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69 p, 3.0 MB Genomic characterisation of brain malignancies through liquid biopsies: The cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma / Arruda, Letícia de Mattos ; Seoane, Joan, dir. ; Cortes, Javier, dir. ; Bosch Gil, Josep Angel, dir. ; Universitat Autònoma de Barcelona. Departament de Medicina
Los recientes avances en la secuenciación masiva en paralelo y en las técnicas genómicas digitales apoyan la validez clínica del ADN libre tumoral circulante (ctDNA) como una "biopsia líquida" en el cáncer humano. [...]
Recent developments in massively parallel sequencing and digital genomic techniques support the clinical validity of cell-free circulating tumour DNA (ctDNA) as a ‘liquid biopsy' in human cancer. ctDNA in plasma may be useful to identify actionable genomic alterations, monitor treatment responses, unravel therapeutic resistance, and potentially to characterise tumour heterogeneity. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2016  

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