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Articles publicats 12 registres trobats  La cerca s'ha fet en 0.00 segons. 
1.
12 p, 7.4 MB Boosted Regeneration and Reduced Denervated Muscle Atrophy by NeuroHeal in a Pre-clinical Model of Lumbar Root Avulsion with Delayed Reimplantation / Romeo Guitart, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Forés Vineta, Joaquim (Universitat de Barcelona. Hospital Clínic) ; Navarro, Xavier. (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Casas Louzao, Caty (Universitat Autònoma de Barcelona. Institut de Neurociències)
The "gold standard" treatment of patients with spinal root injuries consists of delayed surgical reconnection of nerves. The sooner, the better, but problems such as injury-induced motor neuronal death and muscle atrophy due to long-term denervation mean that normal movement is not restored. [...]
2017 - 10.1038/s41598-017-11086-3
Scientific reports, Vol. 7 (2017) , art. 12028  
2.
6 p, 921.8 KB Differential distribution of Y-chromosome haplotypes in Swiss and Southern European goat breeds. / Vidal i Fàbrega, Oriol (Universitat de Girona. Departament de Biologia) ; Drögemüller, Cord (University of Bern. Institute of Genetics) ; Obexer-Ruff, Gabriela (Institute of Genetics, University of Bern) ; Reber, Irene (Institute of Genetics, University of Bern) ; Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Martínez Martínez, Amparo (Universidad de Córdoba. Departamento de Genética) ; Bâlteanu, Valentin Adrian (University of Agricultural Sciences and Veterinary Medicine (Cluj-Napoca, Romania)) ; Delgado Bermejo, Juan Vicente (Universidad de Córdoba. Departamento de Genética) ; Eghbalsaied, Shahin (Islamic Azad University.Department of Animal Science (Isfahan, Iran)) ; Landi, Vincenzo (Universidad de Córdoba. Departamento de Genética) ; Goyache Goñi, Félix María (SERIDA-Deva. Área de Genética y Reproducción Animal) ; Traoré, Amadou (Institut de l'Environnement et Recherches Agricoles (Burkina Faso)) ; Pazzola, Michele (University of Sassari. Department of Veterinary Medicine) ; Vacca, Giuseppe Massimo (University of Sassari. Department of Veterinary Medicine) ; Badaoui, Bouabid (Universitat Autònoma de Barcelona. Departament de Genètica Animal) ; Pilla, Fabio (Università del Molise. Dipartimento di Scienze Animali Vegetali e dell'Ambiente) ; D'Andrea, Mariasilvia (Università del Molise. Dipartimento di Scienze Animali Vegetali e dell'Ambiente) ; Álvarez, Isabel (SERIDA-Deva. Área de Genética y Reproducción Animal) ; Capote, Juan (Instituto Canario de Investigaciones Agrarias) ; Sharaf, Abdoallah (Ain Shams University(El Caire, Egipte). Genetic Department) ; Pons Barro, Agueda L. (Institut de Biologia Animal de Baleares) ; Amills i Eras, Marcel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
The analysis of Y-chromosome variation has provided valuable clues about the paternal history of domestic animal populations. The main goal of the current work was to characterize Y-chromosome diversity in 31 goat populations from Central Eastern (Switzerland and Romania) and Southern Europe (Spain and Italy) as well as in reference populations from Africa and the Near East. [...]
2017 - 10.1038/s41598-017-15593-1
Scientific reports, Vol. 7 (2017) , art. 16161  
3.
13 p, 1.8 MB Ligand chain length drives activation of lipid G protein-coupled receptors / Troupiotis-Tsaïlaki, Anastassia (Université Libre de Bruxelles. Laboratoire de Structure et Fonction des Membranes Biologiques) ; Zachmann, Julian (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; González-Gil, Inés (Universidad Complutense de Madrid. Departamento de Química Orgánica I) ; González, Ángel (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Ortega Gutiérrez, Silvia (Universidad Complutense de Madrid. Departamento de Química Orgánica I) ; López-Rodríguez, María L. (Universidad Complutense de Madrid. Departamento de Química Orgánica I) ; Pardo Carrasco, Leonardo (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Govaerts, Cedric (Université Libre de Bruxelles. Laboratoire de Structure et Fonction des Membranes Biologiques)
Sphingosine-1-phosphate (S1P) is a lipid mediator that can activate five cell membrane G proteincoupled receptors (GPCRs) which carry a variety of essential functions and are promising drug targets. S1P is composed of a polar zwitterionic head-group and a hydrophobic alkyl chain. [...]
2017 - 10.1038/s41598-017-02104-5
Scientific reports, Vol. 7 (2017) , art. 2020  
4.
