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1.
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9 p, 1.1 MB |
Minimal disease activity (MDA) in patients with recent-onset psoriatic arthritis : predictive model based on machine learning
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Queiro, R. (Universidad de Oviedo) ;
Seoane-Mato, D. (Sociedad Española de Reumatología) ;
Laiz, Ana (Institut d'Investigació Biomèdica Sant Pau) ;
Agirregoikoa, E.G. (Hospital Universitario Basurto) ;
Montilla, C. (Hospital Universitario de Salamanca) ;
Park, Hye-Sang (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Pinto-Tasende, J.A. (Complejo Hospitalario Universitario de A Coruña) ;
Bethencourt Baute, Juan José (Hospital Universitario de Canarias (La Laguna) ;
Ibáñez, B.J. (Hospital Universitario 12 de Octubre) ;
Toniolo, E. (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Ramírez, Julio (Hospital Clínic i Provincial de Barcelona) ;
García, A.S. (Universidad Autónoma de Madrid) ;
Cañete, J. D. ;
Juanola, X. ;
Fiter, J. ;
Gratacós, J. ;
Rodriguez-Moreno, J. ;
Rosa, J.N. ;
Martín, A.L. ;
García, A.B. ;
Segura, P.C. ;
López-Ferrer, Anna (Institut d'Investigació Biomèdica Sant Pau) ;
Barrio, S.P. ;
Plata Izquierdo, A.J. ;
Bustabad, S. ;
Guimerá Martín-Neda, F.J. ;
Capdevilla, E.F. ;
Díaz, R.R. ;
Cuervo, A. ;
Gibert, M.A. ;
Larraz, P.T. ;
de la Morena Barrio, I. ;
Lanza, L.P. ;
Sanchís, D.B. ;
Mesquida, C.M. ;
Murillo, C. ;
Moreno Ramos, M.J. ;
Beteta, M.D. ;
Guillén, P.S.P. ;
Oliveira, L.L. ;
Marco, T.N. ;
Cebrián, L. ;
De la Cueva, Pablo ;
Steiner, M. ;
Muñoz-Fernández, S. ;
Garrido, R.V. ;
León, M. ;
Rubio, E. ;
Jiménez, A.M. ;
Fernández-Freire, L. R. ;
Luezas, J.M. ;
Sánchez-González, M.D. ;
Muñoz, C.S. ;
Senabre, J.M. ;
Rosas, J.C. ;
Soler, G.S. ;
Mataix Díaz, F.J. ;
Nieto-González, J.C. ;
González, C. ;
Ovalles Bonilla, J.G. ;
Rodríguez, O.B. ;
Medina, F.J.N. ;
Luján, D. ;
Ruiz Montesino, M.D. ;
Carrizosa Esquivel, A.M. ;
Fernández-Carballido, C. ;
Martínez-Vidal, M.P. ;
Fernández, L.G. ;
Jovani, V. ;
Alameda, R.C. ;
Sabater, S.G. ;
Romero, I.B. ;
Urruticoechea-Arana, A. ;
Torres, M.S. ;
Almodóvar, Raquel ;
López Estebaranz, J.L. ;
López Montilla, M.D. ;
García-Nieto, A.V. ;
Univetrsitat Autònoma de Barcelona
Very few data are available on predictors of minimal disease activity (MDA) in patients with recent-onset psoriatic arthritis (PsA). Such data are crucial, since the therapeutic measures used to change the adverse course of PsA are more likely to succeed if we intervene early. [...]
2022 -  10.1186/s13075-022-02838-2
Arthritis research & therapy, Vol. 24 Núm. 1 (december 2022) , p. 153
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2.
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7 p, 568.4 KB |
The more you take it, the better it works : Six-month results of a nalmefene phase-IV trial
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Barrio, Pablo (Hospital Clínic i Provincial de Barcelona) ;
Roncero, Carlos (Universidad de Salamanca) ;
Ortega, Lluisa (Hospital Clínic i Provincial de Barcelona) ;
Guardia, Josep (Institut d'Investigació Biomèdica Sant Pau) ;
Yuguero, Lara (Germanes Hospitalàries) ;
Gual, Antoni (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
Alcohol use disorders remain a major health problem. Reduced drinking has been increasingly recognized as a valuable alternative to abstinence. Nalmefene has shown in previous, experimental studies to be a useful tool to aid reduced drinking. [...]
