Results overview: Found 6 records in 0.02 seconds.
Articles, 5 records found
Research literature, 1 records found
Articles 5 records found  
1.
25 p, 4.2 MB Cx43 and Associated Cell Signaling Pathways Regulate Tunneling Nanotubes in Breast Cancer Cells / Tishchenko, Alexander (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Azorín, Daniel D. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vidal-Brime, Laia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; José Muñoz, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jiménez Arenas, Pol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pearce, Christopher (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Girao, Henrique (University of Coimbra. Faculty of Medicine) ; Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Aasen, Trond (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Connexin 43 (Cx43) forms gap junctions that mediate the direct intercellular diffusion of ions and small molecules between adjacent cells. Cx43 displays both pro- and anti-tumorigenic properties, but the mechanisms underlying these characteristics are not fully understood. [...]
2020 - 10.3390/cancers12102798
Cancers, Vol. 12 Núm. 10 (2020) , p. 2798  
2. / Sesé, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Fuentes, Pedro (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Esteve-Codina, Anna (CNAG-CRG, Centre for Genomic Regulation, Barcelona Institute of Science and Technology, Universitat Pompeu Fabra, Barcelona, Spain) ; Béjar, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; McGrail, Kimberley (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Thomas, George (Physiological Sciences Department, Faculty of Medicine and Health Science, University of Barcelona, Barcelona, Spain) ; Aasen, Trond (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Breast cancer is the most prevalent malignancy in women and there is an urgent need for new therapeutic drugs targeting aggressive and metastatic subtypes, such as hormone-refractory triple-negative breast cancer (TNBC). [...]
2017 - 10.18632/oncotarget.23145
Oncotarget, Vol. 8 (december 2017) , p. 114856-114876  
21 p, 5.1 MB
3.
18 p, 2.6 MB Interplay between YB-1 and IL-6 promotes the metastatic phenotype in breast cancer cells / Castellana, Bàrbara (Departments of Department of Obstetrics and Gynecology, Child and Family Research Institute, University of British Columbia) ; Aasen, Trond (Vall d'Hebron Institut de Recerca. Patologia molecular) ; Moreno-Bueno, Gema (Instituto de Investigaciones Biomédicas "Alberto Sols" CSIC-UAM) ; Dunn, Sandra E. (Phoenix Molecular Diagnostics Ltd., Richmond) ; Ramón y Cajal, Santiago (Vall d'Hebron Institut de Recerca (VHIR). Patologia molecular) ; Universitat Autònoma de Barcelona
Epithelial to mesenchymal transition (EMT) induces cell plasticity and promotes metastasis. The multifunctional oncoprotein Y-box binding protein-1 (YB-1) and the pleiotropic cytokine interleukin 6 (IL-6) have both been implicated in tumor cell metastasis and EMT, but via distinct pathways. [...]
2015
Oncotarget, Vol. 6 (october 2015) , p. 38239-38256  
4.
6 p, 646.3 KB Internal translation of the connexin 43 transcript / Salat-Canela, Clàudia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sesé, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Peula, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ramón y Cajal, Santiago (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Aasen, Trond (Molecular Hospital Universitari Vall d'Hebron. Institut de Recercan) ; Universitat Autònoma de Barcelona
Connexin 43 (Cx43), the most widely expressed gap junction protein, is associated with a number of physiological and pathological conditions. Many functions of Cx43 have been shown to be independent of gap junction formation and only require the expression of Cx43 C-terminal fragments. [...]
2014 - 10.1186/1478-811X-12-31
Cell Communication and Signaling : CCS, Vol. 12 (may 2014) , p. 31  
5.
39 p, 2.8 MB Disease-corrected haematopoietic progenitors from Fanconi anemia induced pluripotent stem cells / Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Rodríguez-Pizà, Ignasi (Center for Regenerative Medicine in Barcelona) ; Guenechea, Guillermo (Networking Center of Biomedical Research in Rare Diseases (CIBERER)) ; Vassena, Rita (Center for Regenerative Medicine in Barcelona) ; Navarro, Susana (Networking Center of Biomedical Research in Rare Diseases (CIBERER)) ; Barrero, María José (Center for Regenerative Medicine in Barcelona) ; Consiglio, Antonella (University of Brescia. Department of Biomedical Science and Biotechnology) ; Castellà, Maria (Universitat Autònoma de Barcelona. Department of Genetics and Microbiology) ; Río, Paula (Networking Center of Biomedical Research in Rare Diseases (CIBERER)) ; Sleep, Eduard (Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN)) ; González, Federico (Center for Regenerative Medicine in Barcelona) ; Tiscornia, Gustavo (Center for Regenerative Medicine in Barcelona) ; Garreta, Elena (Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN)) ; Aasen, Trond (Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN)) ; Veiga, Anna (Center for Regenerative Medicine in Barcelona) ; Verma, Inder M. (Laboratory of Genetics, Salk Institute for Biological Studies) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Bueren, Juan (Hematopoiesis and Gene Therapy Division, Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT)) ; Izpisúa Belmonte, Juan Carlos (Gene Expression Laboratory, Salk Institute for Biological Studies)
The generation of induced pluripotent stem (iPS) cells by ectopic expression of a defined set of factors1-5 has enabled the derivation of patient-specific pluripotent cells and provided valuable experimental platforms to model human disease6-8. [...]
2009 - 10.1038/nature08129
Nature, Núm. 460 (05 2009) , p. 53-59  

Research literature 1 records found  
1.
218 p, 9.7 MB Estudio de la fosforilación de eIF4E y del factor 4E-T en situaciones de estrés celular en cáncer de mama / Martínez Díaz, Alba ; Ramón y Cajal, Santiago, dir. ; Aasen, Trond ; Anna, Meseguer ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
En los últimos años se ha descrito la desregulación de la síntesis proteica en muchas enfermedades, esto ha incrementado la investigación de nuevos mecanismos que controlan la expresión génica, en particular a nivel del inicio de la traducción. [...]
Deregulated protein synthesis has been described in many diseases in recent years, stimulating further research into the mechanisms that control gene expression, in particular at the level of translational initiation. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2014  

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1 Aasen, Trond.
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