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7 p, 589.2 KB ERK5 and Cell Proliferation : Nuclear Localization Is What Matters / Gomez, Nestor (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Erazo, Tatiana (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
ERK5, the last MAP kinase family member discovered, is activated by the upstream kinase MEK5 in response to growth factors and stress stimulation. MEK5-ERK5 pathway has been associated to different cellular processes, playing a crucial role in cell proliferation in normal and cancer cells by mechanisms that are both dependent and independent of its kinase activity. [...]
2016 - 10.3389/fcell.2016.00105
Frontiers in Cell and Developmental Biology, Vol. 4 (september 2016)  
Detailed record - Creative Commons

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