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Correction : Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status: a study by ERIC in HARMONY
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Mansouri, Larry (Karolinska Institutet (Estocolm, Suècia)) ;
Thorvaldsdottir, Birna (Karolinska Institutet (Estocolm, Suècia). Department of Molecular Medicine and Surgery) ;
Sutton, Lesley-Ann (Karolinska Institutet (Estocolm, Suècia)) ;
Karakatsoulis, Georgios (University of Ioannina) ;
Meggendorfer, Manja (MLL Munich Leukemia Laboratory) ;
Parker, Helen (University of Southampton) ;
Nadeu, Ferran (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Brieghel, Christian (Copenhagen University Hospital) ;
Laidou, Stamatia (Institute of Applied Biosciences) ;
Moia, Riccardo (Università del Piemonte Orientale) ;
Rossi, Davide (Institute of Oncology Research) ;
Catherwood, Mark (Queen's University Belfast) ;
Kotaskova, Jana (Masaryk University) ;
Delgado, Julio (Hospital Clínic i Provincial de Barcelona) ;
Rodríguez-Vicente, Ana E. (Universidad de Salamanca) ;
Benito, Rocío (Universidad de Salamanca) ;
Rigolin, Gian Matteo (University of Ferrara) ;
Bonfiglio, Silvia (Università Vita Salute San Raffaele) ;
Scarfo, Lydia (Università Vita Salute San Raffaele) ;
Mattsson, Mattias (Uppsala University) ;
Davis, Zadie (University Hospitals Dorset) ;
Gogia, Ajay (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Rani, Lata (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Baliakas, Panagiotis (Uppsala University) ;
Foroughi-Asl, Hassan (Karolinska Institutet (Estocolm, Suècia)) ;
Jylhä, Cecilia (Karolinska Institutet (Estocolm, Suècia)) ;
Skaftason, Aron (Karolinska Institutet (Estocolm, Suècia)) ;
Rapado, Inmaculada (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ;
Miras, Fatima (Hospital Universitario 12 de Octubre (Madrid)) ;
Martinez-Lopez, Joaquín (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ;
de la Serna, Javier (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ;
Rivas, Jesús María Hernández (Universidad de Salamanca) ;
Thornton, Patrick (Beaumont Hospital (Dublín, Irlanda)) ;
Larráyoz, María José (Universidad de Navarra) ;
Calasanz, M.J (Universidad de Navarra) ;
Fésüs, Viktória (Semmelweis University) ;
Mátrai, Zoltán (Central Hospital of Southern Pest-National Institute of Hematology and Infectious Diseases (Budapest, Hongria)) ;
Bödör, Csaba (Semmelweis University) ;
Smedby, Karin E. (Karolinska Institutet (Estocolm, Suècia)) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Gupta, Ritu (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Bullinger, Lars (Charité - Universitätsmedizin Berlin) ;
Bosch José, Francesc Xavier 1947- (Vall d'Hebron Institut d'Oncologia) ;
Tazón-Vega, Bárbara (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Baran-Marszak, Fanny (Hôpital Avicenne AP-HP) ;
Oscier, David (University Hospitals Dorset) ;
Nguyen-Khac, Florence (Sorbonne University) ;
Zenz, Thorsten (University Hospital of Zurich) ;
Terol, Maria Jose (Universitat de València) ;
Cuneo, Antonio (University of Ferrara) ;
Hernández-Sánchez, María (Universidad de Salamanca) ;
Pospisilova, Sarka (Masaryk University) ;
Mills, Ken (Queen's University Belfast) ;
Gaidano, Gianluca (Università del Piemonte Orientale) ;
Niemann, Carsten U. (Copenhagen University Hospital) ;
Campo, Elias (Hospital Clínic i Provincial de Barcelona) ;
Strefford, Jonathan C. (University of Southampton) ;
Ghia, Paolo (Università Vita Salute San Raffaele) ;
Stamatopoulos, Kostas (Institute of Applied Biosciences) ;
Rosenquist, Richard (Karolinska University Hospital and Karolinska Institutet (Suècia))
2023 -  10.1038/s41375-023-01813-3
Leukemia, Vol. 37 (january 2023) , p. 504
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9 p, 1.7 MB |
Different prognostic impact of recurrent gene mutations in chronic lymphocytic leukemia depending on IGHV gene somatic hypermutation status : a study by ERIC in HARMONY
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Mansouri, Larry (Karolinska Institutet (Estocolm, Suècia)) ;
Thorvaldsdottir, Birna (Karolinska Institutet (Estocolm, Suècia)) ;
