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13 p, 1.9 MB |
A study of differential microRNA expression profile in migraine : the microMIG exploratory study
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Gallardo, Víctor J.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gómez-Galván, J. B. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Asskour, L. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron) ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron) ;
Caronna, Edoardo (Hospital Universitari Vall d'Hebron) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Several studies have described potential microRNA (miRNA) biomarkers associated with migraine, but studies are scarcely reproducible primarily due to the heterogeneous variability of participants. Increasing evidence shows that disease-related intrinsic factors together with lifestyle (environmental factors), influence epigenetic mechanisms and in turn, diseases. [...]
2023 -  10.1186/s10194-023-01542-z
Journal of headache and pain, Vol. 24 (february 2023)
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12 p, 503.9 KB |
Excellent Response to OnabotulinumtoxinA : Different Definitions, Different Predictors
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Ornello, Raffaele (University of L'Aquila) ;
Baraldi, Carlo (AOU Policlinico di Modena) ;
Ahmed, Fayyaz (Hull University Teaching Hospitals) ;
Negro, Andrea (Sapienza University) ;
Miscio, Anna Maria (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ;
Santoro, Antonio (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Russo, Antonio (University of Campania "Luigi Vanvitelli") ;
Silvestro, Marcello (University of Campania "Luigi Vanvitelli") ;
Cevoli, Sabina (IRCCS Istituto delle Scienze Neurologiche di Bologna) ;
Brunelli, Nicoletta (Campus Bio-Medico University Hospital (Itàlia)) ;
Vernieri, Fabrizio (Campus Bio-Medico University Hospital (Itàlia)) ;
Grazzi, Licia (IRCCS Foundation "Carlo Besta" Neurological Institute) ;
Pani, Luca (VeraSci (Estats Units d'Amèrica)) ;
Andreou, Anna P (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ;
Lambru, Giorgio (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ;
Frattale, Ilaria (Tor Vergata University) ;
Kamm, Katharina (Ludwig Maximilians University München) ;
Ruscheweyh, Ruth (Ludwig Maximilians University München) ;
Russo, Marco (Azienda USL-IRCCS di Reggio Emilia) ;
Torelli, Paola (University of Parma) ;
Filatova, Elena (Sechenov First Moscow State Medical University) ;
Latysheva, Nina (Sechenov First Moscow State Medical University) ;
Gryglas-Dworak, Anna (Headache Center Wroclaw) ;
Straburzyński, Marcin (University of Warmia and Mazury) ;
Butera, Calogera (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Colombo, Bruno (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Filippi, Massimo (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martelletti, Paolo (Sapienza University) ;
Guerzoni, Simona (University of Modena and Reggio Emilia) ;
Sacco, Simona (University of L'Aquila) ;
Universitat Autònoma de Barcelona
The identification of patients who can benefit the most from the available preventive treatments is important in chronic migraine. We explored the rate of excellent responders to onabotulinumtoxinA in a multicenter European study and explored the predictors of such response, according to different definitions. [...]
2022 - 10.3390/ijerph191710975
International journal of environmental research and public health, Vol. 19 (september 2022)
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8 p, 761.9 KB |
MAB-MIG : registry of the spanish neurological society of erenumab for migraine prevention
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Belvís, Roberto (Institut d'Investigació Biomèdica Sant Pau) ;
Irimia, Pablo (Clínica Universidad de Navarra) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
González-Oria, Carmen (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cano, Antonio (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Viguera, Javier (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Sánchez, Belén (Hospital Quirónsalud Zaragoza) ;
Molina, Francisco (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Beltrán, Isabel (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Oterino, Agustín (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Cuadrado-Godia, Elisa (Hospital del Mar (Barcelona, Catalunya)) ;
Gómez-Camello, Angel (Hospital Universitario San Cecilio (Granada)) ;
Alberte-Woodward, Miguel (Hospital Universitario Lucus Augusti (Lugo)) ;
Jurado, Carmen (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Oms, Teresa (Hospital Dos de Maig) ;
Ezpeleta, David (Hospital Quironsalud Madrid) ;
de Terán, Javier Díaz (Hospital Universitario La Paz (Madrid)) ;
Morollón Sánchez-Mateos, Noemí (Hospital Universitari Dexeus (Barcelona, Catalunya)) ;
Latorre, Germán (Hospital Universitario de Fuenlabrada ( Madrid)) ;
Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lamas, Raquel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Toledano, Carlos (Clínica Universidad de Navarra) ;
Leira, Rogelio (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Santos, Sonia (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Del Rio, Margarita Sanchez (Clínica Universidad de Navarra) ;
Universitat Autònoma de Barcelona
Erenumab was approved in Europe for migraine prevention in patients with ≥ 4 monthly migraine days (MMDs). In Spain, Novartis started a personalized managed access program, which allowed free access to erenumab before official reimbursement. [...]
