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1.
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33 p, 4.3 MB |
Ascitic fluid regulates the local innate immune response of patients with cirrhosis
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Nieto Sáchica, Juan Camilo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Perea, Lidia (Institut d'Investigació Biomèdica Sant Pau) ;
Soriano, German (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Zamora, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Cantó, Elisabet (Institut d'Investigació Biomèdica Sant Pau) ;
Medina Dols, Aina (Institut d'Investigació Biomèdica Sant Pau) ;
Poca Pastor, María Antonia (Hospital Universitari Vall d'Hebron) ;
Sánchez, Elisabet (Instituto de Salud Carlos III) ;
Roman, Eva (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Julià, Germà (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Navarro Risueño, Ferran (Institut d'Investigació Biomèdica Sant Pau) ;
Gely, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Guarner-Argente, Carlos (Institut d'Investigació Biomèdica Sant Pau) ;
Juarez, Candido (Institut d'Investigació Biomèdica Sant Pau) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau)
Ascitic neutrophils from cirrhotic patients with spontaneous bacterial peritonitis (SBP) exhibit an impaired oxidative burst that could facilitate bacterial infection. However, the influence of the cell-free ascitic fluid of these patients on neutrophil function has not been investigated. [...]
2018 -  10.1002/JLB.3A0218-072R
Journal of Leukocyte Biology, Vol. 104, Issue 4 (October 2018) , p. 833-841
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2.
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11 p, 767.6 KB |
Rebleeding and mortality risk are increased by ACLF but reduced by pre-emptive TIPS
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Trebicka, Jonel (Institut de Bioenginyeria de Catalunya) ;
Gu, Wenyi (Shanghai Jiao Tong University) ;
Ibáñez-Samaniego, Luis (Hospital General Universitario Gregorio Marañón) ;
Hernández-Gea, Virginia (Centro de Investigación Biomédica Red de enfermedades hepáticas y digestivas (CIBERehd)) ;
Pitarch, Carla (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
García López, Elisabet (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
Procopet, Bogdan ("Iuliu Hatieganu" University of Medicine and Pharmacy) ;
Giráldez-Gallego, Álvaro (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Amitrano, Lucio (Ospedale A Cardarelli) ;
Villanueva, Càndid (Institut d'Investigació Biomèdica Sant Pau) ;
Thabut, Dominique (Paris Sorbonne Université) ;
Silva-Junior, Gilberto (Hospital Clínic i Provincial de Barcelona) ;
Martinez, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Genescà Ferrer, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bureau, Cristophe (University Paul Sabatier of Toulouse) ;
Llop, Elba (Universidad Autónoma de Madrid) ;
Laleman, Wim (University Hospitals Leuven (Bèlgica)) ;
Palazon, Jose Maria (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Castellote, Jose (Hospital Universitari de Bellvitge) ;
Rodrigues, Susana G. (Centro Hospitalar São João) ;
Gluud, Lise Lotte (University of Copenhagen) ;
Ferreira, Carlos Noronha (Hospital de Santa Maria - Centro Hospitalar Lisboa Norte) ;
Barcelo, Rafael (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cañete Hidalgo, Nuria (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rodriguez, Manuel (Hospital Universitario Central de Asturias) ;
Ferlitsch, Arnulf (Medical University of Vienna) ;
Mundi Sánchez-Ramade, Jose Luis (Hospital Universitario San Cecilio (Granada)) ;
Gronbaek, Henning (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Hernandez-Guerra, Manuel (Hospital Universitario de Canarias (La Laguna)) ;
Sassatelli, Romano (Arcispedale Santa Maria Nuova-IRCCS) ;
Dell'Era, Alessandra (University of the Studies of Milan) ;
Senzolo, Marco (University Hospital of Padova (Pàdua, Itàlia)) ;
Abraldes, Juan G. (University of Alberta) ;
Romero-Gómez, Manuel (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Zipprich, Alexander (Martin Luther University Halle-Wittenberg) ;
Casas, Meritxell (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Masnou, Helena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Primignani, Massimo (CRC "A.M.and A.Miglaivacca" Center for Liver Disease) ;
Weiss, Emmanuel (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
Catalina, María-Vega (Hospital General Universitario Gregorio Marañón) ;
Erasmus, Hans Peter (University of Frankfurt) ;
Uschner, Frank Erhard (University of Frankfurt) ;
Schulz, Martin (University of Frankfurt) ;
Brol, Maximilian Joseph (University of Bonn) ;
Praktiknjo, Michael (University of Bonn) ;
Chang, Johannes (University of Bonn) ;
