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7 p, 963.1 KB |
Gut microbiota signature in treatment-naïve attention-deficit/hyperactivity disorder
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Richarte, Vanesa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Corrales, Montserrat (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fadeuilhe, Christian (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arribas, Lorena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-Estela, Aitana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosales-Ortiz, Silvia Karina (Universitat de Barcelona. Departament de Biomedicina) ;
Arias-Vásquez, Alejandro (Radboud University Medical Center) ;
Soler Artigas, María (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Ribasés Haro, Marta (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Compelling evidence supports alterations in gut microbial diversity, bacterial composition, and/or relative abundance of several bacterial taxa in attention-deficit/hyperactivity disorder (ADHD). However, findings for ADHD are inconsistent among studies, and specific gut microbiome signatures for the disorder remain unknown. [...]
2021 -  10.1038/s41398-021-01504-6
Translational psychiatry, Vol. 11 (july 2021)
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11 p, 912.1 KB |
Identification of ADHD risk genes in extended pedigrees by combining linkage analysis and whole-exome sequencing
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Corominas Galbany, Jordi (Radboud University Medical Center) ;
Klein, Marieke (Radboud University Medical Center) ;
Zayats, Tetyana (University of Bergen) ;
Rivero, Olga (University of Würzburg) ;
Ziegler, Georg C. (University of Würzburg) ;
Pauper, Marc (Radboud University Medical Center) ;
Neveling, Kornelia (Radboud University Medical Center) ;
Poelmans, Geert (Radboud University Medical Center) ;
Jansch, Charline (University of Würzburg) ;
Svirin, Evgeniy (I.M. Sechenov First Moscow State Medical University) ;
Geissler, Julia (University Hospital of Würzburg) ;
Weber, Heike (University Hospital of Frankfurt (Alemanya)) ;
Reif, Andreas (University Hospital of Frankfurt (Alemanya)) ;
Arias-Vásquez, Alejandro (Radboud University Medical Center) ;
Galesloot, Tessel E. (Radboud University Medical Center) ;
Kiemeney, Lambertus A. L. M. (Radboud University Medical Center) ;
Buitelaar, Jan (Radboud University Medical Center) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Hveem, Kristian (Norwegian University of Science and Technology) ;
Gabrielsen, Maiken Elvestad (Norwegian University of Science and Technology) ;
Hoffmann, Per (University of Basel) ;
Cichon, Sven (University Hospital Basel (Basilea, Suïssa)) ;
Haavik, Jan (Haukeland University Hospital (Bergen, Noruega)) ;
Johansson, Stefan E (University of Bergen) ;
Jacob, Christian P. (University of Würzburg) ;
Romanos, Marcel (University Hospital of Würzburg) ;
Franke, Barbara (Radboud University Medical Center) ;
Lesch, Klaus-Peter (Maastricht University)
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder with a complex genetic background, hampering identification of underlying genetic risk factors. We hypothesized that combining linkage analysis and whole-exome sequencing (WES) in multi-generation pedigrees with multiple affected individuals can point toward novel ADHD genes. [...]
