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12 p, 4.1 MB NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism / Tu, Shichun (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Akhtar, Mohd Waseem (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Escorihuela, Rosa M (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Amador-Arjona, Alejandro (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Swarup, Vivek (University of California. Center for Autism Research and Treatment (CART)) ; Parker, James (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Zaremba, Jeffrey D. (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Holland, Timothy (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Bansal, Neha (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Holohan, Daniel R. (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Lopez, Kevin (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Ryan, Scott D. (Department of Molecular and Cellular Biology, University of Guelph, Guelph, Canada) ; Chan, Shing Fai (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Yan, Li (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Zhang, Xiaofei (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Huang, Xiayu (Sanford Burnham Prebys Medical Discovery Institute. Bioinformatics Core Facility) ; Sultan, Abdullah (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; McKercher, Scott R. (The Scripps Research Institute. Department of Molecular Medicine and Neuroscience, Neuroscience Translational Center) ; Ambasudhan, Rajesh (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Xu, Huaxi (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Wang, Yuqiang (Jinan University College of Pharmacy. Institute of New Drug Research) ; Geschwind, Daniel H. (University of California. Center for Autism Research and Treatment (CART)) ; Roberts, Amanda J. (The Scripps Research Institute. Department of Neuroscience and Mouse Behavioral Assessment Core) ; Terskikh, Alexey V. (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center) ; Rissman, Robert A. (Veterans Affairs San Diego Healthcare System) ; Masliah, Eliezer (Department of Neurosciences, University of California) ; Lipton, Stuart A. (University of California, San Diego, School of Medicine. Department of Neurosciences) ; Nakanishi, Nobuki (Sanford Burnham Prebys Medical Discovery Institute. Neuroscience and Aging Research Center)
Transcription factor MEF2C regulates multiple genes linked to autism spectrum disorder (ASD), and human MEF2C haploinsufficiency results in ASD, intellectual disability, and epilepsy. However, molecular mechanisms underlying MEF2C haploinsufficiency syndrome remain poorly understood. [...]
2017 - 10.1038/s41467-017-01563-8
Nature communications, Vol. 8 (november 2017)  
Detailed record - Creative Commons

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1 Bansal, Neha
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