10 p, 1.5 MB Canine Leishmaniasis progression is associated with vitamin D deficiency / Rodríguez-Cortes, Alheli (Universitat Autònoma de Barcelona. Departament de Farmacologia, Terapèutica i Toxicologia) ; Martori Muntsant, Clara (Universitat Autònoma de Barcelona. Departament de Farmacologia, Terapèutica i Toxicologia) ; Martinez-Florez, Alba (Universitat Autònoma de Barcelona. Departament de Farmacologia, Terapèutica i Toxicologia) ; Clop, Alex (Centre de Recerca en Agrigenòmica) ; Amills i Eras, Marcel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Kubejko, J. (Centre de Recerca en Agrigenòmica) ; Llull, J. (Clínica veterinaria Mon Veterinari (Manacor, Balears)) ; Nadal, J.M. (Clínica veterinaria Mon Veterinari (Manacor, Balears)) ; Alberola, Jordi (Alberola i Domingo) (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
The relationship between vitamin D deficiency and the risk of suffering from a plethora of health disorders, ranging from autoimmune processes to infectious diseases has been widely described. Nonetheless, the potential role of vitamin D in visceral leishmaniasis remains uncharacterized. [...]
2017 - 10.1038/s41598-017-03662-4
Scientific reports, Vol. 7 (2017) , art. 3346  
5.
9 p, 875.1 KB Joint QTL mapping and gene expression analysis identify positional candidate genes influencing pork quality traits / González Prendes, Rayner (Centre de Recerca en Agrigenòmica) ; Quintanilla Aguado, Raquel (Institut de Recerca i Tecnologia Agroalimentàries) ; Cánovas Tienda, Ángela (University of Guelph. Department of Animal Biosciences) ; Manunza, Arianna (Universitat Autònoma de Barcelona. Departament de Genètica Animal) ; Cardoso, Tainã Figueiredo (Centre de Recerca en Agrigenòmica) ; Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Noguera Jiménez, José Luis (Institut de Recerca i Tecnologia Agroalimentàries) ; Pena i Subirà, Ramona Natacha (Institut de Recerca i Tecnologia Agroalimentàries) ; Amills i Eras, Marcel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Meat quality traits have an increasing importance in the pig industry because of their strong impact on consumer acceptance. Herewith, we have combined phenotypic and microarray expression data to map loci with potential effects on five meat quality traits recorded in the longissimus dorsi (LD) and gluteus medius (GM) muscles of 350 Duroc pigs, i. [...]
2017 - 10.1038/srep39830
Scientific reports, Vol. 7 (2017) , art. 39830  
6.
9 p, 732.7 KB RNA-seq based detection of differentially expressed genes in the skeletal muscle of Duroc pigs with distinct lipid profiles. / Cardoso, Tainã Figueiredo (Centre de Recerca en Agrigenòmica) ; Cánovas Tienda, Ángela (Centre de Recerca en Agrigenòmica) ; Canela-Xandri, Oriol (Institut de Recerca i Tecnologia Agroalimentàries) ; González Prendes, Rayner (Centre de Recerca en Agrigenòmica) ; Amills i Eras, Marcel (Centre de Recerca en Agrigenòmica) ; Quintanilla Aguado, Raquel (Institut de Recerca i Tecnologia Agroalimentàries)
We have used a RNA-seq approach to investigate differential expression in the skeletal muscle of swine (N=52) with divergent lipid profiles i. e. HIGH (increased intramuscular fat and muscle saturated and monounsaturated fatty acid contents, higher serum lipid concentrations and fatness) and LOW pigs (leaner and with an increased muscle polyunsaturated fatty acid content). [...]
2017 - 10.1038/srep40005
Scientific reports, Vol. 7 (2017) , art. 40005  
7.
11 p, 1.2 MB An exploratory study of predisposing genetic factors for DiGeorge/velocardiofacial syndrome. / Vergés, Laia (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Vidal, Francesca (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Geán, Esther (Hospital Universitari Sant Joan de Déu. Secció de Genètica Clínica) ; Alemany-Schmidt, Alexandra (Hospital Universitari Son Espases (Palma de Mallorc)) ; Oliver Bonet, Maria (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Blanco, Joan (Universitat Autònoma de Barcelona. Unitat de Biologia Cel·lular)
DiGeorge/velocardiofacial syndrome (DGS/VCFS) is a disorder caused by a 22q11. 2 deletion mediated by non-allelic homologous recombination (NAHR) between low-copy repeats (LCRs). We have evaluated the role of LCR22 genomic architecture and PRDM9 variants as DGS/VCFS predisposing factors. [...]
2017 - 10.1038/srep40031
Scientific reports, Vol. 7 (2017) , art. 40031  
8.
