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11 p, 1.0 MB |
Haemophilus parasuis (Glaesserella parasuis) as a Potential Driver of Molecular Mimicry and Inflammation in Rheumatoid Arthritis
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Di Sante, Gabriele (Università Cattolica del Sacro Cuore. Department of Translational Medicine and Surgery) ;
Gremese, Elisa (Università Cattolica del Sacro Cuore. Division of Rheumatology) ;
Tolusso, Barbara (Fondazione Policlinico Universitario Agostino Gemelli-IRCCS. Division of Rheumatology) ;
Cattani, Paola (Università Cattolica del S. Cuore. Dipartimento di Scienze Biotecnologiche di Base) ;
Di Mario, Clara (Università Cattolica del Sacro Cuore. Division of Rheumatology) ;
Marchetti, Simona (Fondazione Policlinico Universitario Agostino Gemelli-IRCCS) ;
Alivernini, Stefano (Fondazione Policlinico Universitario Agostino Gemelli-IRCCS) ;
Tredicine, Maria (Università Cattolica del Sacro Cuore. Department of Translational Medicine and Surgery) ;
Petricca, Luca (Fondazione Policlinico Universitario Agostino Gemelli-IRCCS) ;
Palucci, Ivana (Università Cattolica del S. Cuore. Dipartimento di Scienze Biotecnologiche di Base) ;
Camponeschi, Chiara (Università Cattolica del Sacro Cuore. Department of Translational Medicine and Surgery) ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Gambotto, Andrea (University of Pittsburgh School of Medicine) ;
Ria, Francesco (Fondazione Policlinico Universitario Agostino Gemelli-IRCCS) ;
Ferraccioli, Gianfranco (Università Cattolica del Sacro Cuore)
Background: Haemophilus parasuis (Hps ; now Glaesserella parasuis) is an infectious agent that causes severe arthritis in swines and shares sequence similarity with residues 261-273 of collagen type 2 (Coll), a possible autoantigen in rheumatoid arthritis (RA). [...]
2021 -  10.3389/fmed.2021.671018
Frontiers in Medicine, Vol. 8 (august 2021)
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14 p, 1.3 MB |
Potential of Oral Nanoparticles Containing Cytokines as Intestinal Mucosal Immunostimulants in Pigs : A Pilot Study
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López-Cano, Adrià (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Bach, Àlex (Institució Catalana de Recerca i Estudis Avançats) ;
López-Serrano, Sergi (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Aragon, Virginia (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Blanch, Marta (Lucta S.A. Innovation Division) ;
Pastor, Jose J. (Lucta S.A. Innovation Division) ;
Tedó, Gemma (Lucta S.A. Innovation Division) ;
Morais, Sofia (Lucta S.A. Innovation Division) ;
Garcia-Fruitos, Elena (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal) ;
Arís i Giralt, Anna (Unitat mixta d'investigació IRTA-UAB en Sanitat Animal. Centre de Recerca en Sanitat Animal)
Antibiotics are essential compounds to cope with bacterial infections. However, their inadequate and excessive use has triggered the rapid arising of antimicrobial-resistant bacteria. In this scenario, immunostimulants, which are molecules that boost the immune system, open up a new approach to face this problem, enhancing treatment efficacy and preventing infections by immune system response. [...]
2022 - 10.3390/ani12091075
Animals, Vol. 12 (april 2022)
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3.
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15 p, 5.1 MB |
Piglet innate immune response to Streptococcus suis colonization is modulated by the virulence of the strain
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Neila-Ibáñez, Carlos María (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Brogaard, Louise (University of Copenhagen.Department of Veterinary and Animal Sciences) ;
Pailler-García, Lola (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Martínez Martínez, Jorge (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Segura, Mariela (University of Montreal. Research Group On Infectious Diseases in Production Animals and Swine and Poultry Infectious Diseases Research Centre) ;
Heegaard, Peter M. H. (Technical University of Denmark. Innate Immunology Group) ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Streptococcus suis is a zoonotic pathogen of swine involved in arthritis, polyserositis, and meningitis. Colonization of piglets by S. suis is very common and occurs early in life. The clinical outcome of infection is influenced by the virulence of the S. [...]
2021 - 10.1186/s13567-021-01013-w
Veterinary research, Vol. 52 (december 2021)
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4.
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13 p, 1.7 MB |
Longitudinal Study of Fecal Microbiota in Calves with or without Diarrhea Episodes before Weaning
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Obregon-Gutierrez, Pau (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Bague-Companys, Jaume (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Bach, Àlex (Institució de Recerca i Estudis Avançats) ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Correa-Fiz, Florencia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Animal production is searching for ways to reduce antimicrobial use, and the best way is to avoid their use by maintaining the health of the animals. The microbiota is involved in the host health, and when the fecal microbiota was analyzed in calves that developed or not diarrhea, differences linked to the health status were detected. [...]
