centre). Laboratory of Biochemistry and Molecular Biology) ; Lemstra, A.W. (Amsterdam UMC. University Medical Center) ; van Steenoven, I. (Amsterdam UMC. University Medical Center) ; Londos, Elisabet (Skåne University Hospital (Suècia)) ; Almdahl, I.S. (Oslo University Hospital (Oslo, Noruega)) ; Pålhaugen, L. (University of Oslo. AHUS Campus) ; Eriksen, J.A. (Institute of Clinical Medicine. University of Oslo) ; Djurovic, S. (NORMENT. KG Jebsen Centre for Psychosis Research. Department of Clinical Science. University of Bergen) ; Stordal, E. (Department of Mental Health. Norwegian University of Science and Technology) ; Saltvedt, Ingvild (St Olav's University Hospital) ; Ulstein, I.D. (Oslo University Hospital (Oslo, Noruega)) ; Bettella, Francesco (NORMENT. KG Jebsen Centre for Psychosis Research. Division of Mental Health and Addiction. Oslo University Hospital) ; Desikan, R.S. (Departments of Radiology and Biomedical Imaging. Neurology and Pediatrics. UCSF) ; Idland, A.V. (Institute of Basic Medical Sciences. University of Oslo) ; Toft, M. (Oslo University Hospital (Oslo, Noruega)) ; Pihlstrøm, Lasse (Oslo University Hospital (Oslo, Noruega)) ; Snaedal, J. (Landspitali University Hospital) ; Tárraga, L. (Institut Català de Neurociènces Aplicades) ; Boada, M. (Institut Català de Neurociènces Aplicades) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Stefánsson, Hreinn (DeCODE genetics) ; Stefánsson, Kári (DeCODE genetics) ; Ramírez, A. (Department for Neurodegenerative Diseases and Geriatric Psychiatry. University of Bonn) ; Aarsland, Dag (Center for Age-Related Diseases. Stavanger University Hospital) ; Andreassen, O.A. (Institute of Clinical Medicine. University of Oslo) ; Universitat Autònoma de Barcelona
Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. [...]
2019 - 10.1038/s41598-019-43458-2
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 7013  
38.
13 p, 3.7 MB Expansion of different subpopulations of CD26 −/low T cells in allergic and non-allergic asthmatics / Nieto-Fontarigo, Juan José (Universidade de Santiago de Compostela) ; Salgado, F.J. (Universidade de Santiago de Compostela) ; San-José, M.E. (Complejo Hospitalario Universitario de Santiago de Compostela) ; Cruz Carmona, María Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Valdés, L. (Instituto de Investigación Sanitaria de Santiago (IDIS)) ; Pérez-Díaz, A. (Universidade de Santiago de Compostela) ; Arias, P. (Department of Biochemistry and Molecular Biology. Faculty of Biology-Biological Research Centre (CIBUS). Universidade de Santiago de Compostela) ; Nogueira, M. (Department of Biochemistry and Molecular Biology. Faculty of Biology-Biological Research Centre (CIBUS). Universidade de Santiago de Compostela) ; González-Barcala, F.J. (Instituto de Investigación Sanitaria de Santiago (IDIS)) ; Universitat Autònoma de Barcelona
CD26 displays variable levels between effector (TH ≫ TH > TH > Treg) and naïve/memory (memory > naïve) CD4 T lymphocytes. Besides, IL-6/IL 6R is associated with TH -differentiation and asthma severity. [...]
2019 - 10.1038/s41598-019-43622-8
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (2019) , p. 7556  
39.
10 p, 2.2 MB Different pattern of CSF glial markers between dementia with Lewy bodies and Alzheimer's disease / Morenas Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ; Alcolea, Daniel. (Institut d'Investigació Biomèdica Sant Pau) ; Suárez-Calvet, M. (German Center for Neurodegenerative Diseases (DZNE) Munich) ; Muñoz-Llahuna, L. (Institut d'Investigació Biomèdica Sant Pau) ; Vilaplana, Eduard (Institut d'Investigació Biomèdica Sant Pau) ; Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ; Subirana, Andrea (Institut d'Investigació Biomèdica Sant Pau) ; Querol-Vilaseca, Marta (Institut d'Investigació Biomèdica Sant Pau) ; Carmona Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ; Illán-Gala, Ignacio (Institut d'Investigació Biomèdica Sant Pau) ; Ribosa-Nogué, Roser (Institut d'Investigació Biomèdica Sant Pau) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Haass, C. (Munich Cluster for Systems Neurology (SyNergy)) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
The role of innate immunity in dementia with Lewy bodies (DLB) has been little studied. We investigated the levels in cerebrospinal fluid (CSF) of glial proteins YKL-40, soluble TREM2 (sTREM2) and progranulin in DLB and their relationship with Alzheimer's disease (AD) biomarkers. [...]