Krag, Aleksander (Odense University Hospital (Dinamarca)) ;
Nevens, Frederik (University Hospitals Leuven (Bèlgica)) ;
Calleja, Jose Luis (Universidad Autónoma de Madrid) ;
Robic, Marie Angèle (University Paul Sabatier of Toulouse) ;
Conejo, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Albillos, Agustín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Rudler, Marika (Paris Sorbonne Université) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Guardascione, Maria Anna (Ospedale A Cardarelli) ;
Tantau, Marcel ("Iuliu Hatieganu" University of Medicine and Pharmacy) ;
Bosch, Jaime (Bern University) ;
Torres, Ferran (Hospital Clínic i Provincial de Barcelona) ;
Pavesi, Marco (European Foundation for the Study of Chronic Liver Failure - EF CLIF) ;
García-Pagán, JC (Centro de Investigación Biomédica Red de enfermedades hepáticas y digestivas (CIBERehd)) ;
Jansen, Christian (University of Bonn) ;
Bañares, Rafael (Universidad Complutense de Madrid) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
The relationship between acute-on-chronic liver failure (ACLF) and acute variceal bleeding (AVB) is poorly understood. Specifically, the prevalence and prognosis of ACLF in the context of AVB is unclear, while the role of transjugular intrahepatic portosystemic shunt (TIPS) in the management in patients with ACLF has not been described to date. [...]
2020 - 10.1016/j.jhep.2020.04.024
Journal of Hepatology, Vol. 73 Núm. 5 (november 2020) , p. 1082-1091
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3.
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14 p, 1.0 MB |
The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology
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Trebicka, Jonel (JW Goethe University Hospital) ;
Fernández, Javier (Hospital Clínic i Provincial de Barcelona) ;
Papp, Maria (University of Debrecen) ;
Caraceni, Paolo (University of Bologna) ;
Laleman, Wim (University of Leuven) ;
Gambino, Carmine (University of Padova) ;
Giovo, Ilaria (University of Torino) ;
Uschner, Frank Erhard (JW Goethe University Hospital) ;
Jiménez, Cesar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mookerjee, Rajeshwar Prosad (UCL Royal Free Hospital) ;
Gustot, Thierry (Universite Libre de Bruxelles) ;
Albillos, Agustín (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Bañares, Rafael (Universidad Complutense de Madrid) ;
Janicko, Martin (Pavol Jozef Safarik University in Kosice) ;
Steib, Christian (University Hospital Munich) ;
Reiberger, Thomas (Medical University of Vienna) ;
Acevedo, Juan (University Hospitals Plymouth NHS Trust (Regne Unit)) ;
Gatti, Pietro (Internal Medicine PO Ostuni. ASL Brindisi) ;
Bernal, William (King's College Hospital NHS Foundation Trust) ;
Zeuzem, Stefan (JW Goethe University Hospital) ;
Zipprich, Alexander (University Hospital Halle-Wittenberg) ;
Piano, Salvatore (University of Padova) ;
Berg, Thomas (Leipzig University) ;
Bruns, Tony (Aachen University Hospital) ;
Bendtsen, Flemming (Hvidovre University Hospital) ;
Coenraad, Minneke (Leiden University Medical Center) ;
Merli, Manuela (Universitá Sapienza Roma) ;
Stauber, Rudolf (Medical University of Graz) ;
Zoller, Heinz (Medical University of Innsbruck) ;
Presa Ramos, José (CHTMAD Vila Real) ;
Solé, Cristina (Hospital Clínic i Provincial de Barcelona) ;
Soriano, German (Institut d'Investigació Biomèdica Sant Pau) ;
De Gottardi, Andrea (Universita della Svizzera Italiana) ;
Gronbaek, Henning (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Saliba, Faouzi (AP-HP Hôpital Paul Brousse) ;
Trautwein, Christian (Aachen University Hospital) ;
Özdogan, Osman Cavit (Marmara University) ;
Francque, Sven (University Hospital Antwerp) ;
Ryder, Stephen David (University of Nottingham) ;
Nahon, Pierre (AP-HP. Hôpital Jean Verdier) ;
Romero-Gómez, Manuel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Van Vlierberghe, Hans (Universitair Ziekenhuis Gent) ;
Francoz, Claire (Université de Paris) ;
Manns, Michael (Hannover Medical School) ;
García López, Elisabet (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Tufoni, Manuel (University of Bologna) ;
Amoros, Alex (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Pavesi, Marco (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Sanchez, Cristina (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Curto, Anna (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Pitarch, Carla (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Putignano, Antonella (Universite Libre de Bruxelles) ;
Moreno, Esau (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Shawcross, Debbie (King's College Hospital NHS Foundation Trust) ;
Aguilar, Ferran (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Clària, J (Hospital Clínic i Provincial de Barcelona) ;
Ponzo, Paola (University of Torino) ;
