Institut d'Investigació Biomèdica Sant Pau

Institut d'Investigació Biomèdica Sant Pau 142 records found  beginprevious21 - 30nextend  jump to record: Search took 0.00 seconds. 
21.
7 p, 951.5 KB Role of cooperative groups and funding source in clinical trials supporting guidelines for systemic therapy of breast cancer / Tibau, Ariadna (Institut d'Investigació Biomèdica Sant Pau) ; Anguera, Geòrgia (Institut d'Investigació Biomèdica Sant Pau) ; Andrés-Pretel, Fernando (Research Foundation of the Paraplegics Hospital of Toledo, Toledo, Spain) ; Templeton, Arnoud J. (Department of Medical Oncology, St Claraspital, Basel and Faculty of Medicine, University of Basel, Basel, Switzerland) ; Seruga, Bostjan (Department of Medical Oncology, Institute of Oncology Ljubljana and University of Ljubljana, Ljubljana, Slovenia) ; Barnadas, Agustí (Institut d'Investigació Biomèdica Sant Pau) ; Amir, Eitan (Division of Medical Oncology and Hematology, Department of Medicine, Princess Margaret Cancer Centre and the University of Toronto, Toronto, Ontario, Canada) ; Ocana, Alberto (Translational Research Unit, Albacete University Hospital, Centro Regional de Investigaciones Biomédicas, Universidad de Castilla La Mancha, CIBERONC, Albacete, Spain)
Clinical research is conducted by academia, cooperative groups (CGs) or pharmaceutical industry. Here, we evaluate the role of CGs and funding sources in the development of guidelines for breast cancer therapies. [...]
2018 - 10.18632/oncotarget.24589
Oncotarget, Vol. 9 (february 2018) , p. 15061-15067  
22.
7 p, 481.9 KB Risk category system to identify pituitary adenoma patients with AIP mutations / Caimari, Francisca (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya). Departament d'Endocrinologia) ; Hernández-Ramírez, Laura Cristina (Queen Mary University of London. William Harvey Research Institute) ; Dang, Mary N (Queen Mary University of London. William Harvey Research Institute) ; Gabrovska, Plamena (Queen Mary University of London. William Harvey Research Institute) ; Iacovazzo, Donato (Queen Mary University of London. William Harvey Research Institute) ; Stals, Karen (Royal Devon & Exeter Hospital) ; Ellard, Sian (Royal Devon & Exeter Hospital) ; Korbonits, Márta (Queen Mary University of London. William Harvey Research Institute) ; Universitat Autònoma de Barcelona
Predictive tools to identify patients at risk for gene mutations related to pituitary adenomas are very helpful in clinical practice. We therefore aimed to develop and validate a reliable risk category system for aryl hydrocarbon receptor-interacting protein (AIP) mutations in patients with pituitary adenomas. [...]
2018 - 10.1136/jmedgenet-2017-104957
Journal of medical genetics, Vol. 55, issue 4 (April 2018) , p. 254-260  
23.
9 p, 590.6 KB A baseline metabolomic signature is associated with immunological CD4 + T-cell recovery after 36 months of antiretroviral therapy in HIV-infected patients / Rodríguez-Gallego, Esther (Hospital Universitari Joan XXIII) ; Gómez, Josep (Hospital Universitari Joan XXIII) ; Pacheco, Yolanda M. (Instituto de Biomedicina de Sevilla) ; Peraire, Joaquim (Hospital Universitari Joan XXIII) ; Viladés, Consuelo (Hospital Universitari Joan XXIII) ; Beltrán Debón, Raúl (Hospital Universitari Joan XXIII) ; Mallol, Roger (Universitat Rovira i Virgili. Departament d'Enginyeria Electrònica) ; López Dupla, Miguel (Hospital Universitari Joan XXIII) ; Veloso, Sergi (Hospital Universitari Joan XXIII) ; Alba, Verónica (Hospital Universitari Joan XXIII) ; Blanco, Julià (Institut Germans Trias i Pujol. Fundació IrsiCaixa) ; Cañellas, Nicolau (Universitat Rovira i Virgili. Departament d'Enginyeria Electrònica) ; Rull, Anna (Hospital Universitari Joan XXIII) ; Leal, Manuel (Instituto de Biomedicina de Sevilla) ; Correig, Xavier (Universitat Rovira i Virgili. Departament d'Enginyeria Electrònica) ; Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ; Vidal, Francesc (Hospital Universitari Joan XXIII)
Poor immunological recovery in treated HIV-infected patients is associated with greater morbidity and mortality. To date, predictive biomarkers of this incomplete immune reconstitution have not been established. [...]