Sutton, Lesley-Ann (Karolinska Institutet (Estocolm, Suècia)) ;
Karakatsoulis, Georgios (University of Ioannina. Department of Mathematics) ;
Meggendorfer, Manja (MLL Munich Leukemia Laboratory) ;
Parker, Helen (University of Southampton) ;
Nadeu, Ferran (Centro de Investigación Biomédica en Red de Cáncer) ;
Brieghel, Christian (Copenhagen University Hospital. Department of Hematology, Rigshospitalet) ;
Laidou, Stamatia (Centre for Research and Technology Hellas (Tessalònica, Grècia)) ;
Moia, Riccardo (Università del Piemonte Orientale) ;
Rossi, Davide (Institute of Oncology Research (Suïssa)) ;
Catherwood, Mark (Queen's University Belfast) ;
Kotaskova, Jana (Masaryk University) ;
Delgado, Julio (Universitat de Barcelona) ;
Rodríguez-Vicente, Ana E. (Hospital Universitario de Salamanca) ;
Benito, Rocío (Hospital Universitario de Salamanca) ;
Rigolin, Gian Matteo (University of Ferrara) ;
Bonfiglio, Silvia (Università Vita Salute San Raffaele and IRCCS Ospedale San Raffaele) ;
Scarfo, Lydia (Università Vita Salute San Raffaele) ;
Mattsson, Mattias (Uppsala University. Department of Immunology, Genetics and Pathology) ;
Davis, Zadie (Molecular Pathology Department, University Hospitals Dorset) ;
Gogia, Ajay (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Rani, Lata (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Baliakas, Panagiotis (Uppsala University. Department of Immunology, Genetics and Pathology) ;
Foroughi-Asl, Hassan (Karolinska Institutet (Estocolm, Suècia)) ;
Jylhä, Cecilia (Karolinska Institutet (Estocolm, Suècia)) ;
Skaftason, Aron (Karolinska Institutet (Estocolm, Suècia)) ;
Rapado, Inmaculada (Spanish National Cancer Research) ;
Miras, Fatima (Hospital Universitario 12 de Octubre (Madrid)) ;
Martinez-Lopez, Joaquín (Spanish National Cancer Research) ;
de la Serna, Javier (Spanish National Cancer Research) ;
Rivas, Jesús María Hernández (Hospital Universitario de Salamanca) ;
Thornton, Patrick (Beaumont Hospital. Haematology Department) ;
Larráyoz, María José (Instituto de Investigación Sanitaria de Navarra) ;
Calasanz, M.J (Instituto de Investigación Sanitaria de Navarra) ;
Fésüs, Viktória (Semmelweis University) ;
Mátrai, Zoltán (Central Hospital of Southern Pest-National Institute of Hematology and Infectious Diseases, Budapest, Hungary) ;
Bödör, Csaba (Semmelweis University) ;
Smedby, Karin E. (Karolinska Institutet (Suècia). Department of Medicine Solna) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Gupta, Ritu (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Bullinger, Lars (Charité - Universitätsmedizin Berlin) ;
Bosch José, Francesc Xavier 1947- (Vall d'Hebron Institut d'Oncologia) ;
Tazón-Vega, Bárbara (Vall d'Hebron Institut d'Oncologia) ;
Baran-Marszak, Fanny (Service d'hématologie Biologique Hôpital Avicenne Assistance Publique des Hôpitaux de Paris) ;
Oscier, David (University Hospitals Dorset) ;
Nguyen-Khac, Florence (Sorbonne University) ;
Zenz, Thorsten (University Hospital and University of Zurich. Department of Oncology and Haematology) ;
Terol, Maria Jose (University of Valencia. Department of Hematology) ;
Cuneo, Antonio (University of Ferrara. Hematology-Department of Medical Sciences) ;
Hernández-Sánchez, María (Hospital Universitario de Salamanca) ;
Pospisilova, Sarka (Masaryk University. Central European Institute of Technology) ;
Mills, Ken (Queen's University Belfast) ;
Gaidano, Gianluca (Università del Piemonte Orientale) ;
Niemann, Carsten U. (Copenhagen University Hospital) ;
Campo, Elias (Universitat de Barcelona) ;
Strefford, Jonathan C. (University of Southampton) ;
Ghia, Paolo (Università Vita Salute San Raffaele and IRCCS Ospedale San Raffaele) ;
Stamatopoulos, Kostas (Institute of Applied Biosciences (Grècia)) ;
Rosenquist, Richard (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Universitat Autònoma de Barcelona
Recent evidence suggests that the prognostic impact of gene mutations in patients with chronic lymphocytic leukemia (CLL) may differ depending on the immunoglobulin heavy variable (IGHV) gene somatic hypermutation (SHM) status. [...]
