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2 p, 193.7 KB Ibrutinib repurposing : from B-cell malignancies to solid tumors / Massó Vallés, Daniel (Vall d'Hebron Institut d'Oncologia) ; Jauset González, Toni (Vall d'Hebron Institut d'Oncologia) ; Soucek, Laura (Vall d'Hebron Institut d'Oncologia) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Ibrutinib (Imbruvica®, also known as PCI-32765) is a first-in-class, irreversible small-molecule inhibitorof Bruton's Tyrosine Kinase (BTK) that binds covalently to cysteine C481 within the ATP-binding pocket. [...]
2016 - 10.18632/oncoscience.310
Oncoscience, Vol. 3, Num. 5-6 (may 2016) , p. 147-148  
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