Artículos

Artículos Encontrados 167 registros  inicioanterior65 - 74siguientefinal  ir al registro: La búsqueda tardó 0.00 segundos. 
65.
20 p, 2.9 MB Pharmacokinetic parameters and mechanism of action of an efficient anti-Aβ single chain antibody fragment / Esquerda-Canals, Gisela (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martí-Clúa, Joaquín (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Villegas Hernández, Sandra (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The success of the targeting of amyloid-β (Aβ) oligomers through immunotherapy in Alzheimer's disease (AD) mouse models has not been translated into the clinics. The use of single- chain variable fragments (scFvs) has been proposed to prevent the potential severe effects of full-length mAbs by precluding crystallizable fraction-mediated microglia activation. [...]
2019 - 10.1371/journal.pone.0217793
PloS one, Vol. 14, Issue 5 (May 2019) , art. e0217793  
66.
15 p, 1.8 MB C-mannosylation supports folding and enhances stability of thrombospondin repeats / Shcherbakova, Aleksandra (Medizinische Hochschule Hannover. Institut für Klinische Biochemie) ; Preller, Matthias (Medizinische Hochschule Hannover. Institut für Biophysikalische Chemie) ; Taft, Manuel H. (Medizinische Hochschule Hannover. Institut für Biophysikalische Chemie) ; Pujols Pujol, Jordi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ventura, Salvador (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Tiemann, Birgit (Medizinische Hochschule Hannover. Institut für Klinische Biochemie) ; Buettner, Falk F. R. (Medizinische Hochschule Hannover. Institut für Klinische Biochemie) ; Bakker, Hans (Medizinische Hochschule Hannover. Institut für Klinische Biochemie)
Previous studies demonstrated importance of C-mannosylation for efficient protein secretion. To study its impact on protein folding and stability, we analyzed both C-mannosylated and non-C-mannosylated thrombospondin type 1 repeats (TSRs) of netrin receptor UNC-5. [...]
2019 - 10.7554/eLife.52978
eLife, Vol. 8 (Dec. 2019) , art. e52978  
67.
8 p, 2.9 MB Aggrescan3D (A3D) 2.0 : prediction and engineering of protein solubility / Kuriata, Aleksander (Centrum Nauk Biologiczno-Chemicznych Uniwersytetu Warszawskiego) ; Iglesias, Valentin (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Pujols Pujol, Jordi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Kurcinski, Mateusz (Centrum Nauk Biologiczno-Chemicznych Uniwersytetu Warszawskiego) ; Kmiecik, Sebastian (Centrum Nauk Biologiczno-Chemicznych Uniwersytetu Warszawskiego) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Protein aggregation is a hallmark of a growing number of human disorders and constitutes a major bottleneck in the manufacturing of therapeutic proteins. Therefore, there is a strong need of in-silico methods that can anticipate the aggregative properties of protein variants linked to disease and assist the engineering of soluble protein-based drugs. [...]
2019 - 10.1093/nar/gkz321
Nucleic acids research, Vol. 47, issue W1 (July 2019) , p. W300-W307  
68.
18 p, 145.6 KB Changes of salivary biomarkers under different storage conditions : Effects of temperature and length of storage / Barranco, Tomás (Universidad de Murcia. Interlab-UMU) ; Rubio, C. P. (Universidad de Murcia. Interlab-UMU) ; Tvarijonaviciute, Asta (Universidad de Murcia. Interlab-UMU) ; Rubio, Mónica (Universidad CEU Cardenal Herrera. Departamento de Medicina y Cirugía Animal) ; Damia, E. (Universidad CEU Cardenal Herrera. Departamento de Medicina y Cirugía Animal) ; Lamy, Elsa (Universidad de Evora. Institute of Mediterranean Agricultural and Environmental Sciences (ICAAM)) ; Cugat, R. (Hospital Quirónsalud Barcelona) ; Cerón, José Joaquín (Universidad de Murcia. Interlab-UMU) ; Tecles, Fernando (Universidad de Murcia. Interlab-UMU) ; Escribano Tortosa, Damián (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Introduction: In this report, we aimed to examine the stability of various analytes in saliva under different storage conditions. Materials and methods: Alpha-amylase (AMY), cholinesterase (CHE), lipase (Lip), total esterase (TEA), creatine kinase (CK), aspartate aminotransferase (AST), lactate dehydrogenase (LD), lactate (Lact), adenosine deaminase (ADA), Trolox equivalent antioxidant capacity (TEAC), ferric reducing ability (FRAS), cupric reducing antioxidant capacity (CUPRAC), uric acid (UA), catalase (CAT), advanced oxidation protein products (AOPP) and hydrogen peroxide (H O) were colorimetrically measured in saliva obtained by passive drool from 12 healthy voluntary donors at baseline and after 3, 6, 24, 72 hours, 7 and 14 days at room temperature (RT) and 4 ºC, and after 14 days, 1, 3 and 6 months at - 20 ºC and - 80 ºC. [...]
2019 - 10.11613/BM.2019.010706
Biochemia medica, Vol. 29 Núm. 1 (2019) , p. 10706  
69.
