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16 p, 3.9 MB Weighted Gene Co-Expression Network Analysis Identifies Key Modules and Hub Genes Associated with Mycobacterial Infection of Human Macrophages / Lu, Lu (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Waddell, Simon J. (University of Sussex. Brighton and Sussex Medical School) ; Boix i Borràs, Esther (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Wei, RanLei (Sichuan University. Laboratory of Omics Technology and Bioinformatics) ; Bhakta, Sanjib (University of London. Department of Biological Sciences)
Tuberculosis (TB) is still a leading cause of death worldwide. Treatments remain unsatisfactory due to an incomplete understanding of the underlying host-pathogen interactions during infection. In the present study, weighted gene co-expression network analysis (WGCNA) was conducted to identify key macrophage modules and hub genes associated with mycobacterial infection. [...]
2021 - 10.3390/antibiotics10020097
Antibiotics, Vol. 10, Num. 2 (February 2021) , art. 97  

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