Resultados globales: 6 registros encontrados en 0.02 segundos.
Artículos, Encontrados 6 registros
Artículos Encontrados 6 registros  
1.
19 p, 2.4 MB Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations / Temprano-Sagrera, Gerard (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Sitlani, Collen M. (University of Washington) ; Bone, William P. (University of Pennsylvania) ; Martín Bórnez, Miguel (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Voight, Benjamin F. (University of Pennsylvania Perelman School of Medicine) ; Morrison, Alanna C. ; Damrauer, Scott M. ; de Vries, Paul S. ; Smith, Nicholas L. ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Dehghan, Abbas ; Heath, Adam S. ; Reiner, Alex P. ; Johnson, Andrew ; Richmond, Anne ; Peters, Annette ; van Hylckama Vlieg, Astrid ; McKnight, Barbara ; Psaty, Bruce M. ; Hayward, Caroline ; Ward-Caviness, Cavin ; O'Donnell, Cristopher ; Chasman, Daniel ; Strachan, David P. ; Tregouet, David A. ; Mook-Kanamori, Dennis ; Gill, Dipender ; Thibord, Florian ; Asselbergs, Folkert W. ; Leebeek, Frank W. G. ; Rosendaal, Frits R. ; Davies, Gail ; Homuth, Georg ; Temprano, Gerard ; Campbell, Harry ; Taylor, Herman A. ; Bressler, Jan ; Huffman, Jennifer E. ; Rotter, Jerome I. ; Yao, Jie ; Wilson, James F. ; Bis, Joshua C. ; Hahn, Julie M. ; Desch, Karl C. ; Wiggins, Kerri L. ; Raffield, Laura M. ; Bielak, Lawrence F. ; Yanek, Lisa R. ; Kleber, Marcus E. ; Mueller, Martina ; Kavousi, Maryam ; Mangino, Massimo ; Liu, Melissa ; Brown, Michael R. ; Conomos, Matthew P. ; Jhun, Min-A. ; Chen, Ming-Huei ; de Maat, Moniek P. M. ; Pankratz, Nathan ; Smith, Nicholas L. ; Peyser, Patricia A. ; Elliot, Paul ; Wei, Peng ; Wild, Philipp S. ; Morange, Pierre E. ; van der Harst, Pim ; Yang, Qiong ; Le, Ngoc-Quynh ; Marioni, Riccardo ; Li, Ruifang ; Damrauer, Scott M. ; Cox, Simon R. ; Trompet, Stella ; Felix, Stephan B. ; Völker, Uwe ; Tang, Weihong ; Koenig, Wolfgang ; Jukema, J. Wouter ; Guo, Xiuqing ; Lindstrom, Sara ; Wang, Lu ; Smith, Erin N. ; Gordon, William ; van Hylckama Vlieg, Astrid ; de Andrade, Mariza ; Brody, Jennifer A. ; Pattee, Jack W. ; Haessler, Jeffrey ; Brumpton, Ben M. ; Suchon, Pierre ; Chen, Ming-Huei ; Turman, Constance ; Germain, Marine ; Wiggins, Kerri L. ; MacDonald, James ; Braekkan, Sigrid K. ; Armasu, Sebastian M. ; Pankratz, Nathan ; Jackson, Rabecca D. ; Nielsen, Jonas B. ; Giulianini, Franco ; Puurunen, Marja K. ; Ibrahim, Manal ; Heckbert, Susan R. ; Bammler, Theo K. ; Frazer, Kelly A. ; McCauley, Bryan M. ; Taylor, Kent ; Pankow, James S. ; Reiner, Alexander P. ; Gabrielsen, Maiken E. ; Deleuze, Jean-François ; O'Donnell, Chris J. ; Kim, Jihye ; McKnight, Barbara ; Kraft, Peter ; Hansen, John-Bjarne ; Rosendaal, Frits R. ; Heit, John A. ; Psaty, Bruce M. ; Tang, Weihong ; Kooperberg, Charles ; Hveem, Kristian ; Ridker, Paul M. ; Morange, Pierre-Emmanuel ; Johnson, Andrew D. ; Kabrhel, Christopher ; Trégouët, David-Alexandre ; Smith, Nicholas L. ; Malik, Rainer ; Chauhan, Ganesh ; Traylor, Matthew ; Sargurupremraj, Muralidharan ; Okada, Yukinori ; Mishra, Aniket ; Rutten-Jacobs, Loes ; Giese, Anne-Katrin ; van der Laan, Sander W. ; Gretarsdottir, Solveig ; Anderson, Christopher D. ; Chong, Michael ; Adams, Hieab HH. ; Ago, Tetsuro ; Almgren, Peter ; Amouyel, Philippe ; Ay, Hakan ; Bartz, Traci M. ; Benavente, Oscar R. ; Bevan, Steve ; Boncoraglio, Giorgio B. ; Brown, Robert D. ; Butterworth, Aadam S. ; Carrera, Caty ; Carty, Cara L. ; Chen, Wei-Min ; Cole, John W. ; Correa, Adolfo ; Cotlarciuc, Ioanna ; Cruchaga, Carlos ; Danesh, John ; de Bakker, Paul I. W. ; DeStefano, Anita L. ; den Hoed, Marcel ; Duan, Qing ; Engelter, Stefan T. ; Falcone, Guido J. ; Gottesman, Rebecca F. ; Grewal, Raji P. ; Gudnason, Vilmundur ; Gustafsson, Stefan ; Haessler, Jeffrey ; Harris, Tamara B. ; Hassan, Ahamad ; Havulinna, Aki S. ; Heckbert, Susan R. ; Holliday, Elizabeth G. ; Howard, George ; Hsu, Fang-Chi ; Hyacinth, Hyacinth I. ; Arfan Ikram, M. ; Ingelsson, Erik ; Irvin, Marguerite R. ; Jian, Xueqiu ; Jiménez-Conde, Jordi ; Johnson, Julie A. ; Jukema, J. Wouter ; Kanai, Masahiro ; Keene, Keith L. ; Kissela, Brett M. ; Kleindorfer, Dawn O. ; Kooperberg, Charles ; Kubo, Michiaki ; Lange, Leslie A. ; Langefeld, Carl D. ; Langenberg, Claudia ; Launer, Lenore J. ; Lee, Jin-Moo ; Lemmens, Robin ; Leys, Didier ; Lewis, Cathryn M. ; Lin, Wei-Yu ; Lindgren, Arne G. ; Lorentzen, Erik ; Magnusson, Patrik K. ; Maguire, Jane ; Manichaikul, Ani ; McArdle, Patrick F. ; Meschia, James F. ; Mitchell, Braxton D. ; Mosley, Thomas H. ; Nalls, Michael A. ; Ninomiya, Toshiharu ; O'Donnell, Martin J. ; Psaty, Bruce M. ; Pulit, Sara L. ; Rannikmäe, Kristiina ; Reiner, Alexander P. ; Rexrode, Kathryn M. ; Rice, Kenneth ; Rich, Stephen S. ; Ridker, Paul M. ; Rost, Natalia S. ; Rothwell, Peter M. ; Rotter, Jerome I. ; Rundek, Tatjana ; Sacco, Ralph L. ; Sakaue, Saori ; Sale, Michele M. ; Salomaa, Veikko ; Sapkota, Bishwa R. ; Schmidt, Reinhold ; Schmidt, Carsten O. ; Schminke, Ulf ; Sharma, Pankaj ; Slowik, Agnieszka ; Sudlow, Cathie L. M. ; Tanislav, Christian ; Tatlisumak, Turgut ; Taylor, Kent D. ; Thijs, Vincent N. S. ; Thorleifsson, Gudmar ; Thorsteinsdottir, Unnur ; Tiedt, Steffen ; Trompet, Stella ; Tzourio, Christophe ; van Duijn, Cornelia M. ; Walters, Matthew ; Wareham, Nicholas J. ; Wassertheil-Smoller, Sylvia ; Wilson, James G. ; Wiggins, Kerri L. ; Yang, Qiong ; Yusuf, Salim ; Amin, Najaf ; Aparicio, Hugo S. ; Arnett, Donna K. ; Attia, John ; Beiser, Alexa S. ; Berr, Claudine ; Buring, Julie E. ; Bustamante, Mariana ; Caso, Valeria ; Cheng, Yu-Ching ; Hoan Choi, Seung ; Chowhan, Ayesha ; Cullell, Natalia ; Dartigues, Jean-François ; Delavaran, Hossein ; Delgado, Pilar ; Dörr, Marcus ; Engström, Gunnar ; Ford, Ian ; Gurpreet, Wander S. ; Hamsten, Anders ; Heitsch, Laura ; Hozawa, Aatsushi ; Ibanez, Laura ; Ilinca, Andrea ; Ingelsson, Martin ; Iwasaki, Motoki ; Jackson, Rebecca D. ; Jood, Katarina ; Jousilahti, Pekka ; Kaffashian, Sara ; Kalra, Lalit ; Kamouchi, Masahiro ; Kitazono, Takanari ; Kjartansson, Olafur ; Kloss, Manja ; Koudstaal, Peter J. ; Krupinski, Jerzy ; Labovitz, Daniel L. ; Laurie, Cathy C. ; Levi, Christhoper R. ; Li, Linxin ; Lind, Lars ; Lindgren, Cecilia M. ; Lioutas, Vasileios ; Mei Liu, Yong ; Lopez, Oscar L. ; Makoto, Hirata ; Martinez-Majander, Nicolas ; Matsuda, Koichi ; Minegishi, Naoko ; Montaner, Joan ; Morris, Andrew P. ; Muiño, Elena ; Müller-Nurasyid, Martina ; Norrving, Bo ; Ogishima, Soichi ; Parati, Eugenio A. ; Reddy Peddareddygari, Leema ; Pedersen, Nancy L. ; Pera, Joanna ; Perola, Markus ; Pezzini, Alessandro ; Pileggi, Silvana ; Rabionet, Raquel ; Riba-Llena, Iolanda ; Ribasés, Marta ; Romero, Jose R. ; Roquer, Jaume ; Rudd, Anthony G. ; Sarin, Antti-Pekka ; Sarju, Ralhan ; Sarnowski, Chloe ; Sasaki, Makoto ; Satizabal, Claudia L. ; Satoh, Mamoru ; Sattar, Naveed ; Sawada, Norie ; Sibolt, Gerli ; Sigurdsson, Ásgeir ; Smith, Albert ; Sobue, Kenji ; Soriano-Tárraga, Carolina ; Stanne, Tara ; Colin Stine, O. ; Stott, David J. ; Strauch, Konstantin ; Takai, Takako ; Tanaka, Hideo ; Tanno, Kozo ; Teumer, Alexander ; Tomppo, Liisa ; Torres-Aguila, Nuria P. ; Touze, Emmanuel ; Tsugane, Shoichiro ; Uitterlinden, Aandre G. ; Valdimarsson, Einar M. ; van der Lee, Sven J. ; Völzke, Henry ; Wakai, Kenji ; Weir, David ; Williams, Stephen R. ; Wolfe, Charles D.A. ; Wong, Quenna ; Xu, Huichun ; Yamaji, Taiki ; Sanghera, Dharambir K. ; Melander, Olle ; Jern, Christina ; Strbian, Daniel ; Fernandez-Cadenas, Israel ; Longstreth, W.T. ; Rolfs, Arndt ; Hata, Jun ; Woo, Daniel ; Rosand, Jonathan ; Pare, Guillaume ; Hopewell, Jemma C. ; Saleheen, Danish ; Stefansson, Kari ; Worrall, BradfordB. ; Kittner, Steven J. ; Seshadri, Sudha ; Fornage, Myriam ; Markus, Hugh S. ; Howson, Joana M. M. ; Kamatani, Yoichiro ; Debette, Stephanie ; Dichgans, Martin ; Universitat Autònoma de Barcelona
Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively analyze the shared genetic effects within different hemostatic traits, and between these and their associated disease outcomes. [...]
2022 - 10.1111/jth.15698
Journal of Thrombosis and Haemostasis, Vol. 20 Núm. 6 (01 2022) , p. 1331-1349  
2.
9 p, 2.7 MB Genetic association study of childhood aggression across raters, instruments, and age / Ip, Hill F. (Vrije Universiteit Amsterdam) ; van der Laan, Camiel M. (Netherlands Institute for the Study of Crime and Law Enforcement) ; Krapohl, Eva M. L. (King's College London) ; Brikell, Isabell (Karolinska Institutet (Estocolm, Suècia)) ; Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Nolte, Ilja M. (University of Groningen) ; Pourcain, Beate St (Radboud University) ; Bolhuis, Koen (Erasmus University Medical Center) ; Palviainen, Teemu (University of Helsinki) ; Zafarmand, Hadi (University of Amsterdam) ; Colodro-Conde, Lucía (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Gordon, Scott D (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Zayats, Tetyana (Stanley Center for Psychiatric Research) ; Aliev, Fazil (Karabuk University) ; Jiang, Chang (University of Florida) ; Wang, Carol A. (The University of Newcastle) ; Saunders, Gretchen (University of Minnesota) ; Karhunen, Ville (Imperial College London) ; Hammerschlag, Anke R. (Amsterdam Public Health Research Institute) ; Adkins, Daniel E. (University of Utah) ; Border, Richard (University of Colorado Boulder) ; Peterson, Roseann E. (Virginia Commonwealth University) ; Prinz, Joseph A. (Duke University) ; Thiering, Elisabeth (Ludwig-Maximilians-University of Munich) ; Seppälä, Ilkka (Tampere University) ; Vilor-Tejedor, Natàlia (Fundació Pasqual Maragall (FPM)) ; Ahluwalia, Tarunveer Singh (Steno Diabetes Center Copenhagen) ; Day, Felix R. (University of Cambridge School of Clinical Medicine) ; Hottenga, Jouke Jan (Vrije Universiteit Amsterdam) ; Allegrini, Andrea G. (King's College London) ; Rimfeld, Kaili (King's College London) ; Chen, Qi (Karolinska Institutet (Estocolm, Suècia)) ; Lu, Yi (Karolinska Institutet (Estocolm, Suècia)) ; Martin, Joanna (Cardiff University) ; Soler Artigas, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rovira, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Bosch, Rosa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Español-Martín, Gemma (Hospital Universitari Vall d'Hebron) ; Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Neumann, Alexander (Jewish General Hospital) ; Ensink, Judith (De Bascule, Academic Centre for Child and Adolescent Psychiatry) ; Grasby, Katrina (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Morosoli, José J. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Tong, Xiaoran (University of Florida) ; Marrington, Shelby (The University of Queensland) ; Middeldorp, Christel (Children's Health Queensland Hospital) ; Scott, James G. (Queensland Centre for Mental Health Research) ; Vinkhuyzen, Anna (University of Queensland) ; Shabalin, Andrey A. (University of Utah) ; Corley, Robin (University of Colorado Boulder) ; Evans, Luke M. (University of Colorado Boulder) ; Sugden, Karen (Duke University) ; Alemany, Sílvia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Sass, Lærke (University of Copenhagen) ; Vinding, Rebecca (University of Copenhagen) ; Ruth, Kate (University of Exeter Medical School) ; Tyrrell, Jess (University of Exeter Medical School) ; Davies, Gareth E. (Avera Institute for Human Genetics) ; Ehli, Erik A. (Avera Institute for Human Genetics) ; Hagenbeek, Fiona A. (Vrije Universiteit Amsterdam) ; De Zeeuw, Eveline (Vrije Universiteit Amsterdam) ; Van Beijsterveldt, Toos C.E.M. (Vrije Universiteit Amsterdam) ; Larsson, Henrik (Orebro University) ; Snieder, Harold (University of Groningen) ; Verhulst, Frank C. (Copenhagen University Hospital) ; Amin, Najaf (Erasmus University Medical Center) ; Whipp, Alyce M. (University of Helsinki) ; Korhonen, Tellervo (University of Helsinki) ; Vuoksimaa, Eero (University of Helsinki) ; Rose, Richard J. (Indiana University) ; Uitterlinden, André G. (Netherlands Genomics Initiative (NGI)) ; Heath, Andrew C. (Washington University) ; Madden, Pamela (Washington University) ; Haavik, Jan (Haukeland University Hospital (Bergen, Noruega)) ; Harris, Jennifer R. (The Norwegian Institute of Public Health) ; Helgeland, Øyvind (The Norwegian Institute of Public Health) ; Johansson, Stefan E (University of Bergen) ; Knudsen, Gun Peggy S. (The Norwegian Institute of Public Health) ; Njolstad, Pal Rasmus (University of Bergen) ; Lu, Qing (University of Florida) ; Rodriguez, Alina (University of Lincoln) ; Henders, Anjali K. (University of Queensland) ; Mamun, Abdullah (University of Queensland) ; Najman, Jackob M. (The University of Queensland) ; Brown, Sandy (University of California) ; Hopfer, Christian (University of Colorado School of Medicine) ; Krauter, Kenneth (University of Colorado Boulder) ; Reynolds, Chandra (University of California Riverside) ; Smolen, Andrew (University of Colorado Boulder) ; Stallings, Michael (University of Colorado Boulder) ; Wadsworth, Sally (University of Colorado Boulder) ; Wall, Tamara L. (University of California) ; Silberg, Judy L. (Virginia Commonwealth University) ; Miller, Allison (University of Otago Christchurch) ; Keltikangas-Järvinen, Liisa (University of Helsinki) ; Hakulinen, Christian (University of Helsinki) ; Pulkki-Råback, Laura (University of Helsinki) ; Havdahl, Alexandra (Norwegian Institute of Public Health) ; Magnus, Per (Norwegian Institute of Public Health) ; Raitakari, Olli T. (Turku University Hospital) ; Perry, John R. B. (University of Cambridge School of Clinical Medicine) ; Llop, Sabrina (Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; Lopez-Espinosa, Maria-Jose (Universitat de València) ; Bønnelykke, Klaus (University of Copenhagen) ; Bisgaard, Hans (University of Copenhagen) ; Sunyer Deu, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lehtimäki, Terho (Tampere University) ; Arseneault, Louise (Duke University School of Medicine) ; Standl, Marie (Helmholtz Zentrum München) ; Heinrich, Joachim (University of Melbourne) ; Boden, Joseph (University of Otago Christchurch) ; Pearson, John (University of Otago Christchurch) ; Horwood, L. John (University of Otago Christchurch) ; Kennedy, Martin (University of Otago Christchurch) ; Poulton, Richie (University of Otago) ; Eaves, Lindon J. (Virginia Institute for Psychiatric and Behavioral Genetics) ; Maes, Hermine H. (Virginia Commonwealth University) ; Hewitt, John (University of Colorado Boulder) ; Copeland, William E. (University of Vermont) ; Costello, Elizabeth J. (Duke University) ; Williams, Gail M. (The University of Queensland) ; Wray, Naomi R (University of Queensland) ; Järvelin, Marjo-Riitta (University of Oulu) ; McGue, Matt (University of Minnesota) ; Iacono, William (University of Minnesota) ; Caspi, Avshalom (King's College London) ; Moffitt, Terrie E. (King's College London) ; Whitehouse, Andrew (The University of Western Australia) ; Pennell, Craig E. (The University of Newcastle) ; Klump, Kelly L. (Michigan State University) ; Burt, S. Alexandra (Michigan State University) ; Dick, Danielle M. (Virginia Commonwealth University) ; Reichborn-Kjennerud, Ted (University of Oslo) ; Martin, Nicholas G (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Medland, Sarah Elizabeth (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Vrijkotte, Tanja (University of Amsterdam) ; Kaprio, Jaakko (University of Helsinki) ; Tiemeier, Henning (Harvard TH Chan School of Public Health) ; Smith, George Davey (University of Bristol) ; Hartman, Catharina A. (University of Groningen) ; Oldehinkel, Albertine J (University of Groningen) ; Casas Brugué, Miquel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lichtenstein, Paul (Karolinska Institutet (Estocolm, Suècia)) ; Lundström, Sebastian (University of Gothenburg) ; Plomin, Robert (King's College London) ; Bartels, Meike (Amsterdam Public Health Research Institute) ; Nivard, Michel G. (Vrije Universiteit Amsterdam) ; Boomsma, Dorret I (Amsterdam Public Health Research Institute)
Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors were included. [...]
2021 - 10.1038/s41398-021-01480-x
Translational psychiatry, Vol. 11 (july 2021)  
3.
