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1.
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0 p, 1.2 MB |
Cognitive Reserve as a Protective Factor of Mental Health in Middle-Aged Adults Affected by Chronic Pain
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Delgado-Gallén, Selma (Institut Germans Trias i Pujol. Institut Guttmann) ;
Soler, M. Dolors (Institut Germans Trias i Pujol. Institut Guttmann) ;
Albu, Sergiu (Institut Germans Trias i Pujol. Institut Guttmann) ;
Pachón-García, Catherine (Institut Germans Trias i Pujol. Institut Guttmann) ;
Alviarez-Schulze, Vanessa (Institut Germans Trias i Pujol. Institut Guttmann) ;
Solana-Sánchez, Javier (Institut Germans Trias i Pujol. Institut Guttmann) ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann) ;
Tormos, Jose M (Institut Germans Trias i Pujol. Institut Guttmann) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Chronic pain is associated with worse mental health and cognitive impairment, which can be a cause or a consequence of brain structure and function alterations, e. g. , maladaptive plasticity, antinociceptive system dysregulation. [...]
2021 -  10.3389/fpsyg.2021.752623
Frontiers in psychology, Vol. 12 (october 2021)
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2.
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10 p, 1.7 MB |
Diagnosis of prodromal and Alzheimer's disease dementia in adults with Down syndrome using neuropsychological tests
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Benejam, Bessy (Fundació Catalana Síndrome de Down) ;
Videla Toro, Laura (Institut d'Investigació Biomèdica Sant Pau) ;
Vilaplana, Eduard (Institut d'Investigació Biomèdica Sant Pau) ;
Barroeta, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Carmona Iragui, María (Institut d'Investigació Biomèdica Sant Pau) ;
Altuna-Azkargorta, Miren (Institut d'Investigació Biomèdica Sant Pau) ;
Valldeneu, Silvia (Institut d'Investigació Biomèdica Sant Pau) ;
Fernandez, S. (Fundació Catalana Síndrome de Down) ;
Giménez, Sandra (Institut d'Investigació Biomèdica Sant Pau) ;
Iulita, Florencia (Institut d'Investigació Biomèdica Sant Pau) ;
Garzón, Diana (Institut d'Investigació Biomèdica Sant Pau) ;
Bejanin, Alexandre (Institut d'Investigació Biomèdica Sant Pau) ;
Bartrés-Faz, David (Universitat de Barcelona) ;
Videla, S. (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas) ;
Alcolea, Daniel (Institut d'Investigació Biomèdica Sant Pau) ;
Blesa, Rafael (Institut d'Investigació Biomèdica Sant Pau) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Fortea, Juan (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
We aimed to define prodromal Alzheimer's disease (AD) and AD dementia using normative neuropsychological data in a large population-based cohort of adults with Down syndrome (DS). Cross-sectional study. [...]
2020 - 10.1002/dad2.12047
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring, Vol. 12 Núm. 1 (2020) , p. e12047
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3.
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9 p, 1.2 MB |
Prefrontal reactivity to TMS perturbation as a toy model of mental health outcomes during the COVID-19 pandemic
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Perellón Alfonso, Ruben (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Redondo-Camós, María (Institut Germans Trias i Pujol. Institut Guttmann) ;
Abellaneda‑Pérez, Kilian (Institut Germans Trias i Pujol. Institut Guttmann) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ;
Delgado Gallén, Selma (Institut Germans Trias i Pujol. Institut Guttmann) ;
España-Irla, Goretti (Institut Germans Trias i Pujol. Institut Guttmann) ;
Solana-Sánchez, Javier (Institut Germans Trias i Pujol. Institut Guttmann) ;
Tormos, Jose M (Institut Germans Trias i Pujol. Institut Guttmann) ;
Pascual Leone, Álvaro (Harvard Medical School) ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Psychosocial hardships associated with the COVID-19 pandemic led many individuals to suffer adverse mental health consequences, however, others show no negative effects. We hypothesized that the electroencephalographic (EEG) response to transcranial magnetic stimulation (TMS) could serve as a toy-model of an individual's capacity to resist psychological stress, in this case linked to the COVID-19 pandemic. [...]
2022 - 10.1016/j.heliyon.2022.e10208
Heliyon, Vol. 8 (august 2022)
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4.
