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6 p, 1.0 MB Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells / Alvarez Berdugo, Daniel (Universitat Autònoma de Barcelona) ; Jiménez Farrerons, Marcel (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Clavé i Civit, Pere (Universitat Autònoma de Barcelona) ; Rofes, Laia (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)
Purpose. TRPV1 is a multimodal channel mainly expressed in sensory neurons. We aimed to explore the pharmacodynamics of the TRPV1 agonists, capsaicin, natural capsaicinoids, and piperine in an in vitro bioassay using human PC-3 cells and to examine desensitization and the effect of the specific antagonist SB366791. [...]
2014 - 10.1155/2014/184526
The Scientific World Journal, Vol. 2014 (February 2014) , art. 184526  
Detailed record - Creative Commons

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