2018 - 10.1038/s41380-018-0210-6
Molecular psychiatry, Vol. 25 (august 2018) , p. 2047-2057
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10 p, 2.1 MB |
Shared genetic background between children and adults with attention deficit/hyperactivity disorder
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Rovira, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Demontis, Ditte (Center for Genomics and Personalized Medicine, Aarhus, Denmark) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Zayats, Tetyana (Broad Institute of MIT and Harvard) ;
Klein, Marieke (University Medical Center Utrecht) ;
Mota, Nina Roth (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Weber, Heike (University Hospital of Frankfurt (Alemanya)) ;
García-Martinez, Iris (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pagerols, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arribas, Lorena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Richarte, Vanesa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corrales, Montserrat (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Fadeuilhe, Christian (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Bosch, Rosa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Martin, Gemma Español (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Almos, Peter (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Doyle, Alysa E. (Harvard Medical School. Department of Psychiatry) ;
Grevet, Eugenio Horacio (Universidade Federal do Rio Grande do Sul. Department of Psychiatry, Faculty of Medicine) ;
Grimm, Oliver (University Hospital of Frankfurt (Alemanya)) ;
Halmøy, Anne (Haukeland University Hospital (Bergen, Noruega)) ;
Hoogman, Martine (Radboud University Medical Center. Department of Human Genetics, Donders Institute for Brain, Cognition, and Behaviour) ;
Hutz, Mara (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Jacob, Christian P. (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Kittel-Schneider, Sarah (University Hospital of Frankfurt (Alemanya)) ;
Knappskog, Per M. (University of Bergen. Department of Clinical Science) ;
Lundervold, Astri J. (University of Bergen. Department of Biological and Medical Psychology) ;
Rivero, Olga (University of Würzburg. Division of Molecular Psychiatry, Center of Mental Health) ;
Rovaris, Diego Luiz (University of São Paulo. Department of Physiology and Biophysics, Institute of Biomedical Sciences) ;
Salatino-Oliveira, Angelica (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
da Silva, Bruna Santos (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Svirin, Evgeniy (IM Sechenov First Moscow State Medical University. Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine) ;
Sprooten, Emma (Radboud University Medical Centre. Department of Cognitive Neuroscience) ;
Strekalova, Tatyana (Maastricht University. Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS)) ;
Arias-Vásquez, Alejandro (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Sonuga-Barke, Edmund J. S. (Aarhus University. Department of Child and Adolescent Psychiatry) ;
Asherson, Philip (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Bau, Claiton Henrique Dotto (Universidade Federal do Rio Grande do Sul. Department of Genetics, Institute of Biosciences) ;
Buitelaar, Jan (Karakter Child and Adolescent Psychiatry, Nijmegen, The Netherlands) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Faraone, Stephen V. (SUNY Upstate Medical University. Departments of Psychiatry, of Neuroscience, and Physiology) ;
Haavik, Jan (Haukeland University Hospital (Bergen, Noruega)) ;
Johansson, Stefan E. (University of Bergen. Department of Clinical Science) ;
Kuntsi, Jonna (King's College London. Institute of Psychiatry, Psychology & Neuroscience) ;
Larsson, Henrik (Karolinska Institutet (Estocolm, Suècia). Department of Medical Epidemiology and Biostatistics) ;
Lesch, Klaus-Peter (Maastricht University. Department of Neuroscience, School for Mental Health and Neuroscience (MHeNS)) ;
Reif, Andreas (University Hospital of Frankfurt (Alemanya)) ;
Rohde, Luis Augusto (Hospital de Clínicas de Porto Alegre (Brasil)) ;
Casas Brugué, Miquel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Børglum, Anders D. (Center for Genomics and Personalized Medicine, Aarhus, Denmark) ;
Franke, Barbara (Radboud University Medical Center. Department of Psychiatry, Donders Institute for Brain, Cognition, and Behaviour) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Attention deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by age-inappropriate symptoms of inattention, impulsivity, and hyperactivity that persist into adulthood in the majority of the diagnosed children. [...]
2020 - 10.1038/s41386-020-0664-5
Neuropsychopharmacology, Vol. 45 (april 2020) , p. 1617-1626
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12 p, 694.9 KB |
Treating impulsivity with probiotics in adults (PROBIA) : study protocol of a multicenter, double-blind, randomized, placebo-controlled trial
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Arteaga-Henríquez, Gara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosales, Silvia Karina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Arias-Vásquez, Alejandro (Radboud University Medical Centre. Department of Psychiatry) ;
Bitter, Istvan (Semmelweis University. Department of Psychiatry and Psychotherapy) ;
Ginsberg, Ylva (Karolinska Institutet (Estocolm, Suècia). Department of Clinical Neuroscience) ;
Ibáñez, Pol (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Kilencz, Tünde (Semmelweis University. Department of Psychiatry and Psychotherapy) ;
Lavebratt, Catharina (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Matura, Silke (Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt, Germany) ;
Reif, Andreas (Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt, Germany) ;
Rethelyi, Janos (Semmelweis University. Department of Psychiatry and Psychotherapy) ;
Richarte, Vanesa (Hospital Universitari Vall d'Hebron) ;
Rommelse, Nanda (Karakter Child and Adolescent Psychiatry University Centre) ;
Siegl, Anne (Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital, Goethe University, Frankfurt, Germany) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Impulsivity and compulsivity are related to emotional and social maladjustment and often underlie psychiatric disorders. Recently, alterations in microbiota composition have been shown to have implications for brain development and social behavior via the microbiota-gut-brain axis. [...]
