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Advances in Parkinson's Disease : 200 Years Later / Del Rey, Natalia López-González (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Quiroga-Varela, Ana (Department of Neuroscience, Centro de Investigación Médica Aplicada (CIMA), University of Navarra) ; Garbayo, Elisa (Instituto de Investigación Sanitaria de Navarra) ; Carballo-Carbajal, Iria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fernández-Santiago, Rubén (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Monje, Mariana H. G. (Universidad Autónoma de Madrid. Departamento de Anatomía, Histología y Neurociencia) ; Trigo-Damas, Inés (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Blanco-Prieto, María J. (Instituto de Investigación Sanitaria de Navarra) ; Blesa, Javier (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Universitat Autònoma de Barcelona
When James Parkinson described the classical symptoms of the disease he could hardly foresee the evolution of our understanding over the next two hundred years. Nowadays, Parkinson's disease is considered a complex multifactorial disease in which genetic factors, either causative or susceptibility variants, unknown environmental cues, and the potential interaction of both could ultimately trigger the pathology. [...]
2018 - DOI (Digital Object Identifier)

10.3389/fnana.2018.00113
Frontiers in Neuroanatomy, Vol. 12 (december 2018)

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