2021 - 10.1186/s10194-021-01267-x
Journal of headache and pain, Vol. 22 (july 2021)
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11 p, 1005.5 KB |
Cortical metabolic and structural differences in patients with chronic migraine. An exploratory 18 FDG-PET and MRI study
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Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pareto, Deborah (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gallardo, Víctor J.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cuberas-Borrós, Gemma (Hospital Universitari Vall d'Hebron) ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Caronna, Edoardo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vila-Balló, Adrià (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lorenzo-Bosquet, Carles (Hospital Universitari Vall d'Hebron) ;
Castell-Conesa, Joan (Hospital Universitari Vall d'Hebron) ;
Rovira, Alex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
To describe interictal brain structural and metabolic differences between patients with episodic migraine (EM), chronic migraine (CM) and healthy controls (HC). This is an exploratory study including right-handed age-matched women with EM, CM and HC. [...]
2021 - 10.1186/s10194-021-01289-5
Journal of headache and pain, Vol. 22 (july 2021)
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10 p, 1.9 MB |
InterMiG : international differences in the therapeutic approach to migraine patients in specialized headache centers
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Gago-Veiga, Ana Beatriz (Instituto de Investigación Hospital Universitario de la Princesa) ;
Huhn, J-I (Praxis Gendolla) ;
Latysheva, Nina (I.M.Sechenov First Moscow State Medical University) ;
Vieira Campos, A. (Instituto de Investigación Hospital Universitario de la Princesa) ;
Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sacco, Simona (University of L'Aquila) ;
Frattale, Ilaria (University of L'Aquila) ;
Ornello, R. (University of L'Aquila) ;
Ruscheweyh, Ruth (Ludwig Maximilians University Munich) ;
Marques, I. B. (Hospital da Luz (Lisboa, Portugal)) ;
Gryglas-Dworak, A. (Private Headache Clinic (Polònia)) ;
Stark, C. (Austin Health) ;
Gallardo, Víctor J.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
There is currently a wide therapeutic arsenal for migraine patients, without a single first-line preventive drug and we choose the different available alternatives taking into account comorbidities, national guidelines, previous treatments and personal experiences. [...]
2021 - 10.1186/s10194-021-01258-y
Journal of headache and pain, Vol. 22 (may 2021)
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2 p, 593.4 KB |
La perspectiva del pacient com a criteri mèdic de la migranya
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Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gallardo, Víctor J.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Caronna, Edoardo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Els resultats reportats pels pacients (PROs) son eines mèdiques de quantificació de discapacitat i impacte sobre la seva qualitat de vida, aplicables a la migranya. En una avaluació diària en la qual hi constaven la freqüència de la migranya, la intensitat del dolor, el consum d'analgèsics i diferents qüestionaris PROs abans i després del tractament, investigadors de l'Hospital Universitari i l'Institut de Recerca Vall d'Hebron i del Departament de Medicina de la UAB han conclòs que l'avaluació dels PROs als 3 mesos de tractament és un punt crucial per contrastar l'eficàcia i la tolerabilitat dels fàrmacs. [...]
Los resultados reportados por los pacientes (PROs) son herramientas médicas de cuantificación de discapacidad e impacto sobre su calidad de vida, aplicables a la migraña. En una evaluación diaria en la que constaban la frecuencia de la migraña, la intensidad del dolor, el consumo de analgésicos y diferentes cuestionarios PROs antes y después del tratamiento, investigadores del Hospital Universitario y del Institut de Recerca Vall d'hebron y del Departamento de Medicina de la UAB han concluido que la evaluación de los PROs a los 3 meses del tratamiento es crucial para contrastar la eficacia y la tolerabilidad de los fármacos. [...]