2020 - 10.1186/s13063-019-4040-x
Trials, Vol. 21 (february 2020)
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18 p, 732.6 KB |
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
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Guadalupe, Tulio (International Max Planck Research School for Language Sciences (Nijmegen, Països Baixos)) ;
Mathias, Samuel R. ;
vanErp, Theo G. M. ;
Whelan, Christopher D. ;
Zwiers, Marcel P ;
Abe, Yoshinari ;
Abramovic, Lucija ;
Agartz, Ingrid ;
Andreassen, Ole A. ;
Arias-Vásquez, Alejandro ;
Aribisala, Benjamin S. ;
Armstrong, Nicola ;
Arolt, Volker ;
Artiges, Eric (University Paris Descartes -Sorbonne Paris Cité (París, França)) ;
Ayesa-Arriola, Rosa (Centro de Investigación Biomédica en Red de Salud Mental) ;
Baboyan, Vatche G. ;
Banaschewski, Tobias ;
Barker, Gareth ;
Bastin, Mark E. ;
Baune, Bernhard T. ;
Blangero, John ;
Bokde, Arun L. W. ;
Boedhoe, Premika (Neuroscience Campus Amsterdam, Amsterdam, The Netherlands) ;
Bose, Anushree ;
Brem, Silvia ;
Brodaty, Henry ;
Bromberg, Uli ;
Brooks, Samantha ;
Büchel, Christian ;
Buitelaar, Jan ;
Calhoun, Vince ;
Cannon, Dara M. ;
Cattrell, Anna ;
Cheng, Yuqi ;
Conrod, Patricia ;
Conzelmann, Annette ;
Corvin, Aiden ;
Crespo-Facorro, Benedicto (Centro de Investigación Biomédica en Red de Salud Mental) ;
Crivello, Fabrice ;
Dannlowski, Udo ;
de Zubicaray, Greig ;
De Zwarte, Sonja M. C. ;
Deary, Ian J. ;
Desrivières, Sylvane ;
Doan, Nhat Trung ;
Donohoe, Gary ;
Dørum, Erlend S. ;
Ehrlich, Stefan ;
Espeseth, Thomas ;
Fernández, Guillén (Raboud University, Nijmegen, The Netherlands) ;
Flor, Herta ;
Fouche, Jean-Paul ;
Frouin, Vincent ;
Fukunaga, Masaki ;
Gallinat, Jürgen ;
Garavan, Hugh P ;
Gill, Michael ;
Suarez, Andrea Gonzalez ;
Gowland, Penny ;
Grabe, Hans J. (HELIOS Hospital Stralsund (Stralsund, Alemanya)) ;
Grotegerd, Dominik ;
Gruber, Oliver ;
Hagenaars, Saskia ;
Hashimoto, Ryota ;
Hauser, Tobias U. (University College London) ;
Heinz, Andreas ;
Hibar, Derrek P. ;
Hoekstra, Pieter J. (University of Groningen. Department of Psychiatry) ;
Hoogman, Martine ;
Howells, Fleur M. ;
Hu, Hao ;
Hulshoff Pol, Hilleke E. ;
Huyser, Chaim ;
Ittermann, Bernd ;
Jahanshad, Neda ;
Jönsson, Erik G. ;
Jurk, Sarah ;
Kahn, Rene S. ;
Kelly, Sinead ;
Kraemer, Bernd ;
Kugel, Harald ;
Kwon, Jun Soo ;
Lemaitre, Herve (Institut National de la Santé et de la Recherche Médicale (Paris, França)) ;
Lesch, Klaus-Peter ;
Lochner, Christine (University of Stellenbosch. Department of Psychiatry) ;
Luciano, Michelle ;
