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5 p, 722.3 KB Copper Modulation as a Therapy for Alzheimer's Disease? / Manso Sanz, Yasmina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Comes Orpinell, Gemma (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Hidalgo Pareja, Juan (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bush, Ashley I. (The Mental Health Research Institute. Oxidation Biology Laboratory (Australia)) ; Adlard, Paul A. (The University of Melbourne. Department of Pathology (Australia)) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
The role of metals in the pathophysiology of Alzheimer's disease (AD) has gained considerable support in recent years, with both in vitro and in vivo data demonstrating that a mis-metabolism of metal ions, such as copper and zinc, may affect various cellular cascades that ultimately leads to the development and/or potentiation of AD. [...]
2011 - 10.4061/2011/370345
International Journal of Alzheimer's Disease, Vol. 2011 (June 2011) , art. 370345  

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