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1 p, 149.4 KB |
Corrigendum to "Prefrontal reactivity to TMS perturbation as a toy model of mental health outcomes during the COVID-19 pandemic"[Heliyon 8 (8), (August 2022) Article e10208]
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Perellón-Alfonso, Ruben (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Redondo-Camós, María (Institut Germans Trias i Pujol) ;
Abellaneda‑Pérez, Kilian (Institut Germans Trias i Pujol. Institut Guttmann) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol) ;
Delgado-Gallén, Selma (Institut Germans Trias i Pujol) ;
España-Irla, Goretti (Institut Germans Trias i Pujol) ;
Solana-Sánchez, Javier (Institut Germans Trias i Pujol) ;
Tormos, José M. (Institut Germans Trias i Pujol) ;
Pascual Leone, Álvaro (Harvard Medical School) ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
2022 - 10.1016/j.heliyon.2022.e10758
Heliyon, Vol. 8 (september 2022) , p. e10758
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5.
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10 p, 933.0 KB |
Long-interval intracortical inhibition in primary motor cortex related to working memory in middle-aged adults
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Redondo-Camós, María (Institut Germans Trias i Pujol. Institut Guttmann) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ;
Alviarez-Schulze, Vanessa (Universitat de Barcelona) ;
Delgado-Gallén, Selma (Institut Germans Trias i Pujol. Institut Guttmann) ;
España-Irla, Goretti (Institut Germans Trias i Pujol. Institut Guttmann) ;
Solana-Sánchez, Javier (Institut Germans Trias i Pujol. Institut Guttmann) ;
Perellón-Alfonso, Ruben (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Albu, Sergiu (Institut Germans Trias i Pujol. Institut Guttmann) ;
Tormos, José M. (Institut Germans Trias i Pujol. Institut Guttmann) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Excitability of the primary motor cortex measured with TMS has been associated with cognitive dysfunctions in patient populations. However, only a few studies have explored this relationship in healthy adults, and even fewer have considered the role of biological sex. [...]
2022 - 10.3389/fpsyg.2022.998062
Frontiers in psychology, Vol. 13 (september 2022)
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6.
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11 p, 1012.8 KB |
Functional brain connectivity prior to the COVID-19 outbreak moderates the effects of coping and perceived stress on mental health changes. A first year of COVID-19 pandemic follow-up study
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Cabello-Toscano, María del Rocío (Institut Germans Trias i Pujol. Institut Guttmann) ;
Vaqué-Alcázar, Lídia (Institut de Recerca Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol) ;
Solana-Sánchez, Javier (Institut Germans Trias i Pujol) ;
Bayes-Marin, Ivet (Universitat de Barcelona) ;
Abellaneda‑Pérez, Kilian (Institut de Recerca Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain) ;
Macià Bros, Dídac (Department of Biomedicine, Faculty of Medicine and Health Sciences, Institute of Neurosciences, University of Barcelona, Barcelona, Spain) ;
Mulet Pons, Lídia (Institut de Recerca Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain) ;
Portellano-Ortiz, Cristina (Institut Germans Trias i Pujol. Institut Guttmann) ;
Fullana, Miquel Angel (Imaging of Mood- and Anxiety-Related Disorders (IMARD) Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), CIBERSAM, Barcelona, Spain) ;
Oleaga, Laura (Hospital Clínic i Provincial de Barcelona) ;
González, Sofía (Hospital Clínic i Provincial de Barcelona) ;
Bargalló, Núria (Hospital Clínic i Provincial de Barcelona) ;
Tormos, Jose M. (Institut Germans Trias i Pujol) ;
Pascual Leone, Álvaro (Department of Neurology, Harvard Medical School, Boston, MA, USA) ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann)
The COVID-19 pandemic provides a unique opportunity to investigate the psychological impact of a global major adverse situation. Our aim was to study, in a longitudinal prospective, the demographic, psychological and neurobiological factors associated with inter-individual differences in resilience to mental health pandemic impact. [...]
2022 - 10.1016/j.bpsc.2022.08.005
Biological Psychiatry. Cognitive Neuroscience and Neuroimaging, august 2022
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7.