Jansen, Christian (University Hospital Bonn (Bonn, Alemanya)) ;
Vitalis, Zsuzsanna (University of Debrecen) ;
Zaccherini, Giacomo (University of Bologna) ;
Balogh, Boglarka (University of Debrecen) ;
Vargas Blasco, Víctor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Montagnese, Sara (University of Padova) ;
Alessandria, Carlo (University of Torino) ;
Bernardi, Mauro (University of Bologna) ;
Ginès, Pere (Hospital Clínic i Provincial de Barcelona) ;
Jalan, Rajiv (UCL Medical School. Royal Free Hospital) ;
Moreau, Richard (Université de Paris) ;
Angeli, Paolo (University of Padova) ;
Arroyo, Vicente (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Maschmeier, Miriam (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Semela, David (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Elkrief, Laure (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Elsharkawy, Ahmed (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Tornai, Tamás (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Tornai, Istvan (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Altorjay, Istvan (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Antognoli, Agnese (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Baldassarre, Maurizio (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Gagliardi, Martina (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Bertoli, Eleonora (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Mareso, Sara (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Brocca, Alessandra (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Campion, Daniela (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Saracco, Giorgio Maria (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Rizzo, Martina (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Lehmann, Jennifer (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Pohlmann, Alessandra (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Praktiknjo, Michael (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Schierwagen, Robert (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Solà, Elsa (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Amari, Nesrine (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Rodriguez, Miguel (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Nevens, Frederik (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Clemente, Ana (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Jarcuska, Peter (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Gerbes, Alexander L. (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Mandorfer, Mattias (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Welsch, Christoph (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Ciraci, Emanuela (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Patel, Vish (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Ripoll, Cristina (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Herber, Adam (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Horn, Paul (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Danielsen, Karen Vagner (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Gluud, Lise Lotte (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Schaapman, Jelte (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Riggio, Oliviero (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Rainer, Florian (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Moritz, Jörg Tobiasch (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Mesquita, Mónica (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Akpata, Osagie (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Lykke Eriksen, Peter (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Samuel, Didier (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Tresson, Sylvie (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Strnad, Pavel (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Amathieu, Roland (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Simón-Talero, Macarena (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Smits, Francois (PREDICT STUDY group of the EASL-CLIF Consortium) ;
van den Ende, Natalie (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Martinez, Javier (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Garcia, Rita (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Markwardt, Daniel (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Rupprechter, Harald (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Engelmann, Cornelius (PREDICT STUDY group of the EASL-CLIF Consortium) ;
Universitat Autònoma de Barcelona
Acute decompensation (AD) of cirrhosis is defined as the acute development of ascites, gastrointestinal hemorrhage, hepatic encephalopathy, infection or any combination thereof, requiring hospitalization. [...]