10 p, 1.2 MB A new serotonin 5-HT6 receptor antagonist with procognitive activity : importance of a halogen bond interaction to stabilize the binding / González-Vera, Juan A. (Universidad Complutense de Madrid.Departamento de Química Orgánica) ; Medina, Rocio A. (Universidad Complutense de Madrid. Departamento de Química Orgánica) ; Martín-Fontecha, Mar (Universidad Complutense de Madrid. Departamento de Química Orgánica) ; González Wong, Angel (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; De La Fuente, Tania (Universidad Complutense de Madrid. Departamento de Química Orgánica) ; Vázquez-Villa, Henar (Universidad Complutense de Madrid. Departamento de Química Orgánica) ; García-Cárceles, Javier (Universidad Complutense de Madrid. Departamento de Química Orgánica) ; Botta, Joaquín (University of East Anglia. School of Pharmacy (Norwich, Regene Unit)) ; McCormick, Peter J. (University of East Anglia. School of Pharmacy (Norwich, Regene Unit)) ; Benhamú, Bellida (Universidad Complutense de Madrid. Departamento de Química Orgánica) ; Pardo Carrasco, Leonardo (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; López-Rodríguez, Maria L. (Universidad Complutense de Madrid. Departamento de Química Orgánica)
Serotonin 5-HT6 receptor has been proposed as a promising therapeutic target for cognition enhancement though the development of new antagonists is still needed to validate these molecules as a drug class for the treatment of Alzheimer's disease and other pathologies associated with memory deficiency. [...]
2017 - 10.1038/srep41293
Scientific reports, Vol. 7 (2017) , art. 41293  
9.
13 p, 1.6 MB Cell Death Mechanisms in Tumoral and Non-Tumoral Human Cell Lines Triggered by Photodynamic Treatments : Apoptosis, Necrosis and Parthanatos / Soriano Martín, Jorge (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Mora Espí, Inmaculada (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Alea-Reyes, Maria Elisa (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapéutica) ; Pérez-García, L. (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapéutica) ; Barrios, L. (Leonardo) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ibáñez, Elena (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Nogués, C. (Carme) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia)
Cell death triggered by photodynamic therapy can occur through different mechanisms: apoptosis, necrosis or autophagy. However, recent studies have demonstrated the existence of other mechanisms with characteristics of both necrosis and apoptosis. [...]
2017 - 10.1038/srep41340
Scientific reports, Vol. 7 (2017) , art. 41340  
10.
10 p, 1009.2 KB Subjective craving and event-related brain response to olfactory and visual chocolate cues in binge-eating and healthy individuals / Wolz, Ines (Hospital de Bellvitge. Departament de Psiquiatria) ; Sauvaget, Anne (Centre Hospitalier Universitaire de Nantes) ; Granero, Roser (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Mestre Bach, Gemma (Hospital Universitari de Bellvitge) ; Baño, Marta (Hospital Universitari de Bellvitge) ; Martín Romera, Virginia (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Veciana de las Heras, Misericordia (Universitat de Barcelona. Departament de Ciències Clíniques) ; Jiménez-Murcia, Susana (Hospital Universitari de Bellvitge) ; Jansen, A. (Maastricht University. Department of Clinical Psychological Science) ; Roefs, Anne (Maastricht University. Department of Clinical Psychological Science) ; Fernández Aranda, Fernando (Hospital Universitari de Bellvitge)
High-sugar/high-fat foods are related to binge-eating behaviour and especially people with low inhibitory control may encounter elevated difficulties to resist their intake. Incentive sensitization to food-related cues might lead to increased motivated attention towards these stimuli and to cueinduced craving. [...]
2017 - 10.1038/srep41736
Scientific reports, Vol. 7 (2017) , art. 41736  
11.
14 p, 6.3 MB CREB Regulates Distinct Adaptive Transcriptional Programs in Astrocytes and Neurons. / Pardo Fernández, Luis (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Valor, Luis Miguel (Hospital Universitario Puerta del Mar (Cadis, Andalusia)) ; Eraso-Pichot, Abel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barco, Ángel (Universidad Miguel Hernández. Instituto de Neurociencias) ; Golbano Rodríguez, Arantxa (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Hardingham, Giles E. (University of Edinburgh. Dementia Research Institute) ; Masgrau Juanola, Roser (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Galea Rodríguez de Velasco, Elena (Universitat Autònoma de Barcelona. Institut de Neurociències)
The cyclic AMP response element binding protein (CREB) is a primary hub of a activity-driven genetic programs in neurons controlling plasticity, neurogenesis and survival. By contrast, the gene networks coordinated by CREB in astrocytes are Unknown despite the fact that the astrocytic CREB is a also activity-driven and neuroprotective. [...]
2017 - 10.1038/s41598-017-06231
Scientific reports, Vol. 7(2017) , art. 6390  
12.
14 p, 2.9 MB The inhibitory mechanism of Hal3 on the yeast Ppz1 phosphatase : A mutagenesis analysis / Molero Merinero, Cristina (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Casado Vázquez, Carlos (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
The Ser/Thr protein phosphatase (PPase) Ppz1 is an enzyme related to the ubiquitous type-1 PPases (PP1c) but found only in fungi. It is regulated by an inhibitory subunit, Hal3, which binds to its catalytic domain. [...]
2017 - 10.1038/s41598-017-09360-5
Scientific reports, Vol. 7 (2017) , art. 8819  

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