33 p, 4.9 MB New insights into the genetic etiology of Alzheimer's disease and related dementias / Bellenguez, Céline (Université de Lille. INSERM. CHU Lille. Institut Pasteur Lille. U1167-RID-AGE. Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Küçükali, Fahri (University of Antwerp) ; Jansen, Iris E. (Department of Complex Trait Genetics. Center for Neurogenomics and Cognitive Research. Amsterdam Neuroscience. Vrije University) ; Kleineidam, Luca (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Moreno-Grau, Sonia (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Amin, Najaf (Nuffield Department of Population Health. Oxford University) ; Naj, Adam C. (University of Pennsylvania Perelman School of Medicine) ; Campos-Martin, Rafael (Universität zu Köln (Colònia, Alemaya). Department of Psychiatry and Psychotherapy) ; Grenier-Boley, Benjamin (Université de Lille. INSERM. CHU Lille. Institut Pasteur Lille. U1167-RID-AGE. Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Andrade, Victor (Universität zu Köln (Colònia, Alemaya). Department of Psychiatry and Psychotherapy) ; Holmans, Peter (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Boland, Anne (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Damotte, Vincent (Université de Lille. INSERM. CHU Lille. Institut Pasteur Lille. U1167-RID-AGE. Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; van der Lee, Sven J. (Vrije Universiteit Amsterdam) ; Costa, Marcos R. (Brain Institute. Federal University of Rio Grande do Norte) ; Kuulasmaa, Teemu (Institute of Biomedicine. University of Eastern Finland) ; Yang, Qiong (Framingham Heart Study) ; De Rojas, Itziar (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Bis, Joshua C (Cardiovascular Health Research Unit. Department of Medicine. University of Washington) ; Yaqub, Amber (Department of Epidemiology. Erasmus MC) ; Prokic, Ivana (Department of Epidemiology. Erasmus MC) ; Chapuis, Julien (Université de Lille. INSERM. CHU Lille. Institut Pasteur Lille. U1167-RID-AGE. Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Ahmad, Shahzad (LACDR) ; Giedraitis, Vilmantas (Department of Public Health and Carins Sciences/Geriatrics. Uppsala University) ; Aarsland, Dag (Institute of Psychiatry. Psychology & Neuroscience) ; Garcia-Gonzalez, Pablo (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Abdelnour, Carla (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Alarcón-Martín, Emilio (Department of Surgery. Biochemistry and Molecular Biology. School of Medicine. University of Málaga) ; Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Alegret, Montserrat (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Alvarez, Ignacio (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ; Alvarez, Victoria (Hospital Universitario Central de Asturias) ; Armstrong, Nicola (Curtin University) ; Tsolaki, Anthoula (Alzheimer Hellas) ; Antúnez, Carmen (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; Appollonio, Ildebrando (Neurology Unit. San Gerardo Hospital) ; Arcaro, Marina (Fondazione IRCCS Ca'Granda. Ospedale Policlinico) ; Archetti, Silvana (Department of Laboratory Diagnostics. III Laboratory of Analysis. Brescia Hospital) ; Pastor, Alfonso A. (Institut de Recerca Biomedica de Lleida (IRBLLeida)) ; Arosio, Beatrice (Geriatic Unit. Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ; Athanasiu, Lavinia (NORMENT Centre. University of Oslo) ; Bailly, Henri (EA 4468. Université de Paris. APHP. Hôpital Broca) ; Banaj, Nerisa (Laboratory of Neuropsychiatry. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Baquero, Miquel (Hospital Universitari i Politècnic La Fe (València)) ; Barral, Sandra (Gertrude H. Sergievsky Center. Columbia University) ; Beiser, Alexa (Boston University and the NHLBI's Framingham Heart Study) ; Pastor, Ana Belén (CIEN Foundation/Queen Sofia Foundation Alzheimer Center) ; Below, Jennifer E. (Human Genetics Center. Department of Epidemiology. Human Genetics. and Environmental Sciences. School of Public Health. The University of Texas Health Science Center at Houston) ; Benchek, Penelope (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Benussi, Luisa (IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Berr, Claudine (Université Montpellier, INSERM, Institute for Neurosciences of Montpellier) ; Besse, Céline (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Bessi, Valentina (Azienda Ospedaliero-Universitaria Careggi) ; Binetti, Giuliano (MAC - Memory Clinic. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Bizarro, Alessandra (Geriatrics Unit. Fondazione Policlinico A. Gemelli IRCCS) ; Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ; Boada, Mercè (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Boerwinkle, Eric (Baylor College of Medicine) ; Borroni, Barbara (Centre for Neurodegenerative Disorders. Department of Clinical and Experimental Sciences. University of Brescia) ; Boschi, Silvia (Department of Neuroscience "Rita Levi Montalcini". University of Torino) ; Bossù, Paola (Experimental Neuro-psychobiology Laboratory. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Bråthen, Geir (Department of Neuromedicine and Movement Science. Norwegian University of Science and Technology) ; Bressler, Jan (School of Public Health. University of Texas Health Science Center at Houston) ; Bresner, Catherine (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Brodaty, Henry (Dementia Centre for Research Collaboration. School of Psychiatry. University of New South Wales) ; Brookes, Keeley J. (Biosciences. School of Science and Technology. Nottingham Trent University) ; Brusco, Luis Ignacio (Hospital Interzonal General de Agudos Eva Perón. San Martín) ; Buiza-Rueda, Dolores (Department of Neurology. Erasmus MC) ; Bûrger, Katharina (German Center for Neurodegenerative Diseases (DZNE. Munich)) ; Burholt, Vanessa (Wales Centre for Ageing & Dementia Research. Swansea University) ; Bush, William S. (Department of Population & Quantitative Health Sciences. Case Western Reserve University) ; Calero, Miguel (UFIEC. Instituto de Salud Carlos III) ; Cantwell, Laura B (Department of Pathology and Laboratory Medicine. University of Pennsylvania) ; Chene, Geneviève (Pole Santé Publique. CHU de Bordeaux) ; Chung, Jaeyoon (Department of Medicine (Biomedical Genetics). Boston University School of Medicine) ; Cuccaro, MichaelL. (The John P. Hussman Institute for Human Genomics. University of Miami) ; Carracedo, Ángel (Fundación Pública Galega de Medicina Xenómica- CIBERER-IDIS. University of Santiago de Compostela) ; Cecchetti, Roberta (Institute of Gerontology and Geriatrics. Department of Medicine and Surgery. University of Perugia) ; Cervera Carles, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Charbonnier, Camille (Department of Genetics and CNR-MAJ. Normandie University. UNIROUEN. INSERM U1245. CHU Rouen) ; Chen, Hung-Hsin (Division of Genetic Medicine. Vanderbilt University) ; Chillotti, Caterina (Unit of Clinical Pharmacology. University Hospital of Cagliari) ; Ciccone, Simona (Geriatic Unit. Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ; Claassen, Jurgen A.H.R. (Radboudumc Alzheimer Center. Department of Geriatrics. Radboud University Medical Center) ; Clark, Christopher (Institute for Regenerative Medicine. University of Zürich) ; Conti, Elisa (School of Medicine and Surgery. University of Milano-Bicocca) ; Corma-Gómez, Anaïs (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; Costantini, Emanuele (Department of Neuroscience. Catholic University of Sacred Heart. Fondazione Policlinico Universitario A. Gemelli IRCCS) ; Custodero, Carlo (University of Bari. "A. Moro") ; Daian, Delphine (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Dalmasso, Maria Carolina (Universität zu Köln (Colònia, Alemaya). Department of Psychiatry and Psychotherapy) ; Daniele, Antonio (Department of Neuroscience. Catholic University of Sacred Heart. Fondazione Policlinico Universitario A. Gemelli IRCCS) ; Dardiotis, Efthimios (School of Medicine. University of Thessaly) ; Dartigues, Jean-François (Bordeaux Population Health Research Center. University Bordeaux. INSERM) ; de Deyn, Peter Paul (Department of Neurology. University Medical Center Groningen) ; de Paiva Lopes, Katia (Department of Psychiatry. Icahn School of Medicine at Mount Sinai) ; de Witte, Lot D. (Department of Psychiatry. Icahn School of Medicine at Mount Sinai) ; Debette, Stéphanie (Bordeaux Population Health Research Center. University Bordeaux. INSERM) ; Deckert, Jürgen (Department of Psychiatry. Psychosomatics and Psychotherapy. Center of Mental Health. University Hospital) ; del Ser, Teodoro (CIEN Foundation/Queen Sofia Foundation Alzheimer Center) ; Denning, Nicola (UKDRI@ Cardiff. School of Medicine. Cardiff University) ; DeStefano, Anita (Department of Neurology. Boston University School of Medicine) ; Dichgans, Martin (Munich Cluster for Systems Neurology (SyNergy)) ; Diehl-Schmid, Janine (Klinikum rechts der Isar. Department of Psychiatry and Psychotherapy. Technical University of Munich. School of Medicine) ; Diez-Fairen, Mónica (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ; Rossi, Paolo Dionigi (Geriatic Unit. Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ; Djurovic, Srdjan (NORMENT Centre. University of Oslo) ; Duron, Emmanuelle (EA 4468. Université de Paris. APHP. Hôpital Broca) ; Düzel, Emrah (German Center for Neurodegenerative Diseases (DZNE)) ; Dufouil, Carole (Pole Santé Publique. CHU de Bordeaux) ; Eiriksdottir, Gundy (Icelandic Heart Association) ; Engelborghs, Sebastiaan (Department of Neurology. UZ Brussel) ; Escott-Price, Valentina (UKDRI@ Cardiff. School of Medicine. Cardiff University) ; Espinosa, Ana (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Ewers, Michael (German Center for Neurodegenerative Diseases (DZNE. Munich)) ; Faber, Kelley M. (Department of Medical and Molecular Genetics. Indiana University) ; Fabrizio, Tagliavini (Fondazione IRCCS. Istituto Neurologico Carlo Besta) ; Nielsen, Sune Fallgaard (Department of Clinical Biochemistry. Herlev and Gentofte Hospital) ; Fardo, David W. (Sanders-Brown Center on Aging. Department of Biostatistics. University of Kentucky) ; Farotti, Lucia (Centre for Memory Disturbances. Lab of Clinical Neurochemistry. Section of Neurology. University of Perugia) ; Fenoglio, Chiara (University of Milan) ; Fernández-Fuertes, Marta (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; Ferrari, Raffaele (UCL Institute of Neurology (Regne Unit)) ; Ferreira, Catarina B. (Faculty of Medicine. University of Lisbon) ; Ferri, Evelyn (Geriatic Unit. Fondazione Cà Granda. IRCCS Ospedale Maggiore Policlinico) ; Fin, Bertrand (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Fischer, Peter (Department of Psychiatry. Social Medicine Center East- Donauspital) ; Fladby, Tormod (Institute of Clinical Medicine. University of Oslo) ; Fließbach, Klaus (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Fongang, Bernard (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Fornage, Myriam (School of Public Health. University of Texas Health Science Center at Houston) ; Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Foroud, Tatiana M. (Department of Medical and Molecular Genetics. Indiana University) ; Fostinelli, Silvia (Molecular Markers Laboratory. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Fox, Nick C. (Dementia Research Centre. UCL Queen Square Institute of Neurology) ; Franco-Macías, Emilio (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Bullido, María J. (Centro de Biología Molecular Severo Ochoa (UAM-CSIC)) ; Frank-García, Ana (Hospital Universitario La Paz (Madrid)) ; Froelich, Lutz (Department of Geriatric Psychiatry. Central Institute for Mental Health. Mannheim. University of Heidelberg) ; Fulton-Howard, Brian (Department of Neuroscience. Ronald M. Loeb Center for Alzheimer's Disease. Icahn School of Medicine at Mount Sinai) ; Galimberti, Daniela (University of Milan) ; García-Alberca, Jose Maria (Instituto Andaluz de Neurociencia) ; García-González, Pablo (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Garcia-Madrona, Sebastian (Hospital Universitario Ramón y Cajal (Madrid)) ; Garcia-Ribas, Guillermo (Hospital Universitario Ramón y Cajal (Madrid)) ; Ghidoni, Roberta (Molecular Markers Laboratory. IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli) ; Giegling, Ina (Department of Psychiatry and Psychotherapy. Medical University of Vienna) ; Giorgio, Giaccone (Fondazione IRCCS. Istituto Neurologico Carlo Besta) ; Goate, Alison M. (Department of Genetics and Genomic Sciences. Ronald M. Loeb Center for Alzheimer's Disease Icahn School of Medicine at Mount Sinai) ; Goldhardt, Oliver (Klinikum rechts der Isar. Department of Psychiatry and Psychotherapy. Technical University of Munich. School of Medicine) ; Gomez-Fonseca, Duber (Department of Biostatistics. Epidemiology. and Informatics Perelman School of Medicine. University of Pennsylvania) ; González-Pérez, Antonio (CAEBI. Centro Andaluz de Estudios Bioinformáticos) ; Graff, Caroline (Unit for Hereditary Dementias. Karolinska University Hospital-Solna) ; Grande, Giulia (Aging Research Center. Department of Neurobiology. Care Sciences and Society. Karolinska Institutet and Stockholm University) ; Green, Emma (Institute of Public Health. University of Cambridge) ; Grimmer, Timo (Klinikum rechts der Isar. Department of Psychiatry and Psychotherapy. Technical University of Munich. School of Medicine) ; Grünblatt, Edna (Zurich Center for Integrative Human Physiology. University of Zurich) ; Grunin, Michelle (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Gudnason, Vilmundur (Icelandic Heart Association. Faculty of Medicine. University of Iceland) ; Guetta-Baranes, Tamar (Human Genetics. School of Life Sciences. Life Sciences Building. University Park. University of Nottingham) ; Haapasalo, Annakaisa (AI Virtanen Institute for Molecular Sciences. University of Eastern Finland) ; Hadjigeorgiou, Georgios (Department of Neurology. Medical School. University of Cyprus) ; Haines, Jonathan L. (Department of Population & Quantitative Health Sciences. Case Western Reserve University) ; Hamilton-Nelson, Kara L. (The John P. Hussman Institute for Human Genomics. University of Miami) ; Hampel, Harald (GRC 21. Alzheimer Precision Medicine Initiative (APMI). Sorbonne University. AP-HP. Pitié-Salpêtrière Hospital) ; Hanon, Olivier (EA 4468. Université de Paris. APHP. Hôpital Broca) ; Hardy, John (UCL Institute of Neurology (Regne Unit)) ; Hartmann, Annette M. (Department of Psychiatry and Psychotherapy. Medical University of Vienna) ; Hausner, Lucrezia (Department of Geriatric Psychiatry. Central Institute for Mental Health. Mannheim. University of Heidelberg) ; Harwood, Janet (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Heilmann-Heimbach, Stefanie (Institute of Human Genetics. University of Bonn. School of Medicine & University Hospital Bonn) ; Helisalmi, Seppo (Institute of Clinical Medicine. Internal Medicine. University of Eastern Finland) ; Heneka, Michael T. (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Hernández, Isabel (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Herrmann, Martin J. (Department of Psychiatry. Psychosomatics and Psychotherapy. Center of Mental Health. University Hospital) ; Hoffmann, Per (Institute of Human Genetics. University of Bonn. School of Medicine & University Hospital Bonn) ; Holmes, Clive (Clinical and Experimental Science. Faculty of Medicine. University of Southampton) ; Holstege, Henne (Section Genomics of Neurodegenerative Diseases and Aging. Department of Human Genetics Amsterdam UMC. Vrije Universiteit Amsterdam. Amsterdam UMC) ; Huerto Vilas, Raquel (Institut de Recerca Biomedica de Lleida (IRBLLeida)) ; Hulsman, Marc (Section Genomics of Neurodegenerative Diseases and Aging. Department of Human Genetics Amsterdam UMC. Vrije Universiteit Amsterdam. Amsterdam UMC) ; Humphrey, Jack (Nash Family Department of Neuroscience & Friedman Brain Institute. Icahn School of Medicine at Mount Sinai) ; Biessels, Geert Jan (Department of Neurology. UMC Utrecht Brain Center) ; Jian, Xueqiu (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Johansson, Charlotte (Center for Alzheimer Research. Department NVS. Division of Neurogeriatrics. Karolinska Institutet) ; Jun, Gyungah R. (Medicine Biomedical Genetics Boston University School of Medicine) ; Kastumata, Yuriko (Biostatistics. University of Kentucky College of Public Health) ; Kauwe, John (Department of Biology. Brigham Young University) ; Kehoe, Patrick G. (Translational Health Sciences. Bristol Medical School. University of Bristol) ; Kilander, Lena (Department of Biostatistics. Boston University School of Public Health) ; Ståhlbom, Anne Kinhult (Center for Alzheimer Research. Department NVS. Division of Neurogeriatrics. Karolinska Institutet) ; Kivipelto, Miia (Research & Development. UnitStockholms Sjukhem) ; Koivisto, Anne (Department of Neurosciences. University of Helsinki and Department of Geriatrics. Helsinki University Hospital) ; Kornhuber, Johannes (Department of Psychiatry and Psychotherapy. Universitätsklinikum Erlangen. and Friedrich-Alexander Universität Erlangen-Nürnberg) ; Kosmidis, Mary H. (Laboratory of Cognitive Neuroscience. School of Psychology. Aristotle University of Thessaloniki) ; Kukull, Walter A. (Department of Epidemiology. University of Washington) ; Kuksa, Pavel P. (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; Kunkle, Brian W. (Department of Neurology. Medical School. University of Cyprus) ; Kuzma, Amanda B. (Department of Pathology and Laboratory Medicine. University of Pennsylvania) ; Lage, Carmen (Service of Neurology. University Hospital Marqués de Valdecilla. IDIVAL. University of Cantabria) ; Laukka, Erika J. (Stockholm Gerontology Research Center) ; Launer, Lenore (Intramural Research Program/National Institute on Aging/National Institutes of Health) ; Lauria, Alessandra (Geriatrics Unit. Fondazione Policlinico A. Gemelli IRCCS) ; Lee, Chien-Yueh (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; Lehtisalo, Jenni (Public Health Promotion Unit. Finnish Institute for Health and Welfare) ; Lerch, Ondrej (International Clinical Research Center. St. Anne's University Hospital Brno) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Longstreth, William (Departments of Neurology and Epidemiology. University of Washington) ; Lopez, Oscar (Framingham Heart Study) ; Lopez de Munain, Adolfo (Department of Neurology. Hospital Universitario Donostia. OSAKIDETZA-Servicio Vasco de Salud) ; Love, Seth (Translational Health Sciences. Bristol Medical School. University of Bristol) ; Löwemark, Malin (Department of Biostatistics. Boston University School of Public Health) ; Luckcuck, Lauren (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Lunetta, Kathryn L. (Institute of Biomedicine. University of Eastern Finland) ; Ma, Yiyi (Department of Neurology. Columbia University) ; Macías, Juan (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; MacLeod, Catherine A. (School of Health Sciences. Bangor University) ; Maier, Wolfgang (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Mangialasche, Francesca (Division of Clinical Geriatrics. Center for Alzheimer Research. Care Sciences and Society (NVS). Karolinska Institutet) ; Spallazzi, Marco (Unit of Neurology. University of Parma and AOU) ; Marquié, Marta (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Marshall, Rachel (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Martin, Eden R. (The John P. Hussman Institute for Human Genomics. University of Miami) ; Martín Montes, Angel (Hospital Universitario La Paz (Madrid)) ; Martínez Rodríguez, Carmen (Servicio de Neurología. Hospital Universitario Central de Asturias- Oviedo and Instituto de Investigación Biosanitaria del Principado de Asturias) ; Masullo, Carlo (Institute of Neurology. Catholic University of the Sacred Heart) ; Mayeux, Richard (Gertrude H. Sergievsky Center. Columbia University) ; Mead, Simon (MRC Prion Unit at UCL. UCL Institute of Prion Diseases) ; Mecocci, Patrizia (Institute of Gerontology and Geriatrics. Department of Medicine and Surgery. University of Perugia) ; Medina, Miguel (CIEN Foundation/Queen Sofia Foundation Alzheimer Center) ; Meggy, Alun (UKDRI@ Cardiff. School of Medicine. Cardiff University) ; Mehrabian, Shima (Clinic of Neurology. UH 'Alexandrovska'. Medical University - Sofia) ; Mendoza, Silvia (Instituto Andaluz de Neurociencia) ; Menéndez-González, Manuel (Servicio de Neurología. Hospital Universitario Central de Asturias- Oviedo and Instituto de Investigación Biosanitaria del Principado de Asturias) ; Mir, Pablo (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Moebus, Susanne (Institute for Urban Public Health. University Hospital of University Duisburg-Essen) ; Mol, Merel (Department of Neurology. Erasmus MC) ; Molina-Porcel, Laura (Alzheimer's Disease and Other Cognitive Disorders Unit. Neurology Department. Hospital Clinic) ; Montrreal, Laura (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Morelli, Laura (Laboratory of Brain Aging and Neurodegeneration. FIL-CONICET) ; Moreno, Fermin (Department of Neurology. Hospital Universitario Donostia. OSAKIDETZA-Servicio Vasco de Salud) ; Morgan, Kevin (Human Genetics. School of Life Sciences. University of Nottingham) ; Mosley, Thomas (Memory Impairment and Neurodegenerative Dementia (MIND) Center. University of Mississippi Medical Center) ; Nöthen, Markus M. (Institute of Human Genetics. University of Bonn. School of Medicine & University Hospital Bonn) ; Muchnik, Carolina (Instituto de Investigaciones Médicas Alfredo Lanari (Buenos Aires, Argentina)) ; Mukherjee, Shubhabrata (Department of Medicine. University of Washington) ; Nacmias, Benedetta (IRCCS Fondazione Don Carlo Gnocchi) ; Ngandu, Tiia (Public Health Promotion Unit. Finnish Institute for Health and Welfare) ; Nicolas, Gael (Department of Genetics and CNR-MAJ. Normandie University. UNIROUEN. INSERM U1245. CHU Rouen) ; Nordestgaard, Børge G. (Department of Clinical Medicine. University of Copenhagen) ; Olaso, Robert (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Orellana, Adelina (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Orsini, Michela (Department of Neuroscience. Catholic University of Sacred Heart. Fondazione Policlinico Universitario A. Gemelli IRCCS) ; Ortega, Gemma (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Padovani, Alessandro (Human Genome Sequencing Center. Baylor College of Medicine) ; Paolo, Caffarra (DIMEC. University of Parma) ; Papenberg, Goran (Aging Research Center. Department of Neurobiology. Care Sciences and Society. Karolinska Institutet and Stockholm University) ; Parnetti, Lucilla (Centre for Memory Disturbances. Lab of Clinical Neurochemistry. Section of Neurology. University of Perugia) ; Pasquier, Florence (Resources and Research Memory Center (MRRC) of Distalz. LicendUniversity of Lille. INSERM. CHU Lille. UMR1172) ; Pastor, Pau (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ; Peloso, Gina (Boston University and the NHLBI's Framingham Heart Study) ; Pérez-Cordón, Alba (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Pérez-Tur, Jordi (Unitat Mixta de de Neurología y Genética. Institut d'Investigació Sanitària La Fe) ; Pericard, Pierre (US 41-UMS 2014-PLBS. bilille. Université de Lille. CNRS. INSERM. CHU Lille. Institut Pasteur de Lille) ; Peters, Oliver (German Center for Neurodegenerative Diseases (DZNE)) ; Pijnenburg, Yolande A.L. (Alzheimer Center Amsterdam. Department of Neurology. Amsterdam Neuroscience. Vrije Universiteit Amsterdam. Amsterdam UMC) ; Pineda, Juan A. (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; Piñol-Ripoll, Gerard (Institut de Recerca Biomedica de Lleida (IRBLLeida)) ; Pisanu, Claudia (Department of Biomedical Sciences. University of Cagliari) ; Polak, Thomas (Department of Psychiatry. Psychosomatics and Psychotherapy. Center of Mental Health. University Hospital) ; Popp, Julius (Department of Geriatric Psychiatry. University Hospital of Psychiatry Zürich) ; Posthuma, Danielle (Department of Complex Trait Genetics. Center for Neurogenomics and Cognitive Research. Amsterdam Neuroscience. Vrije University) ; Priller, Josef (Department of Neuropsychiatry and Laboratory of Molecular Psychiatry. Charité. Charitéplatz 1) ; Puerta, Raquel (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Quenez, Olivier (Department of Genetics and CNR-MAJ. Normandie University. UNIROUEN. INSERM U1245. CHU Rouen) ; Quintela, Inés (Grupo de Medicina Xenómica. Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII). Universidade de Santiago de Compostela) ; Thomassen, Jesper Qvist (Department of Clinical Biochemistry. Rigshospitalet) ; Rábano, Alberto (CIEN Foundation/Queen Sofia Foundation Alzheimer Center) ; Rainero, Innocenzo (Centre for Neurodegenerative Disorders. Department of Clinical and Experimental Sciences. University of Brescia) ; Rajabli, Farid (The John P. Hussman Institute for Human Genomics. University of Miami) ; Ramakers, Inez (Department of Psychiatry & Neuropsychologie. Maastricht University. Alzheimer Center Limburg) ; Real, Luis M. (Depatamento de Especialidades Quirúrgicas Bioquímica e Inmunología. Facultad de Medicina. Universidad de Málaga) ; Reinders, Marcel J.T. (Delft Bioinformatics Lab. Delft University of Technology) ; Reitz, Christiane (Taub Institute. Columbia University) ; Reyes-Dumeyer, Dolly (Taub Institute. Columbia University) ; Ridge, Perry (Bioinformatics. College of Life Sciences. Brigham Young University) ; Riedel-Heller, Steffi (Institute of Social Medicine. Occupational Health and Public Health. University of Leipzig) ; Riederer, Peter (Center of Mental Health. Clinic and Policlinic of Psychiatry. Psychosomatics and Psychotherapy. University Hospital of Würzburg) ; Roberto, Natalia (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Rodriguez-Rodriguez, Eloy (Instituto de Investigación Sanitaria Valdecilla (Santander, País Basc)) ; Rongve, Arvid (Institute of Clinical Medicine (K1). The University of Bergen) ; Rosas Allende, Irene (Servicio de Neurología. Hospital Universitario Central de Asturias- Oviedo and Instituto de Investigación Biosanitaria del Principado de Asturias) ; Rosende-Roca, Maitée (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Royo, Jose Luis (Departamento de Especialidades Quirúrgicas. Bioquímicas e Inmunología. School of Medicine. University of Málaga) ; Rubino, Elisa (Department of Neuroscience and Mental Health. AOU Città della Salute e della Scienza di Torino) ; Rujescu, Dan (Department of Psychiatry and Psychotherapy. Medical University of Vienna) ; Sáez, María Eugenia (CAEBI. Centro Andaluz de Estudios Bioinformáticos) ; Sakka, Paraskevi (Athens Association of Alzheimer's Disease and Related Disorders) ; Saltvedt, Ingvild (Department of Geriatrics. St. Olav's Hospital. Trondheim University Hospital) ; Sanabria, Ángela (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Sánchez-Arjona, Maria B. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Sanchez-Garcia, Florentino (Department of Immunology. Hospital Universitario Doctor Negrín. Las Palmas de Gran Canaria) ; Sánchez Juan, Pacual (Instituto de Investigación Sanitaria Valdecilla (Santander, País Basc)) ; Sánchez-Valle, Raquel (Neurology Department-Hospital Clínic. IDIBAPS. Universitat de Barcelona) ; Sando, Sigrid B. (Department of Neurology and Clinical Neurophysiology. University Hospital of Trondheim) ; Sarnowski, Chloé (Human Genetics Center. School of Public Health. University of Texas Health Science Center at Houston) ; Satizabal, Claudia L. (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Scamosci, Michela (Institute of Gerontology and Geriatrics. Department of Medicine and Surgery. University of Perugia) ; Scarmeas, Nikolaos (First Department of Neurology. Aiginition Hospital. National and Kapodistrian University of Athens. Medical School) ; Scarpini, Elio (University of Milan) ; Scheltens, Philip (Alzheimer Center Amsterdam. Department of Neurology. Amsterdam Neuroscience. Vrije Universiteit Amsterdam. Amsterdam UMC) ; Scherbaum, Norbert (LVR-Hospital Essen. Department of Psychiatry and Psychotherapy. Medical Faculty. University of Duisburg-Essen) ; Scherer, Martin (Department of Primary Medical Care. University Medical Centre Hamburg-Eppendorf) ; Schmid, Matthias (Institute of Medical Biometry. Informatics and Epidemiology. University Hospital of Bonn) ; Schneider, Anja (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Schott, Jonathan M. (Dementia Research Centre. UCL Queen Square Institute of Neurology) ; Selbæk, Geir (Department of Geriatric Medicine. Oslo University Hospital) ; Seripa, Davide (Laboratory for Advanced Hematological Diagnostics. Department of Hematology and Stem Cell Transplant. Vito Fazzi Hospital) ; Serrano, Manuel (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas. CIBERDEM. Hospital Clínico San Carlos) ; Sha, Jin (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Shadrin, Alexey A. (NORMENT Centre. University of Oslo) ; Skrobot, Olivia (Translational Health Sciences. Bristol Medical School. University of Bristol) ; Slifer, Susan H. (The John P. Hussman Institute for Human Genomics. University of Miami) ; Snijders, Gijsje J.L. (Department of Psychiatry. Icahn School of Medicine at Mount Sinai) ; Soininen, Hilkka (Institute of Clinical Medicine. Neurology. University of Eastern) ; Solfrizzi, Vincenzo (University of Bari. "A. Moro") ; Solomon, Alina (Division of Clinical Geriatrics. Center for Alzheimer Research. Care Sciences and Society (NVS). Karolinska Institutet) ; Song, Yeunjoo (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Sorbi, Sandro (IRCCS Fondazione Don Carlo Gnocchi) ; Sotolongo Grau, Oscar (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Spalletta, Gianfranco (Laboratory of Neuropsychiatry. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Spottke, Annika (Department of Neurology. University of Bonn) ; Squassina, Alessio (Department of Biomedical Sciences. Section of Neuroscience and Clinical Pharmacology. University of Cagliari) ; Stordal, Eystein (Department of Psychiatry. Namsos Hospital) ; Tartan, Juan Pablo (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Tárraga, Lluís (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Tesí, Niccolo (Section Genomics of Neurodegenerative Diseases and Aging. Department of Human Genetics Amsterdam UMC. Vrije Universiteit Amsterdam. Amsterdam UMC) ; Thalamuthu, Anbupalam (Centre for Healthy Brain Ageing. School of Psychiatry. Faculty of Medicine. University of New South Wales) ; Thomas, Tegos (Alzheimer Hellas) ; Tosto, Giuseppe (Department of Neurology. Columbia University) ; Traykov, Latchezar (Clinic of Neurology. UH 'Alexandrovska'. Medical University - Sofia) ; Tremolizzo, Lucio (Neurology Unit. San Gerardo Hospital) ; Tybjærg-Hansen, Anne (Department of Clinical Biochemistry. Rigshospitalet) ; Uitterlinden, Andre (Department of Internal Medicine and Biostatistics. Erasmus MC) ; Ullgren, Abbe (Center for Alzheimer Research. Department NVS. Division of Neurogeriatrics. Karolinska Institutet) ; Ulstein, Ingun (Department of Geriatric Medicine. Oslo University Hospital) ; Valero, Sergi (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Valladares, Otto (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; Van Broeckhoven, Christine (Neurodegenerative Brain Diseases Group. VIB Center for Molecular Neurology. VIB) ; Vance, Jeffery (Dr. John T. Macdonald Foundation Department of Human Genetics. University of Miami) ; Vardarajan, Badri N. (Taub Institute on Alzheimer's Disease and the Aging Brain. Department of Neurology. Columbia University) ; van der Lugt, Aad (Department of Neurology. ErasmusMC) ; Van Dongen, Jasper (Department of Biomedical Sciences. University of Antwerp) ; van Rooij, Jeroen (Department of Neurology. ErasmusMC) ; van Swieten, John (Department of Neurology. Erasmus MC) ; Vandenberghe, Rik (Neurology Department. University Hospitals Leuven) ; Verhey, Frans (Department of Psychiatry & Neuropsychologie. Maastricht University. Alzheimer Center Limburg) ; Vidal, Jean-Sébastien (EA 4468. Université de Paris. APHP. Hôpital Broca) ; Vogelgsang, Jonathan (Department of Psychiatry. Harvard Medical School. McLean Hospital) ; Vyhnalek, Martin (International Clinical Research Center. St. Anne's University Hospital Brno) ; Wagner, Michael (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Wallon, David (Department of Neurology and CNR-MAJ. F 76000. Normandy Center for Genomic and Personalized Medicine. Normandie University. UNIROUEN. INSERM U1245. CHU Rouen) ; Wang, Li-San (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; Wang, Ruiqi (Department of Biostatistics. Boston University School of Public Health) ; Weinhold, Leonie (Institute of Medical Biometry. Informatics and Epidemiology. University Hospital of Bonn) ; Wiltfang, Jens (Medical Science Department. iBiMED) ; Windle, Gill (School of Health Sciences. Bangor University) ; Woods, Bob (School of Health Sciences. Bangor University) ; Yannakoulia, Mary (Department of Nutrition and Diatetics. Harokopio University) ; Zare, Habil (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Zhao, Yi (Laboratory of Neuropsychiatry. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Zhang, Xiaoling (Department of Medicine (Biomedical Genetics). Boston University School of Medicine) ; Zhu, Congcong (Department of Medicine (Biomedical Genetics). Boston University School of Medicine) ; Zulaica, Miren (Neurosciences Area. Instituto Biodonostia) ; Laczo, Jan (International Clinical Research Center. St. Anne's University Hospital Brno) ; Matoska, Vaclav (Department of Clinical Biochemistry. Hematology and Immunology. Na Homolce Hospital) ; Serpente, Maria (University of Milan) ; Assogna, Francesca (Laboratory of Neuropsychiatry. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Piras, Fabrizio (Laboratory of Neuropsychiatry. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Ciullo, Valentina (Laboratory of Neuropsychiatry. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Shofany, Jacob (Laboratory of Neuropsychiatry. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Ferrarese, Carlo (Neurology Unit. San Gerardo Hospital) ; Andreoni, Simona (School of Medicine and Surgery. University of Milano-Bicocca) ; Sala, Gessica (School of Medicine and Surgery. University of Milano-Bicocca) ; Zoia, Chiara Paola (School of Medicine and Surgery. University of Milano-Bicocca) ; Zompo, Maria del (Department of Biomedical Sciences. Section of Neuroscience and Clinical Pharmacology. University of Cagliari) ; Benussi, Alberto (Centre for Neurodegenerative Disorders. Department of Clinical and Experimental Sciences. University of Brescia) ; Bastiani, Patrizia (Institute of Gerontology and Geriatrics. Department of Medicine. University of Perugia) ; Takalo, Mari (Insitute of Biomedicine. University of Eastern Finland) ; Natunen, Teemu (Insitute of Biomedicine. University of Eastern Finland) ; Laatikainen, Tiina (Public Health Promotion Unit. Finnish Institute for Health and Welfare) ; Tuomilehto, Jaakko (Public Health Promotion Unit. Finnish Institute for Health and Welfare) ; Antikainen, Riitta (Medical Research Center Oulu. Oulu University Hospital) ; Strandberg, Timo (Helsinki University Hospital) ; Lindström, Jaana (Public Health Promotion Unit. Finnish Institute for Health and Welfare) ; Peltonen, Markku (Public Health Promotion Unit. Finnish Institute for Health and Welfare) ; Abraham, Richard (Division of Psychological Medicine and Clinial Neurosciences. MRC Centre for Neuropsychiatric Genetics and Genomics. Cardiff University) ; Al-Chalabi, Ammar (Institute of Psychiatry. Psychology and Neuroscience. Kings College London) ; Bass, Nicholas J. (Division of Psychiatry. University College London) ; Brayne, Carol (Institute of Public Health. University of Cambridge) ; Brown, Kristelle S. (Institute of Genetics. Queens Medical Centre. University of Nottingham) ; Collinge, John (MRC Prion Unit at UCL. UCL Institute of Prion Diseases) ; Craig, David (Ageing Group. Centre for Public Health. School of Medicine. Dentistry and Biomedical Sciences. Queen's University Belfast) ; Deloukas, Pangiotis (The Wellcome Trust Sanger Institute. Wellcome Trust Genome Campus. Hinxton) ; Fox, Nick (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Gerrish, Amy (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Gill, Michael (Mercer's Institute for Research on Ageing. St James' Hospital) ; Gwilliam, Rhian (The Wellcome Trust Sanger Institute. Wellcome Trust Genome Campus. Hinxton) ; Harold, Denise (School of Biotechnology. Dublin City University) ; Hollingworth, Paul (Division of Psychological Medicine and Clinial Neurosciences. MRC Centre for Neuropsychiatric Genetics and Genomics. Cardiff University) ; Johnston, Jarret A. (Centre for Public Health. School of Medicine. Dentistry and Biomedical Sciences. Queens University) ; Jones, Lesley (Division of Psychological Medicine and Clinial Neurosciences. MRC Centre for Neuropsychiatric Genetics and Genomics. Cardiff University) ; Lawlor, Brian (Mercer's Institute for Research on Ageing. St James' Hospital) ; Livingston, Gill (Division of Psychiatry. University College London) ; Lovestone, Simon (Department of Psychiatry. University of Oxford) ; Lupton, Michelle (Department of Basic and Clinical Neuroscience. Institute of Psychiatry. Psychology and Neuroscience. Kings College London) ; Lynch, Aoibhinn (Mercer's Institute for Research on Ageing. St James' Hospital) ; Mann, David (Division of Neuroscience and Experimental Psychology. School of Biological Sciences. Faculty of Biology. Medicine and Health. University of Manchester. Manchester Academic Health Science Centre) ; McGuinness, Bernadette (Centre for Public Health. School of Medicine. Dentistry and Biomedical Sciences. Queens University) ; McQuillin, Andrew (Division of Psychiatry. University College London) ; O'Donovan, Michael C. (Division of Psychological Medicine and Clinial Neurosciences. MRC Centre for Neuropsychiatric Genetics and Genomics. Cardiff University) ; Owen, Michael J. (Division of Psychological Medicine and Clinial Neurosciences. MRC Centre for Neuropsychiatric Genetics and Genomics. Cardiff University) ; Passmore, Peter (Centre for Public Health. School of Medicine. Dentistry and Biomedical Sciences. Queens University) ; Powell, John F. (Department of Basic and Clinical Neuroscience. Institute of Psychiatry. Psychology and Neuroscience. Kings College London) ; Proitsi, Petra (Department of Basic and Clinical Neuroscience. Institute of Psychiatry. Psychology and Neuroscience. Kings College London) ; Rossor, Martin (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Shaw, Christopher E. (Institute of Psychiatry. Psychology and Neuroscience. Kings College London) ; Smith, A. David (Oxford Project to Investigate Memory and Ageing (OPTIMA). University of Oxford. Level 4. John Radcliffe Hospital) ; Gurling, Hugh (Department of Mental Health Sciences. University College London) ; Todd, Stephen (Ageing Group. Centre for Public Health. School of Medicine. Dentistry and Biomedical Sciences. Queen's University Belfast) ; Mummery, Catherine (Dementia Research Centre. UCL) ; Ryan, Nathalie (Dementia Research Centre. UCL) ; Lacidogna, Giordano (Department of Neuroscience. Catholic University of Sacred Heart. Fondazione Policlinico Universitario A. Gemelli IRCCS) ; Adarmes-Gómez, A.D (Department of Neurology. Erasmus MC) ; Mauleón, Ana (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Pancho, Ana (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Gailhajenet, Anna (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Lafuente, Asunción (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Macias-García, D. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Martín, Elvira (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Pelejá, Esther (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Carrillo, F. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Sastre Merlín, Isabel (Centro de Biología Molecular Severo Ochoa (UAM-CSIC)) ; Garrote-Espina, L. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Vargas, Liliana (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Carrión-Claro, M. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Marín, M. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Labrador, Ma (Department of Neurology. Erasmus MC) ; Buendia, Mar (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Alonso, María Dolores (Servei de Neurologia. Hospital Clínic Universitari de València) ; Guitart, Marina (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Moreno, Mariona (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Ibarria, Marta (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Periñán, Mt (Department of Neurology. Erasmus MC) ; Aguilera, Nuria (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Gómez-Garre, P. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Cañabate, Pilar (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Escuela, R. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Pineda-Sánchez, R. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Vigo-Ortega, R. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Jesús, S. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Preckler, S. (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Rodrigo-Herrero, S. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Diego, Susana (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Vacca, Alessandro (Department of Neuroscience "Rita Levi Montalcini". University of Torino) ; Roveta, F. (Department of Neuroscience "Rita Levi Montalcini". University of Torino) ; Salvadori, N. (Institute of Cognitive Neurology and Dementia Research (IKND). Otto-Von-Guericke University) ; Chipi, E. (Institute of Cognitive Neurology and Dementia Research (IKND). Otto-Von-Guericke University) ; Boecker, H. (Department of Radiology. University Hospital Bonn) ; Laske, C. (Section for Dementia Research. Department of Psychiatry. Hertie Institute for Clinical Brain Research) ; Perneczky, R. (Department of Psychiatry and Psychotherapy. University Hospital. LMU Munich) ; Anastasiou, C. (Department of Nutrition and Diatetics. Harokopio University) ; Janowitz, D. (Institute for Stroke and Dementia Research. Klinikum der Universität München. Ludwig Maximilians Universität (LMU)) ; Malik, R. (Institute for Stroke and Dementia Research. Klinikum der Universität München. Ludwig Maximilians Universität (LMU)) ; Anastasiou, A. (First Department of Neurology. Medical School. Aristotle University of Thessaloniki) ; Parveen, K. (Department of Neurodegenerative Diseases and Geriatric Psychiatry. University Hospital Bonn) ; Lage, C. (Service of Neurology. University Hospital Marqués de Valdecilla. IDIVAL. University of Cantabria) ; López-García, S. (Service of Neurology. University Hospital Marqués de Valdecilla. IDIVAL. University of Cantabria) ; Antonell, A. (Neurology Department-Hospital Clínic. IDIBAPS. Universitat de Barcelona) ; Mihova, K.Y. (Molecular Medicine Center. Department of Medical chemistry and biochemistry. Medical University of Sofia) ; Belezhanska, D. (Clinic of Neurology. UH 'Alexandrovska'. Medical University - Sofia) ; Weber, H. (Department of Psychiatry. Psychosomatics and Psychotherapy. Center of Mental Health. University Hospital of Würzburg) ; Kochen, S. (ENYS (Estudio en Neurociencias y Sistemas Complejos) CONICET- Hospital El Cruce "Nestor Kirchner"- UNAJ) ; Solis, P. (ENYS (Estudio en Neurociencias y Sistemas Complejos) CONICET- Hospital El Cruce "Nestor Kirchner"- UNAJ) ; Medel, N. (ENYS (Estudio en Neurociencias y Sistemas Complejos) CONICET- Hospital El Cruce "Nestor Kirchner"- UNAJ) ; Lisso, J. (ENYS (Estudio en Neurociencias y Sistemas Complejos) CONICET- Hospital El Cruce "Nestor Kirchner"- UNAJ) ; Sevillano, Z. (ENYS (Estudio en Neurociencias y Sistemas Complejos) CONICET- Hospital El Cruce "Nestor Kirchner"- UNAJ) ; Politis, D.G. (HIGA Eva Perón) ; Cores, V. (HIGA Eva Perón) ; Cuesta, C. (HIGA Eva Perón) ; Ortiz, C. (Neurología Clinica) ; Bacha, J.I. (Neurología Clinica) ; Rios, M. (Dirección de Atención de Adultos Mayores del Min. Salud Desarrollo Social y Deportes de la Pcia. de Mendoza) ; Saenz, A. (Dirección de Atención de Adultos Mayores del Min. Salud Desarrollo Social y Deportes de la Pcia. de Mendoza) ; Abalos, M.S. (Laboratorio de Genética Forense del Ministerio Público de la Pcia de La Pampa) ; Kohler, E. (Fundacion Sinapsis) ; Palacio, D.L. (Hospital Dr. Lucio Molas. Santa Rosa; Fundacion Ayuda Enfermo Renal y Alta Complejidad (FERNAC)) ; Etchepareborda, I. (Hospital Dr. Lucio Molas. Santa Rosa; Fundacion Ayuda Enfermo Renal y Alta Complejidad (FERNAC)) ; Kohler, M. (Hospital Dr. Lucio Molas. Santa Rosa; Fundacion Ayuda Enfermo Renal y Alta Complejidad (FERNAC)) ; Novack, G. (Laboratory of Brain Aging and Neurodegeneration (FIL)) ; Prestia, F.A. (Laboratory of Brain Aging and Neurodegeneration (FIL)) ; Galeano, P. (Laboratory of Brain Aging and Neurodegeneration (FIL)) ; Castaño, E.M. (Laboratory of Brain Aging and Neurodegeneration (FIL)) ; Germani, S. (Centro de Neuropsiquiatría y Neurología de la Conducta (CENECON). Facultad de Medicina. Universidad de Buenos Aires (UBA). C.A.B.A.) ; Toso, C.R. (Centro de Neuropsiquiatría y Neurología de la Conducta (CENECON). Facultad de Medicina. Universidad de Buenos Aires (UBA). C.A.B.A.) ; Rojo, M. (Centro de Neuropsiquiatría y Neurología de la Conducta (CENECON). Facultad de Medicina. Universidad de Buenos Aires (UBA). C.A.B.A.) ; Ingino, C. (Centro de Neuropsiquiatría y Neurología de la Conducta (CENECON). Facultad de Medicina. Universidad de Buenos Aires (UBA). C.A.B.A.) ; Mangone, C. (Centro de Neuropsiquiatría y Neurología de la Conducta (CENECON). Facultad de Medicina. Universidad de Buenos Aires (UBA). C.A.B.A.) ; Rubinsztein, D.C. (Cambridge Institute for Medical Research and UK Dementia Research Institute. University of Cambridge) ; Teipel, S. (German Center for Neurodegenerative Diseases (DZNE)) ; Fievet, N. (Université de Lille. INSERM. CHU Lille. Institut Pasteur Lille. U1167-RID-AGE. Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Deramerourt, V. (Resources and Research Memory Center (MRRC) of Distalz. LicendUniversity of Lille. INSERM. CHU Lille. UMR1172) ; Forsell, C. (Unit for Hereditary Dementias. Karolinska University Hospital-Solna) ; Thonberg, H. (Unit for Hereditary Dementias. Karolinska University Hospital-Solna) ; Bjerke, M. (Grupo de Medicina Xenómica. Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII). Universidade de Santiago de Compostela) ; Roeck, E.D. (Grupo de Medicina Xenómica. Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII). Universidade de Santiago de Compostela) ; Martínez-Larrad, M.T. (Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas. CIBERDEM. Hospital Clínico San Carlos) ; Olivar, N. (Centro de Neuropsiquiatría y Neurología de la Conducta (CENECON). Facultad de Medicina. Universidad de Buenos Aires (UBA). C.A.B.A.) ; Aguilera, N. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Cano, A. (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Cañabate, P. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Macias, J. (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ; Maroñas, O. (Grupo de Medicina Xen'omica. Centro Nacional de Genotipado (CEGEN-PRB3-ISCIII). Universidad de Santiago de Compostela) ; Nuñez-Llaves, R. (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Olivé, C. (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Pelejá, E. (Research Center and Memory Clinic Fundació ACE. Institut Català de Neurociències Aplicades. Universitat Internacional de Catalunya) ; Adarmes-Gómez, A.D (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Alonso, M.D. (Servei de Neurologia. Hospital Clínic Universitari de València) ; Amer-Ferrer, G. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ; Antequera, M. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; Burguera, J.A. (Hospital Universitari i Politècnic La Fe (València)) ; Carrillo, F. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Carrión-Claro, M. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Casajeros, M.J. (Hospital Universitario Ramón y Cajal (Madrid)) ; Martinez de Pancorbo, M. (BIOMICs. País Vasco; Centro de Investigación Lascaray. Universidad del País Vasco UPV/EHU) ; Escuela, R. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Garrote-Espina, L. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Gómez-Garre, P. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Hevilla, S. (Instituto Andaluz de Neurociencia) ; Jesús, S. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Espinosa, M.A.L. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Legaz, A. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; López-García, S. (Service of Neurology. University Hospital Marqués de Valdecilla. IDIVAL. University of Cantabria) ; Macias-García, D. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Manzanares, S. (Fundación para la Formación e Investigación Sanitarias de la Región de Murcia) ; Marín, M. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Marín-Muñoz, J. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; Marín, T. (Instituto Andaluz de Neurociencia) ; Martínez, B. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; Martínez, V. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; Martínez-Lage Álvarez, P. (Centro de Investigación y Terapias Avanzadas. Fundación CITA-Alzheimer) ; Iriarte, M.M. (Navarrabiomed) ; Periñán-Tocino, M.T. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Pineda-Sánchez, R. