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19 p, 7.4 MB |
Rp11-362k2.2:Rp11-767i20.1 genetic variation is associated with post-reperfusion therapy parenchymal hematoma. a gwas meta-analysis
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Muiño, Elena (Institut d'Investigació Biomèdica Sant Pau) ;
Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ;
Carrera, C. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Llucià-Carol, Laia (Institut d'Investigació Biomèdica Sant Pau) ;
Gallego-Fabrega, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Cullell, N. (Fundació MútuaTerrassa per la Docència i la Recerca) ;
Lledós, Miquel (Institut d'Investigació Biomèdica Sant Pau) ;
Castillo, J. (Clinical Neurosciences Research Laboratories. Health Research Institute of Santiago de Compostela (IDIS)) ;
Sobrino, T. (Clinical Neurosciences Research Laboratories. Health Research Institute of Santiago de Compostela (IDIS)) ;
Campos, Francisco (Clinical Neurosciences Research Laboratories. Health Research Institute of Santiago de Compostela (IDIS)) ;
Rodríguez-Castro, E. (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Millán, M. (Institut Germans Trias i Pujol) ;
Muñoz-Narbona, L. (Institut Germans Trias i Pujol) ;
Bustamante, Alejandro (Institut Germans Trias i Pujol) ;
López-Cancio, E. (Hospital Universitario Central de Asturias) ;
Ribó, M. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Álvarez-Sabin, José (Hospital Universitari Vall d'Hebron) ;
Jiménez-Conde, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Roquer, J. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Giralt Steinhauer, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Soriano-Tárraga, C. (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Vives-Bauza, C. (Instituto de Investigación Sanitaria de Palma) ;
Díaz Navarro, R. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Tur, S. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Obach, V. (Hospital Clínic i Provincial de Barcelona) ;
Arenillas, Juan F.. (Hospital Clínico Universitario de Valladolid) ;
Segura, T. (Complejo Hospitalario Universitario de Albacete) ;
Serrano-Heras, G. (Complejo Hospitalario Universitario de Albacete) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Delgado Mederos, Raquel (Institut d'Investigació Biomèdica Sant Pau) ;
Camps-Renom, Pol (Institut d'Investigació Biomèdica Sant Pau) ;
Prats-Sánchez, Luis Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Guisado-Alonso, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Guasch, Marina (Institut d'Investigació Biomèdica Sant Pau) ;
Marin, Rebeca (Institut d'Investigació Biomèdica Sant Pau) ;
Martínez-Domeño, Alejandro (Institut d'Investigació Biomèdica Sant Pau) ;
Freijo-Guerrero, M.D.M. (Instituto de Investigación Sanitaria Biocruces Bizkaia) ;
Moniche, F. (Instituto de Biomedicina de Sevilla) ;
Cabezas, Juan Antonio (Instituto de Biomedicina de Sevilla) ;
Castellanos, M. (Complejo Hospitalario Universitario de A Coruña) ;
Krupinsky, J. (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Strbian, D. (Helsinki University Hospital (Finlàndia)) ;
Tatlisumak, T. (Sahlgrenska University Hospital (Suècia)) ;
Thijs, V. (Austin Health. Department of Neurology) ;
Lemmens, R. (University Hospitals Leuven (Bèlgica)) ;
Slowik, A. (Jagiellonian University Medical College) ;
Pera, J. (Jagiellonian University Medical College) ;
Heitsch, Laura (Washington University School of Medicine) ;
Ibañez, L. (Washington University School of Medicine) ;
Cruchaga, Carlos (Washington University School of Medicine) ;
Dhar, R. (Washington University School of Medicine) ;
Lee, J.M. (Washington University School of Medicine) ;
Montaner, J. (Instituto de Biomedicina de Sevilla) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Stroke is one of the most common causes of death and disability. Reperfusion therapies are the only treatment available during the acute phase of stroke. Due to recent clinical trials, these therapies may increase their frequency of use by extending the time-window administration, which may lead to an increase in complications such as hemorrhagic transformation, with parenchymal hematoma (PH) being the more severe subtype, associated with higher mortality and disability rates. [...]
