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13 p, 1.5 MB Evaluation of an O 2-Substituted (1-3)-β-D-Glucan, Produced by Pediococcus parvulus 2.6, in ex vivo Models of Crohn's Disease / Notararigo, Sara (Instituto de Investigación Sanitaria de Santiago (IDIS)) ; Varela, Encarnación (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Otal, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cristobo, Iván (Centro de Investigaciones Biológicas (Madrid)) ; Antolín, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Guarner, Francisco (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Prieto, Alicia (Centro de Investigaciones Biológicas (Madrid)) ; López, Paloma (Centro de Investigaciones Biológicas (Madrid)) ; Universitat Autònoma de Barcelona
1,3-β-glucans are extracellular polysaccharides synthesized by microorganisms and plants, with therapeutic potential. Among them, the O 2-substituted-(1-3)-β-D-glucan, synthesized by some lactic acid bacteria (LAB), has a prebiotic effect on probiotic strains, an immunomodulatory effect on monocyte-derived macrophages, and potentiates the ability of the producer strain to adhere to Caco-2 cells differentiated to enterocytes. [...]
2021 - 10.3389/fmicb.2021.621280
Frontiers in microbiology, Vol. 12 (february 2021)  

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