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1.
13 p, 1.4 MB Validation of a Meteosat Second Generation solar radiation dataset over the northeastern Iberian Peninsula / Cristóbal, Jordi (Universitat Autònoma de Barcelona. Departament de Geografia) ; Anderson, M. C. (United States Department of Agriculture)
Solar radiation plays a key role in the Earth's energy balance and is used as an essential input data in radiation-based evapotranspiration (ET) models. Accurate gridded solar radiation data at high spatial and temporal resolution are needed to retrieve ET over large domains. [...]
2013 - 10.5194/hess-17-163-2013
Hydrology and earth system sciences, Vol. 17 Issue. 1 (2013) , p. 163-175  
2.
34 p, 16.2 MB Stroke genetics informs drug discovery and risk prediction across ancestries / Mishra, Aniket (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Malik, Rainer (University Hospital, LMU Munich. Institute for Stroke and Dementia Research (ISD)) ; Hachiya, Tsuyoshi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Jürgenson, Tuuli (University of Tartu. Institute of Mathematics and Statistics) ; Namba, Shinichi (Osaka University Graduate School of Medicine. Department of Statistical Genetics) ; Posner, Daniel C. (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Kamanu, Frederick K. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Koido, Masaru (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Le Grand, Quentin (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Shi, Mingyang (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; He, Yunye (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Georgakis, Marios K. (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Caro, Ilana (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Krebs, Kristi (University of Tartu. Estonian Genome Centre, Institute of Genomics) ; Liaw, Yi-Ching (Chung Shan Medical University. Department of Public Health and Institute of Public Health) ; Vaura, Felix C. (Finnish Institute for Health and Welfare. Department of Public Health and Welfare) ; Lin, Kuang (University of Oxford. Nuffield Department of Population Health) ; Winsvold, Bendik Slagsvold (Oslo University Hospital (Oslo, Noruega)) ; Srinivasasainagendra, Vinodh (University of Alabama at Birmingham. Department of Biostatistics, School of Public Health) ; Parodi, Livia (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Bae, Hee-Joon (Seoul National University Bundang Hospital, Seoul National University College of Medicine. Department of Neurology and Cerebrovascular Disease Center) ; Chauhan, Ganesh (Rajendra Institute of Medical Sciences) ; Chong, Michael R. (McMaster University. Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine) ; Tomppo, Liisa (Helsinki University Hospital) ; Akinyemi, Rufus (University of Ibadan. Neuroscience and Ageing Research Unit Institute for Advanced Medical Research and Training, College of Medicine) ; Roshchupkin, Gennady V. (Erasmus MC University Medical Center Rotterdam. Department of Radiology and Nuclear Medicine) ; Habib, Naomi (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences) ; Jee, Yon Ho (Harvard T. H. Chan School of Public Health. Department of Epidemiology) ; Thomassen, Jesper Qvist (Copenhagen University Hospital-Rigshospitalet. Department of Clinical Biochemistry) ; Abedi, Vida (The Pennsylvania State University. Department of Public Health Sciences, College of Medicine) ; Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ; Nygaard, Marianne (Odense University Hospital (Dinamarca)) ; Leonard, Hampton L. (Data Tecnica International) ; Yang, Chaojie (University of Virginia. Department of Biochemistry and Molecular Genetics) ; Yonova-Doing, Ekaterina (Novo Nordisk Research Centre Oxford. Department of Genetics) ; Knol, Maria J. (Erasmus MC University Medical Center Rotterdam. Department of Epidemiology) ; Lewis, Adam J. (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Judy, Renae L. (University of Pennsylvania. Department of Surgery) ; Ago, Tetsuro (Kyushu University. Department of Medicine and Clinical Science, Graduate School of Medical Sciences) ; Amouyel, Philippe (Institut Pasteur de Lille) ; Armstrong, Nicole D. (University of Alabama at Birmingham. Department of Epidemiology) ; Bakker, Mark K. (University Medical Center Utrecht, University Utrecht. UMC Utrecht Brain Center, Department of Neurology and Neurosurgery) ; Bartz, Traci M. (University of Washington. Department of Biostatistics) ; Bennett, David A. (Rush University Medical Center. Rush Alzheimer's Disease Center) ; Bis, Joshua C (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Bordes, Constance (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Børte, Sigrid (Oslo University Hospital. Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research and Innovation, Division of Clinical Neuroscience) ; Cain, Anael (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences) ; Ridker, Paul M. (Harvard Medical School) ; Cho, Kelly (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Chen, Zhengming (University of Oxford. MRC Population Health Research Unit) ; Cruchaga, Carlos (Washington University School of Medicine. NeuroGenomics and Informatics Center) ; Cole, John W. (University of Maryland School of Medicine. Department of Neurology) ; De Jager, Philip L (Columbia University Medical Center. Center for Translational and Computational Neuroimmunology, Department of Neurology) ; de Cid, Rafael (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Endres, Matthias (partner site Berlin. German Centre for Cardiovascular Research (DZHK)) ; Ferreira, Leslie E. (Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil) ; Geerlings, Mirjam I. (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Gasca, Natalie C. (University of Washington. Department of Biostatistics) ; Gudnason, Vilmundur (University of Iceland. Faculty of Medicine) ; Hata, Jun (Kyushu University. Department of Epidemiology and Public Health, Graduate School of Medical Sciences) ; He, Jing (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Heath, Alicia K. (Imperial College London. Department of Epidemiology and Biostatistics, School of Public Health) ; Ho, Yuk-Lam (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Havulinna, Aki S (FIMM-HiLIFE. Institute for Molecular Medicine Finland) ; Hopewell, Jemma C. (University of Oxford. Clinical Trial Service and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health) ; Hyacinth, Hyacinth I. (University of Cincinnati College of Medicine. Department of Neurology and Rehabilitation Medicine) ; Inouye, Michael (University of Cambridge. British Heart Foundation Centre of Research Excellence) ; Jacob, Mina A. (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Jeon, Christina E. (Los Angeles County Department of Public Health) ; Jern, Christina (Sahlgrenska University Hospital (Suècia)) ; Kamouchi, Masahiro (Kyushu University. Department of Health Care Administration and Management, Graduate School of Medical Sciences) ; Keene, Keith L. (East Carolina University. Department of Biology, Brody School of Medicine Center for Health Disparities) ; Kitazono, Takanari (Kyushu University. Department of Medicine and Clinical Science, Graduate School of Medical Sciences) ; Kittner, Steven J. (VA Maryland Health Care System. Department of Neurology and Geriatric Research and Education Clinical Center) ; Konuma, Takahiro (Osaka University Graduate School of Medicine. Department of Statistical Genetics) ; Kumar, Amit (Rajendra Institute of Medical Sciences) ; Lacaze, Paul (Monash University. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine) ; Launer, Lenore Joy (National Institute on Aging, NIH. Intramural Research Program) ; Lee, Keon-Joo (Korea University Guro Hospital. Department of Neurology) ; Lepik, Kaido (University Center for Primary Care and Public Health, Lausanne, Switzerland) ; Li, Jiang (Geisinger Health System. Department of Molecular and Functional Genomics, Weis Center for Research) ; Li, Liming (Peking University Health Science Center. Department of Epidemiology and Biostatistics, School of Public Health) ; Manichaikul, Ani (University of Virginia. Center for Public Health Genomics) ; Markus, Hugh S. (University of Cambridge. Stroke Research Group, Department of Clinical Neurosciences) ; Marston, Nicholas A. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Meitinger, Thomas (German Research Center for Environmental Health. Institute of Human Genetics, Helmholtz Zentrum München) ; Mitchell, Braxton D. (Baltimore Veterans Administration Medical Center. Geriatrics Research and Education Clinical Center) ; Montellano, Felipe A. (University Hospital Würzburg. Department of Neurology) ; Morisaki, Takayuki (The University of Tokyo. Division of Molecular Pathology, Institute of Medical Sciences) ; Mosley, Thomas H. (University of Mississippi Medical Center. The MIND Center) ; Nalls, Mike A. (Data Tecnica International) ; Nordestgaard, Børge G. (University of Copenhagen. Department of Clinical Medicine) ; O'Donnell, Martin J. (NUI Galway. College of Medicine Nursing and Health Science) ; Okada, Yukinori (Osaka University. Center for Infectious Disease Education and Research (CiDER)) ; Onland-Moret, N. Charlotte (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Ovbiagele, Bruce (University of California, San Francisco. Weill Institute for Neurosciences) ; Peters, Annette (German Centre for Cardiovascular Research (DZHK), partner site Munich) ; Psaty, Bruce M. (University of Washington. Department of Health Systems and Population Health) ; Rich, Stephen S. (University of Virginia. Center for Public Health Genomics) ; Rosand, Jonathan (Massachusetts General Hospital. McCance Center for Brain Health) ; Sabatine, Marc S. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Sacco, Ralph L. (Evelyn F. McKnight Brain Institute) ; Saleheen, Danish (Columbia University. Division of Cardiology, Department of Medicine) ; Sandset, Else Charlotte (The Norwegian Air Ambulance Foundation. Research and Development) ; Salomaa, Veikko (Finnish Institute for Health and Welfare. Department of Public Health and Welfare) ; Sargurupremraj, Muralidharan (University of Texas Health Sciences Center. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases) ; Sasaki, Makoto (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Satizabal, Claudia L. (Framingham Heart Study) ; Schmidt, Carsten O. (University Medicine Greifswald, Institute for Community Medicine, SHIP/KEF) ; Shimizu, Atsushi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Smith, Nicholas L. (Seattle Epidemiologic Research and Information Center. Department of Veterans Affairs Office of Research and Development) ; Sloane, Kelly L. (University of Pennsylvania. Department of Neurology) ; Sutoh, Yoichi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Sun, Yan V. (Emory University Rollins School of Public Health. Department of Epidemiology) ; Tanno, Kozo (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Tiedt, Steffen (University Hospital, LMU Munich. Institute for Stroke and Dementia Research (ISD)) ; Tatlisumak, Turgut (Sahlgrenska University Hospital (Suècia)) ; Torres-Aguila, Nuria P.. (Institut d'Investigació Biomèdica Sant Pau) ; Tiwari, Hemant K. (University of Alabama at Birmingham. Department of Biostatistics, School of Public Health) ; Trégouët, David-Alexandre (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Trompet, Stella (Leiden University Medical Center. Department of Cardiology) ; Tuladhar, Anil Man (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Tybjærg-Hansen, Anne (University of Copenhagen. Department of Clinical Medicine) ; van Vugt, Marion (University Medical Center Utrecht, Utrecht University. Division Heart & Lungs, Department of Cardiology) ; Vibo, Riina (University of Tartu. Department of Neurology and Neurosurgery) ; Verma, Shefali S. (University of Pennsylvania. Department of Pathology and Laboratory Medicine) ; Wiggins, Kerri L. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Wennberg, Patrik (Umeå University. Department of Public Health and Clinical Medicine) ; Woo, Daniel (University of Cincinnati College of Medicine. Department of Neurology and Rehabilitation Medicine) ; Wilson, Peter W. F. (Emory University School of Medicine. Department of Medicine, Division of Cardiovascular Disease) ; Xu, Huichun (University of Maryland School of Medicine. Department of Medicine) ; Yang, Qiong (Boston University School of Public Health. Department of Biostatistics) ; Yoon, Kyungheon (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Millwood, Iona Y. (University of Oxford. MRC Population Health Research Unit) ; Gieger, Christian (German Research Center for Environmental Health. Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München) ; Ninomiya, Toshiharu (Kyushu University. Department of Epidemiology and Public Health, Graduate School of Medical Sciences) ; Grabe, Hans J. (German Center for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald) ; Jukema, J. Wouter (LUMC. Einthoven Laboratory for Experimental Vascular Medicine) ; Rissanen, Ina L. (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Strbian, Daniel (Helsinki University Hospital) ; Kim, Young Jin (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Chen, Pei-Hsin (Chung Shan Medical University. Department of Public Health and Institute of Public Health) ; Mayerhofer, Ernst (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Howson, Joanna M. M. (Novo Nordisk Research Centre Oxford. Department of Genetics) ; Irvin, Marguerite R. (University of Alabama at Birmingham. Department of Epidemiology) ; Adams, Hieab (Universidad Adolfo Ibáñez. Latin American Brain Health (BrainLat)) ; Wassertheil-Smoller, Sylvia (Albert Einstein College of Medicine. Department of Epidemiology and Population Health) ; Christensen, Kaare (Odense University Hospital (Dinamarca)) ; Ikram, M. Arfan (Erasmus MC University Medical Center Rotterdam. Department of Epidemiology) ; Rundek, Tatjana (Evelyn F. McKnight Brain Institute) ; Worrall, Bradford B. (University of Virginia. Department of Public Health Science) ; Lathrop, G. Mark (McGill Genome Centre) ; Riaz, Moeen (Monash University. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine) ; Simonsick, Eleanor M. (National Institute on Aging. Longitudinal Studies Section, Translational Gerontology Branch) ; Kõrv, Janika (University of Tartu. Department of Neurology and Neurosurgery) ; França, Paulo H. C. (Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil) ; Zand, Ramin (The Pennsylvania State University. Department of Neurology, College of Medicine) ; Prasad, Kameshwar (Rajendra Institute of Medical Sciences) ; Frikke-Schmidt, Ruth (University of Copenhagen. Department of Clinical Medicine) ; de Leeuw, Frank-Erik (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Liman, Thomas (Carl von Ossietzky University of Oldenburg. Klinik für Neurologie) ; Haeusler, Karl Georg (University Hospital Würzburg. Department of Neurology) ; Ruigrok, Ynte M. (University Medical Center Utrecht, University Utrecht. UMC Utrecht Brain Center, Department of Neurology and Neurosurgery) ; Heuschmann, Peter Ulrich (University Hospital Würzburg. Clinical Trial Center) ; Longstreth, W. T. (University of Washington. Department of Neurology) ; Jung, Keum Ji (Yonsei University. Institute for Health Promotion, Graduate School of Public Health) ; Bastarache, Lisa (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Paré, Guillaume (David Braley Cardiac, Vascular and Stroke Research Institute. Population Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Chasman, Daniel I. (Harvard Medical School) ; Rotter, Jerome I. (The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. The Institute for Translational Genomics and Population Sciences, Department of Pediatrics) ; Anderson, Christopher D. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Zwart, John-Anker (University of Oslo. Institute of Clinical Medicine, Faculty of Medicine) ; Niiranen, Teemu J. (Turku University Hospital. Division of Medicine) ; Fornage, Myriam (University of Texas Health Science Center at Houston. Human Genetics Center, School of Public Health) ; Liaw, Yung-Po (Chung Shan Medical University Hospital. Department of Medical Imaging) ; Seshadri, Sudha (Boston University School of Medicine. Department of Neurology) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Walters, Robin G. (University of Oxford. MRC Population Health Research Unit) ; Ruff, Christian T. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Owolabi, Mayowa O. (University of Ibadan. Department of Medicine) ; Huffman, Jennifer E. (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Milani, Lili (University of Tartu. Estonian Genome Centre, Institute of Genomics) ; Kamatani, Yoichiro (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Dichgans, Martin (German Center for Neurodegenerative Diseases (DZNE)) ; Debette, Stéphanie (CHU de Bordeaux. Department of Neurology, Institute for Neurodegenerative Diseases) ; Universitat Autònoma de Barcelona
Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry ,. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. [...]