The Patient-reported Outcomes (PROs) are tools used in medicine to quantify the disability and impact on the patient's quality of life, applicable in migraine. In a daily evaluation of the migraine frequency, the pain intensity, the analgesic consumption, and different PROs questionnaires (MSG and PGI-C) before and after the treatment, researchers from the University Hospital and Research Institute Vall d'Hebron and the UAB's Department of Medicine have concluded that the PROs evaluation after three months of treatment is crucial to contrast the drug's efficiency and tolerability. [...]
2022
UAB divulga, Febrer 2022
3 documentos
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14 p, 810.0 KB |
Is There a Gender Difference in the Response to onabotulinumtoxinA in Chronic Migraine? Insights from a Real-Life European Multicenter Study on 2879 Patients
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Ornello, Raffaele (University of L'Aquila. Department of Applied Clinical Sciences and Biotechnology) ;
Ahmed, Fayyaz (Hull University Teaching Hospitals. Department of Neurosciences) ;
Negro, Andrea (Sapienza University. Department of Clinical and Molecular Medicine) ;
Miscio, Anna Maria (Fondazione IRCCS "Casa Sollievo della Sofferenza". Unit of Neurology) ;
Santoro, Antonio (Fondazione IRCCS "Casa Sollievo della Sofferenza". Unit of Neurology) ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Russo, Antonio (University of Campania "Luigi Vanvitelli". Department of Medical, Surgical, Neurological, Metabolic, and Aging Sciences) ;
Silvestro, Marcello (University of Campania "Luigi Vanvitelli". Department of Medical, Surgical, Neurological, Metabolic, and Aging Sciences) ;
Cevoli, Sabina (IRCCS Istituto delle scienze Neurologiche di Bologna) ;
Brunelli, Nicoletta (Campus Bio-Medico University Hospital. Headache and Neurosonology Unit) ;
Vernieri, Fabrizio (Campus Bio-Medico University Hospital. Headache and Neurosonology Unit) ;
Grazzi, Licia (IRCCS Foundation "Carlo Besta" Neurological Institute. Neurology Department) ;
Baraldi, Carlo (University of Modena and Reggio Emilia. Department of Biomedical, Metabolic and Neural Sciences) ;
Guerzoni, Simona (University of Modena and Reggio Emilia. Department of Biomedical, Metabolic and Neural Sciences) ;
Andreou, Anna P. (Guy's and St Thomas' NHS Foundation Trust. Headache Service) ;
Lambru, Giorgio (Guy's and St Thomas' NHS Foundation Trust. Headache Service) ;
Kamm, Katharina (Ludwig Maximilians University München. Department of Neurology) ;
Ruscheweyh, Ruth (Ludwig Maximilians University München. Department of Neurology) ;
Russo, Marco (Azienda USL-IRCCS di Reggio Emilia. Neuromotor and Rehabilitation Department) ;
Torelli, Paola (University of Parma. Headache Center) ;
Filatova, Elena (Sechenov First Moscow State Medical University (Sechenov University). Department of Neurology) ;
Latysheva, Nina (Sechenov First Moscow State Medical University (Sechenov University). Department of Neurology) ;
Gryglas-Dworak, Anna (Headache Center Wroclaw) ;
Straburzyński, Marcin (Headache Clinic (Warsaw, Poland)) ;
Butera, Calogera (IRCCS San Raffaele Scientific Institute. Neurophysiology Service) ;
Colombo, Bruno (IRCCS San Raffaele Scientific Institute (Milà, Itàlia). Neurology Unit) ;
Filippi, Massimo (IRCCS San Raffaele Scientific Institute. Neurorehabilitation Unit) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martelletti, Paolo (Sapienza University. Department of Clinical and Molecular Medicine) ;
Sacco, Simona (University of L'Aquila. Department of Applied Clinical Sciences and Biotechnology) ;
Universitat Autònoma de Barcelona
Migraine is mostly a female disorder because of its lower prevalence in men. Less than 20% of patients included in the available studies on migraine treatments are men; hence, the evidence on migraine treatments might not apply to men. [...]