2019 - 10.3390/jcm8040471
Journal of clinical medicine, Vol. 8 Núm. 4 (april 2019) , p. 471
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3.
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16 p, 657.0 KB |
Perspectives for systems biology in the management of tuberculosis
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Kontsevaya, Irina (University of Lübeck) ;
Lange, Christoph (University of Lübeck) ;
Comella-del-Barrio, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Coarfa, Cristian (Baylor College of Medicine) ;
DiNardo, Andrew R. (The Baylor College of Medicine) ;
Gillespie, Stephen H. (University of St Andrew) ;
Hauptmann, Matthias (Hamburg-Lübeck-Borstel-Riems) ;
Leschczyk, Christoph (Hamburg-Lübeck-Borstel-Riems) ;
Mandalakas, Anna M. (Baylor College of Medicine) ;
Martinecz, Antal (Arctic University of Norway) ;
Merker, Matthias (Hamburg-Lübeck-Borstel-Riems) ;
Niemann, Stefan (Hamburg-Lübeck-Borstel-Riems) ;
Reimann, Maja (University of Lübeck) ;
Rzhepishevska, Olena (Umeå University (Suècia)) ;
Schaible, Ulrich E. (Hamburg-Lübeck-Borstel-Riems) ;
Scheu, Katrin M. (Research Center Borstel) ;
Schurr, Erwin (Research Institute of the McGill University Health Centre (Montréal, Canada)) ;
Abel zur Wiesch, Pia (Pennsylvania State University (Estats Units d'Amèrica)) ;
Heyckendorf, Jan (University of Lübeck) ;
Universitat Autònoma de Barcelona
Standardised management of tuberculosis may soon be replaced by individualised, precision medicine-guided therapies informed with knowledge provided by the field of systems biology. Systems biology is a rapidly expanding field of computational and mathematical analysis and modelling of complex biological systems that can provide insights into mechanisms underlying tuberculosis, identify novel biomarkers, and help to optimise prevention, diagnosis and treatment of disease. [...]
2021 - 10.1183/16000617.0377-2020
European Respiratory Review, Vol. 30 (may 2021)
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4.
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12 p, 628.1 KB |
Obstetric outcomes of sars-cov-2 infection in asymptomatic pregnant women
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Cruz-Lemini, Monica (Institut d'Investigació Biomèdica Sant Pau) ;
Ferriols Pérez, Elena (Parc de Salut MAR de Barcelona) ;
De La Cruz Conty, Maria Luisa (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Caño Aguilar, Africa (Hospital Universitario San Cecilio (Granada)) ;
Encinas Pardilla, Maria Begoña (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Prats Rodriguez, Pilar (Hospital Universitari Dexeus (Barcelona, Catalunya)) ;
Mune Hernando, Marta (Hospital Universitario La Paz (Madrid)) ;
Forcen Acebal, Laura (Hospital Universitario 12 de Octubre (Madrid)) ;
Pintado Recarte, Pilar (Hospital General Universitario Gregorio Marañón) ;
Medina Mallen, Maria del Carmen (Institut d'Investigació Biomèdica Sant Pau) ;
Perez Perez, Noelia (Hospital Clínico San Carlos (Madrid)) ;
Canet Rodriguez, Judit (Hospital Santa Catarina) ;
Villazlba Yarza, Ana (Instituto de Investigación Biomédica de Salamanca) ;
Nieto Velasco, Olga (Grupo Quirónsalud (Madrid, Espanya)) ;
Del Barrio Fernandez, Pablo Guillermo (Hospital Universitario de Getafe (Madrid)) ;
Orizales Lago, Carmen Maria (Hospital Universitario Severo Ochoa) ;
Marcos Puig, Beatriz (Hospital Universitari i Politècnic La Fe (València)) ;
Muñoz Abellana, Begoña (Hospital Universitari Sant Joan de Reus (Tarragona)) ;
Fuentes Ricoy, Laura (Complejo Hospitalario Universitario de Ferrol) ;
Rodriguez Vicente, Agueda (Hospital Universitari de Girona Doctor Josep Trueta) ;
Janeiro Freire, Maria Jesus (Complejo Hospitalario Universitario de A Coruña) ;
Alferez Alvarez-Mallo, Macarena (HM Hospitals) ;
Casanova Pedraz, Cristina (Hospital Universitario de Torrejón) ;
Alomar Mateu, Onofre (Hospital Comarcal de Inca) ;
Lesmes Heredia, Cristina (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Wizner de Alva, Juan Carlos (Hospital San Pedro de Alcántara) ;
