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Articles, 1 records found
Articles 1 records found  
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8 p, 592.8 KB Undifferentiated and differentiated PC12 cells protected by huprines against injury induced by hydrogen peroxide / Pera Muñoz, Marta (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Camps García, Pelayo (Universitat de Barcelona. Laboratori de Química Farmaceùtica) ; Muñoz-Torrero López-Ibarra, Diego (Universitat de Barcelona. Laboratori de Química Farmaceùtica) ; Pérez Fernández, Belén (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Badia Sancho A. (Albert) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Clos Guillén, Victoria (Universitat Autònoma de Barcelona. Institut de Neurociències)
Oxidative stress is implicated in the pathogenesis of neurodegenerative disorders and hydrogen peroxide (H₂O₂) plays a central role in the stress. Huprines, a group of potent acetylcholinesterase inhibitors (AChEIs), have shown a broad cholinergic pharmacological profile. [...]
2013 - 10.1371/journal.pone.0074344
PLoS One, Vol. 8 Núm. 9 (September 2013) , p. e74344  

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