2020 - 10.1016/j.jhep.2020.06.013
Journal of Hepatology, Vol. 73 Núm. 4 (october 2020) , p. 842-854
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11 p, 519.8 KB |
Prevalence and clinical impact of alcohol withdrawal syndrome in alcohol-associated hepatitis and the potential role of prophylaxis : a multinational, retrospective cohort study
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Marti-Aguado, David (Institut d'Investigació Biomèdica (INCLIVA)) ;
Gougol, Amir (University of California) ;
Gomez-Medina, Concepcion (Institut d'Investigació Biomèdica (INCLIVA)) ;
Jamali, Arsia (University of Pittsburgh Medical Center) ;
Abo-Zed, Abdelrhman (University of Pittsburgh Medical Center) ;
Morales-Arraez, Dalia (Hospital Universitario de Canarias (La Laguna)) ;
Jimenez-Sosa, Alejandro (Hospital Universitario de Canarias (La Laguna)) ;
Burns, Keith (University of Pittsburgh Medical Center) ;
Bawa, Aditi (University of Pittsburgh Medical Center) ;
Hernández, Anjara (Hospital Universitario de Canarias (La Laguna)) ;
Pujol, Claudia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Szafranska, Justyna (Institut d'Investigació Biomèdica Sant Pau) ;
Chiu, Wai Kan (University of Pittsburgh Medical Center) ;
Villagrasa, Ares (Hospital Universitari Vall d'Hebron) ;
Ventura-Cots, Meritxell (Hospital Universitari Vall d'Hebron) ;
Gandicheruvu, Haritha (University of Pittsburgh Medical Center) ;
Lluch, Paloma (Institut d'Investigació Biomèdica (INCLIVA)) ;
Chen, Hui-Wei (Allegheny General Hospital) ;
Rachakonda, Vikrant (University of California) ;
Duarte-Rojo, Andres (University of Pittsburgh Medical Center) ;
Bataller, Ramon (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
The prevalence and impact of alcohol withdrawal syndrome (AWS) in patients with alcohol-associated hepatitis (AH) are unknown. In this study, we aimed to investigate the prevalence, predictors, management, and clinical impact of AWS in patients hospitalized with AH. [...]
2023 - 10.1016/j.eclinm.2023.102046
EClinicalMedicine, Vol. 61 (june 2023)
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12 p, 1022.2 KB |
Bariatric Surgery Is Associated with Alcohol-Related Liver Disease and Psychiatric Disorders Associated with AUD
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Alvarado-Tapias, Edilmar (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Marti-Aguado, David (Institut d'Investigació Biomèdica INCLIVA) ;
Kennedy, Kevin (Kansas City) ;
Fernández-Carrillo, Carlos (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Ventura-Cots, Meritxell (Hospital Universitari Vall d'Hebron) ;
Morales-Arraez, Dalia (Hospital Universitario de Canarias (La Laguna)) ;
Atkinson, Stephen R. (Imperial College London) ;
Clemente-Sanchez, Ana (Hospital General Universitario Gregorio Marañón) ;
Argemi, Josepmaria (Clínica Universidad de Navarra) ;
Bataller, Ramon (Universitat de Barcelona) ;
Universitat Autònoma de Barcelona
Bariatric surgery can increase the risk of addictive disorders and nutritional deficiencies. The aim of this study was to evaluate the association between bariatric surgery and alcohol use disorder (AUD), alcohol-related liver disease (ALD), and psychiatric disorders associated with AUD. [...]