2021 - 10.1007/s40122-021-00328-y
Pain and Therapy, Vol. 10 (september 2021) , p. 1605-1618
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14 p, 826.8 KB |
Early Management of OnabotulinumtoxinA Treatment in Chronic Migraine : Insights from a Real-Life European Multicenter Study
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Ornello, Raffaele (University of L'Aquila. Neuroscience Section, Department of Applied Clinical Sciences and Biotechnology) ;
Ahmed, Fayyaz (Hull University Teaching Hospitals) ;
Negro, Andrea (Sapienza University) ;
Miscio, Anna Maria (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ;
Santoro, Antonio (Fondazione IRCCS "Casa Sollievo Della Sofferenza") ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Russo, Antonio (University of Campania "Luigi Vanvitelli") ;
Silvestro, Marcello (University of Campania "Luigi Vanvitelli".) ;
Cevoli, Sabina (IRCCS Istituto Delle Scienze Neurologiche Di Bologna) ;
Brunelli, Nicoletta (Campus Bio-Medico University Hospital) ;
Vernieri, Fabrizio (Campus Bio-Medico University Hospital) ;
Grazzi, Licia (IRCCS Foundation "Carlo Besta" Neurological Institute) ;
Baraldi, Carlo (University of Modena and Reggio Emilia) ;
Guerzoni, Simona (University of Modena and Reggio Emilia) ;
Andreou, Anna P. (Guy's and St Thomas' NHS Foundation Trust) ;
Lambru, Giorgio (Guy's and St Thomas' NHS Foundation Trust) ;
Frattale, Ilaria (Tor Vergata University) ;
Kamm, Katharina (Ludwig Maximilians University München) ;
Ruscheweyh, Ruth (Ludwig Maximilians University München) ;
Russo, Marco (Azienda USL-IRCCS Di Reggio Emilia) ;
Torelli, Paola (University of Parma) ;
Filatova, Elena (Sechenov First Moscow State Medical University) ;
Latysheva, Nina (Sechenov First Moscow State Medical University) ;
Gryglas-Dworak, Anna (Headache Center Wroclaw) ;
Straburzynski, Marcin (Terapia Neurologiczna Samodzielni) ;
Butera, Calogera (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Colombo, Bruno (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Filippi, Massimo (IRCCS San Raffaele Scientific Institute (Milà, Itàlia)) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martelletti, Paolo (Sapienza University'Andrea) ;
Sacco, Simona (University of L'Aquila) ;
Universitat Autònoma de Barcelona
OnabotulinumtoxinA (BT-A) quarterly was the first treatment approved specifically for chronic migraine (CM). It is unclear whether three cycles are better than two to assess early BT-A response. We performed a retrospective analysis on real-life prospectively collected data in 16 European headache centers. [...]
2021 - 10.1007/s40122-021-00253-0
Pain and Therapy, Vol. 10 (march 2021) , p. 637-650
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12 p, 641.2 KB |
Headache : A striking prodromal and persistent symptom, predictive of COVID-19 clinical evolution
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Caronna, Edoardo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ballvé, Alejandro (Hospital Universitari Vall d'Hebron) ;
Llaurado, Arnau (Hospital Universitari Vall d'Hebron) ;
Gallardo, Víctor J.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ariton, Diana María (Hospital Universitari Vall d'Hebron) ;
Lallana, Sofia (Hospital Universitari Vall d'Hebron) ;
López Maza, Samuel (Hospital Universitari Vall d'Hebron) ;
Olivé-Gadea, Marta (Hospital Universitari Vall d'Hebron) ;
Quibus, Laura (Hospital Universitari Vall d'Hebron) ;
Restrepo, Juan Luis (Hospital Universitari Vall d'Hebron) ;
Rodrigo-Gisbert, Marc (Hospital Universitari Vall d'Hebron) ;
Vilaseca, Andreu (Hospital Universitari Vall d'Hebron) ;
Hernandez Gonzalez, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martinez Gallo, Monica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alpuente, Alicia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Torres-Ferrús, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pujol Borrell, Ricard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Álvarez Sabín, José (Hospital Universitari Vall d'Hebron) ;
Pozo-Rosich, Patricia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
To define headache characteristics and evolution in relation to COVID-19 and its inflammatory response. This is a prospective study, comparing clinical data and inflammatory biomarkers of COVID-19 patients with and without headache, recruited at the Emergency Room. [...]
2020 - 10.1177/0333102420965157
Cephalalgia, Vol. 40 (november 2020) , p. 1410-1421
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