2018 - 10.1097/QAD.0000000000001730
AIDS (London, England), Vol. 32 (march 2018) , p. 565-573  
24.
15 p, 4.6 MB Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease / Zarei, Mohammad (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapèutica) ; Barroso, Emma (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapèutica) ; Palomer, Xavier (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapèutica) ; Dai, Jianli (University of the Chinese Academy of Sciences. Institute for Nutritional Sciences. Key Laboratory of Nutrition and Metabolism,) ; Rada, Patricia (Instituto de Salud Carlos III. Centro de Investigación Biomédica en Red) ; Quesada-López, Tania (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Escolà-Gil, Joan Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biología Molecular) ; Cedó, Lidia (Institut d'Investigació Biomèdica Sant Pau) ; Zali, Mohammad Reza (Shahid Beheshti University of Medical Sciences. Research Institute for Gastroenterology and Liver Diseases) ; Molaei, Mahsa (Shahid Beheshti University of Medical Sciences. Research Institute for Gastroenterology and Liver Diseases) ; Dabiri, Reza (Semnan University of Medical Sciences. lnternal Medicine Department) ; Vázquez, Santiago (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapèutica) ; Pujol, Eugènia (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapèutica) ; Valverde, Ángela M. (Instituto de Investigaciones Biomédicas Alberto Sols) ; Villarroya, Francesc (Universitat de Barcelona. Departament de Bioquímica i Biomedicina Molecular) ; Liu, Yong (Wuhan University. Institute for Advanced Studies) ; Wahli, Walter (Nanyang Technological University. Lee Kong Chian School of Medicine) ; Vázquez-Carrera, Manuel (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapèutica)
The very low-density lipoprotein receptor (VLDLR) plays an important role in the development of hepatic steatosis. In this study, we investigated the role of Peroxisome Proliferator-Activated Receptor (PPAR)β/δ and fibroblast growth factor 21 (FGF21) in hepatic VLDLR regulation. [...]
2018 - 10.1016/j.molmet.2017.12.008
Molecular metabolism, Vol. 8 (Feb. 2018) , p. 117-131  
25.
8 p, 357.7 KB Concordance of blood- and tumor-based detection of RAS mutations to guide anti-EGFR therapy in metastatic colorectal cancer / Grasselli, J (Institut Català d'Oncologia) ; Élez Fernández, Mª Elena (Universitat Autònoma de Barcelona) ; Caratù, G (Vall d'Hebron Institut d'Oncologia) ; Matito, J (Vall d'Hebron Institut d'Oncologia) ; Santos, C (Institut Català d'Oncologia) ; Macarulla Mercadé, Teresa (Universitat Autònoma de Barcelona. Hospital Universitari de la Vall d'Hebron) ; Vidal, J (Hospital del Mar. Departament d'Oncologia) ; Garcia, M (Institut Català d'Oncologia) ; Viéitez, J M (Hospital Universitario de Asturias. Departamento de Oncologia Médica) ; Paéz, D (Institut d'Investigació Biomèdica Sant Pau) ; Falcó, E (Hospital Universitari Son Llatzer. Departament d'Oncologia Mèdica) ; Lopez Lopez, C (Hospital Universitario Marqués de Valdecilla. Departamento de Oncología Médica) ; Aranda, E (Hospital Universitario Reina Sofía (Córdoba). Departamento de Oncología Médica) ; Jones, F (Sysmex Inostics, Mundelein, USA) ; Sikri, V (Sysmex Inostics, Mundelein, USA) ; Nuciforo, Paolo (Vall d'Hebron Institut d'Oncologia) ; Fasani, R (Vall d'Hebron Institut d'Oncologia) ; Tabernero Caturla, Josep (Universitat Autònoma de Barcelona) ; Montagut, C (Hospital del Mar. Departament d'Oncologia) ; Azuara, D (Institut Català d'Oncologia) ; Dienstmann, Rodrigo (Vall d'Hebron Institut d'Oncologia) ; Salazar, R (Institut Català d'Oncologia) ; Vivancos, A (Vall d'Hebron Institut d'Oncologia)
Circulating tumor DNA (ctDNA) is a potential source for tumor genome analysis. We explored the concordance between the mutational status of RAS in tumor tissue and ctDNA in metastatic colorectal cancer (mCRC) patients to establish eligibility for anti-epidermal growth factor receptor (EGFR) therapy. [...]