2023 - 10.1007/s11695-023-06490-w
Obesity Surgery, Vol. 33 (march 2023) , p. 1494-1505
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4 p, 880.1 KB |
A multistrain probiotic increases the serum glutamine/glutamate ratio in patients with cirrhosis : a metabolomic analysis
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Laghi, Luca (University of Bologna) ;
Roman, Eva (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Lan, Qiuyu (University of Bologna) ;
Nieto Sáchica, Juan Camilo (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Canalda-Baltrons, Aleix (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poca Sans, Maria (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sánchez-Rodríguez, Maria B. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Clària, J (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Alvarado-Tapias, Edilmar (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Cuyàs, Berta (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sánchez, Elisabet (Instituto de Salud Carlos III) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Guarner, Carlos (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Escorsell, Àngels (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Manichanh, Chaysavanh (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Soriano, German (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona
To explore the potential mechanisms underlying the effects of a probiotic in cirrhotic patients, we analyzed the blood metabolome using proton nuclear magnetic resonance (1 H-NMR) spectroscopy in 32 patients with cirrhosis and cognitive dysfunction or falls. [...]
2023 - 10.1097/HC9.0000000000000072
Hepatology Communications, Vol. 7 (april 2023)
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7.
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12 p, 780.3 KB |
PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis
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Trebicka, Jonel (Department of Internal Medicine I. Goethe University Frankfurt) ;
Fernández, Javier (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Papp, Maria (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Caraceni, Paolo (University of Bologna) ;
Laleman, Wim (University of Leuven) ;
Gambino, Carmine (University of Padova) ;
Giovo, Ilaria (A.O.U. Città della Salute e della Scienza Torino) ;
Uschner, Frank Erhard (Department of Internal Medicine I. Goethe University Frankfurt) ;
Jansen, Christian (Department of Internal Medicine I. University Hospital Bonn) ;
Jimenez, Cesar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mookerjee, Rajeshwar Prosad (UCL Medical School. Royal Free Hospital) ;
Gustot, Thierry (C.U.B. Erasme) ;
Albillos, Agustín (Hospital Universitario Ramón y Cajal (Madrid)) ;
Bañares, Rafael (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Jarcuska, Peter (Pavol Jozef Safarik University in Kosice) ;
Steib, Christian (Department of Medicine II. Liver Centre Munich. University Hospital. LMU) ;
Reiberger, Thomas (Medical University of Vienna) ;
Acevedo, Juan (University Hospitals Plymouth NHS Trust (Regne Unit)) ;
Gatti, Pietro (Internal Medicine PO Ostuni) ;
Shawcross, Debbie (King's College Hospital NHS Foundation Trust) ;
Zeuzem, Stefan (Department of Internal Medicine I. Goethe University Frankfurt) ;
Zipprich, Alexander (University Hospital Halle-Wittenberg) ;
Piano, Salvatore (University of Padova) ;
Berg, Thomas (Division of Hepatology. Department of Medicine II. Leipzig University. Medical Center) ;
Bruns, Tony (Aachen University Hospital) ;
Danielsen, Karen Vagner (University of Copenhagen) ;
Coenraad, Minneke (Leiden University Medical Center) ;
Merli, Manuela (Universitá Sapienza Roma) ;
Stauber, Rudolf (Medical University of Graz) ;
Zoller, Heinz (Medical University of Innsbruck) ;
Presa Ramos, José (CHTMAD Vila Real-Blueclinical) ;
Solé, Cristina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Soriano, German (Institut d'Investigació Biomèdica Sant Pau) ;
De Gottardi, Andrea (University Clinic of Visceral Surgery and Medicine-Inselspital. Bern and Ente Ospedaliero Cantonale. Universita della Svizzera Italiana) ;
Gronbaek, Henning (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Saliba, Faouzi (AP-HP Hôpital Paul Brousse. Centre Hépato-Biliaire. Universite Paris Saclay. INSERM Unit 1193) ;
Trautwein, Christian (Aachen University Hospital) ;