2022 - 10.1038/s41586-022-05165-3
Nature, september 2022, p. 1-15  
3.
1 p, 647.1 KB Publisher Correction : Stroke genetics informs drug discovery and risk prediction across ancestries / Mishra, Aniket (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Malik, Rainer (University Hospital, LMU Munich. Institute for Stroke and Dementia Research (ISD)) ; Hachiya, Tsuyoshi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Jürgenson, Tuuli (University of Tartu. Institute of Mathematics and Statistics) ; Namba, Shinichi (Osaka University Graduate School of Medicine. Department of Statistical Genetics) ; Posner, Daniel C. (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Kamanu, Frederick K. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Koido, Masaru (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Le Grand, Quentin (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Shi, Mingyang (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; He, Yunye (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Georgakis, Marios K. (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Caro, Ilana (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Krebs, Kristi (University of Tartu. Estonian Genome Centre, Institute of Genomics) ; Liaw, Yi-Ching (Chung Shan Medical University. Department of Public Health and Institute of Public Health) ; Vaura, Felix C. (Finnish Institute for Health and Welfare. Department of Public Health and Welfare) ; Lin, Kuang (University of Oxford. Nuffield Department of Population Health) ; Winsvold, Bendik Slagsvold (Oslo University Hospital (Oslo, Noruega)) ; Srinivasasainagendra, Vinodh (University of Alabama at Birmingham. Department of Biostatistics, School of Public Health) ; Parodi, Livia (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Bae, Hee-Joon (Seoul National University Bundang Hospital, Seoul National University College of Medicine. Department of Neurology and Cerebrovascular Disease Center) ; Chauhan, Ganesh (Rajendra Institute of Medical Sciences) ; Chong, Michael R. (McMaster University. Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine) ; Tomppo, Liisa (Helsinki University Hospital (Finlàndia)) ; Akinyemi, Rufus (University of Ibadan. Neuroscience and Ageing Research Unit Institute for Advanced Medical Research and Training, College of Medicine) ; Roshchupkin, Gennady V. (Erasmus MC University Medical Center Rotterdam. Department of Radiology and Nuclear Medicine) ; Habib, Naomi (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences) ; Jee, Yon Ho (Harvard T. H. Chan School of Public Health. Department of Epidemiology) ; Thomassen, Jesper Qvist (Copenhagen University Hospital-Rigshospitalet. Department of Clinical Biochemistry) ; Abedi, Vida (The Pennsylvania State University. Department of Public Health Sciences, College of Medicine) ; Cárcel-Márquez, Jara (Universitat Autònoma de Barcelona. Departament de Medicina) ; Nygaard, Marianne (Odense University Hospital (Dinamarca)) ; Leonard, Hampton L. (Data Tecnica International) ; Yang, Chaojie (University of Virginia. Department of Biochemistry and Molecular Genetics) ; Yonova-Doing, Ekaterina (Novo Nordisk Research Centre Oxford. Department of Genetics) ; Knol, Maria J. (Erasmus MC University Medical Center Rotterdam. Department of Epidemiology) ; Lewis, Adam J. (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Judy, Renae L. (University of Pennsylvania. Department of Surgery) ; Ago, Tetsuro (Kyushu University. Department of Medicine and Clinical Science, Graduate School of Medical Sciences) ; Amouyel, Philippe (Institut Pasteur de Lille) ; Armstrong, Nicole D. (University of Alabama at Birmingham. Department of Epidemiology) ; Bakker, Mark K. (University Medical Center Utrecht, University Utrecht. UMC Utrecht Brain Center, Department of Neurology and Neurosurgery) ; Bartz, Traci M. (University of Washington. Department of Biostatistics) ; Bennett, David A. (Rush University Medical Center. Rush Alzheimer's Disease Center) ; Bis, Joshua C. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Bordes, Constance (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Børte, Sigrid (Oslo University Hospital. Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research and Innovation, Division of Clinical Neuroscience) ; Cain, Anael (The Hebrew University of Jerusalem. The Edmond and Lily Safra Center for Brain Sciences) ; Ridker, Paul M. (Harvard Medical School) ; Cho, Kelly (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Chen, Zhengming (University of Oxford. MRC Population Health Research Unit) ; Cruchaga, Carlos (Washington University School of Medicine. NeuroGenomics and Informatics Center) ; Cole, John W. (University of Maryland School of Medicine. Department of Neurology) ; De Jager, Philip L (Columbia University Medical Center. Center for Translational and Computational Neuroimmunology, Department of Neurology) ; de Cid, Rafael (Institut Germans Trias i Pujol) ; Endres, Matthias (partner site Berlin. German Centre for Cardiovascular Research (DZHK)) ; Ferreira, Leslie E. (Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil) ; Geerlings, Mirjam I. (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Gasca, Natalie C. (University of Washington. Department of Biostatistics) ; Gudnason, Vilmundur (University of Iceland. Faculty of Medicine) ; Hata, Jun (Kyushu University. Department of Epidemiology and Public Health, Graduate School of Medical Sciences) ; He, Jing (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Heath, Alicia K. (Imperial College London. Department of Epidemiology and Biostatistics, School of Public Health) ; Ho, Yuk-Lam (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Havulinna, Aki S. (FIMM-HiLIFE. Institute for Molecular Medicine Finland) ; Hopewell, Jemma C. (University of Oxford. Clinical Trial Service and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health) ; Hyacinth, Hyacinth I. (University of Cincinnati College of Medicine. Department of Neurology and Rehabilitation Medicine) ; Inouye, Michael (University of Cambridge. British Heart Foundation Centre of Research Excellence) ; Jacob, Mina A. (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Jeon, Christina E. (Los Angeles County Department of Public Health) ; Jern, Christina (Sahlgrenska University Hospital (Suècia)) ; Kamouchi, Masahiro (Kyushu University. Department of Health Care Administration and Management, Graduate School of Medical Sciences) ; Keene, Keith L. (East Carolina University. Department of Biology, Brody School of Medicine Center for Health Disparities) ; Kitazono, Takanari (Kyushu University. Department of Medicine and Clinical Science, Graduate School of Medical Sciences) ; Kittner, Steven J. (VA Maryland Health Care System. Department of Neurology and Geriatric Research and Education Clinical Center) ; Konuma, Takahiro (Osaka University Graduate School of Medicine. Department of Statistical Genetics) ; Kumar, Amit (Rajendra Institute of Medical Sciences) ; Lacaze, Paul (Monash University. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine) ; Launer, Lenore Joy (National Institute on Aging, NIH. Intramural Research Program) ; Lee, Keon-Joo (Korea University Guro Hospital. Department of Neurology) ; Lepik, Kaido (University Center for Primary Care and Public Health, Lausanne, Switzerland) ; Li, Jiang (Geisinger Health System. Department of Molecular and Functional Genomics, Weis Center for Research) ; Li, Liming (Peking University Health Science Center. Department of Epidemiology and Biostatistics, School of Public Health) ; Manichaikul, Ani (University of Virginia. Center for Public Health Genomics) ; Markus, Hugh S. (University of Cambridge. Stroke Research Group, Department of Clinical Neurosciences) ; Marston, Nicholas A. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Meitinger, Thomas (German Research Center for Environmental Health. Institute of Human Genetics, Helmholtz Zentrum München) ; Mitchell, Braxton D. (Baltimore Veterans Administration Medical Center. Geriatrics Research and Education Clinical Center) ; Montellano, Felipe A. (University Hospital Würzburg. Department of Neurology) ; Morisaki, Takayuki (The University of Tokyo. Division of Molecular Pathology, Institute of Medical Sciences) ; Mosley, Thomas H. (University of Mississippi Medical Center. The MIND Center) ; Nalls, Mike A. (Data Tecnica International) ; Nordestgaard, Børge G. (University of Copenhagen. Department of Clinical Medicine) ; O'Donnell, Martin J. (NUI Galway. College of Medicine Nursing and Health Science) ; Okada, Yukinori (Osaka University. Center for Infectious Disease Education and Research (CiDER)) ; Onland-Moret, N. Charlotte (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Ovbiagele, Bruce (University of California, San Francisco. Weill Institute for Neurosciences) ; Peters, Annette (German Centre for Cardiovascular Research (DZHK), partner site Munich) ; Psaty, Bruce M. (University of Washington. Department of Health Systems and Population Health) ; Rich, Stephen S. (University of Virginia. Center for Public Health Genomics) ; Rosand, Jonathan (Massachusetts General Hospital. McCance Center for Brain Health) ; Sabatine, Marc S. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Sacco, Ralph L. (Evelyn F. McKnight Brain Institute) ; Saleheen, Danish (Columbia University. Division of Cardiology, Department of Medicine) ; Sandset, Else Charlotte (The Norwegian Air Ambulance Foundation. Research and Development) ; Salomaa, Veikko (Finnish Institute for Health and Welfare. Department of Public Health and Welfare) ; Sargurupremraj, Muralidharan (University of Texas Health Sciences Center. Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases) ; Sasaki, Makoto (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Satizabal, Claudia L. (Framingham Heart Study) ; Schmidt, Carsten O. (University Medicine Greifswald, Institute for Community Medicine, SHIP/KEF) ; Shimizu, Atsushi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Smith, Nicholas L. (Seattle Epidemiologic Research and Information Center. Department of Veterans Affairs Office of Research and Development) ; Sloane, Kelly L. (University of Pennsylvania. Department of Neurology) ; Sutoh, Yoichi (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Sun, Yan V. (Emory University Rollins School of Public Health. Department of Epidemiology) ; Tanno, Kozo (Iwate Medical University. Iwate Tohoku Medical Megabank Organization) ; Tiedt, Steffen (University Hospital, LMU Munich. Institute for Stroke and Dementia Research (ISD)) ; Tatlisumak, Turgut (Sahlgrenska University Hospital (Suècia)) ; Torres-Aguila, Nuria P.. (Institut d'Investigació Biomèdica Sant Pau) ; Tiwari, Hemant K. (University of Alabama at Birmingham. Department of Biostatistics, School of Public Health) ; Trégouët, David-Alexandre (University of Bordeaux, Inserm, UMR 1219. Bordeaux Population Health Research Center) ; Trompet, Stella (Leiden University Medical Center. Department of Cardiology) ; Tuladhar, Anil Man (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Tybjærg-Hansen, Anne (University of Copenhagen. Department of Clinical Medicine) ; van Vugt, Marion (University Medical Center Utrecht, Utrecht University. Division Heart & Lungs, Department of Cardiology) ; Vibo, Riina (University of Tartu. Department of Neurology and Neurosurgery) ; Verma, Shefali S. (University of Pennsylvania. Department of Pathology and Laboratory Medicine) ; Wiggins, Kerri L. (University of Washington. Cardiovascular Health Research Unit, Department of Medicine) ; Wennberg, Patrik (Umeå University. Department of Public Health and Clinical Medicine) ; Woo, Daniel (University of Cincinnati College of Medicine. Department of Neurology and Rehabilitation Medicine) ; Wilson, Peter W. F. (Emory University School of Medicine. Department of Medicine, Division of Cardiovascular Disease) ; Xu, Huichun (University of Maryland School of Medicine. Department of Medicine) ; Yang, Qiong (Boston University School of Public Health. Department of Biostatistics) ; Yoon, Kyungheon (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Millwood, Iona Y. (University of Oxford. MRC Population Health Research Unit) ; Gieger, Christian (German Research Center for Environmental Health. Research Unit Molecular Epidemiology, Institute of Epidemiology, Helmholtz Zentrum München) ; Ninomiya, Toshiharu (Kyushu University. Department of Epidemiology and Public Health, Graduate School of Medical Sciences) ; Grabe, Hans J. (German Center for Neurodegenerative Diseases (DZNE), site Rostock/Greifswald) ; Jukema, J. Wouter (LUMC. Einthoven Laboratory for Experimental Vascular Medicine) ; Rissanen, Ina L. (University Medical Center Utrecht, Utrecht University. Department of Epidemiology, Julius Center for Health Sciences and Primary Care) ; Strbian, Daniel (Helsinki University Hospital (Finlàndia)) ; Kim, Young Jin (National Institute of Health. Division of Genome Science, Department of Precision Medicine) ; Chen, Pei-Hsin (Chung Shan Medical University. Department of Public Health and Institute of Public Health) ; Mayerhofer, Ernst (Broad Institute of Harvard and the Massachusetts Institute of Technology. Program in Medical and Population Genetics) ; Howson, Joanna M. M. (Novo Nordisk Research Centre Oxford. Department of Genetics) ; Irvin, Marguerite R. (University of Alabama at Birmingham. Department of Epidemiology) ; Adams, Hieab (Universidad Adolfo Ibáñez) ; Wassertheil-Smoller, Sylvia (Albert Einstein College of Medicine. Department of Epidemiology and Population Health) ; Christensen, Kaare (Odense University Hospital (Dinamarca)) ; Ikram, M. Arfan (Erasmus MC University Medical Center Rotterdam. Department of Epidemiology) ; Rundek, Tatjana (Evelyn F. McKnight Brain Institute) ; Worrall, Bradford B. (University of Virginia. Department of Public Health Science) ; Lathrop, G. Mark (McGill Genome Centre) ; Riaz, Moeen (Monash University. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine) ; Simonsick, Eleanor M. (National Institute on Aging. Longitudinal Studies Section, Translational Gerontology Branch) ; Kõrv, Janika (University of Tartu. Department of Neurology and Neurosurgery) ; França, Paulo H. C. (Post-Graduation Program on Health and Environment, Department of Medicine and Joinville Stroke Biobank, University of the Region of Joinville, Santa Catarina, Brazil) ; Zand, Ramin (The Pennsylvania State University. Department of Neurology, College of Medicine) ; Prasad, Kameshwar (Rajendra Institute of Medical Sciences) ; Frikke-Schmidt, Ruth (University of Copenhagen. Department of Clinical Medicine) ; de Leeuw, Frank-Erik (Radboud University Medical Center. Department of Neurology, Donders Center for Medical Neuroscience) ; Liman, Thomas (Carl von Ossietzky University of Oldenburg. Klinik für Neurologie) ; Haeusler, Karl Georg (University Hospital Würzburg. Department of Neurology) ; Ruigrok, Ynte M. (University Medical Center Utrecht, University Utrecht. UMC Utrecht Brain Center, Department of Neurology and Neurosurgery) ; Heuschmann, Peter Ulrich (University Hospital Würzburg. Clinical Trial Center) ; Longstreth, W. T. (University of Washington. Department of Neurology) ; Jung, Keum Ji (Yonsei University. Institute for Health Promotion, Graduate School of Public Health) ; Bastarache, Lisa (Vanderbilt University Medical Center. Department of Biomedical Informatics) ; Paré, Guillaume (David Braley Cardiac, Vascular and Stroke Research Institute. Population Health Research Institute) ; Damrauer, Scott M. (Corporal Michael Crescenz VA Medical Center) ; Chasman, Daniel I. (Harvard Medical School) ; Rotter, Jerome I. (The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center. The Institute for Translational Genomics and Population Sciences, Department of Pediatrics) ; Anderson, Christopher D. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Zwart, John-Anker (University of Oslo. Institute of Clinical Medicine, Faculty of Medicine) ; Niiranen, Teemu J. (Turku University Hospital. Division of Medicine) ; Fornage, Myriam (University of Texas Health Science Center at Houston. Human Genetics Center, School of Public Health) ; Liaw, Yung-Po (Chung Shan Medical University Hospital. Department of Medical Imaging) ; Seshadri, Sudha (Boston University School of Medicine. Department of Neurology) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Walters, Robin G. (University of Oxford. MRC Population Health Research Unit) ; Ruff, Christian T. (Harvard Medical School. Division of Cardiovascular Medicine, Brigham and Women's Hospital) ; Owolabi, Mayowa O. (University of Ibadan. Department of Medicine) ; Huffman, Jennifer E. (VA Boston Healthcare System. Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC)) ; Milani, Lili (University of Tartu. Estonian Genome Centre, Institute of Genomics) ; Kamatani, Yoichiro (The University of Tokyo. Laboratory of Complex Trait Genomics, Graduate School of Frontier Sciences) ; Dichgans, Martin (German Center for Neurodegenerative Diseases (DZNE)) ; Debette, Stéphanie (CHU de Bordeaux. Department of Neurology, Institute for Neurodegenerative Disease) ; Universitat Autònoma de Barcelona
2022 - 10.1038/s41586-022-05492-5
Nature, Vol. 612 (november 2022) , p. E7  
4.