11 p, 295.2 KB Periodic solutions of a class of Duffing differential equations / Benterki, Rebiha (Université de Bordj Bou Arréridj. Département de Mathématiques (Algeria)) ; Llibre, Jaume (Universitat Autònoma de Barcelona. Departament de Matemàtiques)
In this work we study the existence of new periodic solutions for the well knwon class of Duffing differential equation of the form x" + cx' + a(t)x + b(t)x3 = h(t), where c is a real parameter, a(t), b(t) and h(t) are continuous T-periodic functions. [...]
2019 - 10.12150/jnma.2019.167
Journal of Nonlinear Modeling and Analysis, Vol. 1, Issue 2 (June 2019) , p. 167-177  
70.
16 p, 342.0 KB Periodic solutions of the Duffing differential equation revisited via the averaging theory / Benterki, Rebiha (Université de Bordj Bou Arréridj. Département de Mathématiques (Algeria)) ; Llibre, Jaume (Universitat Autònoma de Barcelona. Departament de Matemàtiques)
We use three different results of the averaging theory of first order for studying the existence of new periodic solutions in the two Duffing differential equations ¨ y + asiny = bsint and ¨ y + ay−cy3 = bsint, where a, b and c are real parameters.
2019 - 10.12150/jnma.2019.11
Journal of Nonlinear Modeling and Analysis, Vol. 1, Issue 1 (March 2019) , p. 11-26  
71.
9 p, 3.3 MB Unraveling the Impact of Halide Mixing on Perovskite Stability / Hieulle, Jeremy (Okinawa Institute of Science and Technology Graduate University) ; Wang, Xiaoming (University of Toledo. Department of Physics and Astronomy and Wright) ; Stecker, Collin (Okinawa Institute of Science and Technology Graduate University) ; Son, Dae-Yong (Okinawa Institute of Science and Technology Graduate University) ; Qiu, Longbin (Okinawa Institute of Science and Technology Graduate University) ; Ohmann, Robin (Okinawa Institute of Science and Technology Graduate University) ; Ono, Luis K. (Okinawa Institute of Science and Technology Graduate University) ; Mugarza, Aitor (Institut Català de Nanociència i Nanotecnologia) ; Yan, Yanfa (University of Toledo. Department of Physics and Astronomy and Wright) ; Qi, Yabing (Okinawa Institute of Science and Technology Graduate University)
Increasing the stability of perovskites is essential for their integration in commercial photovoltaic devices. Halide mixing is suggested as a powerful strategy toward stable perovskite materials. However, the stabilizing effect of the halides critically depends on their distribution in the mixed compound, a topic that is currently under intense debate. [...]
2019 - 10.1021/jacs.8b11210
Journal of the American Chemical Society, Vol. 141, Issue 8 (February 2019) , p. 3515-3523  
72.
8 p, 1.2 MB Thin film oxide-ion conducting electrolyte for near room temperature applications / Garbayo, Íñigo (Institut de Recerca en Energia de Catalunya) ; Chiabrera, Francesco Maria (Institut de Recerca en Energia de Catalunya) ; Alayo Bueno, Nerea (Institut de Recerca en Energia de Catalunya) ; Santiso, José (Institut Català de Nanociència i Nanotecnologia) ; Morata, Alex (Institut de Recerca en Energia de Catalunya) ; Tarancón Rubio, Albert (Institut de Recerca en Energia de Catalunya)
Stabilized bismuth vanadate thin films are presented here as superior oxide ionic conductors, for application in solid state electrochemical devices operating near room temperature. Widely studied in the 90s in bulk form due to their unbeatable ionic conduction, this family of materials was finally discarded due to poor stability above 500 °C. [...]
2019 - 10.1039/c9ta07632h
Journal of materials chemistry, Vol. 7, Issue 45 (December 2019) , p. 25772-25778  
73.
16 p, 466.5 KB Spectral stability of periodic waves in the generalized reduced Ostrovsky equation / Geyer, Anna (Delft University of Technology. Delft Institute of Applied Mathematics (The Netherlands)) ; Pelinovsky, Dmitry E. (Nizhny Novgorod State Technical University. Department of Applied Mathematics (Russia))
We consider stability of periodic travelling waves in the generalized reduced Ostrovsky equation with respect to co-periodic perturbations. Compared to the recent literature, we give a simple argument that proves spectral stability of all smooth periodic travelling waves independent of the nonlinearity power. [...]
2017 - 10.1007/s11005-017-0941-3
Letters in mathematical physics, Vol. 107, Issue 7 (July 2017) , p. 1293-1314
2 documentos
74.
52 p, 1.1 MB Soil restoration using compost-like-outputs and digestates from non-source-separated urban waste as organic amendments : limitations and opportunities / Carabassa, Vicenç (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Domene, Xavier (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Alcañiz, Josep M. (Josep Maria) (Centre de Recerca Ecològica i d'Aplicacions Forestals)
Soil rehabilitation in the context of the restoration of quarries, dumping sites, or road slopes often requires the prior addition of organic amendments to improve the substrates used for Technosol construction. [...]
2020 - 10.1016/j.jenvman.2019.109909
Journal of environmental management, Vol. 255 (Feb. 2020) , art. 109909  

Artículos : Encontrados 167 registros   inicioanterior65 - 74siguientefinal  ir al registro:
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