Kani, Haluk Tarik (Marmara University) ;
Francque, Sven (University Hospital Antwerp) ;
Ryder, Stephen David (NIHR Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham) ;
Nahon, Pierre (Inserm. UMR-1162. "Génomique fonctionnelle des tumeurs solides") ;
Romero-Gomez, Manuel (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Van Vlierberghe, Hans (Universitair Ziekenhuis Gent) ;
Francoz, Claire (Inserm. Université de Paris. Centre de Recherche sur L'Inflammation) ;
Manns, Michael (Hannover Medical School) ;
Garcia-Lopez, Elisabet (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Tufoni, Manuel (University of Bologna) ;
Amoros, Alex (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Pavesi, Marco (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Sanchez, Cristina (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Praktiknjo, Michael (Department of Internal Medicine I. University Hospital Bonn) ;
Curto, Anna (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Pitarch, Carla (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Putignano, Antonella (C.U.B. Erasme) ;
Moreno, Esau (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Bernal, William (King's College Hospital NHS Foundation Trust) ;
Aguilar, Ferran (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Clària, J (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ponzo, Paola (A.O.U. Città della Salute e della Scienza Torino) ;
Vitalis, Zsuzsanna (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Zaccherini, Giacomo (University of Bologna) ;
Balogh, Boglarka (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Gerbes, Alexander L (Department of Medicine II. Liver Centre Munich. University Hospital. LMU) ;
Vargas, Victor (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alessandria, Carlo (A.O.U. Città della Salute e della Scienza Torino) ;
Bernardi, Mauro (University of Bologna) ;
Ginès, Pere (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Moreau, Richard (Inserm. Université de Paris. Centre de Recherche sur L'Inflammation) ;
Angeli, Paolo (University of Padova) ;
Jalan, Rajiv (UCL Medical School. Royal Free Hospital) ;
Arroyo, Vicente (European Foundation for Study of Chronic Liver Failure. EF-Clif) ;
Maschmeier, Miriam (Munster University Hospital) ;
Semela, David (University of Basel-St Gall Cantonal Hospital) ;
Elkrief, Laure (Hôpitaux Universitaires de Genève) ;
Elsharkawy, Ahmed (University of Birmingham) ;
Tornai, Tamas (University of Birmingham) ;
Tornai, Istvan (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Altorjay, Istvan (University of Debrecen. Faculty of Medicine. Institute of Medicine. Department of Gastroenterology) ;
Antognoli, Agnese (University of Bologna) ;
Baldassarre, Maurizio (University of Bologna) ;
Gagliardi, Martina (University of Bologna) ;
Bertoli, Eleonora (University of Padova) ;
Mareso, Sara (University of Padova) ;
Brocca, Alessandra (University of Padova) ;
Campion, Daniela (A.O.U. Città della Salute e della Scienza Torino) ;
Saracco, Giorgio Maria (A.O.U. Città della Salute e della Scienza Torino) ;
Rizzo, Martina (A.O.U. Città della Salute e della Scienza Torino) ;
Lehmann, Jennifer (University Hospital Bonn (Bonn, Alemanya)) ;
Pohlmann, Alessandra (University Hospital Bonn (Bonn, Alemanya)) ;
Brol, Maximilian Joseph (University Hospital Bonn (Bonn, Alemanya)) ;
Chang, Johannes (University Hospital Bonn (Bonn, Alemanya)) ;
Schierwagen, Robert (Department of Internal Medicine I. Goethe University Frankfurt) ;
Solà, Elsa (Hospital Clínic i Provincial de Barcelona) ;
Amari, Nesrine (C.U.B. Erasme) ;
Rodriguez, Miguel (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Nevens, Frederik (Department of Gastroenterology and Hepatology. Section of Liver and Biliopancreatic disorders. University of Leuven) ;
Clemente, Ana (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Janicko, Martin (Pavol Jozef Safarik University in Kosice) ;
Markwardt, Daniel (Department of Medicine II. Liver Centre Munich. University Hospital. LMU) ;
Mandorfer, Mattias (Medical University of Vienna) ;
Welsch, Christoph (Department of Internal Medicine I. Goethe University Frankfurt) ;
Welzel, Tanja M. (Department of Internal Medicine I. Goethe University Frankfurt) ;
Ciraci, Emanuela (Internal Medicine PO Ostuni) ;
Patel, Vish (King's College Hospital NHS Foundation Trust) ;
Ripoll, Cristina (University Hospital Halle-Wittenberg) ;
