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Articles, 1 records found
Articles 1 records found  
12 p, 192.3 KB Variation at FCGR2A and functionally related genes is associated with the response to anti-TNF therapy in rheumatoid arthritis / Avila-Pedretti, Gabriela (Vall d'Hebron Institut de Recerca) ; Tornero, Jesús (Hospital Universitario de Guadalajara) ; Fernández Nebro, Antonio (Instituto de Investigación Biomédica de Málaga) ; Blanco, Francisco (Instituto de Investigación Biomédica de A Coruña) ; González-Alvaro, Isidoro (Hospital Universitario de la Princesa (Madrid)) ; Cañete, Juan D. (Hospital Clínic de Barcelona) ; Maymó, Joan (Hospital del Mar (Barcelona, Catalunya)) ; Alperiz, Mercedes (Hospital Universitario Central de Asturias (Oviedo)) ; Fernández-Gutiérrez, Benjamín (Hospital Clínico San Carlos (Madrid)) ; Olivé Marqués, Alejandro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Corominas i Macias, Hèctor (Hospital de Sant Joan Despí Moisès Broggi) ; Erra, Alba (Hospital Sant Rafael (Barcelona)) ; Aterido, Adrià (Vall d'Hebron Institut de Recerca) ; López Lasanta, María (Vall d'Hebron Institut de Recerca) ; Tortosa, Raül (Vall d'Hebron Institut de Recerca) ; Julià Cano, Antoni (Vall d'Hebron Institut de Recerca) ; Marsal Barril, Sara (Vall d'Hebron Institut de Recerca)
Objective: Anti-TNF therapies have been highly efficacious in the management of rheumatoid arthritis (RA), but 25–30% of patients do not show a significant clinical response. There is increasing evidence that genetic variation at the Fc receptor FCGR2A is associated with the response to anti-TNF therapy. [...]
2015 - 10.1371/journal.pone.0122088
PloS one, Vol. 10, Núm. 4 (April 2015) , p. e0122088  

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