Published articles

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40 p, 5.5 MB Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB and Serotonin 5-HT Receptors / Viñals, Xavier (Universitat Pompeu Fabra. Laboratori de Neurofarmacologia) ; Moreno, Estefanía (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Lanfumey, Laurence (Université Paris Descartes. Institut de Psychiatrie et Neurosciences de Paris (UMR 894)) ; Cordomí Montoya, Arnau (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Pastor, Antoni (IMIM-Institut Hospital del Mar d'Investigacions Médiques. Integrative Pharmacology and Systems Neuroscience) ; de La Torre, Rafael (IMIM-Institut Hospital del Mar d'Investigacions Médiques. Integrative Pharmacology and Systems Neuroscience) ; Gasperini, Paola (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED)) ; Navarro, Gemma (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Howell, Lesley A. (University of East Anglia. School of Pharmacy (United Kingdom)) ; Pardo Carrasco, Leonardo (Universitat Autònoma de Barcelona. Laboratori de Medicina Computacional) ; Lluís, Carmen (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Canela, Enric I. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; McCormick, Peter J. (University of East Anglia. School of Pharmacy (United Kingdom)) ; Maldonado, Rafael (Universitat Pompeu Fabra. Laboratori de Neurofarmacologia) ; Robledo, Patricia (IMIM-Institut Hospital del Mar d'Investigacions Médiques. Integrative Pharmacology and Systems Neuroscience)
Activation of cannabinoid CB1 receptors (CBR) by delta9-tetrahydrocannabinol (THC) produces a variety of negative effects with major consequences in cannabis users that constitute important drawbacks for the use of cannabinoids as therapeutic agents. [...]
2015 - 10.1371/journal.pbio.1002194
PLoS Biology, Vol. 13, Num. 7 (July 2015) , art. e1002194  

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