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Articles, 2 records found
Articles 2 records found  
1.
20 p, 3.7 MB Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation / Li, Yang (Hebei Normal University) ; Shi, Zhenzhen (Kansas State University. Department of Anatomy and Physiology) ; Radauer-Preiml, Isabella (University of Salzburg. Department of Molecular Biology) ; Andosch, Ancuela (University of Salzburg. Department of Molecular Biology) ; Casals Mercadal, Eudald (Vall d'Hebron Institut de Recerca) ; Luetz-Meindl, Ursula (University of Salzburg. Department of Molecular Biology) ; Cobaleda-Siles, Macarena (Vall d'Hebron Institut de Recerca) ; Lin, Zhoumeng (Kansas State University. Department of Anatomy and Physiology) ; Jaberi-Douraki, Majid (Kansas State University. Department of Anatomy and Physiology) ; Italiani, Paola (National Research Council) ; Horejs-Hoeck, Jutta (University of Salzburg. Department of Molecular Biology) ; Himly, Martin (University of Salzburg. Department of Molecular Biology) ; Monteiro-Riviere, Nancy A. (Kansas State University. Department of Anatomy and Physiology) ; Duschl, Albert (University of Salzburg. Department of Molecular Biology) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Boraschi, Diana (National Research Council)
Nanoparticles (NPs) are easily contaminated by bacterial endotoxin (lipopolysaccharide [LPS]). The presence of LPS can be responsible for many immune/inflammatory effects attributed to NPs. In this study, we examined the effects of LPS adsorption on the NP surface on the formation of a biocorona in biological fluids and on the subsequent inflammation-inducing activity of NPs. [...]
2017 - 10.1080/17435390.2017.1401142
Nanotoxicology, Vol. 11, Issue 9-10 (December 2017) , p. 1157-1175  
2.
20 p, 1.9 MB Chitosan functionalisation of gold nanoparticles encourages particle uptake and induces cytotoxicity and pro-inflammatory conditions in phagocytic cells, as well as enhancing particle interactions with serum components / Boyles, Matthew S. P. (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Kristl, Theresa (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Andosch, Ancuela (Paris-Lodron-Universität Salzburg. Department of Cell Biology) ; Zimmermann, Mirjam (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Tran Thi Thanh, Ngoc (Institut Català de Nanotecnologia) ; Casals Mercadal, Eudald (Institut Català de Nanotecnologia) ; Himly, Martin (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Puntes, Víctor (Institut Catala de Recerca i Estudis Avancats) ; Huber, Christian G. (Paris-Lodron-Universität Salzburg. Department of Molecular Biology) ; Lütz-Meindl, Ursula (Paris-Lodron-Universität Salzburg. Department of Cell Biology) ; Duschl, Albert (Paris-Lodron-Universität Salzburg. Department of Molecular Biology)
Gold nanoparticles (AuNPs) are a popular choice for use in medical and biomedical research applications. With suitable functionalisation AuNPs can be applied in drug delivery systems, or can aid in disease diagnosis. [...]
2015 - 10.1186/s12951-015-0146-9
Journal of nanobiotechnology, Vol. 13, Issue 84 (november 2015)  

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