Published articles

Published articles 1 records found  Search took 0.03 seconds. 
1.
14 p, 787.7 KB A High-Throughput Screening Identifies MicroRNA Inhibitors That Influence Neuronal Maintenance and/or Response to Oxidative Stress / Pallarès-Albanell, Joan (Centre de Regulació Genòmica) ; Zomeño-Abellán, M. Teresa (Centre de Regulació Genòmica) ; Escaramís, Georgia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Pantano, Lorena (Harvard T.H. Chan School of Public Health. Department of Biostatistics) ; Soriano, Aroa (Hospital Universitari Vall d'Hebron) ; Segura, Miguel F. (Hospital Universitari Vall d'Hebron) ; Martí, Eulàlia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Universitat Autònoma de Barcelona
Small non-coding RNAs (sncRNAs), including microRNAs (miRNAs) are important post-transcriptional gene expression regulators relevant in physiological and pathological processes. Here, we combined a high-throughput functional screening (HTFS) platform with a library of antisense oligonucleotides (ASOs) to systematically identify sncRNAs that affect neuronal cell survival in basal conditions and in response to oxidative stress (OS), a major hallmark in neurodegenerative diseases. [...]
2019 - 10.1016/j.omtn.2019.06.007
Molecular Therapy. Nucleic Acids, Vol. 17 (june 2019) , p. 374-387  

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