Posadas San Juan, Alma (Hospital Universitario Río Hortega (Valladolid)) ;
Macia Badia, Montserrat (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Alvarez Colomo, Cristina (Hospital Clínico Universitario de Valladolid) ;
Sanchez Muñoz, Antonio (Hospital General Universitario de Ciudad Real) ;
Pratcorona Alicart, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Alonso Saiz, Ruben (Hospital Universitario de Burgos) ;
Lopez Rodriguez, Monica (Hospital Universitari Joan XXIII de Tarragona) ;
Barbancho Lopez, Maria Carmen (Hospital Universitario Infanta Sofía (San Sebastián de los Reyes)) ;
Meca Casbas, Marta Ruth (Hospital Universitario Poniente) ;
Vaquerizo Ruiz, Oscar (Hospital Universitario Central de Asturias) ;
Moran Antolin, Eva (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Nuñez Valera, Maria Jose (Hospital Virgen de La Luz (Cuenca)) ;
fernandez Fernandez, Camino (Complejo Asistencial Universitario de León) ;
Tubau Navarra, Albert (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears)) ;
Cano Garcia, Alejandra Maria (Department of Gynecology and Obstetrics. University Hospital of El Tajo) ;
Soldevilla Perez, Susana (Hospital Universitario del Tajo) ;
Gattaca Abasolo, Irene (Arabako Unibertsitate Ospitalea (Vitoria, País Basc)) ;
Adanez Garcia, Jose (Hospital Universitario Central de Asturias) ;
Puertas Prieto, Alberto (Hospital Universitario Virgen de las Nieves (Granada)) ;
Ostos Serna, Rosa (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Guadix Martin, Maria del Pilar (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Catalina Coello, Monica (Hospital Virgen de la Concha (Zamora)) ;
Espuelas Malon, Silvia (Parc de Salut MAR de Barcelona) ;
Sainz Bueno, Jose Antonio (Hospital Viamed Santa Àngela de la Cruz) ;
Granell Escobar, Maria Reyes (Hospital Juan Ramón Jiménez (Huelva)) ;
Cruz Melguizo, Sara (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Martinez Perez, Oscar (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana)
Around two percent of asymptomatic women in labor test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Spain. Families and care providers face childbirth with uncertainty. [...]
2021 - 10.3390/v13010112
Viruses, Vol. 13 Núm. 1 (january 2021) , p. 112
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5.
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12 p, 995.8 KB |
Tobacco Smoking and Second-Hand Smoke Exposure Impact on Tuberculosis in Children
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Altet, Neus (Unitat Clínica de Tractament Directament Observat de la Tuberculosi (Barcelona)) ;
Latorre, Irene (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Jiménez-Fuentes, María Ángeles (Hospital Universitari Vall d'Hebron) ;
Soriano-Arandes, Antoni (Hospital Universitari Vall d'Hebron) ;
Villar-Hernández, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Milà, Celia (Hospital Universitari Vall d'Hebron) ;
Rodríguez-Fernández, Pablo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muriel-Moreno, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Comella-del-Barrio, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Godoy, Pere (Institut de Recerca Biomèdica de Lleida) ;
Millet, Joan-Pau (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
De Souza Galvão, Maria Luiza (Hospital Universitari Vall d'Hebron) ;
Jiménez-Ruiz, Carlos A. (Comunidad Autónoma de Madrid. Unidad de Tabaquismo) ;
Domínguez, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Little is known about whether second-hand smoke (SHS) exposure affects tuberculosis (TB). Here, we investigate the association of cigarette smoke exposure with active TB and latent TB infection (LTBI) in children, analyzing Interferon-Gamma Release Assays' (IGRAs) performance and cytokine immune responses. [...]
2022 - 10.3390/jcm11072000
Journal of clinical medicine, Vol. 11 (april 2022)
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6.