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Real de Asúa, D. (Hospital Universitario de la Princesa (Madrid)) ; Rodrigo, S. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ; Sastre, I. (Centro de Biología Molecular Severo Ochoa (UAM-CSIC)) ; Vicente, M. P. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; Vigo-Ortega, R. (Unidad de Trastornos del Movimiento. Servicio de Neurología y Neurofisiología. Instituto de Biomedicina de Sevilla (IBiS). Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla) ; Vivancos, L. (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ; Epelbaum, J. (UMR 7179 CNRS/MNHN) ; Hannequin, D. (Department of Neurology and CNR-MAJ. F 76000. Normandy Center for Genomic and Personalized Medicine. Normandie University. UNIROUEN. INSERM U1245. CHU Rouen) ; campion, D. (Department of Genetics and CNR-MAJ. Normandie University. UNIROUEN. INSERM U1245. CHU Rouen) ; Deramecourt, V. (Resources and Research Memory Center (MRRC) of Distalz. LicendUniversity of Lille. INSERM. CHU Lille. UMR1172) ; Tzourio, C. (Bordeaux Population Health Research Center. University Bordeaux. INSERM) ; Brice, A. (Sorbonne Université. Paris Brain Institute. APHP. INSERM. CNRS) ; Dubois, B. (Department of Neurology. Institute of Memory and Alzheimer's Disease (IM2A). Pitié-Salpêtrière Hospital. AP-HP. Boulevard de l'Hôpital) ; Williams, A. (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Thomas, C. (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Davies, C. (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Nash, W. (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Dowzell, K. (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; Morales, A.C. (UKDRI@ Cardiff. School of Medicine. Cardiff University) ; Bernardo-Harrington, M. (UKDRI@ Cardiff. School of Medicine. Cardiff University) ; Turton, J. (Institute of Genetics. Queen's Medical Centre. University of Nottingham) ; Lord, J. (Institute of Genetics. Queen's Medical Centre. University of Nottingham) ; Brown, K. (Institute of Genetics. Queens Medical Centre. University of Nottingham) ; Vardy, E. (Institute for Ageing and Health. Newcastle University. Campus for Ageing and Vitality) ; Fisher, E. (Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Warren, J.D. (Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Rossor, M. (Dementia Research Centre. Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Ryan, N.S. (Dementia Research Centre. UCL) ; Guerreiro, R. (Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Uphill, J. (MRC Prion Unit at UCL. UCL Institute of Prion Diseases) ; Bass, N. (Division of Psychiatry. University College London) ; Heun, R. (Department of Old Age Psychiatry. Institute of Psychiatry. Psychology and Neuroscience. King's College London) ; Kölsch, H. (Department of Psychiatry and Psychotherapy. University of Bonn) ; Schürmann, B. (Department of Psychiatry and Psychotherapy. University of Bonn) ; Lacour, A. (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Herold, C. (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Johnston, J.A. (Centre for Public Health. School of Medicine. Dentistry and Biomedical Sciences. Queens University) ; Passmore, P. (Centre for Public Health. School of Medicine. Dentistry and Biomedical Sciences. Queens University) ; Powell, J. (Department of Basic and Clinical Neuroscience. Institute of Psychiatry. Psychology and Neuroscience. Kings College London) ; Patel, Y. (University of Toronto) ; Hodges, A. (Department of Old Age Psychiatry. Institute of Psychiatry. Psychology and Neuroscience. King's College London) ; Becker, T. (Institute for Medical Biometry. Informatics and Epidemiology. University of Bonn) ; Warden, D. (Oxford Project to Investigate Memory and Ageing (OPTIMA). University of Oxford. Level 4. John Radcliffe Hospital) ; Wilcock, G. (Oxford Project to Investigate Memory and Ageing (OPTIMA). University of Oxford. Level 4. John Radcliffe Hospital) ; Clarke, R. (Department of Neurodegenerative Disease. UCL Institute of Neurology) ; Deloukas, P. (The Wellcome Trust Sanger Institute. Wellcome Trust Genome Campus. Hinxton) ; Ben-Shlomo, Y. (Population Health Sciences. Bristol Medical School. University of Bristol) ; Hooper, N.M. (Division of Neuroscience and Experimental Psychology. School of Biological Sciences. Faculty of Biology. Medicine and Health. University of Manchester. Manchester Academic Health Science Centre) ; Pickering-Brown, S. (University of Manchester. Manchester Academic Health Science Centre) ; Sussams, R. (Division of Clinical Neurosciences. School of Medicine. University of Southampton) ; Warner, N. (Somerset Partnership NHS Trust) ; Bayer, A. (Institute of Primary Care and Public Health. Cardiff University. University Hospital of Wales) ; Heuser, I. (Department of Psychiatry and Psychotherapy. Charité University Medicine) ; Drichel, D. (Universität zu Köln (Colònia, Alemaya). Cologne Center for Genomics) ; Klopp, N. (Institute of Epidemiology. Helmholtz Zentrum München. German Research Center for Environmental Health. Neuherberg) ; Mayhaus, M. (Department of Psychiatry and Psychotherapy. University Hospital) ; Riemenschneider, M. (Department of Psychiatry and Psychotherapy. University Hospital) ; Pinchler, S. (Department of Psychiatry and Psychotherapy. University Hospital) ; Feulner, T. (Department of Psychiatry and Psychotherapy. University Hospital) ; Gu, W. (Department of Psychiatry and Psychotherapy. University Hospital) ; van den Bussche, H. (Department of Primary Medical Care. University Medical Centre Hamburg-Eppendorf) ; Hüll, M. (Department of Psychiatry. University of Freiburg) ; Frölich, L. (Central Institute of Mental Health. Medical Faculty Mannheim. University of Heidelberg) ; Wichmann, H.E. (Institute of Epidemiology. Helmholtz Zentrum München. German Research Center for Environmental Health. Neuherberg) ; Jöckel, K.H. (Institute for Medical Informatics. Biometry and Epidemiology. University Hospital of Essen. University Duisburg-Essen) ; O'Donovan, M. (Division of Psychological Medicine and Clinial Neurosciences. MRC Centre for Neuropsychiatric Genetics and Genomics. Cardiff University) ; Owen, M. (Division of Psychological Medicine and Clinial Neurosciences. MRC Centre for Neuropsychiatric Genetics and Genomics. Cardiff University) ; Bahrami, S. (Division of Mental Health and Addiction. Oslo University Hospital) ; Bosnes, I. (Department of Psychiatry. Hospital Namsos. Nord-Trøndelag Health Trust) ; Selnes, P. (Department of Neurology. Akershus University Hospital) ; Bergh, S. (Centre for Old Age Psychiatry Research. Innlandet Hospital Trust) ; Palotie, A. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Daly, M. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Jacob, H. (AbbVie) ; Matakidou, A. (Astra Zeneca) ; Runz, H. (Biogen) ; John, S. (Biogen) ; Plenge, R. (Celgene) ; McCarthy, M. (Genentech) ; Hunkapiller, J. (Genentech) ; Ehm, M. (GlaxoSmithKline) ; Waterworth, D. (GlaxoSmithKline) ; Fox, C. (Merck) ; Malarstig, A. (Pfizer) ; Klinger, K. (Sanofi) ; Call, K. (Sanofi) ; Behrens, T. (Maze Therapeutics) ; Loerch, P. (Janssen Biotech) ; Mäkelä, T. (HiLIFE. University of Helsinki) ; Kaprio, Jaakko (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Virolainen, P. (Auria Biobank. University of Turku. Hospital District of Southwest Finland) ; Pulkki, K. (Auria Biobank. University of Turku. Hospital District of Southwest Finland) ; Kilpi, T. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Perola, M. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Partanen, J. (Finnish Red Cross Blood Service. Finnish Hematology Registry and Clinical Biobank) ; Pitkäranta, A. (Helsinki Biobank. Helsinki University and Hospital District of Helsinki and Uusimaa) ; Kaarteenaho, R. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Vainio, S. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Turpeinen, M. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Serpi, R. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Laitinen, T. (Oxford Healthy Aging Project. Clinical Trial Service Unit. University of Oxford) ; Mäkelä, J. (Finnish Clinical Biobank Tampere. University of Tampere. Pirkanmaa Hospital District) ; Kosma, V.M. (Biobank of Eastern Finland. University of Eastern Finland / Northern Savo Hospital District) ; Kujala, U. (Central Finland Biobank. University of Jyväskylä. Central Finland Health Care District) ; Tuovila, O. (Business Finland) ; Hendolin, M. (Business Finland) ; Pakkanen, R. (Business Finland) ; Waring, J. (AbbVie) ; Riley-Gillis, B. (AbbVie) ; Liu, J. (Biogen) ; Biswas, S. (Celgene) ; Diogo, D. (Merck) ; Marshall, C. (Pfizer) ; Hu, X. (Pfizer) ; Gossel, M. (Sanofi) ; Graham, R. (Maze Therapeutics) ; Cummings, B. (Janssen Biotech) ; Ripatti, Samuli (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Schleutker, J. (Auria Biobank. University of Turku. Hospital District of Southwest Finland) ; Arvas, M. (Finnish Red Cross Blood Service. Finnish Hematology Registry and Clinical Biobank) ; Carpén, O. (Helsinki Biobank. Helsinki University and Hospital District of Helsinki and Uusimaa) ; Hinttala, R. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Kettunen, J. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Mannermaa, A. (Biobank of Eastern Finland. University of Eastern Finland / Northern Savo Hospital District) ; Laukkanen, J. (Central Finland Biobank. University of Jyväskylä. Central Finland Health Care District) ; Julkunen, V. (Northern Savo Hospital District) ; Remes, A. (Northern Savo Hospital District) ; Kälviäinen, R. (Northern Savo Hospital District) ; Peltola, J. (Pirkanmaa Hospital District) ; Tienari, P. (Hospital District of Helsinki and Uusimaa) ; Rinne, J. (Hospital District of Southwest Finland) ; Ziemann, A. (AbbVie) ; Waring, J. (AbbVie) ; Esmaeeli, S. (AbbVie) ; Smaoui, N. (AbbVie) ; Lehtonen, A. (AbbVie) ; Eaton, S. (Biogen) ; Lahdenperä, S. (Biogen) ; van Adelsberg, J. (Celgene) ; Michon, J. (Genentech) ; Kerchner, G. (Genentech) ; Bowers, N. (Genentech) ; Teng, E. (Genentech) ; Eicher, J. (Genentech) ; Mehta, V. (Merck) ; Gormley, P. (Merck) ; Linden, K. (Pfizer) ; Whelan, C. (Pfizer) ; Xu, F. (GlaxoSmithKline) ; Pulford, D. (GlaxoSmithKline) ; Färkkilä, M. (Hospital District of Helsinki and Uusimaa) ; Pikkarainen, S. (Hospital District of Helsinki and Uusimaa) ; Jussila, A. (Pirkanmaa Hospital District) ; Blomster, T. (Northern Ostrobothnia Hospital District) ; Kiviniemi, M. (Northern Savo Hospital District) ; Voutilainen, M. (Hospital District of Southwest Finland) ; Georgantas, B. (AbbVie) ; Heap, G. (AbbVie) ; Rahimov, F. (AbbVie) ; Usiskin, K. (Celgene) ; Lu, T. (Department of Complex Trait Genetics. Center for Neurogenomics and Cognitive Research. Amsterdam Neuroscience. Vrije University) ; Oh, D. (Genentech) ; Kalpala, K. (Pfizer) ; Miller, M. (Pfizer) ; McCarthy, L. (GlaxoSmithKline) ; Eklund, K. (Hospital District of Helsinki and Uusimaa) ; Palomäki, A. (Hospital District of Southwest Finland) ; Isomäki, P. (Pirkanmaa Hospital District) ; Pirilä, L. (Hospital District of Southwest Finland) ; Kaipiainen-Seppänen, O. (Northern Savo Hospital District) ; Huhtakangas, J. (Northern Ostrobothnia Hospital District) ; Lertratanakul, A. (AbbVie) ; Hochfeld, M. (Celgene) ; Bing, N. (Pfizer) ; Gordillo, J.E. (GlaxoSmithKline) ; Mars, N. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Pelkonen, M. (Northern Savo Hospital District) ; Kauppi, P. (Hospital District of Helsinki and Uusimaa) ; Kankaanranta, H. (Pirkanmaa Hospital District) ; Harju, T. (Northern Ostrobothnia Hospital District) ; Close, D. (Astra Zeneca) ; Greenberg, S. (Celgene) ; Chen, H. (Genentech) ; Betts, J. (GlaxoSmithKline) ; Ghosh, S. (GlaxoSmithKline) ; Salomaa, V. (The National Institute of Health and Welfare Helsinki) ; Niiranen, T. (The National Institute of Health and Welfare Helsinki) ; Juonala, M. (Hospital District of Southwest Finland) ; Metsärinne, K. (Hospital District of Southwest Finland) ; Kähönen, M. (Pirkanmaa Hospital District) ; Junttila, J. (Northern Ostrobothnia Hospital District) ; Laakso, Markku (Northern Savo Hospital District) ; Pihlajamäki, J. (Northern Savo Hospital District) ; Sinisalo, J. (Hospital District of Helsinki and Uusimaa) ; Taskinen, M.R. (Hospital District of Helsinki and Uusimaa) ; Tuomi, T. (Hospital District of Helsinki and Uusimaa) ; Challis, B. (Astra Zeneca) ; Peterson, A. (Genentech) ; Chu, A. (Merck) ; Parkkinen, J. (Pfizer) ; Muslin, A. (Sanofi) ; Joensuu, H. (Hospital District of Helsinki and Uusimaa) ; Meretoja, T. (Hospital District of Helsinki and Uusimaa) ; Aaltonen, L. (Hospital District of Helsinki and Uusimaa) ; Mattson, J. (Hospital District of Helsinki and Uusimaa) ; Auranen, A. (Pirkanmaa Hospital District) ; Karihtala, P. (Northern Ostrobothnia Hospital District) ; Kauppila, S. (Northern Ostrobothnia Hospital District) ; Auvinen, P. (Northern Ostrobothnia Hospital District) ; Elenius, K. (Hospital District of Southwest Finland) ; Popovic, R. (AbbVie) ; Schutzman, J. (Genentech) ; Loboda, A. (Merck) ; Chhibber, A. (Merck) ; Lehtonen, H. (Pfizer) ; McDonough, S. (Pfizer Worldwide Research and Development) ; Crohns, M. (Sanofi) ; Kulkarni, D. (GlaxoSmithKline) ; Kaarniranta, K. (Northern Savo Hospital District) ; Turunen, J.A. (Hospital District of Helsinki and Uusimaa) ; Ollila, T. (Hospital District of Helsinki and Uusimaa) ; Seitsonen, S. (Hospital District of Helsinki and Uusimaa) ; Uusitalo, H. (Pirkanmaa Hospital District) ; Aaltonen, V. (Hospital District of Southwest Finland) ; Uusitalo-Järvinen, H. (Pirkanmaa Hospital District) ; Luodonpää, M. (Northern Ostrobothnia Hospital District) ; Hautala, N. (Northern Ostrobothnia Hospital District) ; Loomis, S. (Biogen) ; Strauss, E. (Genentech) ; Chen, H. (Genentech) ; Podgornaia, A. (Merck) ; Hoffman, J. (GlaxoSmithKline) ; Tasanen, K. (Northern Ostrobothnia Hospital District) ; Huilaja, L. (Northern Ostrobothnia Hospital District) ; Hannula-Jouppi, K. (Hospital District of Helsinki and Uusimaa) ; Salmi, T. (Pirkanmaa Hospital District) ; Peltonen, S. (Hospital District of Helsinki and Uusimaa) ; Koulu, L. (Hospital District of Helsinki and Uusimaa) ; Harvima, I. (Northern Savo Hospital District) ; Wu, Y. (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Choy, D. (Genentech) ; Pussinen, P. (Hospital District of Helsinki and Uusimaa) ; Salminen, A. (Hospital District of Helsinki and Uusimaa) ; Salo, T. (Hospital District of Helsinki and Uusimaa) ; Rice, D. (Hospital District of Helsinki and Uusimaa) ; Nieminen, P. (Hospital District of Helsinki and Uusimaa) ; Palotie, U. (Hospital District of Helsinki and Uusimaa) ; Siponen, M. (Northern Savo Hospital District) ; Suominen, L. (Northern Savo Hospital District) ; Mäntylä, P. (Northern Savo Hospital District) ; Gursoy, U. (Hospital District of Southwest Finland) ; Anttonen, V. (Northern Ostrobothnia Hospital District) ; Sipilä, K. (Northern Ostrobothnia Hospital District) ; Davis, J.W. (AbbVie) ; Quarless, D. (AbbVie) ; Petrovski, S. (Astra Zeneca) ; Wigmore, E. (Astra Zeneca) ; Chen, C.Y. (Biogen) ; Bronson, P. (Biogen) ; Tsai, E. (Biogen) ; Huang, Y. (Biogen) ; Maranville, J. (Celgene) ; Shaikho, E. (Celgene) ; Mohammed, E. (Celgene) ; Wadhawan, S. (Bristol Myers Squibb) ; Kvikstad, E. (Bristol Myers Squibb) ; Caliskan, M. (Bristol Myers Squibb) ; Chang, D. (Genentech) ; Bhangale, T. (Genentech) ; Pendergrass, S. (Genentech) ; Holzinger, E. (Merck) ; Chen, X. (Pfizer) ; Hedman, Å. (Pfizer) ; King, K.S. (GlaxoSmithKline) ; Wang, C. (Sanofi) ; Xu, E. (Sanofi) ; Auge, F. (Sanofi) ; Chatelain, C. (Sanofi) ; Rajpal, D. (Sanofi) ; Liu, D. (Population Health Sciences. German Center for Neurodegenerative Diseases (DZNE)) ; Call, K. (Sanofi) ; Xia, T.h. (Sanofi) ; Brauer, M. (Maze Therapeutics) ; Kurki, M. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Karjalainen, J. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Havulinna, A. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Jalanko, A. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Palta, P. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; della Briotta Parolo, P. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Zhou, W. (Broad Institute) ; Lemmelä, S. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Rivas, M. (University of Stanford) ; Harju, J. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Lehistö, A. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Ganna, A. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Llorens, V. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Laivuori, H. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Rüeger, S. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Niemi, M.E. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Tukiainen, T. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Reeve, M.P. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Heyne, H. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Palin, K. (University of Helsinki) ; Garcia-Tabuenca, J. (University of Tampere) ; Siirtola, H. (University of Tampere) ; Kiiskinen, T. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Lee, J. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Tsuo, K. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Elliott, A. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Kristiansson, K. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Hyvärinen, K. (Finnish Red Cross Blood Service) ; Ritari, J. (Finnish Red Cross Blood Service) ; Koskinen, M. (Helsinki Biobank. Helsinki University and Hospital District of Helsinki and Uusimaa) ; Pylkäs, K. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Kalaoja, M. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Karjalainen, M. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Mantere, T. (Northern Finland Biobank Borealis. University of Oulu. Northern Ostrobothnia Hospital District) ; Kangasniemi, E. (Finnish Clinical Biobank Tampere. University of Tampere. Pirkanmaa Hospital District) ; Heikkinen, S. (Biobank of Eastern Finland. University of Eastern Finland / Northern Savo Hospital District) ; Laakkonen, E. (Central Finland Biobank. University of Jyväskylä. Central Finland Health Care District) ; Sipeky, C. (University of Turku) ; Heron, S. (University of Turku) ; Karlsson, A. (Auria Biobank. University of Turku. Hospital District of Southwest Finland) ; Jambulingam, D. (University of Turku) ; Rathinakannan, V.S. (University of Turku) ; Kajanne, R. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Aavikko, M. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Jiménez, M.G. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; della Briotta Parola, P. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Lehistö, A. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Kanai, M. (Broad Institute) ; Kaunisto, M. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Kilpeläinen, E. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Sipilä, T.P. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Brein, G. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Awaisa, G. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Shcherban, A. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Donner, K. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Loukola, A. (Helsinki Biobank. Helsinki University and Hospital District of Helsinki and Uusimaa) ; Laiho, P. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Sistonen, T. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Kaiharju, E. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Laukkanen, M. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Järvensivu, E. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Lähteenmäki, S. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Männikkö, L. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Wong, R. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Mattsson, H. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Hiekkalinna, T. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Paajanen, T. (THL Biobank. The National Institute of Health and Welfare Helsinki) ; Pärn, K. (Institute for Molecular Medicine Finland. HiLIFE. University of Helsinki) ; Gracia-Tabuenca, J. (University of Tampere) ; Abner, E. (Sanders-Brown Center on Aging. Department of Epidemiology. College of Public Health. University of Kentucky) ; Adams, P.M. (Department of Psychiatry. University of Texas Southwestern Medical Center) ; Aguirre, A. (Department of Neurology. Dell Medical School. University of Texas at Austin) ; Albert, M.S. (Department of Neurology. Johns Hopkins University) ; Albin, R.L. (Michigan Alzheimer's Disease Center. University of Michigan) ; Allen, M. (Department of Neuroscience. Mayo Clinic) ; Alvarez, L. (Department of Pharmacology and Neuroscience. University of North Texas Health Science Center) ; Apostolova, L.G. (Indiana Alzheimer's Disease Research Center. Indiana University School of Medicine) ; Arnold, S.E. (Department of Psychiatry. Perelman School of Medicine. University of Pennsylvania) ; Asthana, S. (Wisconsin Alzheimer's Disease Research Center) ; Atwood, C.S. (Wisconsin Alzheimer's Disease Research Center) ; Ayres, G. (Department of Neurology. Dell Medical School. University of Texas at Austin) ; Baldwin, C.T. (Department of Medicine (Biomedical Genetics). Boston University School of Medicine) ; Barber, R.C. (Department of Pharmacology and Neuroscience. University of North Texas Health Science Center) ; Barnes, L.L. (Rush Alzheimer's Disease Center. Rush University Medical Center) ; Barral, S. (Gertrude H. Sergievsky Center. Columbia University) ; Beach, T.G. (Civin Laboratory for Neuropathology. Banner Sun Health Research Institute) ; Beecham, G.W. (The John P. Hussman Institute for Human Genomics. University of Miami) ; Beekly, D. (National Alzheimer's Coordinating Center. University of Washington) ; Below, J.E. (Human Genetics Center. Department of Epidemiology. Human Genetics. and Environmental Sciences. School of Public Health. The University of Texas Health Science Center at Houston) ; Benchek, P. (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Benitez, B.A. (Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration. Washington University School of Medicine) ; Bennett, D. (Rush Alzheimer's Disease Center. Rush University Medical Center) ; Bertelson, J. (Department of Psychiatry. University of Texas at Austin/Dell Medical School) ; Margaret, F.E. (Cognitive Neurology and Alzheimer's Disease Center. Northwestern University Feinberg School of Medicine) ; Bird, T.D. (VA Puget Sound Health Care System/GRECC) ; Blacker, D. (Department of Psychiatry. Massachusetts General Hospital/Harvard Medical School) ; Boeve, B.F. (Department of Neurology. Mayo Clinic) ; Bowen, J.D. (Swedish Medical Center) ; Boxer, A. (Department of Neurology. University of California San Francisco) ; Brewer, J. (Department of Neurosciences. University of California San Diego) ; Burke, J.R. (Department of Medicine. Duke University) ; Burns, J.M. (University of Kansas Alzheimer's Disease Center. University of Kansas Medical Center) ; Bush, W.S. (Department of Population & Quantitative Health Sciences. Case Western Reserve University) ; Buxbaum, J.D. (Nash Family Department of Neuroscience & Friedman Brain Institute. Icahn School of Medicine at Mount Sinai) ; Cairns, N.J. (Department of Pathology and Immunology. Washington University) ; Cao, C. (USF Health Byrd Alzheimer's Institute. University of South Florida) ; Carlson, C.S. (Fred Hutchinson Cancer Research Center) ; Carlsson, C.M. (Wisconsin Alzheimer's Disease Research Center) ; Carney, R.M. (Mental Health and Behavioral Science Service. Bruce W. Carter VA Medical Center) ; Carrasquillo, M.M. (Department of Neuroscience. Mayo Clinic) ; Chasse, S. (Department of Genetics. University of North Carolina at Chapel Hill) ; Chesselet, M.F. (Neurogenetics Program. University of California. Los Angeles) ; Chesi, A. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Chin, N.A. (Department of Medicine. University of Wisconsin) ; Chui, H.C. (Department of Neurology. University of Southern California) ; Craft, S. (Section of Gerontology and Geriatric Medicine Research. Wake Forest School of Medicine) ; Crane, P.K. (Department of Medicine. University of Washington) ; Cribbs, D.H. (Department of Neurology. University of California. Irvine) ; Crocco, E.A. (Department of Psychiatry and Behavioral Sciences. Miller School of Medicine. University of Miami) ; Cruchaga, C. (Department of Psychiatry. Washington University in St. Louis) ; Cullum, M. (Department of Psychiatry. University of Texas Southwestern Medical Center) ; Darby, E. (Alzheimer's Disease and Memory Disorders Center. Baylor College of Medicine) ; Davis, B. (Department of Population and Data Sciences. University of Texas Southwestern Medical Center) ; De Jager, P.L. (Center for Translational and Computational Neuroimmunology. Department of Neurology. Columbia University Medical Center) ; DeCarli, C. (Department of Neurology. University of California. Davis) ; DeToledo, J. (Departments of Neurology. Pharmacology and Neuroscience. Texas Tech University Health Science Center) ; Dick, M. (Institute for Memory Impairments and Neurological Disorders. University of California. Irvine) ; Dickson, D.W. (Department of Neuroscience. Mayo Clinic) ; Dombroski, B.A. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Doody, R.S. (Alzheimer's Disease and Memory Disorders Center. Baylor College of Medicine) ; Duara, R. (Wien Center for Alzheimer's Disease and Memory Disorders. Mount Sinai Medical Center) ; Ertekin-Taner, N. (Department of Neurology. Mayo Clinic) ; Evans, D.A. (Rush Institute for Healthy Aging. Department of Internal Medicine. Rush University Medical Center) ; Fairchild, T.J. (Office of Strategy and Measurement. University of North Texas Health Science Center) ; Fallon, K.B. (Department of Pathology. University of Alabama at Birmingham) ; Farlow, M.R. (Department of Neurology. Indiana University) ; Farrell, J.J. (Department of Medicine (Biomedical Genetics). Boston University School of Medicine) ; Fernandez-Hernandez, V. (Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration. Washington University School of Medicine) ; Ferris, S. (Department of Psychiatry. New York University) ; Frosch, M.P. (C.S. Kubik Laboratory for Neuropathology. Massachusetts General Hospital) ; Fulton-Howard, B. (Department of Neuroscience. Ronald M. Loeb Center for Alzheimer's Disease. Icahn School of Medicine at Mount Sinai) ; Galasko, D.R. (Department of Neurosciences. University of California San Diego) ; Gamboa, A. (Department of Health Management and Policy. School of Public Health. University of North Texas Health Science Center) ; Gearing, M. (Emory Alzheimer's Disease Center. Emory University) ; Geschwind, D.H. (NeuroGenomics and Informatics. Washington University in St. Louis) ; Ghetti, Bernardino (Department of Pathology and Laboratory Medicine. Indiana University) ; Gilbert, J.R. (The John P. Hussman Institute for Human Genomics. University of Miami) ; Grabowski, T.J. (Department of Radiology. University of Washington) ; Graff-Radford, N.R. (Department of Neurology. Mayo Clinic) ; Grant, S.F.A. (Department of Genetics. Perelman School of Medicine. University of Pennsylvania) ; Green, R.C. (Division of Genetics. Department of Medicine and Partners Center for Personalized Genetic Medicine. Brigham and Women's Hospital and Harvard Medical School) ; Growdon, J.H. (Department of Neurology. Massachusetts General Hospital/Harvard Medical School) ; Haines, J.L. (Department of Population & Quantitative Health Sciences. Case Western Reserve University) ; Hakonarson, H. (Division of Human Genetics. Department of Pediatrics. Perelman School of Medicine. University of Pennsylvania) ; Hall, J. (Department of Pharmacology and Neuroscience. University of North Texas Health Science Center) ; Hamilton, R.L. (Department of Pathology (Neuropathology). University of Pittsburgh) ; Harari, O. (Department of Psychiatry. Washington University in St. Louis) ; Harrell, L.E. (Department of Neurology. University of Alabama at Birmingham) ; Haut, J. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Head, E. (Department of Pathology and Laboratory Medicine. University of California Irvine) ; Henderson, V.W. (Department of Neurology and Neurological Sciences. Stanford University) ; Hernandez, M. (Departments of Neurology. Pharmacology and Neuroscience. Texas Tech University Health Science Center) ; Hohman, T. (Vanderbilt Memory and Alzheimer's Center. Department of Neurology. Vanderbilt University Medical Center) ; Honig, L.S. (Taub Institute on Alzheimer's Disease and the Aging Brain. Department of Neurology. Columbia University) ; Huebinger, R.M. (Department of Surgery. University of Texas Southwestern Medical Center) ; Huentelman, M.J. (Neurogenomics Division. Translational Genomics Research Institute) ; Hulette, C.M. (Department of Pathology. Duke University) ; Hyman, B.T. (Department of Neurology. Massachusetts General Hospital/Harvard Medical School) ; Hynan, L.S. (Department of Neurological Surgery. University of Texas Southwestern Medical Center) ; Ibanez, L. (Hope Center Program on Protein Aggregation and Neurodegeneration. Washington University School of Medicine) ; Jarvik, G.P. (Department of Genome Sciences. University of Washington) ; Jayadev, S. (Departments of Neurology and Epidemiology. University of Washington) ; Jin, L.W. (Department of Pathology and Laboratory Medicine. University of California. Davis) ; Johnson, K. (Departments of Neurology. Pharmacology and Neuroscience. Texas Tech University Health Science Center) ; Johnson, L. (Department of Health Behavior and Health Systems. University of North Texas Health Science Center) ; Kamboh, M.I. (Alzheimer's Disease Research Center. University of Pittsburgh) ; Karydas, A.M. (Department of Neurology. University of California San Francisco) ; Katz, M.J. (Department of Neurology. Albert Einstein College of Medicine) ; Kaye, J.A. (Department of Neurology. Portland Veterans Affairs Medical Center) ; Keene, C.D. (Department of Laboratory Medicine and Pathology. University of Washington) ; Khaleeq, A. (Alzheimer's Disease and Memory Disorders Center. Baylor College of Medicine) ; Kim, R. (Department of Pathology and Laboratory Medicine. University of California Irvine) ; Knebl, J. (Department of Health Behavior and Health Systems. University of North Texas Health Science Center) ; Kowall, N.W. (Department of Pathology. Boston University) ; Kramer, J.H. (Department of Neuropsychology. University of California San Francisco) ; Kuksa, P.P. (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; LaFerla, F.M. (Department of Neurobiology and Behavior. University of California Irvine) ; Lah, J.J. (Department of Neurology. Emory University) ; Larson, E.B. (Kaiser Permanente Washington Health Research Institute) ; Lee, C.Y. (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; Lee, E.B. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Lerner, A. (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Leung, Y.Y. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Leverenz, J.B. (Cleveland Clinic Lou Ruvo Center for Brain Health. Cleveland Clinic) ; Levey, A.I. (Department of Neurology. Emory University) ; Li, M. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Lieberman, A.P. (Department of Pathology. University of Michigan) ; Lipton, R.B. (Department of Neurology. Albert Einstein College of Medicine) ; Logue, M. (National Center for PTSD at Boston VA Healthcare System) ; Lyketsos, C.G. (Department of Psychiatry. Johns Hopkins University) ; Malamon, J. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Mains, D. (Department of Health Management and Policy. School of Public Health. University of North Texas Health Science Center) ; Marson, D.C. (Department of Neurology. University of Alabama at Birmingham) ; Martiniuk, F. (Department of Medicine (Pulmonary). New York University) ; Mash, D.C. (Department of Neurology. Miller School of Medicine. University of Miami) ; Masliah, E. (Department of Pathology. University of California San Diego) ; Massman, P. (Alzheimer's Disease and Memory Disorders Center. Baylor College of Medicine) ; Masurkar, A. (Department of Psychiatry. New York University) ; McCormick, W.C. (Department of Medicine. University of Washington) ; McCurry, S.M. (School of Nursing Northwest Research Group on Aging. University of Washington) ; McDavid, A.N. (Fred Hutchinson Cancer Research Center) ; McDonough, S. (Pfizer Worldwide Research and Development) ; McKee, A.C. (Department of Pathology. Boston University) ; Mesulam, M. (Cognitive Neurology and Alzheimer's Disease Center. Northwestern University Feinberg School of Medicine) ; Mez, J. (Institute of Biomedicine. University of Eastern Finland) ; Miller, B.L. (Weill Institute for Neurosciences. Memory and Aging Center. University of California. San Francisco) ; Miller, C.A. (Department of Pathology. University of Southern California) ; Miller, J.W. (Department of Pathology and Laboratory Medicine. University of California. Davis) ; Montine, T.J. (Department of Pathology. Stanford University School of Medicine) ; Monuki, E.S. (Department of Pathology and Laboratory Medicine. University of California Irvine) ; Morris, J.C. (Department of Neurology. Washington University at St. Louis) ; Myers, A.J. (Department of Psychiatry and Behavioral Sciences. Miller School of Medicine. University of Miami) ; Nguyen, T. (Department of Neurology. University of Texas Southwestern Medical Center) ; O'Bryant, S. (Institute for Translational Research. University of North Texas Health Science Center) ; Olichney, J.M. (Center for Mind and Brain and Department of Neurology. University of California. Davis) ; Ory, M. (Center for Population Health and Aging. Texas A&M University Health Science Center) ; Palmer, R. (Department of Family and Community Medicine. University of Texas Health Science Center San Antonio) ; Parisi, J.E. (Department of Laboratory Medicine and Pathology. Mayo Clinic) ; Paulson, H.L. (Michigan Alzheimer's Disease Center. University of Michigan) ; Pavlik, V. (Alzheimer's Disease and Memory Disorders Center. Baylor College of Medicine) ; Paydarfar, D. (Department of Neurology. Dell Medical School. University of Texas at Austin) ; Perez, V. (Departments of Neurology. Pharmacology and Neuroscience. Texas Tech University Health Science Center) ; Peskind, E. (Department of Psychiatry and Behavioral Sciences. University of Washington School of Medicine) ; Phillips-Cremins, J.E. (Department of Bioengineering. University of Pennsylvania) ; Pierce, A. (Department of Neurology. University of California. Irvine) ; Polk, M. (Alzheimer's Disease Center. New York University) ; Poon, W.W. (Institute for Memory Impairments and Neurological Disorders. University of California. Irvine) ; Potter, H. (Department of Neurology. University of Colorado School of Medicine) ; Qu, L. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Quiceno, M. (Department of Medical Education. TCU/UNTHSC School of Medicine) ; Quinn, J.F. (Department of Neurology. Portland Veterans Affairs Medical Center) ; Raj, A. (USF Health Byrd Alzheimer's Institute. University of South Florida) ; Raskind, M. (Department of Psychiatry and Behavioral Sciences. University of Washington School of Medicine) ; Reiman, E.M. (Department of Psychiatry. University of Arizona) ; Reisberg, B. (Alzheimer's Disease Center. New York University) ; Reisch, J.S. (Department of Population and Data Sciences. University of Texas Southwestern Medical Center) ; Ringman, J.M. (Department of Neurology. University of Southern California) ; Roberson, E.D. (Department of Neurology. University of Alabama at Birmingham) ; Rodriguear, M. (Alzheimer's Disease and Memory Disorders Center. Baylor College of Medicine) ; Rogaeva, E. (Tanz Centre for Research in Neurodegenerative Disease. University of Toronto) ; Rosen, H.J. (Department of Neurology. University of California San Francisco) ; Rosenberg, R.N. (Department of Neurology. University of Texas Southwestern Medical Center) ; Royall, D.R. (Department of Family and Community Medicine. University of Texas Health Science Center San Antonio) ; Sager, M.A. (Department of Medicine. University of Wisconsin) ; Sano, M. (Department of Psychiatry. Icahn School of Medicine at Mount Sinai) ; Saykin, A.J. (Department of Radiology and Imaging Sciences. Indiana University) ; Schneider, J.A. (Department of Pathology (Neuropathology). Rush University Medical Center) ; Schneider, L.S. (Department of Psychiatry. University of Southern California) ; Seeley, W.W. (Department of Neurology. University of California San Francisco) ; Slifer, S.H. (The John P. Hussman Institute for Human Genomics. University of Miami) ; Small, S. (Gertrude H. Sergievsky Center. Columbia University) ; Smith, A.G. (USF Health Byrd Alzheimer's Institute. University of South Florida) ; Smith, J.P. (Department of Population and Data Sciences. University of Texas Southwestern Medical Center) ; Song, Y.E. (Department of Population and Quantitative Health Sciences. Case Western Reserve University) ; Sonnen, J.A. (Department of Laboratory Medicine and Pathology. University of Washington) ; Spina, S. (Department of Pathology and Laboratory Medicine. Indiana University) ; St George Hyslop, Peter (University of Toronto) ; Stern, R.A. (Institute of Biomedicine. University of Eastern Finland) ; Stevens, A.B. (College of Medicine. Texas A&M University Health Science Center) ; Strittmatter, S.M. (Program in Cellular Neuroscience. Neurodegeneration and Repair. Yale University School of Medicine) ; Sultzer, D. (Department of Psychiatry and Human Behavior. University of California. Irvine) ; Swerdlow, R.H. (University of Kansas Alzheimer's Disease Center. University of Kansas Medical Center) ; Tanzi, Rudolph E (Department of Neurology. Massachusetts General Hospital/Harvard Medical School) ; Tilson, J.L. (Renaissance Computing Institute. University of North Carolina at Chapel Hill) ; Trojanowski, J.Q. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; Troncoso, J.C. (Department of Pathology. Johns Hopkins University) ; Tsuang, D.W. (Department of Psychiatry and Behavioral Sciences. University of Washington School of Medicine) ; Valladares, Otto (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; Van Deerlin, V.M. (Department of Biostatistics. Epidemiology. and Informatics. Penn Neurodegeneration Genomics Center. University of Pennsylvania Perelman School of Medicine) ; van Eldik, L.J. (Sanders-Brown Center on Aging. Department of Biostatistics. University of Kentucky) ; Vassar, R. (Cognitive Neurology and Alzheimer's Disease Center. Northwestern University Feinberg School of Medicine) ; Vinters, H.V. (Department of Pathology and Laboratory Medicine. University of California. Los Angeles) ; Vonsattel, J.P. (Taub Institute on Alzheimer's Disease and the Aging Brain. Department of Neurology. Columbia University) ; Weintraub, S. (Department of Psychiatry and Behavioral Sciences. Northwestern University Feinberg School of Medicine) ; Welsh-Bohmer, K.A. (Department of Psychiatry and Behavioral Sciences. Duke University) ; Whitehead, P.L. (The John P. Hussman Institute for Human Genomics. University of Miami) ; Wijsman, E.M. (Department of Biostatistics. University of Washington) ; Wilhelmsen, K.C. (Department of Genetics. University of North Carolina at Chapel Hill) ; Williams, B. (Section of Gerontology and Geriatric Medicine Research. Wake Forest School of Medicine) ; Williamson, J. (Taub Institute on Alzheimer's Disease and the Aging Brain. Department of Neurology. Columbia University) ; Wilms, H. (Departments of Neurology. Pharmacology and Neuroscience. Texas Tech University Health Science Center) ; Wingo, T.S. (Department of Neurology. Emory University) ; Wisniewski, T. (Center for Cognitive Neurology and Departments of Neurology and Pathology. New York University Grossman School of Medicine) ; Woltjer, R.L. (Department of Pathology. Oregon Health and Science University) ; Woon, M. (Department of Psychiatry. University of Texas at Austin/Dell Medical School) ; Wright, C.B. (Evelyn F. McKnight Brain Institute. Department of Neurology. Miller School of Medicine. University of Miami) ; Wu, C.K. (Departments of Neurology. Pharmacology and Neuroscience. Texas Tech University Health Science Center) ; Younkin, S.G. (Department of Neurology. Mayo Clinic) ; Yu, C.E. (Department of Medicine. University of Washington) ; Yu, L. (Rush Alzheimer's Disease Center. Rush University Medical Center) ; Zhang, Y. (Center for Applied Genomics. Children's Hospital of Philadelphia) ; Zhao, Y. (Laboratory of Neuropsychiatry. Department of Clinical and Behavioral Neurology. IRCCS Santa Lucia Foundation) ; Zhu, X. (Department of Pathology. Case Western Reserve University) ; Adams, Hieab (Université de Lille. INSERM. CHU Lille. Institut Pasteur Lille. U1167-RID-AGE. Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Akinyemi, R.O. (Centre for Genomic and Precision Medicine. College of Medicine. UI) ; Ali, M. (Washington University at St. Louis) ; Aparicio, H.J. (Department of Neurology. Boston University School of Medicine) ; Bahadori, M. (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Becker, James T. (University of Pittsburgh) ; Breteler, M. (Population Health Sciences. German Center for Neurodegenerative Diseases (DZNE)) ; Chasman, D. (Brigham and Women's Hospital. Harvard University) ; Chauhan, G. (INSERM U1219. University of Bordeaux) ; Comic, H. (Department of Epidemiology. Erasmus MC) ; Cox, S. (University of Edinburgh) ; Cupples, A.L. (Department of Biostatistics. Boston University School of Public Health) ; Davies, G. (Centre for Cognitive Ageing and Cognitive Epidemiology. University of Edinburgh) ; DeCarli, C.S. (Department of Neurology and Center for Neuroscience. University of California. Davis) ; Duperron, M.G. (Bordeaux Population Health Research Center. Team VIN-TAGE. UMR 1219. University of Bordeaux. INSERM) ; Dupuis, J. (Department of Biostatistics. Boston University School of Public Health) ; Evans, T. (Department of Epidemiology. Erasmus MC) ; Fan, F. (University of Pittsburgh) ; Fitzpatrick, A. (Department of Family Medicine. University of Washington) ; Fohner, A.E. (Cardiovascular Health Research Unit. Department of Medicine. University of Washington) ; Ganguli, M. (University of Pittsburgh) ; Geerlings, M. (University Medical Center Utrecht) ; Glatt, S.J. (Psychiatric Genetic Epidemiology & Neurobiology Laboratory (PsychGENe Lab). Department of Psychiatry and Behavioral Sciences. SUNY Upstate Medical University) ; Gonzalez, H.M. (University of California. San Diego) ; Goss, M. (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Grabe, H. (Department of Psychiatry and Psychotherapy. University Medicine Greifswald) ; Habes, M. (Department of Radiology. University of Texas Health Science Center at San Antonio) ; Heckbert, S.R. (School of Public Health. University of Texas Health Science Center at Houston) ; Hofer, E. (Clinical Division of Neurogeriatrics. Department of Neurology. Medical University of Graz) ; Hong, E. (University of Maryland) ; Hughes, T. (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Kautz, T.F. (Department of General Medicine. University of Texas Health Science Center) ; Knol, M. (Department of Epidemiology. Erasmus MC) ; Kremen, W. (Department of Epidemiology. Erasmus MC) ; Lacaze, P. (Monash University Clayton Campus) ; Lahti, J. (University of Helsinki) ; Grand, Q.L. (Bordeaux Population Health Research Center. Team VIN-TAGE. UMR 1219. University of Bordeaux. INSERM) ; Litkowski, E. (University of Colorado Anschutz Medical Center) ; Li, S. (Department of Biostatistics. Boston University School of Public Health) ; Liu, D. (Population Health Sciences. German Center for Neurodegenerative Diseases (DZNE)) ; Liu, X. (Department of Biostatistics. Boston University School of Public Health) ; Loitfelder, M. (Medical University of Graz) ; Manning, A. (Massachusetts General Hospital. Harvard University) ; Maillard, P. (Imaging of Dementia and Aging (IDeA) Laboratory. Department of Neurology. University of California. Davis) ; Marioni, R. (University of Staffmail) ; Mazoyer, B. (University of Bordeaux. IMN) ; van Lent, D.M. (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Mei, H. (University of Mississippi Medical Center) ; Mishra, Aniket (Université de Bordeaux) ; Nyquist, P. (Johns Hopkins University School of Medicine) ; O'Connell, J. (University of Maryland) ; Patel, Y. (University of Toronto) ; Paus, T. (University of Montreal. Centre Hospitalier Universitaire Saint-Justine) ; Pausova, Z. (Hospital for Sick Children. University of Toronto) ; Raikkonen-Talvitie, K. (University of Helsinki) ; Riaz, M. (Monash University Clayton Campus) ; Rich, S. (Monash University Clayton Campus) ; Harbor-UCLA Medical Center. Los Angeles Biomedical Research Institute and Pediatrics ; Romero, J. (Boston Medical Center) ; Roshchupkin, G. (Department of Epidemiology. Erasmus MC) ; Saba, Y. (Gottfried Schatz Research Center. Department of Molecular Biology and Biochemistry. Medical University of Graz) ; Sargurupremraj, M. (Gottfried Schatz Research Center. Department of Molecular Biology and Biochemistry. Medical University of Graz) ; Schmidt, H. (Gottfried Schatz Research Center. Department of Molecular Biology and Biochemistry. Medical University of Graz) ; Schmidt, R. (Clinical Division of Neurogeriatrics. Department of Neurology. Medical University of Graz) ; Shulman, J.M. (Departments of Neurology. Molecular & Human Genetics. and Neuroscience and Program in Developmental Biology. Baylor College of Medicine) ; Smith, J. (Department of Epidemiology. School of Public Health. University of Michigan) ; Sekhar, H. (Bordeaux Population Health Research Center. Team VIN-TAGE. UMR 1219. University of Bordeaux. INSERM) ; Rajula, R. (Bordeaux Population Health Research Center. Team VIN-TAGE. UMR 1219. University of Bordeaux. INSERM) ; Shin, J. (Hospital for Sick Children. University of Toronto) ; Simino, J. (University of Mississippi Medical Center) ; Sliz, E. (University of Mississippi Medical Center) ; Teumer, A. (Institute for Community Medicine. University Medicine Greifswald) ; Thomas, A. (University of North Carolina) ; Tin, A. (University of Mississippi Medical Center) ; Tucker-Drob, E. (University of Texas) ; Vojinovic, D. (Department of Epidemiology. Erasmus MC) ; Wang, Y. (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Weinstein, G. (Clinical Division of Neurogeriatrics. Department of Neurology. Medical University of Graz) ; Williams, D. (Karolinska Institutet (Estocolm, Suècia)) ; Wittfeld, K. (German Center for Neurodegenerative Diseases (DZNE). Site Rostock/Greifswald) ; Yanek, L. (GeneSTAR Research Program. Department of Neurology. Johns Hopkins University School of Medicine) ; Yang, Y. (Institute of Molecular Medicine. University of Texas Health Science Center at Houston McGovern Medical School) ; Farrer, L.A. (Department of Neurology. Boston University School of Medicine) ; Psaty, B.M. (Department of Health Service. University of Washington) ; Ghanbari, M. (Department of Epidemiology. Erasmus MC) ; Raj, T. (Nash Family Department of Neuroscience & Friedman Brain Institute. Icahn School of Medicine at Mount Sinai) ; Sachdev, Perminder S. (University of New South Wales) ; Mather, Karen A (Centre for Healthy Brain Ageing. School of Psychiatry. Faculty of Medicine. University of New South Wales) ; Jessen, F. (German Center for Neurodegenerative Diseases (DZNE Bonn)) ; Ikram, M. Arfan (Department of Epidemiology. Erasmus MC) ; de Mendonça, A. (Faculty of Medicine. University of Lisbon) ; Hort, J. (Memory Clinic. Department of Neurology. Charles University. 2nd Faculty of Medicine and Motol University Hospital) ; Tsolaki, M. (Alzheimer Hellas) ; Pericak-Vance, Margaret A (AI Virtanen Institute for Molecular Sciences. University of Eastern Finland) ; Amouyel, Philippe (Université de Lille. INSERM. CHU Lille. Institut Pasteur Lille. U1167-RID-AGE. Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Williams, J. (UKDRI@ Cardiff. School of Medicine. Cardiff University) ; Frikke-Schmidt, R. (Department of Clinical Biochemistry. Rigshospitalet) ; Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Deleuze, J.F. (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Rossi, G. (Fondazione IRCCS. Istituto Neurologico Carlo Besta) ; Seshadri, S. (Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases. University of Texas Health Sciences Center) ; Andreassen, Ole A. (NORMENT Centre. University of Oslo) ; Ingelsson, Martin (Department of Public Health and Carins Sciences/Geriatrics. Uppsala University) ; Hiltunen, M. (Brain Institute. Federal University of Rio Grande do Norte) ; Sleegers, Kristel (Department of Biomedical Sciences. University of Antwerp) ; Schellenberg, G.D. (Department of Pathology and Laboratory Medicine. University of Pennsylvania Perelman School of Medicine) ; van Duijn, C.M. (Nuffield Department of Population Health. Oxford University) ; Sims, Rebecca (MRC Centre for Neuropsychiatric Genetics and Genomics. Division of Psychological Medicine and Clinical Neuroscience. School of Medicine. Cardiff University) ; van der Flier, Wiesje M (Alzheimer Center Amsterdam. Department of Neurology. Amsterdam Neuroscience. Vrije Universiteit Amsterdam. Amsterdam UMC) ; Ruiz, A. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Ramirez, A. (Universität zu Köln (Colònia, Alemaya). Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD)) ; Lambert, Jean-Charles (Université de Lille. INSERM. CHU Lille. Institut Pasteur Lille. U1167-RID-AGE. Facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Universitat Autònoma de Barcelona
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. [...]