Herber, Aadam (Division of Hepatology. Department of Medicine II. Leipzig University. Medical Center) ;
Horn, Paul (Jena University Hospital (Alemanya)) ;
Bendtsen, Flemming (Gastrounit. Medical Section. Hvidovre Hospital and Department of Clinical Medicine. University of Copenhagen) ;
Gluud, Lise Lotte (Gastrounit. Medical Section. Hvidovre Hospital and Department of Clinical Medicine. University of Copenhagen) ;
Schaapman, Jelte (Leiden University Medical Center) ;
Riggio, Oliviero (Universitá Sapienza Roma) ;
Rainer, Florian (Medical University of Graz) ;
Moritz, Jörg Tobiasch (Medical University of Innsbruck) ;
Mesquita, M. (CHTMAD Vila Real-Blueclinical) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Akpata, Osagie (UCL Medical School. Royal Free Hospital) ;
Aamann, Luise (Aarhus University Hospital (Aarhus, Dinamarca)) ;
Samuel, Didier (AP-HP Hôpital Paul Brousse. Centre Hépato-Biliaire. Universite Paris Saclay. INSERM Unit 1193) ;
Tresson, Sylvie (AP-HP Hôpital Paul Brousse. Centre Hépato-Biliaire. Universite Paris Saclay. INSERM Unit 1193) ;
Strnad, Pavel (Aachen University Hospital) ;
Amathieu, Roland (Inserm. UMR-1162. "Génomique fonctionnelle des tumeurs solides") ;
Simón-Talero, Macarena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Smits, Francois (C.U.B. Erasme) ;
van den Ende, Natalie (Department of Gastroenterology and Hepatology. Section of Liver and Biliopancreatic disorders. University of Leuven) ;
Martinez, Javier (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Garcia, Rita (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Rupprechter, Harald (Medical University of Vienna) ;
Engelmann, Cornelius (Division of Hepatology. Department of Medicine II. Leipzig University. Medical Center) ;
Özdogan, Osman Cavit (Marmara University) ;
Universitat Autònoma de Barcelona
Background & Aims: Acute decompensation (AD) of cirrhosis may present without acute-on-chronic liver failure (ACLF) (AD-No ACLF), or with ACLF (AD-ACLF), defined by organ failure(s). Herein, we aimed to analyze and characterize the precipitants leading to both of these AD phenotypes. [...]
2021 - 10.1016/j.jhep.2020.11.019
Journal of Hepatology, Vol. 74 Núm. 5 (may 2021) , p. 1097-1108
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6 p, 292.0 KB |
Serum miR-181b-5p predicts ascites onset in patients with compensated cirrhosis
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Garcia Garcia de Paredes, Ana (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Villanueva, Càndid (Institut d'Investigació Biomèdica Sant Pau) ;
Blanco, Carolina (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Genescà Ferrer, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Manicardi, Nicolo (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Garcia-Pagan, Juan Carlos (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Calleja, Jose Luis (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Aracil, Carlos (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Morillas Cunill, Rosa Ma (Universitat Autònoma de Barcelona) ;
Poca Sans, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Peñas, Beatriz (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Augustin Recio, Salvador (Hospital Universitari Vall d'Hebron) ;
Abraldes, Juan G. (University of Alberta) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Royo, Félix (Exosomes Laboratory. Center for Cooperative Research in Biosciencies (CIC bioGUNE). Basque Research and Technology Alliance (BRTA)) ;
García-Bermejo, Mª Laura (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ;
Falcon-Perez, Juan Manuel (Exosomes Laboratory. Center for Cooperative Research in Biosciencies (CIC bioGUNE). Basque Research and Technology Alliance (BRTA)) ;
Bañares, Rafael (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Bosch, Jaime (Department of Biomedical Research and University Clinic for Visceral Medicine and Surgery. Inselspital) ;
Gracia-Sancho, Jordi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Albillos, Agustín (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Universitat Autònoma de Barcelona
Background & Aims: Treatment with non-selective beta-blockers (NSBBs) reduces the risk of ascites, which is the most common decompensating event in cirrhosis. This study aimed to assess the ability of a serum microRNA (miRNA) signature to predict ascites formation and the hemodynamic response to NSBBs in compensated cirrhosis. [...]
