Resultados globales: 3 registros encontrados en 0.02 segundos.
Artículos, Encontrados 3 registros
Artículos Encontrados 3 registros  
1.
18 p, 2.2 MB Aberrant epigenome in ‐derived dopaminergic neurons from Parkinson's disease patients / Fernández‐Santiago, Rubén (Universitat de Barcelona) ; Carballo‐Carbajal, Iria (Vall d'Hebron Institut de Recerca (VHIR)) ; Castellano, Giancarlo (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Torrent, Roger (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Richaud, Yvonne (Biomaterials and Nanomedicine (CIBER‐BBN). Centre for Networked Biomedical Research on Bioengineering) ; Sánchez‐Danés, Adriana (Universitat de Barcelona. Institut de Biomedicina (IBUB)) ; Vilarrasa‐Blasi, Roser (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Sánchez‐Pla, Alex (Vall d'Hebron Institut de Recerca (VHIR)) ; Mosquera, José Luis (Universitat de Barcelona) ; Soriano, Jordi (Universitat de Barcelona) ; López‐Barneo, José (Universidad de Sevilla. Hospital Universitario Virgen del Rocío.) ; Canals, Josep M (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Alberch, Jordi (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Raya, Ángel (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Vila Bover, Miquel (Vall d'Hebron Institut de Recerca (VHIR)) ; Consiglio, Antonella (University of Brescia and National Institute of Neuroscience) ; Martín‐Subero, José I (Universitat de Barcelona. Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Ezquerra, Mario (Universitat de Barcelona. Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Tolosa, Eduardo (Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED)) ; Universitat Autònoma de Barcelona
The epigenomic landscape of Parkinson's disease () remains unknown. We performed a genomewide methylation and a transcriptome studies in induced pluripotent stem cell ()‐derived dopaminergic neurons (n) generated by cell reprogramming of somatic skin cells from patients with monogenic 2‐associated (L2) or sporadic (), and healthy subjects. [...]
2015 - 10.15252/emmm.201505439
EMBO Molecular Medicine, Vol. 7, Núm. 12 (October 2015) , p. 1529-1546  
2.
16 p, 1020.6 KB Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like behavior and panic reaction. / Dierssen, Mara (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Gratacòs, Mònica (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Sahún, Ignasi (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Martín, Miguel (Universitat Pompeu Fabra. Àrea de Neurofarmacologia) ; Gallego, Xavier (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Amador-Arjona, Alehandro (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Martínez de Lagrán María (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Murtra, Patricia (Universitat Pompeu Fabra. Àrea de Neurofarmacologia) ; Martí, Eulalia (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Pujana, Miguel A. (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Ferrer, Isidre (Hospital Prínceps d’Espanya. Àrea de neuropatologia) ; Dalfo Capella, Esther (Universitat Autònoma de Barcelona. Departament de Biologia i Bioquímica Molecular) ; Martínez-Cué, Carmen (Universidad de Cantabria. Departamento de Psicologia y Farmacologia) ; Flórez, Jesús (Universidad de Cantabria. Departamento de Psicologia y Farmacologia) ; Torres-Peraza, Jesús F. (Universitat de Barcelona. Departament de Biologia Cel·lular i Anatomia Patològica) ; Alberch i Vié, Jordi (Universitat de Barcelona. Departament de Biologia Cel·lular i Anatomia Patològica) ; Maldonado, Rafael (Universitat Pompeu Fabra. Àrea de Neurofarmacologia) ; Fillat, Cristina (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center) ; Estivill, Xavier (Biomedical Research Park. Genes and Disease Program, Genomic Regulation Center)
Accumulating evidence has suggested that neurotrophins participate in the pathophysiology of mood disorders. We have developed transgenic mice overexpressing the full-length neurotrophin-3 receptor TrkC (TgNTRK3) in the central nervous system. [...]
2006 - 10.1016/j.nbd.2006.07.015
Neurobiology of disease, Vol. 24, Num. 2 (2006) , p. 403-18  
3.
12 p, 4.7 MB Dopaminergic and glutamatergic signaling crosstalk in Huntington’s disease neurodegeneration : the role of p25/cyclin-dependent kinase 5 / Paoletti, Paola (Institut d’Investigacions Biomèdiques August Pi i Sunyer) ; Vila, Ingrid (Institut d’Investigacions Biomèdiques August Pi i Sunyer) ; Rifé, Maria (Institut d’Investigacions Biomèdiques August Pi i Sunyer) ; Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Alberch i Vié, Jordi (Institut d’Investigacions Biomèdiques August Pi i Sunyer) ; Ginés, Silvia (Institut d’Investigacions Biomèdiques August Pi i Sunyer)
Altered glutamatergic and dopaminergic signaling has been proposed as contributing to the specific striatal cell death observed in Huntington’s disease (HD). However, the precise mechanisms by which mutant huntingtin sensitize striatal cells to dopamine and glutamate inputs remain unclear. [...]
2008 - 10.1523/JNEUROSCI.3237-08.2008
The Journal of neuroscience, Vol. 28 No. 40 (Oct. 2008) , p. 10090-10101  

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