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11 p, 1.7 MB |
Urine NMR-based TB metabolic fingerprinting for the diagnosis of TB in children
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Comella-del-Barrio, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Izquierdo-Garcia, José Luis (Basque Research and Technology Alliance) ;
Gautier, Jacqueline (Hôpital Saint-Damien (Haití)) ;
Doresca, Mariette Jean Coute (Hôpital Saint-Damien (Haití)) ;
Campos-Olivas, Ramón (Centro Nacional de Investigaciones Oncológicas (Madrid)) ;
Santiveri, Clara M. (Centro Nacional de Investigaciones Oncológicas (Madrid)) ;
Muriel-Moreno, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prat i Aymerich, Cristina (University Medical Center Utrecht) ;
Abellana, Rosa (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut) ;
Pérez-Porcuna, Tomás M. (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Cuevas, Luis E.. (Liverpool School of Tropical Medicine. Department of Clinical Sciences) ;
Ruiz-Cabello, Jesús (IKERBASQUE, Basque Foundation for Science) ;
Domínguez, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Tuberculosis (TB) is a major cause of morbidity and mortality in children, and early diagnosis and treatment are crucial to reduce long-term morbidity and mortality. In this study, we explore whether urine nuclear magnetic resonance (NMR)-based metabolomics could be used to identify differences in the metabolic response of children with different diagnostic certainty of TB. [...]
2021 - 10.1038/s41598-021-91545-0
Scientific reports, Vol. 11 (june 2021)
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8 p, 268.4 KB |
Diagnostic Performance of the Fujifilm SILVAMP TB-LAM in Children with Presumptive Tuberculosis
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Comella-del-Barrio, Patricia (Institut Germans Trias i Pujol) ;
Molina-Moya, Barbara (Institut Germans Trias i Pujol) ;
Gautier, Jacqueline (Hôpital Saint-Damien) ;
Villar-Hernández, Raquel (Institut Germans Trias i Pujol) ;
Doresca, Mariette Jean Coute (Hôpital Saint-Damien) ;
Sallés-Mingels, Beatriz (Institut Català de la Salut) ;
Canales-Aliaga, Lydia (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Narcisse, Margareth (Department of Pediatrics, Division of Tuberculosis, Hôpital Saint-Damien, Nos Petits-Frères et Sœurs, Port-au-Prince 6112, Haiti; (J.G.); (M.J.C.D.); (M.N.)) ;
Pérez-Porcuna, Tomás M. (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Creswell, Jacob (Stop TB Partnership (Suïssa)) ;
Cuevas, Luis E.. (Liverpool School of Tropical Medicine) ;
Domínguez, José (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Current diagnostics for tuberculosis (TB) only manage to confirm a small proportion of children with TB and require respiratory samples, which are difficult to obtain. There is a need for non-invasive biomarker-based tests as an alternative to sputum testing. [...]
2021 - 10.3390/jcm10091914
Journal of clinical medicine, Vol. 10 (april 2021)
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8.
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13 p, 2.4 MB |
Discovery and validation of an NMR-based metabolomic profile in urine as TB biomarker
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Izquierdo-Garcia, José Luis (Universidad Complutense de Madrid) ;
Comella-del-Barrio, Patricia (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Campos-Olivas, Ramón (Centro Nacional de Investigaciones Oncológicas) ;
Villar-Hernández, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Prat i Aymerich, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
De Souza Galvão, Maria Luiza (Hospital Universitari Vall d'Hebron) ;
Jiménez-Fuentes, Maria Angeles (Hospital Universitari Vall d'Hebron) ;
Ruiz-Manzano, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Stojanovic, Zoran (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
González, Adela (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Serra-Vidal, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García-García, Esther (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muriel-Moreno, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Millet, Joan-Pau (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Molina-Pinargote, Israel (Unitat Clínica de Tractament Directament Observat de la Tuberculosi (Barcelona)) ;
Casas, Xavier (Unitat Clínica de Tractament Directament Observat de la Tuberculosi (Barcelona)) ;
Santiago, Javier (Unitat Clínica de Tractament Directament Observat de la Tuberculosi (Barcelona)) ;
Sabriá, Fina (Hospital de Sant Joan Despí Moisès Broggi) ;
Martos, Carmen (Hospital de Sant Joan Despí Moisès Broggi) ;
Herzmann, Christian (Research Center Borstel. Center for Clinical Studies, Germany) ;
Ruiz-Cabello, Jesús (IKERBASQUE, Basque Foundation for Science) ;
Domínguez, José (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Despite efforts to improve tuberculosis (TB) detection, limitations in access, quality and timeliness of diagnostic services in low- and middle-income countries are challenging for current TB diagnostics. [...]