2022 - 10.1038/s41375-022-01802-y
Leukemia, Vol. 37 (december 2022) , p. 339-347
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Karyotypic complexity rather than chromosome 8 abnormalities aggravates the outcome of chronic lymphocytic leukemia patients with TP53 aberrations
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Blanco, Gonzalo (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ;
Puiggros, Anna (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Baliakas, Panagiotis (Uppsala University. Department of Immunology, Genetics and Pathology) ;
Athanasiadou, Anastasia (G. Papanicolaou Hospital (Thessaloniki, Greece)) ;
García-Malo, MaDolores (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Collado, Rosa (Hospital General Universitario de Valencia) ;
Xochelli, Aliki (Institute of Applied Biosciences, CERTH, Thessaloniki, Greece) ;
Rodríguez-Rivera, María (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ortega, Margarita (Hospital Universitari Vall d'Hebron) ;
Calasanz, M.J (Universidad de Navarra. Departamento de Bioquímica y Genética) ;
Luño, Elisa (Hospital Universitario Central de Asturias) ;
Vargas, MªTeresa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Grau Cat, Javier (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Martínez-Laperche, Carolina (Hospital General Universitario Gregorio Marañón. Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM)) ;
Valiente, Alberto (Complejo Hospitalario de Navarra) ;
Cervera, José (Hospital Universitari i Politècnic La Fe (València)) ;
Anagnostopoulos, Achilles (George Papanicolaou General Hospital (Tessalònia, Grècia)) ;
Gimeno, Eva (Hospital del Mar (Barcelona, Catalunya)) ;
Abella Monreal, Eugenia (Hospital del Mar (Barcelona, Catalunya)) ;
Stalika, Evangelia (Institute of Applied Biosciences, CERTH, Thessaloniki, Greece) ;
Hernández Rivas, Jesús María (Hospital Universitario de Salamanca) ;
Ortuño, Francisco José (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Robles, Diego (Servicio de Hematología, Hospital Txagorritxu, Vitoria, Spain) ;
Ferrer, Ana (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Ivars, David (Hospital General Universitario de Valencia) ;
González, Marcos (Hospital Universitario de Salamanca. Centro de Investigación del Cáncer) ;
Bosch José, Francesc Xavier 1947- (Hospital Universitari Vall d'Hebron) ;
Abrisqueta, Pau (Hospital Universitari Vall d'Hebron) ;
Stamatopoulos, Kostas (Institute of Applied Biosciences, CERTH, Thessaloniki, Greece) ;
Espinet, Blanca (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Universitat Autònoma de Barcelona
Patients with chronic lymphocytic leukemia (CLL) harboring TP53 aberrations (TP53 abs; chromosome 17p deletion and/or TP53 mutation) exhibit an unfavorable clinical outcome. Chromosome 8 abnormalities, namely losses of 8p (8p−) and gains of 8q (8q+) have been suggested to aggravate the outcome of patients with TP53 abs. [...]
2016 - 10.18632/oncotarget.13106
Oncotarget, Vol. 7 (november 2016) , p. 80916-80924
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