2017 - 10.1093/annonc/mdx112
Annals of Oncology, Vol. 28 (march 2017) , p. 1294-1301  
26.
9 p, 1.5 MB Advances and unmet needs in genetic, basic and clinical science in Alport syndrome : report from the 2015 International Workshop on Alport Syndrome / Gross, Oliver (University Medicine Goettingen (Germany)) ; Kashtan, Clifford E. (University of Minnesota Medical School (USA)) ; Rheault, Michelle N. (University of Minnesota Medical School (USA)) ; Flinter, Frances (Guy's and St Thomas' NHS Foundation Trust (United Kingdom)) ; Savige, Judith (The University of Melbourne (Australia)) ; Miner, Jeffrey H. (Washington University School of Medicine (USA)) ; Torra, Roser (Institut d'Investigació Biomèdica Sant Pau) ; Ars, Elisabet (Institut d'Investigació Biomèdica Sant Pau) ; Deltas, Constantinos (University of Cyprus) ; Savva, Isavella (University of Cyprus) ; Perin, Laura (University of Southern California, Children's Hospital Los Angeles (USA)) ; Renieri, Alessandra (University of Siena (Italy)) ; Ariani, Francesca (University of Siena (Italy)) ; Mari, Francesca (University of Siena (Italy)) ; Baigent, Colin (University of Oxford (United Kingdom)) ; Judge, Parminder (University of Oxford (United Kingdom)) ; Knebelman, Bertrand (Université Paris Descartes (France)) ; Heidet, Laurence (Clinique Maurice Lamy, Hôpital Necker-Enfants Malades (France)) ; Lagas, Sharon (Alport Syndrome Foundation (USA)) ; Blatt, Dave (Alport Foundation of Australia) ; Ding, Jie (Peking University First Hospital (China)) ; Zhang, Yanqin (Peking University First Hospital (China)) ; Gale, Daniel P. (University College London-Centre for Nephrology (United Kingdom)) ; Prunotto, Marco (F. Hoffmann-La Roche Ltd. Roche Pharma Research & Early Development (Switzerland)) ; Xue, Yong (Global Clinical Development. Sanofi Genzyme (The Netherlands)) ; Schachter, Asher D. (Novartis Institutes for BioMedical Research (USA)) ; Morton, Lori C.G. (Regeneron Pharmaceuticals (USA)) ; Blem, Jacqui (Regulus Therapeutics (USA)) ; Huang, Michael (Regulus Therapeutics (USA)) ; Liu, Shiguang (Sanofi-Genzyme R&D Center (USA)) ; Vallee, Sebastien (Discovery Biology. Shire (USA)) ; Renault, Daniel (FEDERG (Belgium)) ; Schifter, Julia (Alport Israel) ; Skelding, Jules (Alport UK (United Kingdom)) ; Gear, Susie (Alport UK (United Kingdom)) ; Friede, Tim (University Medical Center Goettingen (Germany)) ; Turner, A. Neil (University of Edinburgh (United Kingdom)) ; Lennon, Rachel (University of Manchester (United Kingdom)) ; Universitat Autònoma de Barcelona
Alport syndrome (AS) is a genetic disease characterized by haematuric glomerulopathy variably associated with hearing loss and anterior lenticonus. It is caused by mutations in the COL4A3, COL4A4 or COL4A5 genes encoding the α3α4α5(IV) collagen heterotrimer. [...]
2017 - 10.1093/ndt/gfw095
Nephrology Dialysis Transplantation, Vol. 32, Issue 6 (June 2017) , p. 916-924  
27.
