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A super-family of transcriptional activators regulates bacteriophage packaging and lysis in Gram-positive bacteria / Quiles Puchalt, Nuria (Instituto de Biomedicina de Valencia (IBV-CSIC)) ; Tormo Más, María Ángeles (Instituto Valenciano de Investigaciones Agrarias) ; Campoy Sánchez, Susana (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Toledo Arana, Alejandro (Universidad Pública de Navarra. Instituto de Agrobiotecnología) ; Monedero, Vicente (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Agroquimica y Tecnologia de Alimentos) ; Lasa, Íñigo (Universidad Pública de Navarra. Instituto de Agrobiotecnología) ; Novick, Richard P. (New York University Medical Center) ; Christie, Gail E. (Virginia Commonwealth University School of Medicine. Department of Microbiology and Immunology) ; Penadés, José R. (University of Glasgow. Institute of Infection, Immunity and Inflammation)
The propagation of bacteriophages and other mobile genetic elements requires exploitation of the phage mechanisms involved in virion assembly and DNA packaging. Here, we identified and characterized four different families of phage-encoded proteins that function as activators required for transcription of the late operons (morphogenetic and lysis genes) in a large group of phages infecting Gram-positive bacteria. [...]
2013 - DOI (Digital Object Identifier)

10.1093/nar/gkt508
Nucleic acids research, Vol. 41, issue 15 (Aug. 2013) , p. 7260-7275

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