17 p, 693.0 KB Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke / Jaworek, Thomas ; Xu, Huichun ; Gaynor, Brady ; Cole, John W. ; Rannikmae, Kristiina ; Stanne, Tara M. ; Tomppo, Liisa ; Abedi, Vida ; Amouyel, Philippe ; Armstrong, Nicole D. ; Attia, John ; Bell, Steven ; Benavente, Oscar R. ; Boncoraglio, Giorgio B. ; Butterworth, Adam ; Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ; Chen, Zhengming ; Chong, Michael ; Cruchaga, Carlos ; Cushman, Mary ; Danesh, John ; Debette, Stéphanie ; Duggan, David J. ; Durda, Jon Peter ; Engstrom, Gunnar ; Enzinger, Chris ; Faul, Jessica D. ; Fecteau, Natalie S. ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Gieger, Christian ; Giese, Anne-Katrin ; Grewal, Raji P. ; Grittner, Ulrike ; Havulinna, Aki S. ; Heitsch, Laura ; Hochberg, Marc C. ; Holliday, Elizabeth ; Hu, Jie ; Ilinca, Andreea ; Irvin, Marguerite R. ; Jackson, Rebecca D. ; Jacob, Mina A. ; Rabionet, Raquel ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Johnson, Julie A. ; Kamatani, Yoichiro ; Kardia, Sharon L.R. ; Koido, Masaru ; Kubo, Michiaki ; Lange, Leslie ; Lee, Jin-Moo ; Lemmens, Robin ; Levi, Christopher R. ; Li, Jiang ; Li, Liming ; Lin, Kuang ; Lopez, Haley ; Luke, Sothear ; Maguire, Jane ; McArdle, Patrick F. ; McDonough, Caitrin W. ; Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ; Metso, Tiina ; Müller-Nurasyid, Martina ; Dichgans, Martin ; O'Donnell, Martin ; Peddareddygari, Leema R. ; Pera, Joanna ; Perry, James A. ; Peters, Annette ; Putaala, Jukka ; Ray, Debashree ; Rexrode, Kathryn ; Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rosand, Jonathan ; Rothwell, Peter M. ; Rundek, Tatjana ; Ryan, Kathleen A. ; Sacco, Ralph L. ; Salomaa, Veikko ; Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Schmidt, Reinhold ; Sharma, Pankaj ; Slowik, Agnieszka ; Smith, Jennifer A. ; Smith, Nicholas L. ; Wassertheil-Smoller, Sylvia ; Söderholm, Martin ; Stine, O. Colin ; Strbian, Daniel ; Sudlow, Cathie L.M. ; Tatlisumak, Turgut ; Terao, Chikashi ; Thijs, Vincent ; Torres-Aguila, Nuria P.. ; Trégouët, David-Alexandre ; Tuladhar, Anil M. ; Veldink, Jan ; Walters, Robin G. ; Weir, David R. ; Woo, Daniel ; Worrall, Bradford B. ; Hong, Charles C. ; Ross, Owen A. ; Zand, Ramin ; de Leeuw, Frank-Erik ; Lindgren, Arne G. ; Paré, Guillaume ; Anderson, Christopher D. ; Markus, Hugh S. ; Jern, Christina ; Malik, Rainer ; Dichgans, Martin ; Mitchell, Braxton D. ; Kittner, Steven J. ; Universitat Autònoma de Barcelona
Current genome-wide association studies of ischemic stroke have focused primarily on late-onset disease. As a complement to these studies, we sought to identify the contribution of common genetic variants to risk of early-onset ischemic stroke. [...]
2022 - 10.1212/WNL.0000000000201006
Neurology, Vol. 99 (october 2022) , p. e1738-e1754  
5.
24 p, 1.3 MB Leveraging genetic data to elucidate the relationship between COVID-19 and ischemic stroke / Zuber, Verena (Dementia Research Institute at Imperial College London) ; Cameron, Alan (Institute of Cardiovascular and Medical Sciences. University of Glasgow) ; Myserlis, Evangelos Pavlos (Program in Medical and Population Genetics. Broad Institute of MIT and Harvard) ; Bottolo, Leonardo (Medical Research Council Biostatistics Unit. University of Cambridge) ; Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ; Burgess, Stephen (Department of Public Health and Primary Care. Cardiovascular Epidemiology Unit. University of Cambridge) ; Anderson, Christopher (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ; Dawson, Jesse (Institute of Cardiovascular and Medical Sciences. University of Glasgow) ; Gill, Dipender (Novo Nordisk Research Centre Oxford) ; Universitat Autònoma de Barcelona
BACKGROUND: The relationship between COVID-19 and ischemic stroke is poorly understood due to potential unmeasured confounding and reverse causation. We aimed to leverage genetic data to triangulate reported associations. [...]
2021 - 10.1161/JAHA.121.022433
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 10 Núm. 22 (11 2021) , p. e022433  
6.
