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13 p, 561.5 KB Gene fusions derived by transcriptional readthrough are driven by segmental duplication in human / McCartney, Ann M. (Dublin City University. Bioinformatics and Molecular Evolution Group) ; Hyland, Edel M. (Queens University Belfast. Institute for Global Food Security) ; Cormican, Paul (Animal and Grassland Research and Innovation Centre (Irlanda)) ; Moran, Raymond J. (Dublin City University. Bioinformatics and Molecular Evolution Group) ; Webb, Andrew E. (Dublin City University. Bioinformatics and Molecular Evolution Group) ; Lee, Kate D. (Massey University (New Zealand)) ; Hernandez Rodriguez, Jessica (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Prado-Martinez, Javier (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona)) ; Creevey, Christopher J. (Aberystwyth University. Institute of Biological, Environmental and Rural Sciences) ; Aspden, Julie L. (University of Leeds. School of Molecular and Cellular Biology) ; McInerney, James O. (University of Nottingham. School of Life Sciences) ; Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont) ; O'Connell, Mary J. (University of Nottingham. School of Life Sciences)
Gene fusion occurs when two or more individual genes with independent open reading frames becoming juxtaposed under the same open reading frame creating a new fused gene. A small number of gene fusions described in detail have been associated with novel functions, for example, the hominid-specific PIPSL gene, TNFSF12, and the TWE-PRIL gene family. [...]
2019 - 10.1093/gbe/evz163
Genome biology and evolution, Vol. 11, Issue 9 (September 2019) , p. 2678-2690  
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