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15 p, 2.4 MB Genome-wide analyses of aggressiveness in attention-deficit hyperactivity disorder / Brevik, Erlend J. (Universitetet i Bergen) ; van Donkelaar, Marjolein M. J. (Donders Institute for Brain, Cognition and Behaviour) ; Weber, Heike (Goethe Universität Frankfurt am Main. Klinik für Psychiatrie, Psychosomatik und Psychotherapie) ; Sánchez Mora, Cristina (Hospital Universitari Vall d'Hebron) ; Jacob, Christian (Klinik Nürtingen. Abteilung für Psychiatrie und Psychotherapie) ; Rivero, Olga (Universität Würzburg. Zentrum fuer Psychische Gesundheit) ; Kittel-Schneider, Sarah (Universität Würzburg. Zentrum fuer Psychische Gesundheit) ; Garcia Martínez, Iris (Hospital Universitari Vall d'Hebron) ; Aebi, Marcel (Psychiatrische Universitätsklinik Zürich) ; van Hulzen, Kimm (Donders Institute for Brain, Cognition and Behaviour) ; Cormand, Bru (Universitat de Barcelona. Departament de Genètica) ; Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Lesch, Klaus-Peter (Klinik Nürtingen. Abteilung für Psychiatrie und Psychotherapie) ; Reif, Andreas (Goethe Universität Frankfurt am Main. Klinik für Psychiatrie, Psychosomatik und Psychotherapie) ; Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron) ; Franke, Barbara (Donders Institute for Brain, Cognition and Behaviour) ; Posserud, Maj-Britt (Universitetet i Bergen) ; Johansson, Stefan (Haukeland universitetssykehus) ; Lundervold, Astri J. (Universitetet i Bergen. Senter for nevropsykiatrisk forskning) ; Haavik, Jan (Universitetet i Bergen) ; Zayats, Tetyana (Universitetet i Bergen. Senter for nevropsykiatrisk forskning)
Aggressiveness is a behavioral trait that has the potential to be harmful to individuals and society. With an estimated heritability of about 40%, genetics is important in its development. We performed an exploratory genome-wide association (GWA) analysis of childhood aggressiveness in attention deficit hyperactivity disorder (ADHD) to gain insight into the underlying biological processes associated with this trait. [...]
2016 - 10.1002/ajmg.b.32434
American journal of medical genetics, Vol. 171, issue 5 (July 2016) , p. 733-747  

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