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Resultados globales: 3 registros encontrados en 0.02 segundos.
Artículos, Encontrados 3 registros
Artículos Encontrados 3 registros  
1.
14 p, 4.0 MB Graphene Oxide Nanoscale Platform Enhances the Anti-Cancer Properties of Bortezomib in Glioblastoma Models / Sharp, Paul S. (University of Manchester. Nanomedicine Lab) ; Stylianou, Maria (University of Manchester. Nanomedicine Lab) ; Arellano, Luis M. (Institut Català de Nanociència i Nanotecnologia) ; Neves, Juliana C. (Institut Català de Nanociència i Nanotecnologia) ; Gravagnuolo, Alfredo M. (University of Manchester. Nanomedicine Lab) ; Dodd, Abbie (University of Manchester. Nanomedicine Lab) ; Barr, Katharine (University of Manchester. Nanomedicine Lab) ; Lozano, Neus (Institut Català de Nanociència i Nanotecnologia) ; Kisby, Thomas (University of Manchester. Nanomedicine Lab) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
Graphene-based 2D nanomaterials possess unique physicochemical characteristics which can be utilized in various biomedical applications, including the transport and presentation of chemotherapeutic agents. [...]
2023 - 10.1002/adhm.202201968
Advanced Healthcare Materials, Vol. 12, Issue 3 (January 2023) , art. 2201968  
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2.
16 p, 4.4 MB Innate but not adaptive immunity regulates lung recovery from chronic exposure to graphene oxide nanosheets / Loret, Thomas (Manchester Academic Health Science Centre) ; De Luna, Luis Augusto Visani (Manchester Academic Health Science Centre) ; Fordham, Alexander (Manchester Academic Health Science Centre) ; Arshad, Atta (The University of Manchester. Nanomedicine Lab) ; Barr, Katharine (The University of Manchester. Nanomedicine Lab) ; Lozano, Neus (Institut Català de Nanociència i Nanotecnologia) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ; Bussy, Cyrill (Manchester Academic Health Science Centre)
Graphene has drawn a lot of interest in the material community due to unique physicochemical properties. Owing to a high surface area to volume ratio and free oxygen groups, the oxidized derivative, graphene oxide (GO) has promising potential as a drug delivery system. [...]
2022 - 10.1002/advs.202104559
Advanced science, Vol. 9, issue 11 (April 2022)  
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3.
15 p, 2.5 MB Deep tissue translocation of graphene oxide sheets in human glioblastoma 3D spheroids and an orthotopic xenograft model / de Lázaro, Irene (University of Manchester. Nanomedicine Lab) ; Sharp, Paul (University of Manchester. Nanomedicine Lab.) ; Gurcan, Cansu (Ankara University. Department of Biomedical Engineering) ; Ceylan, Ahmed (Ankara University. Faculty of Veterinary Medicine. Department of Histology Embryology) ; Stylianou, Maria (University of Manchester. Nanomedicine Lab.) ; Kisby, Thomas (University of Manchester. Nanomedicine Lab.) ; Chen, Yingxian (University of Manchester. Nanomedicine Lab.) ; Vranic, Sandra (University of Manchester. Nanomedicine Lab.) ; Barr, Katharine (University of Manchester. Nanomedicine Lab.) ; Taheri, Hadiseh (Ankara University. Department of Biomedical Engineering) ; Ozen, Asuman (Ankara University. Faculty of Veterinary Medicine. Department of Histology Embryology) ; Bussy, Cyrill (University of Manchester. Nanomedicine Lab.) ; Yilmazer, Acelya (Ankara University. Department of Biomedical Engineering) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
Its anatomical localization, a highly heterogeneous and drug-resistant tumor cell population and a "cold" immune microenvironment, all challenge the treatment of glioblastoma. Nanoscale drug delivery systems, including graphene oxide (GO) flakes, may circumvent some of these issues bypassing biological barriers, delivering multiple cargoes to impact several pathways simultaneously, or targeting the immune compartment. [...]
2021 - 10.1002/adtp.202000109
Advanced Therapeutics, Vol. 4, issue 1 (Jan. 2021) , art. 2000109  
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