Marquand, Andre F. ;
Martin, Nicholas G. ;
Martínez-Zalacaín, Ignacio (Hospital Universitari de Bellvitge) ;
Martinot, Jean-Luc ;
Mataix-Cols, David ;
Mather, Karen A ;
McDonald, Colm ;
McMahon, Katie L. ;
Medland, Sarah Elizabeth ;
Menchón Magriñá, José Manuel (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Morris, Derek W. ;
Mothersill, Omar ;
Maniega, Susana Munoz ;
Mwangi, Benson ;
Nakamae, Takashi ;
Nakao, Tomohiro ;
Narayanaswaamy, Janardhanan C. ;
Nees, Frauke ;
Nordvik, Jan E. ;
Onnink, A. Marten H. ;
Opel, Nils ;
Ophoff, Roel ;
Paillère Martinot, Marie-Laure ;
Papadopoulos Orfanos, Dimitri ;
Pauli, Paul ;
Paus, Tomáš ;
Poustka, Luise ;
Reddy, Janardhan YC. ;
Rentería, Miguel E. ;
Roiz-Santiáñez, Roberto (Centro de Investigación Biomédica en Red de Salud Mental) ;
Roos, Annerine (University of Stellenbosch. Department of Psychiatry) ;
Royle, Natalie A. ;
Sachdev, Perminder ;
Sánchez-Juan, Pascual (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Schmaal, Lianne ;
Schumann, Gunter ;
Shumskaya, Elena ;
Smolka, Michael N. ;
Soares, Jair C. ;
Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Stein, Dan J. (University of Cape Town. Department of Psychiatry) ;
Strike, Lachlan ;
Toro, Roberto ;
Turner, Jessica A. ;
Tzourio-Mazoyer, Nathalie ;
Uhlmann, Anne ;
Hernández, Maria Valdés ;
van den Heuvel, Odile A. (Neuroscience Campus Amsterdam, VU/VUMC, Amsterdam, The Netherlands) ;
van der Meer, Dennis (University of Groningen. Department of Psychiatry) ;
van Haren, Neeltje E. M. ;
Veltman, Dick J. ;
Venkatasubramanian, Ganesan ;
Vetter, Nora C. ;
Vuletic, Daniella ;
Walitza, Susanne ;
Walter, Henrik ;
Walton, Esther ;
Wang, Zhen ;
Wardlaw, Joanna ;
Wen, Wei ;
Westlye, Lars T. ;
Whelan, Robert ;
Wittfeld, Katharina (Site Rostock, Greifswald, Germany) ;
Wolfers, Thomas (Raboud University, Nijmegen, The Netherlands) ;
Wright, Margaret J. ;
Xu, Jian ;
Xu, Xiufeng ;
Yun, Je-Yeon ;
Zhao, JingJing ;
Franke, Barbara ;
Thompson, Paul M. ;
Glahn, David C. (Olin Neuropsychiatric Research Center (Estats Units)) ;
Mazoyer, Bernard ;
Fisher, Simon E. (Raboud University) ;
Francks, Clyde (Donders Institute for Brain, Cognition and Behaviour, Raboud University, Nijmegen, The Netherlands)
The online version of this article (doi:10. 1007/s11682-016-9629-z) contains supplementary material, which is available to authorized users.
2016 - 10.1007/s11682-016-9629-z
Brain Imaging and Behavior, Vol. 11 (october 2016) , p. 1497-1514
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