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Articles, 2 records found
Articles 2 records found  
1.
14 p, 1.9 MB Impact of mutational studies on the diagnosis and the outcome of high-risk myelodysplastic syndromes and secondary acute myeloid leukemia patients treated with 5-azacytidine / Cabezón, Marta (Universitat Autònoma de Barcelona. Departament de Medicina) ; Bargay, Joan (Hospital Son Llàtzer, Mallorca) ; Xicoy, Blanca (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; García, Olga (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Borrás, Josep (Hospital Son Llàtzer, Mallorca) ; Tormo, Mar (Hospital Clínic de Valencia) ; Marcé, Sílvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pedro, Carme (Hospital del Mar, Barcelona) ; Valcárcel, David (Hospital Vall d'Hebron) ; Jiménez, Maria José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Guàrdia, Ramón (ICO Girona-Hospital Josep Trueta, Girona) ; Palomo, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Brunet, Salut (Institut d'Investigació Biomèdica Sant Pau) ; Vall-Llovera, Ferran (Hospital Mútua de Terrassa) ; Garcia, Antoni (Hospital Arnau de Vilanova, Lleida) ; Feliu, Evarist (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zamora, Lurdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Myelodysplastic syndromes (MDS) are stem cell disorders caused by various gene abnormalities. We performed targeted deep sequencing in 39 patients with high-risk MDS and secondary acute myeloid leukemia (sAML) at diagnosis and follow-up (response and/or relapse), with the aim to define their mutational status, to establish if specific mutations are biomarkers of response to 5-azacytidine (AZA) and/or may have impact on survival. [...]
2018 - 10.18632/oncotarget.25046
Oncotarget, Vol. 9 (april 2018) , p. 19342-19355  
2.
15 p, 1.7 MB The lincRNA HOTAIRM1, located in the HOXA genomic region, is expressed in acute myeloid leukemia, impacts prognosis in patients in the intermediate-risk cytogenetic category, and is associated with a distinctive microRNA signature / Díaz Beyá, Marina (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Brunet Mauri, Maria Salut (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Nomdedéu Guinot, Josep Francesc (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Pratcorona, Marta (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Cordeiro, Anna (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Gallardo, David (Institut Català d'Oncologia) ; Escoda, Lourdes (Hospital Joan XXIII (Tarragona)) ; Tormo, Mar (Hospital Clínico y Universitario de Valencia) ; Heras, Inmaculada (Hospital General Universitario Morales Meseguer (Múrcia)) ; Ribera Santasusana, J. M. (José María) (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Duarte, Rafael (Institut Català d'Oncologia) ; Llano Queipo, María Paz de (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ; Bargay, Joan (Hospital Son Llàtzer (Palma de Mallorca, Mallorca)) ; Sampol, Antonia (Hospital Son Espases (Palma de Mallorca, Mallorca)) ; Nomdedeu, Meritxell (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Risueño, Ruth M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Hoyos, Montserrat (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ; Sierra Gil, Jorge (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Monzo, Mariano (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Navarro, Alfons (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Esteve, Jordi (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Cooperative AML group CETLAM ; Universitat Autònoma de Barcelona
Long non-coding RNAs (lncRNAs) are deregulated in several tumors, although their role in acute myeloid leukemia (AML) is mostly unknown. We have examined the expression of the lncRNA HOX antisense intergenic RNA myeloid 1 (HOTAIRM1) in 241 AML patients. [...]
2015 - 10.18632/oncotarget.5148
Oncotarget, Vol. 6 Núm. 31 (October 2015)  

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1 Bargay, J
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