Institut d'Investigació Biomèdica Sant Pau

Institut d'Investigació Biomèdica Sant Pau 139 records found  previous11 - 20nextend  jump to record: Search took 0.01 seconds. 
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18 p, 2.0 MB A Comparison of RNA-Seq Results from Paired Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Glioblastoma Tissue Samples / Esteve-Codina, Anna (Centre de Regulació Genòmica) ; Arpi, Oriol (Institut Hospital del Mar d’Investigacions Mèdiques (IMIM)) ; Martinez-García, Maria (Hospital del Mar. Oncologia mèdica) ; Pineda, Estela (Hospital Clínic. Oncologia mèdica) ; Mallo, Mar (Institut Germans Trias i Pujol. Institut de Recerca Contra la Leucèmia Josep Carreras) ; Gut, Marta (Centre de Regulació Genòmica) ; Carrato, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rovira, Anna (Institut Hospital del Mar d’Investigacions Mèdiques (IMIM)) ; Lopez, Raquel (Hospital Josep Trueta.) ; Tortosa, Avelina (Universitat de Barcelona, Departament d'Infermeria Fonamental) ; Dabad, Marc (Centre de Regulació Genòmica) ; Del Barco, Sonia (Institut Català d'Oncologia) ; Heath, Simon (Centre de Regulació Genòmica) ; Bagué, Silvia (Institut d'Investigació Biomèdica Sant Pau) ; Ribalta, Teresa (Hospital Clínic) ; Alameda, Francesc (Hospital del Mar) ; de la Iglesia, Nuria (Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS)) ; Balaña, Carmen (Institut Germans Trias i Pujol. Institut Català d'Oncologia) ; on behalf of the GLIOCAT Group ; Glioma Catalonia Group (GLIOCAT) ; Universitat Autònoma de Barcelona
The molecular classification of glioblastoma (GBM) based on gene expression might better explain outcome and response to treatment than clinical factors. Whole transcriptome sequencing using next-generation sequencing platforms is rapidly becoming accepted as a tool for measuring gene expression for both research and clinical use. [...]
2017 - 10.1371/journal.pone.0170632
Plos one, 2017, p. 1-18  
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13 p, 787.1 KB Monoaminergic impairment in Down syndrome with Alzheimer's disease compared to early-onset Alzheimer's disease / Dekker, Alain D. (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Vermeiren, Yannick (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Carmona-Iragui, Maria (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; Benejam, Bessy (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; Videla, Laura (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; Gelpi, Ellen (Neurological Tissue Bank—Biobanc, Hospital Clinic Barcelona, Institut d'Investigacions Biomediques August Pi i Sunyer, Barcelona, Spain) ; Aerts, Tony (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Van Dam, Debby (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Fernández, Susana (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; Lleó Bisa, Alberto (Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain) ; Videla, Sebastian (Faculty of Health and Life Sciences, Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Barcelona, Spain) ; Sieben, Anne (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Martin, Jean-Jacques (Laboratory of Neurochemistry and Behaviour, Institute Born-Bunge, University of Antwerp, Wilrijk, Antwerp, Belgium) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Fortea, Juan (Down Medical Center, Catalan Down Syndrome Foundation, Barcelona, Spain) ; De Deyn, Peter P. (Department of Neurology and Memory Clinic, Hospital Network Antwerp (ZNA) Middelheim and Hoge Beuken, Antwerp, Belgium)
People with Down syndrome (DS) are at high risk for Alzheimer's disease (AD). Defects in monoamine neurotransmitter systems are implicated in DS and AD but have not been comprehensively studied in DS. [...]
2017 - 10.1016/j.dadm.2017.11.001
Alzheimer's Dementia : Diagnosis, Assessment Disease Monitoring, Vol. 10 (november 2017) , p. 99-111  
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23 p, 1.3 MB The behavioral and psychological symptoms of dementia in Down syndrome (BPSD-DS) scale : comprehensive assessment of psychopathology in Down syndrome / Dekker, Alain D. (Universitair Medisch Centrum Groningen) ; Sacco, Silvia (Institut Jérôme Lejeune) ; Carfi, Angelo (Universitá Cattolica del Sacro Cuore) ; Benejam, Bessy (Fundació Catalana Síndrome de Down) ; Vermeiren, Yannick (Universitair Medisch Centrum Groningen) ; Beugelsdijk, Gonny (Ipse de Bruggen) ; Schippers, Mieke (Ipse de Bruggen) ; Hassefras, Lyanne (Ipse de Bruggen) ; Eleveld, José (Cosis (Groningen)) ; Grefelman, Sharina (Cosis (Groningen)) ; Fopma, Roelie (Talant (Heerenveen)) ; Bomer-Veenboer, Monique (Pameijer (Rotterdam)) ; Boti, Mariángeles (Fundació Catalana Síndrome de Down) ; Oosterling, G. Danielle E. (Aveleijn (Borne)) ; Scholten, Esther (Elver (Nieuw-Wehl)) ; Tollenaere, Marleen (Institute Born-Bunge) ; Checkley, Laura (University College London. Division of Psychiatry) ; Strydom, André (University College London. Division of Psychiatry) ; Van Goethem, Gert (Het GielsBos (Gierle)) ; Onder, Graziano (Universitá Cattolica del Sacro Cuore) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; zu Eulenburg, Christine (Universitair Medisch Centrum Groningen) ; Coppus, Antonia M.W. (Dichterbij (Gennep)) ; Rebillat, Anne-Sophie (Institut Jérôme Lejeune) ; Fortea, Juan (Fundació Catalana Síndrome de Down) ; De Deyn, Peter P. (Universitair Medisch Centrum Groningen) ; Universitat Autònoma de Barcelona
People with Down syndrome (DS) are prone to develop Alzheimer's disease (AD). Behavioral and psychological symptoms of dementia (BPSD) are core features, but have not been comprehensively evaluated in DS. [...]