16 p, 1.9 MB Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers / Muñoz, Jose (Barcelona Institute for Global Health, ISGlobal-CRESIB, Universitat de Barcelona. Barcelona, Spain) ; Ballester, Maria Rosa (Institut d'Investigació Biomèdica Sant Pau) ; Antonijoan, Rosa Maria (Universitat Autònoma de Barcelona. Departament de Farmacoloia, Terapèutic i Toxicologia) ; Gich, Ignasi (Universitat Autònoma de Barcelona. Departament de Farmacoloia, Terapèutic i Toxicologia) ; Rodríguez, Montse (Institut d'Investigació Biomèdica Sant Pau) ; Colli, Enrico (ExeltisPharma, Chemo group. Madrid, Spain) ; Gold, Silvia (Fundacion Mundo Sano, Buenos Aires, Argentina) ; Krolewiecki, Alejandro J. (Instituto de Investigaciones en Enfermedades Tropicales, Universidad Nacional de Salta/CONICET, Oran, Argentina)
ClinicalTrials. gov . Current efforts for the control of poverty-related diseases provide drug treatments through mass drug administration (MDA) as a key component. Ivermectin is an antiparasitary drug which has been used to fight some of these diseases, and millions of treatments have been distributed with a favorable toxicity profile. [...]
2018 - 10.1371/journal.pntd.0006020
PLoS Neglected Tropical Diseases, Vol. 12 (january 2018)  
28.
5 p, 280.6 KB DNA Methylation in Stroke. Update of Latest Advances / Krupinski, Jerzy (School of Healthcare Science, Manchester Metropolitan University, Manchester, United Kingdom) ; Carrera, Caty (Neurovascular Research Laboratory, Institut de Recerca, Universitat Autònoma de Barcelona, Hospital Vall d'Hebron, Barcelona, Spain) ; Muiño, Elena (Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mutua Terrassa, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain) ; Torres, Nuria (Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mutua Terrassa, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain) ; Al-Baradie, Raid (Applied Medical Sciences College Majmaah University, Majmaah, Saudi Arabia) ; Cullell, Natalia (Stroke Pharmacogenomics and Genetics, Fundació Docència i Recerca Mutua Terrassa, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau)
Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. [...]
2017 - 10.1016/j.csbj.2017.12.001
Computational and Structural Biotechnology Journal, Vol. 16 (december 2017) , p. 1-5  
29.
7 p, 226.4 KB Improving patient outcomes in psoriasis : strategies to ensure treatment adherence / Yélamos, Oriol (Institut d'Investigació Biomèdica Sant Pau) ; Ros, Sandra (Institut d'Investigació Biomèdica Sant Pau) ; Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau)
Psoriasis is a frequent inflammatory disease with a chronic and relapsing course. Therefore, patients with psoriasis are likely to undergo different treatments for long periods of time. Traditionally, therapies used in psoriasis have been associated with poor levels of adherence due to the complexity of the regimens and the poor results obtained with the topical therapies. [...]
2015 - 10.2147/PTT.S54070
Psoriasis (Auckland, N.Z.), Vol. 5 (july 2015) , p. 109-115  
30.
7 p, 303.7 KB Chromosome 17 Centromere Duplication and Responsiveness to Anthracycline-Based Neoadjuvant Chemotherapy in Breast Cancer / Tibau, Ariadna (Institut d'Investigació Biomèdica Sant Pau) ; López Vilaró, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Pérez-Olabarria, Maitane (Institut d'Investigació Biomèdica Sant Pau) ; Vázquez, Tania (Institut d'Investigació Biomèdica Sant Pau) ; Pons, Cristina (Institut d'Investigació Biomèdica Sant Pau) ; Gich, Ignasi (Institut d'Investigació Biomèdica Sant Pau) ; Alonso, Carmen (Institut d'Investigació Biomèdica Sant Pau) ; Ojeda, Belén (Institut d'Investigació Biomèdica Sant Pau) ; Ramón y Cajal, Teresa (Institut d'Investigació Biomèdica Sant Pau) ; Lerma Puertas, Enrique (Institut d'Investigació Biomèdica Sant Pau) ; Barnadas, Agustí (Institut d'Investigació Biomèdica Sant Pau) ; Escuin, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Human epidermal growth factor receptor 2 (HER2) and topoisomerase II alpha (TOP2A) genes have been proposed as predictive biomarkers of sensitivity to anthracycline chemotherapy. Recently, chromosome 17 centromere enumeration probe (CEP17) duplication has also been associated with increased responsiveness to anthracyclines. [...]
2014 - 10.1016/j.neo.2014.08.012
Neoplasia (New York, N.Y.), Vol. 16 (october 2014) , p. 861-867  

Institut d'Investigació Biomèdica Sant Pau : 142 records found   beginprevious21 - 30nextend  jump to record:
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