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14 p, 6.5 MB Dual role of Lysophosphatidic Acid Receptor 2 (LPA) in amyotrophic lateral sclerosis / Puigdomenech Poch, Maria (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martínez Muriana, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Andrés-Benito, P (Institut d'Investigació Biomèdica de Bellvitge) ; Ferrer, Isidro (Institut d'Investigació Biomèdica de Bellvitge) ; Chun, Jerold (Sanford Burnham Prebys Medical Discovery Institute) ; López Vales, Rubén (Universitat Autònoma de Barcelona. Institut de Neurociències)
Lysophosphatidic acid (LPA) is a pleiotropic extracellular lipid mediator with many physiological functions that signal through six known G protein-coupled receptors (LPA). In the central nervous system (CNS), LPA mediates a wide range of effects including neural progenitor cell physiology, neuronal cell death, axonal retraction, and inflammation. [...]
2021 - 10.3389/fncel.2021.600872
Frontiers in cellular neuroscience, Vol. 15 (March 2021) , art. 600872  
Detailed record - Creative Commons

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