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14 p, 1.7 MB Generating new fanca-deficient hnscc cell lines by genomic editing recapitulates the cellular phenotypes of fanconi anemia / Errazquin, Ricardo (Molecular Oncology Unit. CIEMAT) ; Sieiro, Esther (Molecular Oncology Unit. CIEMAT) ; Moreno Sánchez, Pilar (Molecular Oncology Unit. CIEMAT) ; Ramírez de Haro, Ma. José (Institut d'Investigació Biomèdica Sant Pau) ; Lorz, Corina (Centro de Investigación Biomédica en Red de Cáncer) ; Peral, Jorge (Molecular Oncology Unit. CIEMAT) ; Ortiz, Jessica (Molecular Oncology Unit. CIEMAT) ; Casado, José A. (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ; Roman-Rodriguez, Francisco J. (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ; Hanenberg, Helmut (Heinrich Heine University) ; Río, Paula (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ; Surrallés i Calonge, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Segrelles, Carmen (Centro de Investigación Biomédica en Red de Cáncer) ; Garcia-Escudero, Ramon (Centro de Investigación Biomédica en Red de Cáncer) ; Universitat Autònoma de Barcelona
Fanconi anemia (FA) patients have an exacerbated risk of head and neck squamous cell carcinoma (HNSCC). Treatment is challenging as FA patients display enhanced toxicity to standard treatments, including radio/chemotherapy. [...]
2021 - 10.3390/genes12040548
Genes, Vol. 12 Núm. 4 (april 2021) , p. 548  
Detailed record - Creative Commons

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