2021 -  10.3390/jcm10143137
Journal of clinical medicine, Vol. 10 Núm. 14 (february 2021) , p. 3137
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10 p, 736.9 KB |
Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage : a systematic review and meta-analysis of individual patient data
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Al-Shahi Salman, Rustam (Centre for Clinical Brain Sciences. University of Edinburgh) ;
Frantzias, Joseph (King's College Hospital NHS Foundation Trust) ;
Lee, Robert J. (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK) ;
Lyden, Patrick D. (Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA) ;
Battey, Thomas W. K. (Massachusetts General Hospital (Boston)) ;
Ayres, Alison M. (Massachusetts General Hospital (Boston)) ;
Goldstein, Joshua N. (Massachusetts General Hospital (Boston)) ;
Mayer, Stephan A. (Department of Neurology, Henry Ford Health System, Detroit, MI, USA) ;
Steiner, Thorsten (Heidelberg University Hospital (Alemanya)) ;
Wang, Xia (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ;
Arima, Hisatomi (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ;
Hasegawa, Hitoshi (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ;
Oishi, Makoto (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ;
Godoy, Daniel A. (Intensive Care Unit, Hospital Interzonal de Agudos "San Juan Bautista", Catamarca, Argentina) ;
Masotti, Luca (Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy) ;
Dowlatshahi, Dar (Department of Medicine (Neurology), University of Ottawa and Ottawa Hospital Research Institute, Ottawa, ON, Canada) ;
Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jang, Dong-Kyu (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Castillo, José (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Yao, Xiaoying (Department of Neurology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China) ;
Claassen, Jan (Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ;
Volbers, Bastian (Bern University Hospital) ;
Kazui, Seiji (Kazui Medical Office, Ikeda, Osaka, Japan) ;
Okada, Yasushi (Department of Cerebrovascular Medicine and Neurology, National Hospital Organisation Kyushu Medical Centre, Fukuoka, Japan) ;
Fujimoto, Shigeru (Division of Neurology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan) ;
Toyoda, Kazunori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ;
Li, Qi (Department of Neurology, ThE First Affiliated Hospital of Chongqing Medical University, Chongqing, China) ;
Khoury, Jane (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Álvarez Sabín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hernández-Guillamon, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Prats-Sánchez, Luis Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Cai, Chunyan (Centre for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, USA) ;
Kate, Mahesh P. (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ;
McCourt, Rebecca (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ;
Venkatasubramanian, Chitra (Division of Stroke and Neurocritical Care, Stanford University, Palo Alto, CA, USA) ;
Diringer, Michael N. (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ;
Ikeda, Yukio (Department of Neurosurgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan) ;
Worthmann, Hans (Department of Neurology, Hannover Medical School, Hannover, Germany) ;
Ziai, Wendy C. (Johns Hopkins University School of Medicine, Department of Neurology, Anaesthesia and Critical Care Medicine, Division of Neurocritical Care, Baltimore, MD, USA) ;
d'Esterre, Christopher D. (Department of Radiology, Foothills Medical Centre, University of Calgary, Calgary, AB, Canada) ;
Aviv, Richard I (Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada) ;
Raab, Peter (Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany) ;
Murai, Yasuo (Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan) ;
Zazulia, Allyson R. (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ;
Butcher, Kenneth S. (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ;
Seyedsaadat, Seyed Mohammad (Department of Radiology, Mayo Clinic, Rochester, MN, USA) ;
Grotta, James C. (Memorial Hermann Hospital (Houston, Estats Units d'Amèrica)) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Broderick, Joseph P (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ;
Yamamoto, Haruko (Center for Advanced Clinical and Translational Sciences, National Cerebral and Cerebrovascular Center, Suita, Osaka, Japan) ;
Staykov, Dimitre (Department of Neurology, Hospital of the Brothers of St John, Eisenstadt, Austria) ;
Connolly, E. Sander (Department of Neurosurgery, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ;
Selim, Magdy (Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA) ;
Leira, Rogelio (Complejo Hospitalario Universitario de Santiago de Compostela) ;
Moon, Byung Hoo (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ;
Demchuk, Andrew (Department of Clinical Neurosciences and Department of Radiology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada) ;
Di Napoli, Mario (Neurological Service, San Camillo de'Lellis General Hospital, Rieti, Italy) ;
Fujii, Yukihiko (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ;
Anderson, Craig S.. (The George Institute for Global Health, China at Peking University Health Science Center, Beijing, China) ;
Rosand, Jonathan (Massachusetts General Hospital (Boston)) ;
Universitat Autònoma de Barcelona
Intracerebral haemorrhage growth is associated with poor clinical outcome and is a therapeutic target for improving outcome. We aimed to determine the absolute risk and predictors of intracerebral haemorrhage growth, develop and validate prediction models, and evaluate the added value of CT angiography. [...]
