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10 p, 2.1 MB Inhibition of Neuronal Apoptosis and Axonal Regression Ameliorates Sympathetic Atrophy and Hemodynamic Alterations in Portal Hypertensive Rats / Ezkurdia Garmendia, Nahia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Raurell, Imma (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rodríguez, Sarai (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; González, Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteban, Rafael (Esteban Mur) (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Genescà Ferrer, Joan (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Martell, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
A neuronal pathway participates in the development of portal hypertension: blockade of afferent sensory nerves in portal vein ligated (PVL) rats simultaneously prevents brain cardiovascular regularory nuclei activation, neuromodulator overexpression in superior mesenteric ganglia, sympathetic atrophy of mesenteric innervation and hemodynamic alterations. [...]
2014 - 10.1371/journal.pone.0084374
PloS one, Vol. 9 (january 2014)  
Detailed record - Creative Commons

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