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14 p, 1.0 MB Withdrawal of inhaled corticosteroids in COPD patients : Rationale and algorithms / Avdeev, S. (Clinical Department. Federal Pulmonology Research Institute. Federal Medical and Biological Agency of Russia) ; Aisanov, Z. (Department of Pulmonology. N.I. Pirogov Russian State National Research Medical University) ; Arkhipov, V. (Department of Clinical Pharmacology and Therapy. Russian Medical Academy of Continuous Professional Education) ; Belevskiy, A. (Department of Pulmonology. N.I. Pirogov Russian State National Research Medical University) ; Leshchenko, I. (Department of Phthisiology. Pulmonology and Thoracic Surgery. Ural State Medical University) ; Ovcharenko, S. (Department of Internal Diseases No.1. I.M. Sechenov First Moscow State Medical University) ; Shmelev, E. (Department of Differential Diagnostics. Federal Central Research Institute of Tuberculosis) ; Miravitlles, Marc. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Observational studies indicate that overutilization of inhaled corticosteroids (ICS) is common in patients with chronic obstructive pulmonary disease (COPD). Overprescription and the high risk of serious ICS-related adverse events make withdrawal of this treatment necessary in patients for whom the treatment-related risks outweigh the expected benefits. [...]
2019 - 10.2147/COPD.S207775
International journal of COPD, Vol. 14 (2019) , p. 1267-1280  
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