2018 - 10.1016/S1474-4422(18)30253-9
The Lancet neurology, Vol. 17 (october 2018) , p. 885-894
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15 p, 517.3 KB |
GRECOS project (Genotyping Recurrence Risk of Stroke). The use of genetics to predict the vascular recurrence after stroke
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Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron) ;
Mendióroz, Maite (Hospital Universitari Vall d'Hebron) ;
Giralt, Dolors (Hospital Universitari Vall d'Hebron) ;
Nafría, Cristina (Hospital Universitari Vall d'Hebron) ;
Garcia, Elena (Fundació Docència i Recerca Mútua Terrassa) ;
Carrera, Caty (Hospital Universitari Vall d'Hebron) ;
Gallego-Fabrega, Cristina (Fundació Docència i Recerca Mútua Terrassa) ;
Domingues-Montanari, Sophie (Hospital Universitari Vall d'Hebron) ;
Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron) ;
Ribo, Marc (Hospital Universitari Vall d'Hebron) ;
Castellanos, Mar (Hospital Universitari de Girona Doctor Josep Trueta) ;
Martínez, Sergi (Institut d'Investigació Biomèdica Sant Pau) ;
Freijo, Mari Mar (Hospital de Basurto (Bilbao, Biscaia)) ;
Jiménez-Conde, Jordi (Hospital del Mar (Barcelona, Catalunya)) ;
Rubiera, Marta (Hospital Universitari Vall d'Hebron) ;
Álvarez-Sabin, José (Hospital Universitari Vall d'Hebron) ;
Molina, Carlos A. (Hospital Universitari Vall d'Hebron) ;
Font, Maria Angels (Hospital Universitari de Bellvitge) ;
Grau Olivares, Marta (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Palomeras, Ernest (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Pérez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martinez Zabaleta, Maite (Hospital Universitario de Donostia (Sant Sebastià, País Basc)) ;
Masjuan, Jaime (Hospital Universitario Ramón y Cajal (Madrid)) ;
Moniche, Francisco (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cánovas, David (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Piñana, Carlos (Hospital Universitario Virgen de las Nieves (Granada)) ;
Purroy, Francisco (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Cocho, Dolores (Hospital General de Granollers) ;
Navas, Inma (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Tejero, Carlos (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Aymerich, Nuria (Complejo Hospitalario de Navarra) ;
Cullell, Natalia (Fundació Docència i Recerca Mútua Terrassa) ;
Muiño, Elena (Fundació Docència i Recerca Mútua Terrassa) ;
Serena, Joaquín (Hospital Universitari de Girona Doctor Josep Trueta) ;
Rubio, Francisco (Hospital Universitari de Bellvitge) ;
Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roquer González, Jaume (Hospital del Mar (Barcelona, Catalunya)) ;
Arenillas, Juan F.. (Hospital Clínico Universitario de Valladolid) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Keene, Keith (Center for Health Disparities. East Carolina University) ;
Chen, Wei-Min (University of Virginia) ;
Worrall, Bradford (University of Virginia) ;
Sale, Michele (Center for Public Health Genomics, University of Virginia) ;
Arboix, Adrià (Hospital del Sagrat Cor (Barcelona, Catalunya)) ;
Krupinski, Jerzy (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Montaner, Joan (Hospital Universitari Vall d'Hebron) ;
GRECOSstudy group ;
Universitat Autònoma de Barcelona
Background and Purpose-Vascular recurrence occurs in 11% of patients during the first year after ischemic stroke (IS) or transient ischemic attack (TIA). Clinical scores do not predict the whole vascular recurrence risk, therefore we aimed to find genetic variants associated with recurrence that might improve the clinical predictive mode is in IS. [...]
2017 - 10.1161/STROKEAHA.116.014322
Stroke, Vol. 48 Núm. 5 (2017) , p. 1147-1153
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