2019 - 10.1038/s41598-019-44173-8
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 7803  
40.
5 p, 818.2 KB First evidence for an association between joint hypermobility and excitability in a non-human species, the domestic dog / Bowen, Jonathan (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Fatjó i Ríos, Jaume (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Serpell, J.A. (University of Pennsylvania. School of Veterinary Medicine) ; Bulbena-Cabré, Andrea (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Leighton, Eldin (The Seeing Eye) ; Bulbena, Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
There is a well-established relationship between joint hypermobility and anxiety in humans, that has not previously been investigated in other species. A population of 5575 assistance dogs were scored for both hip hypermobility and 13 behaviour characteristics using previously validated methods. [...]
2019 - 10.1038/s41598-019-45096-0
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 8629  
41.
10 p, 1.0 MB Visual impairment in aging and cognitive decline : experience in a Memory Clinic / Marquié, Marta (Institut Català de Neurociènces Aplicades) ; Castilla-Martí, Miguel (Hospital del Mar (Barcelona, Catalunya)) ; Valero, Sergi (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Martínez, Joan (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Sánchez, Domingo (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Hernández, Isabel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Rosende-Roca, Maitée (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Vargas, Liliana (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Mauleón, Ana (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Rodríguez-Gómez, Octavio (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Abdelnour, Carla. (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Gil Navarro, Silvia (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Santos-Santos, Miguel Angel (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Alegret, Montserrat (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Espinosa, Ana (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Ortega, Gemma (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Pérez-Cordón, Alba (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Sanabria, Ángela (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Roberto, Natalia (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Moreno-Grau, Sonia. (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; de Rojas, Itziar (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Simó, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ciudin, Andrea (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernández, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Orellana, Adelina (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Monté-Rubio, Gemma (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Benaque, Alba (Universitat Internacional de Catalunya. Institut Català de Neurociències Aplicades) ; Ruiz, Agustín (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Tárraga, Luis (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Boada, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Universitat Autònoma de Barcelona. Departament de Medicina
Visual impairment is common in people living with dementia and regular ophthalmological exams may improve their quality of life. We evaluated visual function in a cohort of elderly individuals and analyzed its association with their degree of cognitive impairment. [...]
2019 - 10.1038/s41598-019-45055-9
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 8698  
42.
11 p, 2.4 MB Cholesterol-Lowering Treatment in Chronic Kidney Disease : Multistage Pairwise and Network Meta-Analyses / Herrera Gómez, Francisco (Nephrology. Hospital Virgen de la Concha - Sanidad de Castilla y León) ; Chimeno, M. Montserrat (Internal Medicine. Hospital Virgen de la Concha - Sanidad de Castilla y León) ; Martín García, Débora (Hospital Clínico Universitario (Valladolid)) ; Lizaraso Soto, Frank (Instituto de Investigación de la Facultad de Medicina Humana. Universidad de San Martín de Porres) ; Maurtua Briseño Meiggs, Álvaro (Woodland Medical Practice - NHS) ; Grande Villoria, Jesús (Nephrology. Hospital Virgen de la Concha - Sanidad de Castilla y León) ; Bustamante Munguira, Juan (Hospital Clínico Universitario (Valladolid)) ; Alamartine, Eric (Nephrology. Dialysis and Transplantation. Centre Hospitalier Universitaire de Saint-Etienne) ; Vilardell, Miquel 1946- (Universitat Autònoma de Barcelona. Departament de Medicina) ; Ochoa Sangrador, Carlos (Research unit. Hospital Virgen de la Concha - Sanidad de Castilla y León) ; Álvarez, F. Javier (Hospital Clínico Universitario (Valladolid))
Pairwise and network meta-analyses on the relationship between the efficacy of the use of statins with or without ezetimibe and reductions in low-density lipoprotein cholesterol (LDLc) and C-reactive protein (CRP) in patients with chronic kidney disease (CKD) are presented. [...]
2019 - 10.1038/s41598-019-45431-5
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 8951  
43.
11 p, 2.0 MB Compensated pathogenic variants in coagulation factors VIII and IX present complex mapping between molecular impact and hemophilia severity / Marín, Òscar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Aguirre, Josu (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; de la Cruz, Xavier (Institució Catalana de Recerca i Estudis Avançats) ; Universitat Autònoma de Barcelona
Compensated pathogenic deviations (CPDs) are sequence variants that are pathogenic in humans but neutral in other species. In recent years, our molecular understanding of CPDs has advanced substantially. [...]
2019 - 10.1038/s41598-019-45916-3
Scientific reports (Nature Publishing Group), Vol. 9 Núm. 1 (january 2019) , p. 9538  

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