2022 - 10.3390/vetsci9090463
Veterinary Sciences, Vol. 9 (august 2022)
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12 p, 1.4 MB |
First Report of Streptococcus ruminantium in Wildlife : phenotypic Differences with a Spanish Domestic Ruminant Isolate
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Neila-Ibáñez, Carlos María (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Pintado, Ester (Universitat Autònoma de Barcelona. Servei de Diagnòstic de Patologia Veterinària) ;
Velarde, Roser (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Fernández Aguilar, Xavier (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge) ;
Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Abarca Salat, Maria Lourdes (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Streptococcus ruminantium is a recent reclassification of the former Streptococcus suis serovar 33. Although knowledge about S. suis is extensive, information on S. ruminantium host range and pathogenic potential is still scarce. [...]
2022 - 10.3390/microbiolres13010008
Microbiology Research, Vol. 13 Núm. 1 (2022) , p. 102-113
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10 p, 1.0 MB |
Molecular characterization of Glaesserella parasuis strains isolated from North America, Europe and Asia by serotyping PCR and LS-PCR
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Macedo, Nubia (Iowa State University. Veterinary Diagnostic Laboratory) ;
Gottschalk, Marcelo (University of Montreal. Faculty of Veterinary Medicine) ;
Strutzberg-Minder, Katrin (Innovative Veterinary Diagnostics) ;
Van, Chao Nguyen (Huazhong Agricultural University College of Veterinary Medicine. State Key Laboratory of Agricultural Microbiology) ;
Zhang, Lijun (Huazhong Agricultural University College of Veterinary Medicine. State Key Laboratory of Agricultural Microbiology) ;
Zou, Geng (Huazhong Agricultural University College of Veterinary Medicine. State Key Laboratory of Agricultural Microbiology) ;
Zhou, Rui (Huazhong Agricultural University College of Veterinary Medicine. State Key Laboratory of Agricultural Microbiology) ;
Marostica, Thaire (Federal University of Minas Gerais. Department of Veterinary Clinic and Surgery) ;
Clavijo, Maria Jose (PIC North America) ;
Tucker, Alexander (University of Cambridge. Department of Veterinary Medicine) ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
Glaesserella parasuis strains were characterized by serotyping PCR, vtaA virulence marker Leader Sequence (LS)-PCR, clinical significance, and geographic region. Overall, the serovars 4, 5/12, 7, 1, and 13 were the most commonly detected. [...]
The online version contains supplementary material available at 10. 1186/s13567-021-00935-9.
2021 - 10.1186/s13567-021-00935-9
Veterinary research, Vol. 52 (may 2021)
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18 p, 1.9 MB |
The use of genome wide association methods to investigate pathogenicity, population structure and serovar in Haemophilus parasuis
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Howell, Kate J. (University of Cambridge. Department of Veterinary Medicine) ;
Weinert, Lucy A. (University of Cambridge. Department of Veterinary Medicine) ;
Chaudhuri, Roy R. (University of Sheffield. Department of Molecular Biology and Biotechnology) ;
Luan, Shi-Lu (University of Cambridge. Department of Veterinary Medicine) ;
Peters, Sarah E. (University of Cambridge. Department of Veterinary Medicine) ;
Corander, Jukka (University of Helsinki. Department of Mathematics and Statistics) ;
Harris, David (The Wellcome Trust Sanger Institute) ;
Angen, Øystein (Norwegian Veterinary Institute) ;
Aragon, Virginia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Bensaid, Albert (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Williamson, Susanna M. (Animal Health and Veterinary Laboratories Agency) ;
Parkhill, Julian (The Wellcome Trust Sanger Institute) ;
Langford, Paul R. (Imperial College London. Department of Medicine, Section of Paediatrics) ;
Rycroft, Andrew N. (The Royal Veterinary College) ;
Wren, Brendan W. (London School of Hygiene & Tropical Medicine. Faculty of Infectious & Tropical Diseases) ;
Holden, Matthew T. G. (University of St. Andrews. School of Medicine) ;
Tucker, Alexander W. (University of Cambridge. Department of Veterinary Medicine) ;
Maskell, Duncan J. (University of Cambridge. Department of Veterinary Medicine)
Haemophilus parasuis is the etiologic agent of Glässer's disease in pigs and causes devastating losses to the farming industry. Whilst some hyper-virulent isolates have been described, the relationship between genetics and disease outcome has been only partially established. [...]
2014 - 10.1186/1471-2164-15-1179
BMC genomics, Vol. 15 (december 2014)
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