2022 - 10.1038/s41588-022-01024-z
Nature genetics, Vol. 54 Núm. 4 (April 2022) , p. 412-436  
4.
23 p, 7.9 MB Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease / Holstege, Henne (Delft Bioinformatics Lab, Delft University of Technology) ; Hulsman, Marc (Delft Bioinformatics Lab, Delft University of Technology) ; Charbonnier, Camille (Université Rouen Normandie, INSERM U1245 and CHU Rouen, Department of Genetics and CNRMAJ) ; Grenier-Boley, Benjamin (Université Lille, INSERM, Centre Hospitalier Universitaire Lille, Institut Pasteur de Lille, U1167-RID-AGE facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Quenez, Olivier (Université Rouen Normandie, INSERM U1245 and CHU Rouen, Department of Genetics and CNRMAJ) ; Grozeva, Detelina (Cardiff University. Medical Research Council Centre for Neuropsychiatric Genetics and Genomics,, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine) ; van Rooij, Jeroen G. J. (Erasmus Medical Centre. Department of Internal Medicine) ; Sims, Rebecca (Cardiff University. Medical Research Council Centre for Neuropsychiatric Genetics and Genomics,, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine) ; Ahmad, Shahzad (Leiden Academic Centre for Drug Research) ; Amin, Najaf (Nuffield Department of Population Health Oxford University) ; Norsworthy, Penny J. (Medical Research Council Prion Unit at University College London, University College London Institute of Prion Diseases) ; Dols Icardo, Oriol (Institut d'Investigació Biomèdica Sant Pau) ; Hummerich, Holger (Medical Research Council Prion Unit at University College London, University College London Institute of Prion Diseases) ; Kawalia, Amit (Faculty of Medicine and University Hospital Cologne, University of Cologne. Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy) ; Amouyel, Philippe (Université Lille, INSERM, Centre Hospitalier Universitaire Lille, Institut Pasteur de Lille, U1167-RID-AGE facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Beecham, Gary W. (The John P. Hussman Institute for Human Genomics, University of Miami) ; Berr, Claudine (Université Montpellier, INSERM, Institute for Neurosciences of Montpellier) ; Bis, Joshua C. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Boland, Anne (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Bossù, Paola (Istituto di Ricovero e Cura a Carattere Scientifico Santa Lucia Foundation. Experimental Neuro-psychobiology Laboratory, Department of Clinical and Behavioral Neurology) ; Bouwman, Femke (Amsterdam Neuroscience, Neurodegeneration) ; Bras, Jose (Michigan State University College of Human Medicine. Division of Psychiatry and Behavioral Medicine) ; Campion, Dominique (Université Rouen Normandie, INSERM U1245 and CHU Rouen, Department of Genetics and CNRMAJ) ; Cochran, J. Nicholas (HudsonAlpha Institute for Biotechnology) ; Daniele, Antonio (Catholic University of Sacred Heart, Fondazione Policlinico Universitario A. Gemelli Istituto di Ricovero e Cura a Carattere Scientifico. Department of Neuroscience) ; Dartigues, Jean-François (Université Bordeaux, INSERM, Bordeaux Population Health Research Center) ; Debette, Stéphanie (Bordeaux University Hospital. Department of Neurology) ; Deleuze, Jean-François (Université Paris-Saclay. Centre National de Recherche en Génomique Humaine) ; Denning, Nicola (Cardiff University. UKDRI Cardiff, School of Medicine) ; DeStefano, Anita L. (Boston University School of Medicine. Department of Neurology) ; Farrer, Lindsay A. (Boston University. Department of Medicine (Biomedical Genetics)) ; Fernández, Maria Victoria (Washington University School of Medicine. Hope Center for Neurological Disorders) ; Fox, Nick C. (University College London Queen Square Institute of Neurology. Dementia Research Centre) ; Galimberti, Daniela (University of Milan) ; Genin, Emmanuelle (Université Brest, INSERM, Etablissement Français du Sang, Centre Hospitalier Universitaire Brest, Unité Mixte de Recherche 1078, GGB, Brest, France) ; Gille, Johan J. P. (VU University, AmsterdamUMC (location VUmc). Genome Diagnostics, Department of Human Genetics) ; Le Guen, Yann (Stanford University. Department of Neurology and Neurological Sciences) ; Guerreiro, Rita (Michigan State University College of Human Medicine. Division of Psychiatry and Behavioral Medicine) ; Haines, Jonathan L. (Case Western Reserve University. Department of Epidemiology and Biostatistics) ; Holmes, Clive (University of Southampton. Clinical and Experimental Science, Faculty of Medicine) ; Ikram, M. Arfan (Erasmus Medical Centre. Department of Epidemiology) ; Ikram, M. Kamran (Erasmus Medical Centre. Department of Epidemiology) ; Jansen, Iris E. (Vrije University. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience) ; Kraaij, Robert (Erasmus Medical Centre. Department of Internal Medicine) ; Lathrop, Marc (McGill University and Genome Quebec Innovation Centre) ; Lemstra, Afina W. (Amsterdam Neuroscience, Neurodegeneration) ; Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ; Luckcuck, Lauren (Cardiff University. Medical Research Council Centre for Neuropsychiatric Genetics and Genomics) ; Mannens, Marcel M. A. M. (University of Amsterdam, Amsterdam Reproduction and Development Research Institute. Department of Human Genetics, Amsterdam UMC) ; Marshall, Rachel (Cardiff University. Medical Research Council Centre for Neuropsychiatric Genetics and Genomics,, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine) ; Martin, Eden R. (University of Miami. Dr. John T. Macdonald Foundation Department of Human Genetics) ; Masullo, Carlo (Institute of Neurology, Catholic University of the Sacred Heart) ; Mayeux, Richard (Columbia University. Gertrude H. Sergievsky Center) ; Mecocci, Patrizia (University of Perugia. Institute of Gerontology and Geriatrics, Department of Medicine and Surgery) ; Meggy, Alun (Cardiff University. UKDRI Cardiff, School of Medicine) ; Mol, Merel O. (Erasmus Medical Centre. Department of Neurology) ; Morgan, Kevin (University of Nottingham. Human Genetics, School of Life Sciences) ; Myers, Richard M. (HudsonAlpha Institute for Biotechnology) ; Nacmias, Benedetta (IRCCS Fondazione Don Carlo Gnocchi) ; Naj, Adam C. (University of Pennsylvania Perelman School of Medicine. Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine) ; Napolioni, Valerio (Genomic and Molecular Epidemiology Laboratory, School of Biosciences and Veterinary Medicine, University of Camerino) ; Pasquier, Florence (Université Lille, INSERM, Centre Hospitalier Universitaire Lille, UMR1172, Resources and Research Memory Center (MRRC) of Distalz, Licend) ; Pastor, Pau (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ; Pericak-Vance, Margaret A. (University of Miami. Dr. John T. Macdonald Foundation Department of Human Genetics) ; Raybould, Rachel (Cardiff University. UKDRI Cardiff, School of Medicine) ; Redon, Richard (Université de Nantes, Centre Hospitalier Universitaire Nantes, Centre National de la Recherche Scientifique, INSERM, l'institut du Thorax) ; Reinders, Marcel J. T. (Delft Bioinformatics Lab, Delft University of Technology) ; Richard, Anne-Claire (Université Rouen Normandie, INSERM U1245 and CHU Rouen, Department of Genetics and CNRMAJ) ; Riedel-Heller, Steffi G. (Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig) ; Rivadeneira, Fernando (Erasmus Medical Centre. Department of Internal Medicine) ; Rousseau, Stéphane (Université Rouen Normandie, INSERM U1245 and CHU Rouen, Department of Genetics and CNRMAJ) ; Ryan, Natalie S. (University College London Queen Square Institute of Neurology. Dementia Research Centre) ; Saad, Salha (Cardiff University. Medical Research Council Centre for Neuropsychiatric Genetics and Genomics,, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine) ; Sánchez-Juan, Pascual (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ; Schellenberg, Gerard D. (University of Pennsylvania Perelman School of Medicine. Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine) ; Scheltens, Philip (Amsterdam Neuroscience, Neurodegeneration) ; Schott, Jonathan M. (University College London Queen Square Institute of Neurology. Dementia Research Centre) ; Seripa, Davide (Laboratory for Advanced Hematological Diagnostics, Department of Hematology and Stem Cell Transplant, Lecce, Italy) ; Seshadri, Sudha (Department of Psychiatry and Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX USA) ; Sie, Daoud (VU University, AmsterdamUMC (location VUmc). Genome Diagnostics, Department of Human Genetics) ; Sistermans, Erik A. (VU University, AmsterdamUMC (location VUmc). Genome Diagnostics, Department of Human Genetics) ; Sorbi, Sandro (IRCCS Fondazione Don Carlo Gnocchi) ; van Spaendonk, Resie (VU University, AmsterdamUMC (location VUmc). Genome Diagnostics, Department of Human Genetics) ; Spalletta, Gianfranco (Istituto di Ricovero e Cura a Carattere Scientifico Santa Lucia Foundation. Laboratory of Neuropsychiatry, Department of Clinical and Behavioral Neurology) ; Tesi, Niccolo (Delft Bioinformatics Lab, Delft University of Technology) ; Tijms, Betty (Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc. Alzheimer Center Amsterdam, Neurology) ; Uitterlinden, André G. (Erasmus Medical Centre. Department of Internal Medicine) ; van der Lee, Sven J. (Delft Bioinformatics Lab, Delft University of Technology) ; Visser, Pieter Jelle (Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc. Alzheimer Center Amsterdam, Neurology) ; Wagner, Michael (German Center for Neurodegenerative Diseases) ; Wallon, David (Université Rouen Normandie, INSERM U1245 and CHU Rouen, Department of Neurology and CNRMAJ) ; Wang, Li-San (University of Pennsylvania Perelman School of Medicine. Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine) ; Zarea, Aline (Université Rouen Normandie, INSERM U1245 and CHU Rouen, Department of Neurology and CNRMAJ) ; Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; van Swieten, John C. (Erasmus Medical Centre. Department of Neurology) ; Greicius, Michael D. (Stanford University. Department of Neurology and Neurological Sciences) ; Yokoyama, Jennifer S. (University of California. Memory and Aging Center, Department of Neurology) ; Cruchaga, Carlos (Washington University School of Medicine. Hope Center for Neurological Disorders) ; Hardy, John (University College London Institute of Neurology. Reta Lila Weston Research Laboratories, Department of Molecular Neuroscience) ; Ramirez, Alfredo (University of Cologne. Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases) ; Mead, Simon (University College London. Institute of Prion Diseases) ; van der Flier, Wiesje M. (Amsterdam Neuroscience, Neurodegeneration) ; van Duijn, Cornelia M. (Nuffield Department of Population Health Oxford University) ; Williams, Julie (Cardiff University. Medical Research Council Centre for Neuropsychiatric Genetics and Genomics,, Division of Psychological Medicine and Clinical Neuroscience, School of Medicine) ; Nicolas, Gaël (Université Rouen Normandie, INSERM U1245 and CHU Rouen, Department of Genetics and CNRMAJ) ; Bellenguez, Céline (Université Lille, INSERM, Centre Hospitalier Universitaire Lille, Institut Pasteur de Lille, U1167-RID-AGE facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Lambert, Jean-Charles (Université Lille, INSERM, Centre Hospitalier Universitaire Lille, Institut Pasteur de Lille, U1167-RID-AGE facteurs de risque et déterminants moléculaires des maladies liées au vieillissement) ; Universitat Autònoma de Barcelona
Alzheimer's disease (AD), the leading cause of dementia, has an estimated heritability of approximately 70% . The genetic component of AD has been mainly assessed using genome-wide association studies, which do not capture the risk contributed by rare variants . [...]
2022 - 10.1038/s41588-022-01208-7
Nature genetics, Vol. 54 (november 2022) , p. 1786-1794  
5.