2020 - 10.1038/s41598-020-78999-4
Scientific reports, Vol. 10 (december 2020)
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9.
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9 p, 376.9 KB |
Fujifilm silvamp tb-lam for the diagnosis of tuberculosis in nigerian adults
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Comella-del-Barrio, Patricia (Institut Germans Trias i Pujol) ;
Bimba, John (Bingham University. Zankli Research Centre and Department of Community Medicine) ;
Adelakun, Ramota (Liverpool School of Tropical Medicine. Department of Clinical Sciences) ;
Kontogianni, Konstantina (Liverpool School of Tropical Medicine. Department of Clinical Sciences) ;
Molina-Moya, Barbara (Institut Germans Trias i Pujol) ;
Osazuwa, Okoedoh (Bingham University. Zankli Research Centre and Department of Community Medicine) ;
Creswell, Jacob (TB REACH. Stop TB Partnership) ;
Cuevas, Luis E.. (Liverpool School of Tropical Medicine. Department of Clinical Sciences.) ;
Domínguez, José (Institut Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona.
Departament de Genètica i de Microbiologia
There is a need for diagnostics for tuberculosis (TB) that are easy to use, able to screen non-sputum samples, and able to provide rapid results for the management of both immunocompromised and immunocompetent individuals. [...]
2021 - 10.3390/jcm10112514
Journal of clinical medicine, Vol. 10 Núm. 11 (june 2021) , p. 2514
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10.
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11 p, 1.7 MB |
Effectiveness of a telephone-based intervention for smoking cessation in patients with severe mental disorders : Study protocol for a randomized controlled trial
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Ballbè, Montse (Hospital Clínic i Provincial de Barcelona) ;
Martínez, Cristina (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Feliu, Ariadna (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Torres, Núria (CatSalut Respon. Sistema d'Emergències Mèdiques. L'Hospitalet de Llobregat) ;
Nieva, Gemma (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pinet, Cristina (Institut d'Investigació Biomèdica Sant Pau) ;
Raich, Antònia (Althaia Xarxa Assistencial Universitària de Manresa) ;
Mondon, Sílvia (Hospital Clínic i Provincial de Barcelona) ;
Barrio, Pablo (Hospital Clínic i Provincial de Barcelona) ;
Hernández-Ribas, Rosa (Institut d'Investigació Biomèdica de Bellvitge) ;
Vicens, Jordi (Hospital Duran i Reynals (Hospitalet del Llobregat)) ;
Costa, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Vilaplana, Jordi (Institut de Recerca Biomèdica de Lleida) ;
Alaustre, Laura (CatSalut Respon. Sistema d'Emergències Mèdiques. L'Hospitalet de Llobregat) ;
Vilalta, Eva (CatSalut Respon. Sistema d'Emergències Mèdiques. L'Hospitalet de Llobregat) ;
Blanch, Roser (CatSalut Respon. Sistema d'Emergències Mèdiques. L'Hospitalet de Llobregat) ;
Subirà, Susana (Hospital Duran i Reynals (Hospitalet del Llobregat)) ;
Bruguera, Eugeni (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Suelves, Josep M (Servei Català de la Salut) ;
Guydish, Joseph (Philip R. Lee Institute for Health Policy Studies. University of California San Francisco) ;
Fernández, Esteve (Universitat de Barcelona. Departament de Ciències Clíniques) ;
Universitat Autònoma de Barcelona
Background: Up to 75% of inpatients with mental disorders smoke, and their life expectancy is decreased by up to 25 years compared to the general population. Hospitalized patients without monitoring after discharge quickly return to prehospitalization levels of tobacco use. [...]
2019 - 10.1186/s13063-018-3106-5
Trials, Vol. 20 Núm. 1 (november 2019) , p. 38
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