26 p, 1.4 MB A systematic global stocktake of evidence on human adaptation to climate change / Berrang-Ford, Lea (University of Leeds. Priestley International Centre for Climate) ; Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Siders, A. R. (University of Delaware. Department of Geography and Spatial Sciences) ; Lesnikowski, Alexandra (Concordia University. Department of Geography, Planning & Environment) ; Paige Fischer, Alexandra (University of Michigan) ; Callaghan, Max W. (University of Leeds. Priestley International Centre for Climate) ; Haddaway, Neal R. (Stockholm Environment Institute) ; Mach, Katharine J. (University of Miami. Department of Environmental Science and Policy) ; Araos, Malcom (New York University. Department of Sociology) ; Rahman Shah, Mohammad Aminur (University of Glasgow) ; Wannewitz, Mia (Ludwig-Maximilians-University Munich. Department of Geography) ; Doshi, Deepal (Ludwig-Maximilians-University Munich. Department of Geography) ; Leiter, Timo (Grantham Research Institute on Climate Change and the Environment) ; Matavel, Custodio (Leibniz-Centre for Agricultural Landscape Research) ; Musah-Surugu, Justice Issah (University of Ghana. Department of Public Administration and Health Service Management) ; Wong-Parodi, Gabrielle (Stanford University. Department of Earth System Science and Woods Institute for the Environment) ; Antwi-Agyei, Philip (Kwame Nkrumah University of Science and Technology. Department of Environmental Science) ; Ajibade, Idowu (Portland State University. Department of Geography) ; Chauhan, Neha (Leuphana University) ; Kakenmaster, William (University of Notre Dame (USA)) ; Grady, Caitlin (Penn State University. Rock Ethics Institute) ; Chalastani, Vasiliki I. (National Technical University of Athens. Department of Water Resources and Environmental Engineering) ; Jagannathan, Kripa (University of Michigan) ; Galappaththi, Eranga K. (McGill University. Department of Geography (Canada)) ; Sitati, Asha (United Nations Office for Disaster Risk Reduction (Switzerland)) ; Scarpa, Giulia (University of Leeds. School of Food and Nutrition) ; Totin, Edmond (Université Nationale d'Agriculture. École de Foresterie Tropicale (Benin)) ; Davis, Katy (University of Leeds. Priestley International Centre for Climate) ; Hamilton, Nikita Charles (NCH Strategy Group (Bahamas)) ; Kirchhoff, Christine J. (University of Connecticut. Department of Civil & Environmental Engineering) ; Kumar, Praveen (Jawaharlal Nehru University) ; Pentz, Brian (University of Toronto Scarborough. Department of Physical and Environmental Sciences) ; Simpson, Nicholas P. (University of Cape Town (South Africa)) ; Theokritoff, Emily (Humboldt-Universität zu Berlin) ; Deryng, Delphine (Humboldt-Universität zu Berlin) ; Reckien, Diana (University of Twente. Department of Urban and Regional Planning and Geo-Information Management) ; Zavaleta-Cortijo, Carol (Universidad Peruana Cayetano Heredia) ; Ulibarri, Nicola (University of California Irvine. Department of Urban Planning & Public Policy) ; Segnon, Alcade C. (University of Abomey-Calavi (Benin)) ; Khavhagali, Vhalinavho (University of Twente. Department of Urban and Regional Planning and Geo-Information Management) ; Shang, Yuanyuan (University of Essex. Department of Government) ; Zvobgo, Luckson (University of Cape Town) ; Zommers, Zinta (United Nations Office for the Coordination of Humanitarian Affairs (USA)) ; Xu, Jiren (University of Glasgow) ; Williams, Portia Adade (Science and Technology Policy Research Institute (Ghana)) ; Villaverde Canosa, Ivan (University of Leeds. Priestley International Centre for Climate) ; van Maanen, Nicole (Climate Analytics (Germany)) ; van Bavel, Bianca (University of Leeds. Priestley International Centre for Climate) ; van Aalst, Maarten (University of Twente. Faculty of Geo-information Science and Earth Observation) ; Turek-Hankins, Lynée L. (University of Miami. Leonard and Jayne Abess Center for Ecosystem Science and Policy) ; Trivedi, Hasti (Maharaja Sayajirao University of Baroda) ; Trisos, Christopher H. (University of Cape Town. African Climate and Development Initiative (South Africa)) ; Thomas, Adelle (University of The Bahamas) ; Thakur, Shinny (G.B. Pant National Institute of Himalayan Environment (India)) ; Templeman, Sienna (Columbia University. Department of Earth and Environmental Sciences) ; Stringer, Lindsay C. (University of York. Department of Environment and Geography) ; Sotnik, Garry (University of Michigan) ; Sjostrom, Kathryn Dana (University of Memphis) ; Singh, Chandni (Indian Institute for Human Settlements) ; Siña, Mariella Z. (Universidad Peruana Cayetano Heredia) ; Shukla, Roopam (Potsdam Institute for Climate Impact Research) ; Salubi, Eunice A. (University of Waterloo) ; Chalkasra, Lolita Shaila Safaee (University of Ottawa. Department of Geography, Environment and Geomatics) ; Ruiz-Díaz, Raquel (Universidade de Vigo. Future Oceans Lab) ; Richards, Carys (University of St. Andrews (Regne Unit)) ; Pokharel, Pratik (Danish Cancer Society Research Centre) ; Petzold, Jan (Ludwig-Maximilians-University Munich. Department of Geography) ; Pelaez Avila, Julia (University of Cape Town (South Africa)) ; Pazmino Murillo, Julia B. (Eberswalde University for Sustainable Development) ; Ouni, Souha (Columbia University) ; Niemann, Jennifer (University of Miami. Rosenstiel School of Marine and Atmospheric Science) ; Nielsen, Miriam (Columbia University. Department of Earth and Environmental Sciences) ; New, Mark (University of Cape Town (South Africa)) ; Schwerdtle, Patricia Nayna (Heidelberg University. Heidelberg Institute of Global Health) ; Nagle Alverio, Gabriela (Duke University. Nicholas School of the Environment) ; Mullin, Cristina A. (University of Connecticut. Department of Civil & Department of Civil & Environmental Engineering) ; Mullenite, Joshua (Wagner College) ; Mosurska, Anuszka (University of Leeds. Priestley International Centre for Climate) ; Morecroft, Mike D. (Natural England) ; Minx, Jan C. (University of Leeds. Priestley International Centre for Climate) ; Maskell, Gina (Potsdam Institute for Climate Impact Research) ; Marshall Nunbogu, Abraham (University of Waterloo. Department of Geography and Environmental Management) ; Magnan, Alexandre (CNRS & University of La Rochelle) ; Lwasa, Shuaib (Makerere University (Uganda)) ; Lukas-Sithole, Megan (University of Cape Town. African Climate and Development Initiative (South Africa)) ; Lissner, Tabea (Climate Analytics (Germany)) ; Lilford, Oliver (Australian National University) ; Koller, Steven F. (University of Miami. Leonard and Jayne Abess Center for Ecosystem Science and Policy) ; Jurjonas, Matthew (The Cooperative Institute for Great Lakes Research (USA)) ; Joe, Elphin Tom (Economics Center. World Resources Institute (India)) ; Huynh, Lam T. M. (University of Tokyo) ; Hill, Avery (Stanford University. Department of Biology) ; Hernandez, Rebecca R. (University of California. Department of Land, Air and Water Resources) ; Hegde, Greeshma (Socratus Foundation for Collective Wisdom (India)) ; Hawxwell, Tom (HafenCity University. Urban Planning and Regional Development) ; Harper, Sherilee (University of Alberta) ; Harden, Alexandra (University of Connecticut) ; Haasnoot, Marjolijn (Utrecht University. Department of Physical Geography) ; Gilmore, Elisabeth A. (Clark University. Department of International Development, Community and Environment) ; Gichuki, Leah (International Livestock Research Institute (Nairobi, Kènia)) ; Gatt, Alyssa (Wilfrid Laurier University) ; Garschagen, Matthias (Ludwig-Maximilians University Munich. Department of Geography) ; Ford, James D. (University of Leeds. Priestley International Centre for Climate) ; Forbes, Andrew (University of Ottawa. Department of Geography, Environment and Geomatics) ; Farrell, Aidan D. (The University of the West Indies-St Augustine Campus (Trinidad and Tobago)) ; Enquist, Carolyn A. F. (United States Geological Survey) ; Elliott, Susan (University of Waterloo. Department of Geography and Environmental Management) ; Duncan, Emily (University of Guelph. Department of Geography, Environment and Geomatics) ; Coughlan de Perez, Erin (Tufts University. Friedman School of Nutrition Science and Policy) ; Coggins, Shaugn (University of Alberta. School of Public Health) ; Chen, Tara (E-DA Hospital (Taiwan)) ; Campbell, Donovan (The University of West Indies (Jamaica)) ; Browne, Katherine E. (Stockholm Environment Institute) ; Bowen, Kathryn J. (University of Melbourne. Melbourne School of Population and Global Health) ; Biesbroek, Robbert (Wageningen University) ; Bhatt, Indra D. (G.B. Pant National Institute of Himalayan Environment (India)) ; Bezner Kerr, Rachel (Cornell University) ; Barr, Stephanie L. (University of Waterloo) ; Baker, Emily (Cornell University) ; Austin, Stephanie E. (Ostbayerische Technische Hochschule Amberg-Weiden) ; Arotoma-Rojas, Ingrid (University of Leeds. Priestley International Centre for Climate) ; Anderson, Christa (WWF (USA)) ; Ajaz, Warda (National University of Sciences and Technology (Pakistan)) ; Agrawal, Tanvi (Ashoka Trust for Research in Ecology and the Environment (India)) ; Zulfawu Abu, Thelma (University of Waterloo. Department of Geography and Environmental Management) ; Sardans i Galobart, Jordi (Centre de Recerca Ecològica i d'Aplicacions Forestals)
Assessing global progress on human adaptation to climate change is an urgent priority. Although the literature on adaptation to climate change is rapidly expanding, little is known about the actual extent of implementation. [...]