2021 - 10.1016/j.jhepr.2021.100368
JHEP Reports, Vol. 3 Núm. 6 (december 2021) , p. 100368
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12 p, 1.1 MB |
Effects of albumin on survival after a hepatic encephalopathy episode : Randomized double-blind trial and meta-analysis
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Ventura-Cots, Meritxell (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Simón-Talero, Macarena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Poca Sans, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Ariza, Xavier (Hospital Clínic i Provincial de Barcelona) ;
Masnou, Helena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sánchez-Delgado, Jordi (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Llop, Elba (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Cañete Hidalgo, Nuria (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Martín-Llahí, Marta (Hospital de Sant Joan Despí Moisès Broggi) ;
Amador, Alberto (Institut d'Investigació Biomèdica de Bellvitge) ;
Martínez, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Clemente-Sanchez, Ana (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Puente, Angela (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Torrens, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Napoleone, Laura (Hospital Clínic i Provincial de Barcelona) ;
Miquel Planas, Mireia (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ardèvol Ribalta, Alba (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Casas Rodrigo, Meritxell (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Calleja, Jose Luis (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Solé, Cristina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Soriano, German (Institut d'Investigació Biomèdica Sant Pau) ;
Genescà Ferrer, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
No therapies have been proven to increase survival after a hepatic encephalopathy (HE) episode. We hypothesize that two doses of albumin could improve 90-day survival rates after a HE episode. Methods: (1) A randomized double-blind, placebo-controlled trial (BETA) was conducted in 12 hospitals. [...]
2021 - 10.3390/jcm10214885
Journal of clinical medicine, Vol. 10 Núm. 21 (11 2021) , p. 4885
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11 p, 1.2 MB |
Phase angle by electrical bioimpedance is a predictive factor of hospitalisation, falls and mortality in patients with cirrhosis
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Román, E. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Poca Pastor, María Antonia (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Amorós-Figueras, Gerard (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Rosell-Ferrer, J. (Universitat Politècnica de Catalunya) ;
Gely, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Nieto Sáchica, Juan Camilo (Institut d'Investigació Biomèdica Sant Pau) ;
Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Urgell, Eulàlia (Institut d'Investigació Biomèdica Sant Pau) ;
Ferrero-Gregori, A. (Foundation for the Promotion of Health and Biomedical Research of Valencia Region (FISABIO)) ;
Alvarado-Tapias, Edilmar (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Cuyàs, Berta (Institut d'Investigació Biomèdica Sant Pau) ;
Hernández, Elvira (Universitat Autònoma de Barcelona) ;
Santesmases Masana, Rosalia (Universitat Autònoma de Barcelona) ;
Guarner-Argente, Carlos (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Escorsell, Àngels (Institut d'Investigació Biomèdica Sant Pau) ;
Soriano, G.. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas)
The phase angle is a versatile measurement to assess body composition, frailty and prognosis in patients with chronic diseases. In cirrhosis, patients often present alterations in body composition that are related to adverse outcomes. [...]
2021 - 10.1038/s41598-021-99199-8
Scientific reports, Vol. 11 Núm. 1 (december 2021) , p. 20415
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