2018 - 10.3233/JAD-170920
Journal of Alzheimer's disease, Vol. 63, issue 2 (2018) , p. 797-819  
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3 p, 155.4 KB Head and voice tremor improving with immunotherapy in an anti‐155 positive patient / Painous, Cèlia (Institut d'Investigació Biomèdica Sant Pau) ; López‐Pérez, Mª Ángeles (Hospital San Pedro) ; Illa, Isabel (Institut d'Investigació Biomèdica Sant Pau) ; Querol, Luis (Institut d'Investigació Biomèdica Sant Pau)
Chronic inflammatory demyelinating polyradiculoneuropathy with 155 antibodies (anti‐155+) constitutes a specific chronic inflammatory demyelinating polyradiculoneuropathy subset with a high incidence of limb's tremor and poor response to conventional therapies. [...]
2018 - 10.1002/acn3.539
Annals of Clinical and Translational Neurology, Vol. 5 (march 2018) , p. 499-501  
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3 p, 604.1 KB Complete Resolution of Symptoms of Primary Orthostatic Tremor with Perampanel / Ruiz Julián, María (Institut d'Investigació Biomèdica Sant Pau) ; Orozco, Jorge Luís (Institut d'Investigació Biomèdica Sant Pau) ; Gironell, Alexandre (Institut d'Investigació Biomèdica Sant Pau)
Primary orthostatic tremor (POT) is an infrequent disorder whose physiopathology is unknown. Current medication is largely ineffective or only offers mild benefits. A 75-year-old female with refractory POT treated with 4 mg/day of perampanel achieved complete symptom resolution. [...]
2018 - 10.7916/D8QZ3SZD
Tremor and Other Hyperkinetic Movements, Vol. 8 (april 2018)  
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11 p, 5.6 MB Summation and Cancellation Effects on QRS and ST-Segment Changes Induced by Simultaneous Regional Myocardial Ischemia / Vives-Borrás, Miquel (Institut d'Investigació Biomèdica Sant Pau) ; Jorge, Esther (Institut d'Investigació Biomèdica Sant Pau) ; Amorós-Figueras, Gerard (Institut d'Investigació Biomèdica Sant Pau) ; Millán, Xavier (Institut d'Investigació Biomèdica Sant Pau) ; Arzamendi, Dabit (Institut d'Investigació Biomèdica Sant Pau) ; Cinca, Juan (Institut d'Investigació Biomèdica Sant Pau)
Simultaneous ischemia in two myocardial regions is a potentially lethal clinical condition often unrecognized whose corresponding electrocardiographic (ECG) patterns have not yet been characterized. Thus, this study aimed to determine the QRS complex and ST-segment changes induced by concurrent ischemia in different myocardial regions elicited by combined double occlusion of the three main coronary arteries. [...]
2018 - 10.3389/fphys.2018.00275
Frontiers in Physiology, Vol. 9 (april 2018)  
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13 p, 475.3 KB Reciprocal Effects of Antiretroviral Drugs Used To Treat HIV Infection on the Fibroblast Growth Factor 21/β-Klotho System / Moure, Ricardo (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ; Villarroya, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Gasa, Laura (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Gallego-Escuredo, José M. (Institut de Recerca Biomèdica (IRB) de Lleida) ; Quesada-López, Tania (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Morón-Ros, Samantha (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Maroto, Alberto F. (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Mateo, Gracia M. (Institut d'Investigació Biomèdica Sant Pau) ; Domingo, Joan C. (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Villarroya, Francesc (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Giralt, Marta (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Universitat Autònoma de Barcelona
Following antiretroviral therapy, HIV-infected patients show increased circulating levels of the antidiabetic hormone fibroblast growth factor 21 (FGF21). In contrast, the expression of the FGF21-obligatory coreceptor β-Klotho (KLB) is reduced in target tissues. [...]
