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9 p, 627.3 KB What makes a protein sequence a prion ? / Sabaté, Raimon (Universitat de Barcelona. Departament de Fisicoquímica) ; Rousseau, Frederic (KU Leuven. Department for Cellular and Molecular Medicine) ; Schymkowitz, Joost (KU Leuven. Departement for Cellular and Molecular Medicine) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Typical amyloid diseases such as Alzheimer's and Parkinson's were thought to exclusively result from de novo aggregation, but recently it was shown that amyloids formed in one cell can cross-seed aggregation in other cells, following a prion-like mechanism. [...]
2015 - 10.1371/journal.pcbi.1004013
PLoS computational biology, Vol. 11, Issue 1 (Jan. 2015) , art. e1004013  

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