13 p, 1.3 MB Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease / Escott-Price, Valentina (Clinical Cardiff University) ; Bellenguez, Céline (Institut Pasteur de Lille, Lille, France) ; Wang, Li-San (Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America) ; Choi, Seung-Hoan (Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America) ; Harold, Denise (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Jones, Lesley (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Holmans, Peter (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Gerrish, Amy (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Vedernikov, Alexey (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Richards, Alexander (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; DeStefano, Anita L. (Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America) ; Lambert, Jean-Charles (Institut Pasteur de Lille, Lille, France) ; Ibrahim-Verbaas, Carla A. (Department of Epidemiology and Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands) ; Naj, Adam C. (University of Pennsylvania Perelman School of Medicine. Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine) ; Sims, Rebecca (Cardiff University. Institute of Psychological Medicine and Clinical Neurosciences) ; Jun, Gyungah (Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, United States of America) ; Bis, Joshua C. (Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America) ; Beecham, Gary W. (Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America) ; Grenier-Boley, Benjamin (Institut Pasteur de Lille, Lille, France) ; Russo, Giancarlo (Functional Genomics Center Zurich, ETH/University of Zurich, Zurich, Switzerland) ; Thornton-Wells, Tricia A. (Vanderbilt University (Nashville, Estats Units d'Amèrica)) ; Denning, Nicola (Cardiff University) ; Smith, Albert V. (Icelandic Heart Association, Kopavogur, Iceland) ; Chouraki, Vincent (Boston University School of Medicine) ; Thomas, Charlene (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Ikram, M. Arfan (Netherlands Consortium for Healthy Aging, Leiden, The Netherlands) ; Zelenika, Diana (Centre National de Genotypage, Institut Genomique, Commissariat à l'énergie Atomique, Evry, France) ; Vardarajan, Badri N. (Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America) ; Kamatani, Yoichiro (Fondation Jean Dausset- CEPH, Paris, France) ; Lin, Chiao-Feng (Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America) ; Schmidt, Helena (Institute for Molecular Biology and Biochemistry, Medical University of Graz, Graz, Austria) ; Kunkle, Brian (The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America) ; Dunstan, Melanie L. (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Vronskaya, Maria (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Johnson, Andrew D. (NHLBI Cardiovascular Epidemiology and Human Genomics Branch, The Framingham Heart Study, Framingham, Massachusetts, United States of America) ; Ruiz, Agustin (Fundació ACE) ; Bihoreau, Marie-Thérèse (Centre National de Genotypage, Institut Genomique, Commissariat à l'énergie Atomique, Evry, France) ; Reitz, Christiane (Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America) ; Pasquier, Florence (CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Lille, France) ; Hollingworth, Paul (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Hanon, Olivier (University Paris Descartes, Sorbonne Paris V, Broca Hospital, Geriatrics department, Paris, France) ; Fitzpatrick, Annette L. (Departments of Epidemiology and Global Health, University of Washington, Seattle, Washington, United States of America) ; Buxbaum, Joseph D (Icahn School of Medicine at Mount Sinai) ; Campion, Dominique (CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France) ; Crane, Paul K. (Department of Medicine, University of Washington, Seattle, Washington, United States of America) ; Baldwin, Clinton (Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts, United States of America) ; Becker, Tim (German Center for Neurodegenerative Diseases (DZNE), Bonn, and Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn, Germany) ; Gudnason, Vilmundur (Icelandic Heart Association, Kopavogur, Iceland) ; Cruchaga, Carlos (Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, United States of America) ; Craig, David (Queen's University Belfast. Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences) ; Amin, Najaf (Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands) ; Berr, Claudine (Université Montpellier, INSERM, Institute for Neurosciences of Montpellier) ; Lopez, Oscar L. (Departments of Neurology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America) ; De Jager, Philip L. (Program in Medical and Population Genetics, Broad Institute, Boston, Massachusetts, United States of America) ; Deramecourt, Vincent (CNR-MAJ, Centre Hospitalier Régional Universitaire de Lille, Lille, France) ; Johnston, Janet A. (Queen's University Belfast. Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences) ; Evans, Denis (Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America) ; Lovestone, Simon (King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom) ; Letenneur, Luc (Inserm U897, Victor Segalen University, F-33076, Bordeaux, France) ; Hernández, Isabel (Fundació ACE) ; Rubinsztein, David C. (Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom) ; Eiriksdottir, Gudny (Icelandic Heart Association, Kopavogur, Iceland) ; Sleegers, Kristel (Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium) ; Goate, Alison M. (Department of Psychiatry and Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, Missouri, United States of America) ; Fiévet, Nathalie (Institut Pasteur de Lille, Lille, France) ; Huentelman, Matthew J. (Neurogenomics Division, Translational Genomics Research Institute, Phoenix, Arizona, United States of America) ; Gill, Michael (Discipline of Psychiatry, Trinity College, Dublin, Ireland) ; Brown, Kristelle (Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, United Kingdom) ; Kamboh, M. Ilyas (Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America) ; Keller, Lina (Aging Reasearch Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden) ; Barberger-Gateau, Pascale (King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom) ; McGuinness, Bernadette (Queen's University Belfast. Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences) ; Larson, Eric B. (Group Health Research Institute, Group Health, Seattle, Washington, United States of America) ; Myers, Amanda J. (Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, Florida, United States of America) ; Dufouil, Carole (Inserm U897, Victor Segalen University, F-33076, Bordeaux, France) ; Todd, Stephen (Queen's University Belfast. Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences) ; Wallon, David (CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France) ; Love, Seth (University of Bristol Institute of Clinical Neurosciences, School of Clinical Sciences, Frenchay Hospital, Bristol, United Kingdom) ; Rogaeva, Ekaterina (Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada) ; Gallacher, John (Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, United Kingdom) ; St George Hyslop, Peter (Cambridge Institute for Medical Research and Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom) ; Clarimón, Jordi (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Lleo, Alberto (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Bayer, Anthony (Institute of Primary Care and Public Health, Cardiff University, Neuadd Meirionnydd, University Hospital of Wales, Heath Park, Cardiff, United Kingdom) ; Tsuang, Debby W. (Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, Washington, United States of America) ; Yu, Lei (Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, United States of America) ; Tsolaki, Magda (3rd Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece) ; Bossù, Paola (Clinical and Behavioral Neurology, Fondazione Santa Lucia, Roma, Italy) ; Spalletta, Gianfranco (Clinical and Behavioral Neurology, Fondazione Santa Lucia, Roma, Italy) ; Proitsi, Petra (King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom) ; Collinge, John (MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom) ; Sorbi, Sandro (Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy) ; Garcia, Florentino Sanchez (Hospital Universitario de Gran Canaria Dr. Negrín) ; Fox, Nick C. (University College London Queen Square Institute of Neurology. Dementia Research Centre) ; Hardy, John (Department of Molecular Neuroscience and Reta Lilla Weston Laboratories, Institute of Neurology, London, United Kingdom) ; Naranjo, Maria Candida Deniz (Hospital Universitario de Gran Canaria Dr. Negrín) ; Bosco, Paolo (IRCCS Associazione Oasi Maria SS, Troina, Italy) ; Clarke, Robert (Oxford Healthy Aging Project (OHAP), Clinical Trial Service Unit, University of Oxford, Oxford, United Kingdom) ; Brayne, Carol (Cognitive Function and Ageing Study (CFAS), Institute of Public Health, University of Cambridge, Cambridge, United Kingdom) ; Galimberti, Daniela (University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy) ; Scarpini, Elio (University of Milan, Fondazione Cà Granda, IRCCS Ospedale Policlinico, Milan, Italy) ; Bonuccelli, Ubaldo (Neurological Clinic, University of Pisa, Pisa, Italy) ; Mancuso, Michelangelo (Neurological Clinic, University of Pisa, Pisa, Italy) ; Siciliano, Gabriele (Neurological Clinic, University of Pisa, Pisa, Italy) ; Moebus, Susanne (Urban Epidemiology, Institute for Medical Informatics, Biometry and Epidemiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany) ; Mecocci, Patrizia (University of Perugia (Itàlia)) ; Zompo, Maria Del (Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy) ; Maier, Wolfgang (Department of Psychiatry and Psychotherapy, University of Bonn, Germany and German Center for Neurodegenerative Diseases (DZNE, Bonn), Bonn, Germany) ; Hampel, Harald (Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany) ; Pilotto, Alberto (Gerontology and Geriatrics Research Laboratory, I.R.C.C.S. Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy) ; Frank-García, Ana (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ; Panza, F. (University of Bari Aldo Moro) ; Solfrizzi, Vincenzo (Department of Geriatrics,Center for Aging Brain,University of Bari, Bari, Italy) ; Caffarra, Paolo (Center for Cognitive Disorders AUSL, Parma, Italy) ; Nacmias, Benedetta (Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy) ; Perry, William (Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America) ; Mayhaus, Manuel (Department Of Psychiatry, University Hospital, Saarland, Germany) ; Lannfelt, Lars (Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden) ; Hakonarson, Hakon (Children's Hospital of Philadelphia (Pennsilvània)) ; Pichler, Sabrina (Department Of Psychiatry, University Hospital, Saarland, Germany) ; Carrasquillo, Minerva M. (Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America) ; Ingelsson, Martin (Department of Public Health/Geriatrics, Uppsala University, Uppsala, Sweden) ; Beekly, Duane (National Alzheimer's Coordinating Center, University of Washington, Seattle, Washington, United States of America) ; Alvarez, Victoria (Genetica molecular-Huca-Oviedo, Oviedo, Spain) ; Zou, Fanggeng (Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America) ; Valladares, Otto (University of Pennsylvania Perelman School of Medicine) ; Younkin, Steven G. (Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America) ; Coto, Eliecer (Genetica molecular-Huca-Oviedo, Oviedo, Spain) ; Hamilton-Nelson, Kara L. (The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, United States of America) ; Gu, Wei (Department of Psychiatry, University Hospital, Saarland, Germany) ; Razquin, Cristina (Neurogenetics Laboratory, Division of Neurosciences, Center for Applied Medical Research, University of Navarra School of Medicine, Pamplona, Spain) ; Pastor, Pau (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Mateo, Ignacio (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; Owen, Michael J. (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Faber, Kelley M. (Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, United States of America) ; Jonsson, Palmi V. (Landspitali University Hospital (Reykjavík, Islàndia)) ; Combarros, Onofre (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ; O'Donovan, Michael C. (Cardiff University) ; Cantwell, Laura B. (Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America) ; Soininen, Hilkka (Kuopio University Hospital ( Finlàndia)) ; Blacker, Deborah (Massachusetts General Hospital (Boston)) ; Mead, Simon (University College London. Institute of Neurology) ; Mosley, Thomas H. (Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi, United States of America) ; Bennett, David A. (Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America) ; Harris, Tamara B. (Laboratory of Epidemiology, Demography, and Biometry, National Institute of Health, Bethesda, Maryland, United States of America) ; Fratiglioni, Laura (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Holmes, Clive (Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, United Kingdom) ; de Bruijn, Renee F. A. G. (Departments of Neurology and Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands) ; Passmore, Peter (Queen's University Belfast. Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences) ; Montine, Thomas J. (Department of Pathology, University of Washington, Seattle, Washington, United States of America) ; Bettens, Karolien (Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium) ; Rotter, Jerome I. (Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, United States of America) ; Brice, Alexis (AP-HP, Hôpital de la Pitié-Salpêtrière, Paris, France) ; Morgan, Kevin (Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, United Kingdom) ; Foroud, Tatiana M. (Department of Medical and Molecular Genetics, Indiana University, Indianapolis, Indiana, United States of America) ; Kukull, Walter A. (Department of Epidemiology, University of Washington, Seattle, Washington, United States of America) ; Hannequin, Didier (CNR-MAJ, Inserm U1079, Rouen University Hospital, 76031 France, Rouen, France) ; Powell, John F. (King's College London, Institute of Psychiatry, Department of Neuroscience, De Crespigny Park, Denmark Hill, London, United Kingom) ; Nalls, Michael A.. (Laboratory of Neurogenetics, Intramural Research Program, National Institute on Aging, Bethesda, Maryland, United States of America) ; Ritchie, Karen (Imperial College, London, United Kingdom) ; Lunetta, Kathryn L. (Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America) ; Kauwe, John S. K. (Department of Biology, Brigham Young University, Provo, Utah, United States of America) ; Boerwinkle, Eric (Human Genetics Center and Div. of Epidemiology, University of Texas Health Sciences Center at Houston, Houston, Texas, United States of America) ; Riemenschneider, Matthias (Department of Psychiatry, University Hospital, Saarland, Germany) ; Boada, Mercè (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hiltunen, Mikko (Kuopio University Hospital ( Finlàndia)) ; Martin, Eden R. (Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America) ; Schmidt, Reinhold (Department of Neurology, Medical University Graz, Graz, Austria) ; Rujescu, Dan (Department of Psychiatry, Ludwig-Maximilians University, Munich, Germany) ; Dartigues, Jean-François (Centre de Mémoire de Ressources et de Recherche de Bordeaux, CHU de Bordeaux, Bordeaux, France) ; Mayeux, Richard (Gertrude H. Sergievsky Center, Department of Neurology, Columbia University, New York, New York, United States of America) ; Tzourio, Christophe (Inserm U708, Victor Segalen University, Bordeaux, France) ; Hofman, Albert (Netherlands Consortium for Healthy Aging, Leiden, The Netherlands) ; Nöthen, Markus M. (University of Bonn. Life and Brain Center) ; Graff, Caroline (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ; Psaty, Bruce M. (Group Health Research Institute, Group Health Cooperative, Seattle, Washington, United States of America) ; Haines, Jonathan L. (Department of Epidemiology & Biostatistics, Case Western Reserve University, Cleveland, Ohio, United States of America) ; Lathrop, Mark (McGill University and Génome Québec Innovation Centre, Montreal, Canada) ; Pericak-Vance, Margaret A. (Dr. John T. Macdonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, United States of America) ; Launer, Lenore J. (Laboratory of Epidemiology, Demography, and Biometry, National Institute of Health, Bethesda, Maryland, United States of America) ; Van Broeckhoven, Christine (Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium) ; Farrer, Lindsay A. (Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, United States of America) ; van Duijn, Cornelia M. (Center for Medical Systems Biology, Leiden, The Netherlands) ; Ramirez, Alfredo (Department of Psychiatry and Psychotherapy and Institute of Human Genetics, University of Bonn, Bonn, Germany) ; Seshadri, Sudha (The Framingham Heart Study, Framingham, Massachusetts, United States of America) ; Schellenberg, Gerard D. (Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America) ; Amouyel, Philippe (Centre Hospitalier Régional Universitaire de Lille, Lille, France) ; Williams, Julie (Institute of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics & Genomics, Cardiff University, Cardiff, United Kingdom) ; Universitat Autònoma de Barcelona
Alzheimer's disease is a common debilitating dementia with known heritability, for which 20 late onset susceptibility loci have been identified, but more remain to be discovered. This study sought to identify new susceptibility genes, using an alternative gene-wide analytical approach which tests for patterns of association within genes, in the powerful genome-wide association dataset of the International Genomics of Alzheimer's Project Consortium, comprising over 7 m genotypes from 25,580 Alzheimer's cases and 48,466 controls. [...]
2014 - 10.1371/journal.pone.0094661
PloS one, Vol. 9 (june 2014)  
6.
17 p, 5.3 MB Associations of autozygosity with a broad range of human phenotypes / Clark, David W. (University of Edinburgh) ; Okada, Yukinori (Osaka University, Suita) ; Moore, Kristjan H. S. (deCODE genetics/Amgen Inc., Reykjavik, Iceland) ; Mason, Dan (Bradford Teaching Hospitals NHS Trust, Bradford, UK) ; Pirastu, Nicola (University of Edinburgh, Usher Institute) ; Gandin, Ilaria (University of Trieste) ; Mattsson, Hannele (University of Helsinki) ; Barnes, Catriona L. K. (University of Edinburgh) ; Lin, Kuang (University of Oxford) ; Zhao, Jing Hua (University of Cambridge) ; Deelen, Patrick (University Medical Centre Groningen, University of Groningen) ; Rohde, Rebecca (University of North Carolina. Department of Epidemiology) ; Schurmann, Claudia (Ichan School of Medicine at Mount Sinai) ; Guo, Xiuqing (The Institute for Translational Genomics and Population Sciences, Torrance, California, USA) ; Giulianini, Franco (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Zhang, Weihua (Ealing Hospital, Middlesex) ; Medina-Gomez, Carolina (Erasmus University Medical Center) ; Karlsson, Robert (Karolinska Institutet (Estocolm, Suècia)) ; Bao, Yanchun (University of Essex) ; Bartz, Traci M. (University of Washington) ; Baumbach, Clemens (Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg) ; Biino, Ginevra (National Research Council of Italy) ; Bixley, Matthew J. (University of Otago) ; Brumat, Marco (University of Trieste) ; Chai, Jin-Fang (National University of Singapore, Singapore) ; Corre, Tanguy (Swiss Institute of Bioinformatics) ; Cousminer, Diana L. (University of Pennsylvania) ; Dekker, Annelot M. (Utrecht University) ; Eccles, David (Instituto de Investigación Biomédica de Málaga) ; van Eijk, Kristel R. (Utrecht University) ; Fuchsberger, Christian (Affiliated Institute of the University of Lübeck, Bolzano, Italy) ; Gao, He (Imperial College London) ; Germain, Marine (ICAN Institute for Cardiometabolism and Nutrition) ; Gordon, Scott D. (QIMR Berghofer Institute of Medical Research) ; de Haan, Hugoline G. (Leiden University Medical Center) ; Harris, Sarah E. (University of Edinburgh) ; Hofer, Edith (Medical University of Graz) ; Huerta-Chagoya, Alicia (CONACyT, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, 03940 México) ; Igartua, Catherine (University of Chicago. Department of Human Genetics) ; Jansen, Iris E. (VU University Medical Center, Amsterdam Neuroscience. Alzheimer Center Department of Neurology) ; Jia, Yucheng (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502 USA) ; Kacprowski, Tim (TUM School of Life Sciences Weihenstephan, Technical University of Munich. Chair of Experimental Bioinformatics) ; Karlsson, Torgny (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Kleber, Marcus E. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Li, Shengchao Alfred (Leidos Biomedical Research, Inc., Frederick National Lab for Cancer Research. Cancer Genomics Research Laboratory) ; Li-Gao, Ruifang (Leiden University Medical Center. Department of Clinical Epidemiology) ; Mahajan, Anubha (University of Oxford. Wellcome Centre for Human Genetics) ; Matsuda, Koichi (Graduate school of Frontier Sciences, The University of Tokyo. Department of Computational Biology and Medical Sciences) ; Meidtner, Karina (German Center for Diabetes Research (DZD)) ; Meng, Weihua (Medical Research Institute, Ninewells Hospital and School of Medicine, University of Dundee) ; Montasser, May E. (University of Maryland, School of Medicine. Program for Personalized and Genomic Medicine, Department of Medicine) ; van der Most, Peter J. (University of Groningen, University Medical Center Groningen. Department of Epidemiology) ; Munz, Matthias (Humboldt-Universität zu Berlin) ; Nutile, Teresa (Institute of Genetics and Biophysics A. Buzzati-Traverso - CNR) ; Palviainen, Teemu (Finnish Institute for Molecular Medicine, University of Helsinki) ; Prasad, Gauri (Genomics and Molecular Medicine Unit, CSIR-Institute of Genomics and Integrative Biology) ; Prasad, Rashmi B. (Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, 20502 Sweden) ; Priyanka, Tallapragada Divya Sri (CSIR-Centre for Cellular and Molecular Biology. Genomic Research on Complex diseases (GRC Group)) ; Rizzi, Federica (University of Milano. Department of Health Sciences) ; Salvi, Erika (IRCCS Foundation Carlo Besta Neurological Institute. Neuroalgology Unit) ; Sapkota, Bishwa R. (University of Oklahoma Health Sciences Center. Department of Pediatrics, College of Medicine) ; Shriner, Daniel (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Skotte, Line (Statens Serum Institut. Department of Epidemiology Research) ; Smart, Melissa C. (Institute for Social and Economic Research, University of Essex) ; Smith, Albert Vernon (University of Iceland. Faculty of Medicine, School of Health Sciences) ; van der Spek, Ashley (Erasmus University Medical Center. Department of Epidemiology) ; Spracklen, Cassandra N. (University of North Carolina. Department of Genetics) ; Strawbridge, Rona J. (Karolinska Institutet. Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine) ; Tajuddin, Salman M. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Trompet, Stella (Leiden University Medical Center. Section of Gerontology and Geriatrics, Department of Internal Medicine) ; Turman, Constance (Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health) ; Verweij, Niek (University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands) ; Viberti, Clara (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; Wang, Lihua (Washington University School of Medicine. Division of Statistical Genomics, Department of Genetics) ; Warren, Helen R. (William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London. Department of Clinical Pharmacology) ; Wootton, Robyn E. (School of Psychological Science, University of Bristol) ; Yanek, Lisa R. (Johns Hopkins University School of Medicine. Department of Medicine, GeneSTAR Research Program) ; Yao, Jie (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, 90502 USA) ; Yousri, Noha A. (Alexandria University. Computer and Systems Engineering) ; Zhao, Wei (University of Michigan. Department of Epidemiology, School of Public Health) ; Adeyemo, Adebowale A. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Afaq, Saima (Imperial College London. Department of Epidemiology and Biostatistics) ; Aguilar-Salinas, Carlos Alberto (Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud. Unidad de Investigacion de Enfermades Metabolicas) ; Akiyama, Masato (Graduate School of Medical Sciences, Kyushu University, Fukuoka. Department of Ophthalmology) ; Albert, Matthew L. (Genentech Inc. Department of Cancer Immunology) ; Allison, Matthew A. (UC San Diego School of Medicine. Division of Preventive Medicine, Department of Family Medicine and Public Health) ; Alver, Maris (University of Tartu, University of Tartu. Estonian Genome Center) ; Aung, Tin (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Azizi, Fereidoun (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Endocrine Research Center) ; Bentley, Amy R. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Boeing, Heiner (German Institute of Human Nutrition Potsdam-Rehbruecke. Department of Epidemiology) ; Boerwinkle, Eric (UTHealth School of Public Health, University of Texas. Health Science Center at Houston) ; Borja, Judith B. (USC-Office of Population Studies Foundation, Inc., Department of Nutrition and Dietetics, Talamban, University of San Carlos) ; de Borst, Gert J. (University Medical Center Utrecht) ; Bottinger, Erwin P. (Hasso Plattner Institute, Universität Potsdam. Digital Health Center) ; Broer, Linda (Erasmus University Medical Center. Department of Internal Medicine) ; Campbell, Harry (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Chanock, Stephen (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Chee, Miao-Li (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Chen, Guanjie (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Chen, Yii Der Ida (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Chen, Zhengming (University of Oxford. Nuffield Department of Population Health) ; Chiu, Yen-Feng (Institute of Population Health Sciences, National Health Research Institutes) ; Cocca, Massimiliano (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; Collins, Francis S. (National Human Genome Research Institute, National Institutes of Health) ; Concas, Maria Pina (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; Corley, Janie (University of Edinburgh. Department of Psychology) ; Cugliari, Giovanni (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; van Dam, Rob M. (Harvard T.H. Chan School of Public Health. Department of Nutrition) ; Damulina, Anna (Medical University of Graz. Clinical Division of Neurogeriatrics, Department of Neurology) ; Daneshpour, Maryam S. (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Day, Felix R. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Delgado, Graciela E. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Dhana, Klodian (Rush University Medical Center. Department of Internal Medicine) ; Doney, Alexander S. F. (Molecular and Clinical Medicine, University of Dundee. MEMO Research) ; Dörr, Marcus (DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475 Germany) ; Doumatey, Ayo P. (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Dzimiri, Nduna (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ; Ebenesersdóttir, S. Sunna (University of Iceland. Department of Anthropology) ; Elliott, Joshua (Imperial College London. Department of Epidemiology and Biostatistics) ; Elliott, Paul (Health Data Research UK - London, London, England) ; Ewert, Ralf (University Medicine Greifswald. Department of Internal Medicine B) ; Felix, Janine F. (Erasmus University Medical Center. Department of Pediatrics) ; Fischer, Krista (University of Tartu, University of Tartu. Estonian Genome Center) ; Freedman, Barry I (Wake Forest School of Medicine. Section on Nephrology, Department of Internal Medicine) ; Girotto, Giorgia (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Goel, Anuj (University of Oxford. Division of Cardiovascular Medicine, Radcliffe Department of Medicine) ; Gögele, Martin (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Goodarzi, Mark O. (Cedars-Sinai Medical Center. Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine) ; Graff, Mariaelisa (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Granot-Hershkovitz, Einat (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Grodstein, Francine (Harvard T.H. Chan School of Public Health. Department of Epidemiology) ; Guarrera, Simonetta (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; Gudbjartsson, Daniel F. (School of Engineering and Natural Sciences, University of Iceland) ; Guity, Kamran (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Gunnarsson, Bjarni (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Guo, Yu (Chinese Academy of Medical Sciences) ; Hagenaars, Saskia P. (Institute of Psychiatry, Psychology & Neuroscience, King's College London. Social, Genetic and Developmental Psychiatry Centre) ; Haiman, Christopher A. (Keck School of Medicine, University of Southern California. Department of Preventive Medicine) ; Halevy, Avner (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Harris, Tamara B. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Hedayati, Mehdi (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; van Heel, David A. (Blizard Institute, Queen Mary University of London) ; Hirata, Makoto (Institute of Medical Science, The University of Tokyo. Laboratory of Genome Technology) ; Höfer, Imo (University Medical Center Utrecht) ; Hsiung, Chao Agnes (Institute of Population Health Sciences, National Health Research Institutes) ; Huang, Jinyan (Shanghai Institute of Hematology, State Key Laboratory Of Medical Genomics, Rui-jin Hospital, Shanghai Jiao Tong University School of Medicine) ; Hung, Yi-Jen (National Defense Medical Center. School of Medicine) ; Ikram, M. Arfan (Erasmus University Medical Center. Department of Epidemiology) ; Jagadeesan, Anuradha (University of Iceland. Department of Anthropology) ; Jousilahti, Pekka (National Institute for Health and Welfare. Unit of Public Health Promotion) ; Kamatani, Yoichiro (Kyoto University Graduate School of Medicine. Center for Genomic Medicine) ; Kanai, Masahiro (Harvard Medical School. Department of Biomedical Informatics) ; Kerrison, Nicola D. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Kessler, Thorsten (Klinik für Herz- und Kreislauferkrankungen, Technische Universität München. Deutsches Herzzentrum München) ; Khaw, Kay-Tee (University of Cambridge. Department of Public Health and Primary Care) ; Khor, Chiea Chuen (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; de Kleijn, Dominique P. V (University Medical Center Utrecht) ; Koh, Woon-Puay (Duke-NUS Medical School. Health Services and Systems Research) ; Kolcic, Ivana (University of Split. Centre for Global Health, Faculty of Medicine) ; Kraft, Peter (Harvard T.H. Chan School of Public Health. Department of Nutrition) ; Krämer, Bernhard K. (Heidelberg University. Vth Department of Medicine (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim) ; Kutalik, Zoltán (Swiss Institute of Bioinformatics) ; Kuusisto, Johanna (Kuopio University Hospital ( Finlàndia)) ; Langenberg, Claudia (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Launer, Lenore J. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Lawlor, Deborah A. (Population Health Science, Bristol Medical School, Bristol, BS8 2BY UK) ; Lee, I-Te (Chung Shan Medical University, Taichung, Taiwan. School of Medicine) ; Lee, Wen-Jane (Taichung Veterans General Hospital. Department of Medical Research) ; Lerch, Markus M. (University Medicine Greifswald. Department of Internal Medicine A) ; Li, Liming (Peking University Health Science Centre, Peking University. Department of Epidemiology and Biostatistics) ; Liu, Jianjun (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; Loh, Marie (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Biochemistry) ; London, Stephanie J. (National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services) ; Loomis, Stephanie (Johns Hopkins Bloomberg School of Public Health. Department of Epidemiology) ; Lu, Yingchang (Icahn School of Medicine at Mount Sinai (Nova York, Estats Units d'Amèrica)) ; Luan, Jian'an (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Mägi, Reedik (University of Tartu, University of Tartu. Estonian Genome Center) ; Manichaikul, Ani W. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Manunta, Paolo (Genomics of Renal Diseases and Hypertension Unit, IRCCS San Raffaele Scientific Institute, Università Vita Salute San Raffaele, Milano, 20132 Italy) ; Másson, Gísli (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Matoba, Nana (Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Mei, Xue W. (University of Oxford. Nuffield Department of Population Health) ; Meisinger, Christa (Helmholtz Zentrum München, Independent Research Group Clinical Epidemiology, Neuherberg, 85764 Germany) ; Meitinger, Thomas (DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance) ; Mezzavilla, Massimo (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Milani, Lili (Institute of Genomics, University of Tartu. Estonian Genome Center) ; Millwood, Iona Y (University of Oxford. Nuffield Department of Population Health) ; Momozawa, Yukihide (Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Moore, Amy (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Morange, Pierre-Emmanuel (Aix-Marseille University. INSERM UMR_S 1263, Center for CardioVascular and Nutrition research (C2VN)) ; Moreno-Macías, Hortensia (Universidad Autónoma Metropolitana. Departamento de Economía) ; Mori, Trevor A. (The University of Western Australia. Medical School) ; Morrison, Alanna C. (The University of Texas Health Science Center at Houston, School of Public Health, Department of Epidemiology, Human Genetics and Environmental Sciences) ; Muka, Taulant (Institute of Social and Preventive Medicine (ISPM), University of Bern) ; Murakami, Yoshinori (Institute of Medical Science, The University of Tokyo. Division of Molecular Pathology) ; Murray, Alison D. (The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen) ; de Mutsert, Renée (Leiden University Medical Center. Department of Clinical Epidemiology) ; Mychaleckyj, Josyf C. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Nalls, Mike A. (Data Tecnica International LLC, Glen Echo, MD 20812 USA) ; Nauck, Matthias (Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald) ; Neville, Matt J. (Oxford University Hospitals Trust. Oxford NIHR Biomedical Research Centre) ; Nolte, Ilja M. (University of Groningen, University Medical Center Groningen. Department of Epidemiology) ; Ong, Ken K. (University of Cambridge School of Clinical Medicine. Department of Paediatrics) ; Orozco, Lorena (Instituto Nacional de Medicina Genómica) ; Padmanabhan, Sandosh (Institute of Cardiovascular and Medical Sciences, University of Glasgow) ; Pálsson, Gunnar (deCODE genetics/Amgen Inc., Reykjavik, Iceland) ; Pankow, James S. (School of Public Health, University of Minnesota. Division of Epidemiology & Community Health) ; Pattaro, Cristian (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Pattie, Alison (University of Edinburgh. Department of Psychology) ; Polasek, Ozren (Gen-info Ltd, Zagreb, Croatia, Zagreb, Select a Province Croatia) ; Poulter, Neil (Imperial College London, London. Imperial Clinical Trials Unit) ; Pramstaller, Peter P. (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Quintana-Murci, Lluis (Institut Pasteur. Center of Bioinformatics, Biostatistics and Integrative Biology) ; Räikkönen, Katri (University of Helsinki, University of Helsinki. Department of Psychology and Logopedics, Faculty of Medicine) ; Ralhan, Sarju (Hero Heart Institute and Dyanand Medical College and Hospital) ; Rao, Dabeeru C. (Washington University School of Medicine. Division of Biostatistics) ; van Rheenen, Wouter (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Rich, Stephen S. (University of Virginia School of Medicine. Center for Public Health Genomics) ; Ridker, Paul M. (Harvard Medical School) ; Rietveld, Cornelius A. (Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus University Rotterdam) ; Robino, Antonietta (Institute for Maternal and Child Health - IRCCS Burlo Garofolo) ; van Rooij, Frank J. A. (Erasmus University Medical Center. Department of Epidemiology) ; Ruggiero, Daniela (IRCCS Neuromed) ; Saba, Yasaman (Medical University of Graz. Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry) ; Sabanayagam, Charumathi (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ; Sala, Cinzia Felicita (San Raffaele Research Institute, Milano, Italy) ; Salomaa, Veikko (National Institute for Health and Welfare. Department of Public Health Solutions) ; Sandow, Kevin (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Schmidt, Helena (Medical University of Graz. Gottfried Schatz Research Center (for Cell Signaling, Metabolism and Aging), Division of Molecular Biology and Biochemistry) ; Scott, Laura J. (University of Michigan. Department of Biostatistics, and Center for Statistical Genetics) ; Scott, William R. (Imperial College London. Department of Epidemiology and Biostatistics) ; Sedaghati-Khayat, Bahareh (Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Cellular and Molecular Endocrine Research Center) ; Sennblad, Bengt (National Bioinformatics Infrastructure Sweden, Science for Life Laboratory, Uppsala University, Uppsala. Dept of Cell and Molecular Biology) ; van Setten, Jessica (University Medical Center Utrecht) ; Sever, Peter J. (International Centre for Circulatory Health, Imperial College London) ; Sheu, Wayne H-H (Institute of Medical Technology, National Chung-Hsing University) ; Shi, Yuan (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Shrestha, Smeeta (School of Basic and Applied Sciences, Dayananda Sagar University, Bangalore, Karnataka 560078 India) ; Shukla, Sharvari Rahul (Symbiosis Statistical Institute, Symbiosis International University) ; Sigurdsson, Jon K. (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Sikka, Timo Tonis (University of Tartu, University of Tartu. Estonian Genome Center) ; Singh, Jai Rup (Panjab University) ; Smith, Blair H. (Ninewells Hospital and Medical School, University of Dundee. Division of Population Health Sciences) ; Stančáková, Alena (Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland) ; Stanton, Alice (RCSI Molecular & Cellular Therapeutics (MCT), Royal College of Surgeons in Ireland, RCSI Education & Research Centre, Beaumont Hospital, Dublin 9, Ireland) ; Starr, John M. (University of Edinburgh. Alzheimer Scotland Dementia Research Centre) ; Stefansdottir, Lilja (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Straker, Leon (School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University) ; Sulem, Patrick (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Sveinbjornsson, Gardar (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Swertz, Morris A. (Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, 9700 RB The Netherlands) ; Taylor, Adele M. (University of Edinburgh. Department of Psychology) ; Taylor, Kent D. (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Terzikhan, Natalie (Ghent University Hospital. (Bèlgica)) ; Tham, Yih-Chung (Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore) ; Thorleifsson, Gudmar (deCODE genetics/Amgen Inc., Reykjavik 101, Iceland) ; Thorsteinsdottir, Unnur (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Tillander, Annika (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ; Tracy, Russell P. (University of Vermont. Department of Pathology) ; Tusié-Luna, Teresa (Unidad De Biología Molecular y Medicina Genómica, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán) ; Tzoulaki, Ioanna (University of Ioannina Medical School. Department of Hygiene and Epidemiology) ; Vaccargiu, Simona (Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy) ; Vangipurapu, Jagadish (Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland) ; Veldink, Jan (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Vitart, Veronique (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Völker, Uwe (DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, 17475 Germany) ; Vuoksimaa, Eero (Institute for Molecular Medicine Finland (FIMM), University of Helsinki) ; Wakil, Salma M. (King Faisal Specialist Hospital and Research Centre (Aràbia Saudita)) ; Waldenberger, Melanie (Research Unit of Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, 85764 Germany) ; Wander, Gurpreet S. (Hero DMC Heart Institute, Dayanand Medical College & Hospital. Department of Cardiology) ; Wang, Ya Xing (Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Lab) ; Wareham, Nicholas J. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Wild, Sarah (Usher Institute of Population Health and Informatics, University of Edinburgh. Centre for Population Health Sciences) ; Yajnik, Chittaranjan S. (Diabetes Unit, K.E.M. Hospital Research Centre) ; Yuan, Jian-Min (Graduate School of Public Health, University of Pittsburgh. Department of Epidemiology) ; Zeng, Lingyao (Klinik für Herz- und Kreislauferkrankungen, Technische Universität München. Deutsches Herzzentrum München) ; Zhang, Liang (Singapore Eye Research Institute, Singapore National Eye Centre, Singapore) ; Zhou, Jie (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Amin, Najaf (Erasmus University Medical Center. Department of Epidemiology) ; Asselbergs, Folkert W. (Farr Institute of Health Informatics Research and Institute of Health Informatics, University College London) ; Bakker, Stephan J. L. (Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, 9713GZ The Netherlands) ; Becker, Diane M. (Johns Hopkins University School of Medicine. Department of Medicine, GeneSTAR Research Program) ; Lehne, Benjamin (Imperial College London. Department of Epidemiology and Biostatistics) ; Bennett, David A. (Rush University Medical Center. Department of Neurological Sciences) ; van den Berg, Leonard H. (University Medical Centre Utrecht, Utrecht University. Department of Neurology, Brain Centre Rudolf Magnus) ; Berndt, Sonja (National Cancer Institute, National Institutes of Health. Division of Cancer Epidemiology & Genetics) ; Bharadwaj, Dwaipayan (School of Biotechnology, Jawaharlal Nehru University. Systems Genomics Laboratory) ; Bielak, Lawrence F. (University of Michigan. Department of Epidemiology, School of Public Health) ; Bochud, Murielle (University of Lausanne. Center for Primary Care and Public Health (Unisanté)) ; Boehnke, Michael (University of Michigan. Department of Biostatistics, and Center for Statistical Genetics) ; Bouchard, Claude (Pennington Biomedical Research Center) ; Bradfield, Jonathan Paul (Quantinuum Research LLC, San Diego, CA 92101 USA) ; Brody, Jennifer A. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Campbell, Archie (Institute of Genetics & Molecular Medicine, University of Edinburgh. Centre for Genomic & Experimental Medicine) ; Carmi, Shai (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Caulfield, Mark (William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London. Department of Clinical Pharmacology) ; Cesarini, David (Research Institute for Industrial Economics (IFN)) ; Chambers, John C. (Imperial College Healthcare NHS Trust, London) ; Chandak, Giriraj Ratan (CSIR-Centre for Cellular and Molecular Biology. Genomic Research on Complex diseases (GRC Group)) ; Cheng, Ching-Yu (Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Department of Ophthalmology) ; Ciullo, Marina (IRCCS Neuromed) ; Cornelis, Marilyn (Northwestern University Feinberg School of Medicine. Department of Preventive Medicine) ; Cusi, Daniele (Bio4Dreams Scientific Unit, Bio4Dreams SRL, Bio4Dreams - business nursery for life sciences, Milano, 20121 Italy) ; Smith, George Davey (Population Health Science, Bristol Medical School, Bristol, BS8 2BY UK) ; Deary, Ian J. (University of Edinburgh. Department of Psychology) ; Dorajoo, Rajkumar (Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. Human Genetics) ; van Duijn, Cornelia M. (Erasmus University Medical Center. Department of Epidemiology) ; Ellinghaus, David (Christian-Albrechts-University of Kiel. Institute of Clinical Molecular Biology) ; Erdmann, Jeanette (University of Lübeck. Institute for Cardiogenetics) ; Eriksson, Johan G. (Vasa Central Hospital) ; Evangelou, Evangelos (University of Ioannina Medical School. Department of Hygiene and Epidemiology) ; Evans, Michele K. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Faul, Jessica D. (University of Michigan. Institute for Social Research) ; Feenstra, Bjarke (Statens Serum Institut. Department of Epidemiology Research) ; Feitosa, Mary (Washington University School of Medicine. Division of Statistical Genomics, Department of Genetics) ; Foisy, Sylvain (Montreal Heart Institute) ; Franke, Andre (Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel) ; Friedlander, Yechiel (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Gasparini, Paolo (Institute for Maternal and Child Health - IRCCS Burlo Garofolo. Medical Genetics) ; Gieger, Christian (German Center for Diabetes Research (DZD)) ; Gonzalez, Clicerio (Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Publica) ; Goyette, Philippe (Montreal Heart Institute) ; Grant, Struan F. A. (Perelman School of Medicine, University of Pennsylvania. Department of Pediatrics) ; Griffiths, Lyn R. (Institute of Health and Biomedical Innovation, Queensland University of Technology. Genomics Research Centre, School of Biomedical Sciences) ; Groop, Leif (Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Lund University, Skåne University Hospital, Malmö, Sweden) ; Gudnason, Vilmundur (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Gyllensten, Ulf (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Hakonarson, Hakon (University of Pennsylvania. Perelman School of Medicine) ; Hamsten, Anders (Cardiovascular Medicine Unit, Department of Medicine Solna, Centre for Molecular Medicine, Stockholm, 171 76 Sweden) ; van der Harst, Pim (University of Groningen, University Medical Center Groningen, Department of Cardiology, Ther Netherlands) ; Heng, Chew-Kiat (Khoo Teck Puat - National University Children's Medical Institute, National University Health System) ; Hicks, Andrew A. (Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano, 39100 Italy) ; Hochner, Hagit (Hebrew University-Hadassah Medical Center. Braun School of Public Health) ; Huikuri, Heikki (Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital) ; Hunt, Steven C. (University of Utah School of Medicine. Division of Epidemiology, Department of Internal Medicine) ; Jaddoe, Vincent W. V (Erasmus University Medical Center. Department of Pediatrics) ; De Jager, Philip L. (Cell Circuits Program, Broad Institute) ; Johannesson, Magnus (Stockholm School of Economics. Department of Economics) ; Johansson, Åsa (Uppsala University. Department of Immunology, Genetics and Pathology, Science for Life Laboratory) ; Jonas, Jost B. (University of Heidelberg) ; Jukema, J. Wouter (Leiden University Medical Center. Department of Cardiology) ; Junttila, Juhani (Research Unit of Internal Medicine, Medical Research Center Oulu, University of Oulu and Oulu University Hospital) ; Kaprio, Jaakko (University of Helsinki. Department of Public Health) ; Kardia, Sharon L. R. (University of Michigan. Department of Epidemiology, School of Public Health) ; Karpe, Fredrik (Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital) ; Kumari, Meena (Institute for Social and Economic Research, University of Essex) ; Laakso, Markku (Kuopio University Hospital ( Finlàndia)) ; van der Laan, Sander W. (University Medical Center Utrecht) ; Lahti, Jari (University of Helsinki, University of Helsinki. Helsinki Collegium for Advanced Studies) ; Laudes, Matthias (Universitätsklinikum Schleswig-Holstein (Alemanya)) ; Lea, Rodney A. (Institute of Health and Biomedical Innovation, Queensland University of Technology. Genomics Research Centre, School of Biomedical Sciences) ; Lieb, Wolfgang (Institute of Epidemiology and PopGen Biobank, University of Kiel) ; Lumley, Thomas (University of Auckland. Department of Statistics) ; Martin, Nicholas G. (QIMR Berghofer Institute of Medical Research) ; März, Winfried (Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim, Germany) ; Matullo, Giuseppe (University of Turin, Italy. Italian Institute for Genomic Medicine (IIGM) and Dept. Medical Sciences) ; McCarthy, Mark I (Oxford NIHR Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital) ; Medland, Sarah Elizabeth (QIMR Berghofer Institute of Medical Research) ; Merriman, Tony R. (University of Otago. Department of Biochemistry) ; Metspalu, Andres (University of Tartu, University of Tartu. Estonian Genome Center) ; Meyer, Brian F. (King Faisal Specialist Hospital and Research Centre. Department of Genetics) ; Mohlke, Karen L. (University of North Carolina. Department of Genetics) ; Montgomery, Grant W. (Institute for Molecular Bioscience, The University of Queensland) ; Mook-Kanamori, Dennis (Leiden University Medical Center. Department of Public Health and Primary Care) ; Munroe, Patricia B. (Queen Mary University of London. Department of Clinical Pharmacology) ; North, Kari E. (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Nyholt, Dale R. (School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Queensland University of Technology) ; O'connell, Jeffery R. (University of Maryland, School of Medicine. Program for Personalized and Genomic Medicine, Department of Medicine) ; Ober, Carole (University of Chicago. Department of Human Genetics) ; Oldehinkel, Albertine J. (Interdisciplinary Center Psychopathology and Emotion Regulation, University of Groningen, University Medical Center Groningen. Department of Psychiatry) ; Palmas, Walter (Columbia University Medical Center. Department of Medicine) ; Palmer, Colin (Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, The School of Medicine, University of Dundee) ; Pasterkamp, Gerard G. (University Medical Center Utrecht) ; Patin, Etienne (Institut Pasteur. Center of Bioinformatics, Biostatistics and Integrative Biology) ; Pennell, Craig E. (The University of Western Australia. Division of Obstetrics and Gynaecology) ; Pérusse, Louis (Institute of Nutrition and Functional Foods, Laval University) ; Peyser, Patricia A. (University of Michigan. Department of Epidemiology, School of Public Health) ; Pirastu, Mario (Institute of Genetic and Biomedical Research - Support Unity, National Research Council of Italy) ; Polderman, Tinca J. C. (Vrije Universiteit Amsterdam. Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research) ; Porteous, David J. (Institute of Genetics & Molecular Medicine, University of Edinburgh. Centre for Genomic & Experimental Medicine) ; Posthuma, Danielle (Amsterdam Universitair Medische Centra (Amsterdam, Països Baixos)) ; Psaty, Bruce M. (Kaiser Permanente Washington Health Research Institute) ; Rioux, John D. (Université de Montréal. Department of Medicine, Faculty of Medicine) ; Rivadeneira, Fernando (The Generation R Study Group, Erasmus University Medical Center) ; Rotimi, Charles (National Human Genome Research Institute, National Institutes of Health. Center for Research on Genomics and Global Health) ; Rotter, Jerome I (Division of Genomic Outcomes, Department of Pediatrics, The Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA) ; Rudan, Igor (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Den Ruijter, Hester M. (University Medical Center Utrecht) ; Sanghera, Dharambir K. (Oklahoma Center for Neuroscience, Oklahoma City, USA) ; Sattar, Naveed (Institute of Cardiovascular and Medical Sciences, University of Glasgow) ; Schmidt, Reinhold (Medical University of Graz. Clinical Division of Neurogeriatrics, Department of Neurology) ; Schulze, Matthias B. (Institute of Nutritional Sciences, University of Potsdam) ; Schunkert, Heribert (Deutsches Zentrum für Herz- und Kreislauferkrankungen (DZHK), Munich Heart Alliance, Munich, 80636 Germany) ; Scott, Robert A. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Shuldiner, Alan R. (Regeneron Pharmaceuticals, Inc. Regeneron Genetics Center) ; Sim, Xueling (National University of Singapore, Singapore. Saw Swee Hock School of Public Health) ; Small, Neil (University of Bradford. Faculty of Health Studies) ; Smith, Jennifer A. (University of Michigan. Institute for Social Research) ; Sotoodehnia, Nona (University of Washington) ; Tai, E-Shyong (National University of Singapore. Duke-NUS Medical School) ; Teumer, Alexander (University Medicine Greifswald) ; Timpson, Nicholas J. (University of Bristol) ; Toniolo, Daniela (San Raffaele Research Institute, Milano, Italy) ; Tregouet, David-Alexandre (Sorbonne Universités) ; Tuomi, Tiinamaija (University of Helsinki. Research Program of Diabetes and Endocrinology) ; Vollenweider, Peter (Lausanne University Hospital) ; Wang, Carol A. (The University of Western Australia. Division of Obstetrics and Gynaecology) ; Weir, David R. (University of Michigan. Institute for Social Research) ; Whitfield, John B. (QIMR Berghofer Institute of Medical Research) ; Wijmenga, Cisca (University of Groningen. Department of Genetics) ; Wong, Tien-Yin (Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore) ; Wright, John (Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Trust, Bradford, UK) ; Yang, Jingyun (Rush University Medical Center. Department of Neurological Sciences) ; Yu, Lei (Rush University Medical Center. Department of Neurological Sciences) ; Zemel, Babette S. (Children's Hospital of Philadelphia (Pennsilvània)) ; Zonderman, Alan B. (National Institute on Aging, National Institutes of Health. Laboratory of Epidemiology and Population Sciences) ; Perola, Markus (National Institute for Health and Welfare. Unit of Genomics and Biomarkers) ; Magnusson, Patrik K. E. (Karolinska Institutet (Estocolm, Suècia).) ; Uitterlinden, André G. (The Generation R Study Group, Erasmus University Medical Center) ; Kooner, Jaspal S. (Imperial College London) ; Chasman, Daniel I (Harvard Medical School) ; Loos, Ruth J. F. (The Icahn School of Medicine at Mount Sinai. The Mindich Child Health and Development Institute) ; Franceschini, Nora (University of North Carolina. Department of Epidemiology, Gillings School of Global Public Health) ; Franke, Lude (Department of Genetics, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands, Groningen, Groningen, The Netherlands) ; Haley, Chris S. (Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Scotland) ; Hayward, Caroline (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Walters, Robin G. (University of Oxford. Nuffield Department of Population Health) ; Perry, John R. B. (University of Cambridge School of Clinical Medicine. MRC Epidemiology Unit) ; Esko, Tōnu (Broad Institute, Broad Institute. Program in Medical and Population Genetics) ; Helgason, Agnar (University of Iceland. Department of Anthropology) ; Stefansson, Kari (University of Iceland. Faculty of Medicine, School of Health Sciences) ; Joshi, Peter K. (University of Edinburgh. Centre for Global Health Research, Usher Institute) ; Kubo, Michiaki (Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045 Japan) ; Wilson, James F.. (Institute of Genetics and Molecular Medicine, University of Edinburgh. MRC Human Genetics Unit) ; Universitat Autònoma de Barcelona
In many species, the offspring of related parents suffer reduced reproductive success, a phenomenon known as inbreeding depression. In humans, the importance of this effect has remained unclear, partly because reproduction between close relatives is both rare and frequently associated with confounding social factors. [...]
2019 - 10.1038/s41467-019-12283-6
Nature communications, Vol. 10 (october 2019)  

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