2021 - 10.1038/s41558-021-01170-y
Nature Climate Change, Vol. 11 (October 2021) , p. 989-1000  
7.
13 p, 449.0 KB Melflufen and dexamethasone in heavily pretreated relapsed and refractory multiple myeloma / Richardson, Paul G.. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Harvard Medical School) ; Oriol, Albert (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Larocca, Alessandra (Università di Torino. Azienda Ospedaliero-Universitaria Città della Salute e della Scienza) ; Bladé Creixenti, Juan (Hospital Clínic i Provincial de Barcelona) ; Cavo, Michele (Seràgnoli Institute of Hematology. Bologna University School of Medicine) ; Rodriguez-Otero, Paula (Clínica Universidad de Navarra) ; Leleu, Xavier (CHU de Poitiers) ; Nadeem, Omar (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Harvard Medical School) ; Hiemenz, John W. (Division of Hematology-Oncology. Department of Medicine. University of Florida) ; Hassoun, Hani (Memorial Sloan Kettering Cancer Center) ; Touzeau, Cyrille (Université de Nantes) ; Alegre, Adrian (Hospital Universitario de la Princesa (Madrid)) ; Paner, Agne (Rush University Medical Center) ; Maisel, Christopher (Baylor Scott & White Charles A. Sammons Cancer Center) ; Mazumder, Amitabha (Oncology Institute of Hope and Innovation) ; Raptis, Anastasios (Universityof Pittsburgh School of Medicine) ; Moreb, Jan S. (Novant Health Hematology. Novant Health Forsyth Medical Center) ; Anderson, Kenneth C. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Harvard Medical School) ; Laubach, Jacob P. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica). Harvard Medical School) ; Thuresson, Sara (Oncopeptides AB) ; Thuresson, Marcus (Oncopeptides AB) ; Byrne, Catriona (Oncopeptides AB) ; Harmenberg, Johan (Oncopeptides AB) ; Bakker, Nicolaas A. (Oncopeptides AB) ; Mateos, M. V (Hospital Clínico Universitario (Salamanca))
PURPOSE Melphalan flufenamide (melflufen) is a first-in-class peptide-drug conjugate that targets aminopeptidases and rapidly and selectively releases alkylating agents into tumor cells. The phase II HORIZON trial evaluated the efficacy of melflufen plus dexamethasone in relapsed and refractory multiple myeloma (RRMM), a population with an important unmet medical need. [...]
2021 - 10.1200/JCO.20.02259
Journal of Clinical Oncology, Vol. 39 Núm. 7 (january 2021) , p. 757-767  
8.
11 p, 1.9 MB Genetic basis of lacunar stroke : a pooled analysis of individual patient data and genome-wide association studies / Traylor, Matthew (Clinical Pharmacology and The Barts Heart Centre and NIHR Barts Biomedical Research Centre, Barts Health NHS Trust, William Harvey Research Institute, Queen Mary University of London, London, UK) ; Persyn, Elodie (King's College London) ; Tomppo, Liisa (Helsinki University Hospital (Finlàndia)) ; Klasson, Sofia (Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden) ; Abedi, Vida (Department of Molecular and Functional Genomics, Weis Center for Research, Geisinger Health System, Danville, PA, USA) ; Bakker, Mark K. (Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands) ; Torres, Nuria (Institut d'Investigació Biomèdica Sant Pau) ; Li, Linxin (University of Oxford. Nuffield Department of Clinical Neuroscience) ; Bell, Steven (Unversity of Cambridge) ; Rutten-Jacobs, Loes (Product Development Personalized Health Care, F Hoffmann-La Roche, Basel, Switzerland) ; Tozer, Daniel J. (Clinical Neurosciences, University of Cambridge, Cambridge, UK) ; Griessenauer, Christoph J. (Institute of Neurointervention, Paracelsus Medical University, Salzburg, Austria) ; Zhang, Yanfei (Genomic Medicine Institute, Geisinger Health System, Danville, PA, USA) ; Pedersen, Annie (Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden) ; Sharma, Pankaj (Institute of Cardiovascular Research, Royal Holloway University of London, London, UK) ; Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rundek, Tatjana (University of Miami. Miller School of Medicine) ; Grewal, Raji P. (Neuroscience Institute, Saint Francis Medical Center, School of Health and Medical Sciences, Seton Hall University, South Orange, NJ, USA) ; Lindgren, Arne (Lund University (Lund, Suècia)) ; Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ; Salomaa, Veikko (Finnish Institute for Health and Welfare (Helsinki, Finlàndia)) ; Havulinna, Aki S (Institute for Molecular Medicine Finland (FIMM HiLIFE), Helsinki, Finland) ; Kourkoulis, Christina (Program in Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA) ; Crawford, Katherine (Program in Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA) ; Marini, Sandro (Program in Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA) ; Mitchell, Braxton D. (Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA) ; Kittner, Steven J. (Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA) ; Rosand, Jonathan (Program in Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA) ; Dichgans, Martin (Munich Cluster for Systems Neurology (SyNergy), Munich, Germany) ; Jern, Christina (Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden) ; Strbian, Daniel (Helsinki University Hospital (Finlàndia)) ; Fernandez-Cadenas, Israel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Zand, Ramin (Neuroscience Institute, Geisinger Health System, Danville, PA, USA) ; Ruigrok, Ynte (Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, Netherlands) ; Rost, Natalia (Massachusetts General Hospital (Boston)) ; Lemmens, Robin (University Hospitals Leuven (Bèlgica)) ; Rothwell, Peter M. (University of Oxford. Nuffield Department of Clinical Neuroscience) ; Anderson, Christopher D. (Program in Medical & Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA) ; Wardlaw, Joanna (Centre for Clinical Brain Sciences, UK Dementia Research Institute and Row Fogo Centre for Research into the Ageing Brain, University of Edinburgh, Edinburgh, UK) ; Lewis, Cathryn M. (King's College London. Social, Genetic, and Developmental Psychiatry Centre) ; Markus, Hugh S. (Clinical Neurosciences, University of Cambridge, Cambridge, UK) ; Universitat Autònoma de Barcelona
The genetic basis of lacunar stroke is poorly understood, with a single locus on 16q24 identified to date. We sought to identify novel associations and provide mechanistic insights into the disease. [...]
