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Published articles 5 records found  Search took 0.01 seconds. 
1.
13 p, 1.1 MB Immunohistochemistry-Based Taxonomical Classification of Bladder Cancer Predicts Response to Neoadjuvant Chemotherapy / Font, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Domènech, Montserrat (Medical Oncology Department, Fundació Althaia, 08243 Manresa, Spain) ; Benítez, Raquel (Centro Nacional de Investigaciones Oncológicas) ; Rava, Marta (Centro Nacional de Investigaciones Oncológicas) ; Marqués, Miriam (Centro Nacional de Investigaciones Oncológicas) ; Ramirez, Jose Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pineda, Silvia (Centro Nacional de Investigaciones Oncológicas) ; Domínguez-Rodríguez, Sara (Centro Nacional de Investigaciones Oncológicas) ; Gago Ramos, José Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Badal Lafulla, Josep (Pathology Department, Fundació Althaia, 08243 Manresa, Spain) ; Carrato, Cristina (Universitat Autònoma de Barcelona. Facultat de Medicina) ; López, Héctor (Urology Department, Fundació Althaia, 08243 Manresa, Spain) ; Quer, Ariadna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Castellano, Daniel (Hospital Universitario 12 de Octubre (Madrid)) ; Malats, Núria (Centro de Investigación Biomédica en Red de Cáncer) ; Real, Francisco X. (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut)
Background: Platinum-based neoadjuvant chemotherapy (NAC) increases the survival of patients with organ-confined urothelial bladder cancer (UBC). In retrospective studies, patients with basal/squamous (BASQ)-like tumors present with more advanced disease and have worse prognosis. [...]
2020 - 10.3390/cancers12071784
Cancers, Vol. 12 (july 2020)  
Detailed record - Creative Commons
2.
15 p, 2.2 MB Efficacy and Safety of the Combination of Pravastatin and Sorafenib for the Treatment of Advanced Hepatocellular Carcinoma (ESTAHEP Clinical Trial) / Riaño, Ioana (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; Martín, Leticia (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; Varela Calvo, Maria (Hospital Universitario Central de Asturias) ; Serrano, Trinidad (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ; Núñez, Oscar (Hospital Universitario Infanta Sofía (San Sebastián de los Reyes)) ; Mínguez Rosique, Beatriz (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodrigues, Pedro M. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Perugorria, Maria J. (Universidad del País Vasco) ; Banales, Jesus (Basque Foundation for Science) ; Arenas, Joaquín (Biodonostia Osasun Ikerketako Institutura (País Basc)) ; Universitat Autònoma de Barcelona
Pravastatin has demonstrated anti-tumor activity in preclinical and clinical studies. This multicentric randomized double-blind placebo-controlled phase II study (NCT01418729) investigated the efficacy and safety of sorafenib + pravastatin combination on the overall survival (OS) and time to progression (TTP) of patients with advanced hepatocellular carcinoma (aHCC). [...]
2020 - 10.3390/cancers12071900
Cancers, Vol. 12 (july 2020)  
Detailed record - Creative Commons
3.
17 p, 3.9 MB CN133, a Novel Brain-Penetrating Histone Deacetylase Inhibitor, Hampers Tumor Growth in Patient-Derived Pediatric Posterior Fossa Ependymoma Models / Antonelli, Roberta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jiménez Jiménez, Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Riley, Misha (Massachusetts General Hospital (Boston)) ; Servidei, Tiziana (Fondazione Policlinico Universitario "A. Gemelli" (Roma, Itàlia)) ; Riccardi, Riccardo (Fondazione Policlinico Universitario "A. Gemelli" (Roma, Itàlia)) ; Soriano, Aroa (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Roma, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martinez-Saez, Elena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martini, Maurizio (Catholic University of Sacred Heart) ; Ruggiero, Antonio (Fondazione Policlinico Universitario "A. Gemelli" (Roma, Itàlia)) ; Moreno, Lucas (Vall d'Hebron Institut d'Oncologia) ; Sánchez de Toledo Codin, Josep (Vall d'Hebron Institut d'Oncologia) ; Gallego, Soledad (Vall d'Hebron Institut d'Oncologia) ; Bové, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hooker, Jacob M. (Massachusetts General Hospital (Boston)) ; Segura, Miguel F. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Pediatric ependymoma (EPN) is a highly aggressive tumor of the central nervous system that remains incurable in 40% of cases. In children, the majority of cases develop in the posterior fossa and can be classified into two distinct molecular entities: EPN posterior fossa A (PF-EPN-A) and EPN posterior fossa B (PF-EPN-B). [...]
2020 - 10.3390/cancers12071922
Cancers, Vol. 12 (july 2020)  
Detailed record - Creative Commons
4.
27 p, 2.8 MB Tumor Cell-Intrinsic Immunometabolism and Precision Nutrition in Cancer Immunotherapy / Cuyàs, Elisabet (Institut d'Investigació Biomèdica de Girona) ; Verdura, Sara (Institut d'Investigació Biomèdica de Girona) ; Martin-Castillo, Begoña (Institut Català d'Oncologia) ; Alarcón Cor, Tomás (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ; Lupu, Ruth (Mayo Clinic Cancer Center) ; Bosch-Barrera, J (Universitat de Girona. Departament de Ciències Mèdiques) ; Menendez, Javier A. (Institut d'Investigació Biomèdica de Girona)
One of the greatest challenges in the cancer immunotherapy field is the need to biologically rationalize and broaden the clinical utility of immune checkpoint inhibitors (ICIs). The balance between metabolism and immune response has critical implications for overcoming the major weaknesses of ICIs, including their lack of universality and durability. [...]
2020 - 10.3390/cancers12071757
Cancers, Vol. 12, Issue 7 (July 2020) , art. 1757  
Detailed record - Creative Commons
5.
25 p, 1.4 MB Mycobacteria-Based Vaccines as Immunotherapy for Non-urological Cancers / Noguera-Ortega, Estela (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Guallar Garrido, Sandra (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Julián Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The arsenal against different types of cancers has increased impressively in the last decade. The detailed knowledge of the tumor microenvironment enables it to be manipulated in order to help the immune system fight against tumor cells by using specific checkpoint inhibitors, cell-based treatments, targeted antibodies, and immune stimulants. [...]
2020 - 10.3390/cancers12071802
Cancers, Vol. 12, Issue 7 (July 2020) , art. 1802  
Detailed record - Creative Commons

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