2018 - 10.1128/AAC.00029-18
Antimicrobial Agents and Chemotherapy, Vol. 62 (may 2018)  
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7 p, 951.5 KB Role of cooperative groups and funding source in clinical trials supporting guidelines for systemic therapy of breast cancer / Tibau, Ariadna (Institut d'Investigació Biomèdica Sant Pau) ; Anguera, Geòrgia (Institut d'Investigació Biomèdica Sant Pau) ; Andrés-Pretel, Fernando (Research Foundation of the Paraplegics Hospital of Toledo, Toledo, Spain) ; Templeton, Arnoud J. (Department of Medical Oncology, St Claraspital, Basel and Faculty of Medicine, University of Basel, Basel, Switzerland) ; Seruga, Bostjan (Department of Medical Oncology, Institute of Oncology Ljubljana and University of Ljubljana, Ljubljana, Slovenia) ; Barnadas, Agustí (Institut d'Investigació Biomèdica Sant Pau) ; Amir, Eitan (Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, Toronto, Ontario, Canada) ; Ocana, Alberto (Translational Research Unit, Albacete University Hospital, Centro Regional de Investigaciones Biomédicas, Universidad de Castilla La Mancha, CIBERONC, Albacete, Spain)
Clinical research is conducted by academia, cooperative groups (CGs) or pharmaceutical industry. Here, we evaluate the role of CGs and funding sources in the development of guidelines for breast cancer therapies. [...]
2018 - 10.18632/oncotarget.24589
Oncotarget, Vol. 9 (february 2018) , p. 15061-15067  
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7 p, 481.9 KB Risk category system to identify pituitary adenoma patients with AIP mutations / Caimari, Francisca (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya). Departament d'Endocrinologia) ; Hernández-Ramírez, Laura Cristina (Queen Mary University of London. William Harvey Research Institute) ; Dang, Mary N (Queen Mary University of London. William Harvey Research Institute) ; Gabrovska, Plamena (Queen Mary University of London. William Harvey Research Institute) ; Iacovazzo, Donato (Queen Mary University of London. William Harvey Research Institute) ; Stals, Karen (Royal Devon & Exeter Hospital) ; Ellard, Sian (Royal Devon & Exeter Hospital) ; Korbonits, Márta (Queen Mary University of London. William Harvey Research Institute) ; Universitat Autònoma de Barcelona
Predictive tools to identify patients at risk for gene mutations related to pituitary adenomas are very helpful in clinical practice. We therefore aimed to develop and validate a reliable risk category system for aryl hydrocarbon receptor-interacting protein (AIP) mutations in patients with pituitary adenomas. [...]
2018 - 10.1136/jmedgenet-2017-104957
Journal of medical genetics, Vol. 55, issue 4 (April 2018) , p. 254-260  
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9 p, 590.6 KB A baseline metabolomic signature is associated with immunological CD4 + T-cell recovery after 36 months of antiretroviral therapy in HIV-infected patients / Rodríguez-Gallego, Esther (Hospital Universitari Joan XXIII) ; Gómez, Josep (Hospital Universitari Joan XXIII) ; Pacheco, Yolanda M. (Instituto de Biomedicina de Sevilla) ; Peraire, Joaquim (Hospital Universitari Joan XXIII) ; Viladés, Consuelo (Hospital Universitari Joan XXIII) ; Beltrán Debón, Raúl (Hospital Universitari Joan XXIII) ; Mallol, Roger (Universitat Rovira i Virgili. Departament d'Enginyeria Electrònica) ; López Dupla, Miguel (Hospital Universitari Joan XXIII) ; Veloso, Sergi (Hospital Universitari Joan XXIII) ; Alba, Verónica (Hospital Universitari Joan XXIII) ; Blanco, Julià (Institut Germans Trias i Pujol. Fundació IrsiCaixa) ; Cañellas, Nicolau (Universitat Rovira i Virgili. Departament d'Enginyeria Electrònica) ; Rull, Anna (Hospital Universitari Joan XXIII) ; Leal, Manuel (Instituto de Biomedicina de Sevilla) ; Correig, Xavier (Universitat Rovira i Virgili. Departament d'Enginyeria Electrònica) ; Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ; Vidal, Francesc (Hospital Universitari Joan XXIII)
Poor immunological recovery in treated HIV-infected patients is associated with greater morbidity and mortality. To date, predictive biomarkers of this incomplete immune reconstitution have not been established. [...]
2018 - 10.1097/QAD.0000000000001730
AIDS (London, England), Vol. 32 (march 2018) , p. 565-573  

Institut d'Investigació Biomèdica Sant Pau : 139 records found   previous11 - 20nextend  jump to record:
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