2021 - 10.1016/S1474-4422(21)00031-4
The Lancet neurology, Vol. 20 (may 2021) , p. 351-361  
9.
10 p, 736.9 KB Absolute risk and predictors of the growth of acute spontaneous intracerebral haemorrhage : a systematic review and meta-analysis of individual patient data / Al-Shahi Salman, Rustam (Centre for Clinical Brain Sciences. University of Edinburgh) ; Frantzias, Joseph (King's College Hospital NHS Foundation Trust) ; Lee, Robert J. (Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK) ; Lyden, Patrick D. (Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, California, USA) ; Battey, Thomas W. K. (Massachusetts General Hospital (Boston)) ; Ayres, Alison M. (Massachusetts General Hospital (Boston)) ; Goldstein, Joshua N. (Massachusetts General Hospital (Boston)) ; Mayer, Stephan A. (Department of Neurology, Henry Ford Health System, Detroit, MI, USA) ; Steiner, Thorsten (Heidelberg University Hospital (Alemanya)) ; Wang, Xia (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ; Arima, Hisatomi (The George Institute for Global Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia) ; Hasegawa, Hitoshi (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Oishi, Makoto (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Godoy, Daniel A. (Intensive Care Unit, Hospital Interzonal de Agudos "San Juan Bautista", Catamarca, Argentina) ; Masotti, Luca (Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy) ; Dowlatshahi, Dar (Department of Medicine (Neurology), University of Ottawa and Ottawa Hospital Research Institute, Ottawa, ON, Canada) ; Rodriguez-Luna, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Molina, Carlos A. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jang, Dong-Kyu (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ; Dávalos, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Castillo, José (Complejo Hospitalario Universitario de Santiago de Compostela) ; Yao, Xiaoying (Department of Neurology, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China) ; Claassen, Jan (Department of Neurology, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ; Volbers, Bastian (Bern University Hospital) ; Kazui, Seiji (Kazui Medical Office, Ikeda, Osaka, Japan) ; Okada, Yasushi (Department of Cerebrovascular Medicine and Neurology, National Hospital Organisation Kyushu Medical Centre, Fukuoka, Japan) ; Fujimoto, Shigeru (Division of Neurology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan) ; Toyoda, Kazunori (Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan) ; Li, Qi (Department of Neurology, ThE First Affiliated Hospital of Chongqing Medical University, Chongqing, China) ; Khoury, Jane (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ; Delgado Martínez, María Pilar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Álvarez Sabín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernández-Guillamon, Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Prats-Sánchez, Luis Antonio (Institut d'Investigació Biomèdica Sant Pau) ; Cai, Chunyan (Centre for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, USA) ; Kate, Mahesh P. (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; McCourt, Rebecca (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; Venkatasubramanian, Chitra (Division of Stroke and Neurocritical Care, Stanford University, Palo Alto, CA, USA) ; Diringer, Michael N. (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ; Ikeda, Yukio (Department of Neurosurgery, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan) ; Worthmann, Hans (Department of Neurology, Hannover Medical School, Hannover, Germany) ; Ziai, Wendy C. (Johns Hopkins University School of Medicine, Department of Neurology, Anaesthesia and Critical Care Medicine, Division of Neurocritical Care, Baltimore, MD, USA) ; d'Esterre, Christopher D. (Department of Radiology, Foothills Medical Centre, University of Calgary, Calgary, AB, Canada) ; Aviv, Richard I (Department of Medical Imaging, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada) ; Raab, Peter (Institute of Diagnostic and Interventional Neuroradiology, Hannover Medical School, Hannover, Germany) ; Murai, Yasuo (Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan) ; Zazulia, Allyson R. (Department of Neurology and Neurological Surgery, Washington University, St Louis, MO, USA) ; Butcher, Kenneth S. (Department of Neurology, University of Alberta, Edmonton, AB, Canada) ; Seyedsaadat, Seyed Mohammad (Department of Radiology, Mayo Clinic, Rochester, MN, USA) ; Grotta, James C. (Memorial Hermann Hospital (Houston, Estats Units d'Amèrica)) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Montaner, Joan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Broderick, Joseph P (University of Cincinnati Medical Centre, Cincinnati, OH, USA) ; Yamamoto, Haruko (Center for Advanced Clinical and Translational Sciences, National Cerebral and Cerebrovascular Center, Suita, Osaka, Japan) ; Staykov, Dimitre (Department of Neurology, Hospital of the Brothers of St John, Eisenstadt, Austria) ; Connolly, E. Sander (Department of Neurosurgery, Columbia University, College of Physicians and Surgeons, New York, NY, USA) ; Selim, Magdy (Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA) ; Leira, Rogelio (Complejo Hospitalario Universitario de Santiago de Compostela) ; Moon, Byung Hoo (Department of Neurosurgery, Incheon St Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea) ; Demchuk, Andrew (Department of Clinical Neurosciences and Department of Radiology, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada) ; Di Napoli, Mario (Neurological Service, San Camillo de'Lellis General Hospital, Rieti, Italy) ; Fujii, Yukihiko (Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan) ; Anderson, Craig S.. (The George Institute for Global Health, China at Peking University Health Science Center, Beijing, China) ; Rosand, Jonathan (Massachusetts General Hospital (Boston)) ; Universitat Autònoma de Barcelona
Intracerebral haemorrhage growth is associated with poor clinical outcome and is a therapeutic target for improving outcome. We aimed to determine the absolute risk and predictors of intracerebral haemorrhage growth, develop and validate prediction models, and evaluate the added value of CT angiography. [...]
2018 - 10.1016/S1474-4422(18)30253-9
The Lancet neurology, Vol. 17 (october 2018) , p. 885-894  
10.
13 p, 1.1 MB Skin microdialysis : methods, applications and future opportunities-an EAACI position paper / Baumann, Katrine Y. (RefLab ApS, Copenhagen, Denmark) ; Church, Martin K. (Charité - Universitätsmedizin Berlin) ; Clough, Geraldine F. (University of Southampton) ; Quist, Sven Roy (Otto-von-Guericke University) ; Schmelz, Martin (Heidelberg University) ; Skov, Per Stahl (RefLab ApS, Copenhagen, Denmark) ; Anderson, Chris D. (Linköping University) ; Tannert, Line Kring (Odense University Hospital (Dinamarca)) ; Giménez-Arnau, Ana M 1961- (Universitat Autònoma de Barcelona. Departament de Medicina) ; Frischbutter, Stefan (Charité - Universitätsmedizin Berlin) ; Scheffel, Jörg (Charité - Universitätsmedizin Berlin) ; Maurer, Marcus (Charité - Universitätsmedizin Berlin)
Skin microdialysis (SMD) is a versatile sampling technique that can be used to recover soluble endogenous and exogenous molecules from the extracellular compartment of human skin. Due to its minimally invasive character, SMD can be applied in both clinical and preclinical settings. [...]
2019 - 10.1186/s13601-019-0262-y
Clinical and translational allergy, Vol. 9 (april 2019)  

Articles : 18 registres trobats   1 - 10següent  anar al registre:
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