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$Presence of pyrophosphate in bone from an atypical femoral fracture site$

6 p, 1.3 MB

Presence of pyrophosphate in bone from an atypical femoral fracture site : a case report / Shabestari, Maziar (Institute of Odontology, Oslo) ; Eriksen, Erik Fink (Oslo University Hospital (Oslo, Noruega)) ; Paschalis, Eleftherios P. (Ludwig Boltzmann Institute of Osteology, Hanusch Hospital of WGKK, AUVA Trauma Centre Meidling, Vienna) ; Roschger, Paul (Ludwig Boltzmann Institute of Osteology, Hanusch Hospital of WGKK, AUVA Trauma Centre Meidling, Vienna) ; Gamsjaeger, Sonja (Ludwig Boltzmann Institute of Osteology, Hanusch Hospital of WGKK, AUVA Trauma Centre Meidling, Vienna) ; Klaushofer, Klaus (Ludwig Boltzmann Institute of Osteology, Hanusch Hospital of WGKK, AUVA Trauma Centre Meidling, Vienna) ; Berzlanovich, Andrea (Medical University of Vienna, Vienna) ; Nogués Solán, Xavier (Institut Hospital del Mar d'Investigacions Mèdiques) ; Puig, Lluis (Hospital del Mar (Barcelona, Catalunya)) ; Díez Pérez, Adolfo (Institut Hospital del Mar d'Investigacions Mèdiques) ; Universitat Autònoma de Barcelona
Long-term antiresorptives use has been linked to atypical subtrochanteric and diaphyseal femoral fractures (AFF), the pathogenesis of which is still unknown. In the present case report we present the results of analysis of bone chips from a 74-year old female patient that had been on alendronate, ibandronate and denosumab treatment, and who sustained an atypical femoral fracture, by histology, quantitative backscattered electron imaging, and Raman spectroscopic analysis. [...]
2017 - DOI (Digital Object Identifier)

10.1016/j.bonr.2017.02.006
Bone Reports, Vol. 6 (march 2017) , p. 81-86

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