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16 p, 1.6 MB |
Epigenome-Wide Association Study in Peripheral Tissues Highlights DNA Methylation Profiles Associated with Episodic Memory Performance in Humans
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Sommerer, Yasmine (University of Lübeck) ;
Dobricic, Valerija (University of Lübeck) ;
Schilling, Marcel (University of Lübeck) ;
Ohlei, Olena (University of Lübeck) ;
Bartrés-Faz, David (Campus Clínic August Pi i Sunyer) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ;
Demuth, Ilja (Charité - Universitätsmedizin Berlin) ;
Düzel, Sandra (Max Planck Institute for Human Development) ;
Franzenburg, Sören (Christian-Albrechts-University of Kiel) ;
Fuß, Janina (Christian-Albrechts-University of Kiel) ;
Lindenberger, Ulman (Max Planck Institute for Human Development) ;
Pascual Leone, Álvaro (Harvard Medical School) ;
Sabet, Sanaz Sedghpour (Christian-Albrechts-University of Kiel) ;
Solé-Padullés, Cristina (Campus Clínic August Pi i Sunyer) ;
Tormos, Josep M. (Institut Germans Trias i Pujol. Institut Guttmann) ;
Vetter, Valentin Max (Charité - Universitätsmedizin Berlin) ;
Wesse, Tanja (Christian-Albrechts-University of Kiel) ;
Franke, Andre (Christian-Albrechts-University of Kiel) ;
Lill, Christina M. (Imperial College London) ;
Bertram, Lars (University of Oslo) ;
Universitat Autònoma de Barcelona
The decline in episodic memory (EM) performance is a hallmark of cognitive aging and an early clinical sign in Alzheimer's disease (AD). In this study, we conducted an epigenome-wide association study (EWAS) using DNA methylation (DNAm) profiles from buccal and blood samples for cross-sectional (n = 1019) and longitudinal changes in EM performance (n = 626; average follow-up time 5. [...]
2022 - 10.3390/biomedicines10112798
Biomedicines, Vol. 10 (november 2022)
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8.
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13 p, 371.0 KB |
COVID-19 after two years : trajectories of different components of mental health in the Spanish population
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Bayes-Marin, Ivet (Universitat de Barcelona) ;
Cabello-Toscano, María del Rocío (Institut de Recerca Biomèdica August Pi i Sunyer) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ;
Solana-Sánchez, Javier (Institut Germans Trias i Pujol. Institut Guttmann) ;
Fernández, Daniel (BarcelonaTech (IMTech)) ;
Portellano-Ortiz, Cristina (Institut Germans Trias i Pujol. Institut Guttmann) ;
Tormos, Jose M (Institut Germans Trias i Pujol. Institut Guttmann) ;
Pascual Leone, Álvaro (Institut Germans Trias i Pujol. Institut Guttmann) ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann) ;
Universitat Autònoma de Barcelona
Our study aimed to (1) identify trajectories on different mental health components during a two-year follow-up of the COVID-19 pandemic and contextualise them according to pandemic periods; (2) investigate the associations between mental health trajectories and several exposures, and determine whether there were differences among the different mental health outcomes regarding these associations. [...]
2023 - 10.1017/S2045796023000136
Epidemiology and Psychiatric Sciences, Vol. 32 (april 2023)
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9.
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0 p, 841.5 KB |
The age-related contribution of cognitive function to dual-task gait in middle-aged adults in Spain : observations from a population-based study
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Zhou, Junhong ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ;
Yu, Wanting ;
Lo, On-Yee ;
Gouskova, Natalia A ;
Delgado-Gallén, Selma (Institut Germans Trias i Pujol. Institut Guttmann) ;
Redondo-Camós, María (Institut Germans Trias i Pujol. Institut Guttmann) ;
España-Irla, Goretti (Institut Germans Trias i Pujol. Institut Guttmann) ;
Solana-Sánchez, Javier (Institut Germans Trias i Pujol. Institut Guttmann) ;
Tormos, Josep M (Institut Germans Trias i Pujol. Institut Guttmann) ;
Lipsitz, Lewis A ;
Bartrés-Faz, David (Institut Germans Trias i Pujol. Institut Guttmann) ;
Pascual Leone, Álvaro ;
Manor, Brad ;
Universitat Autònoma de Barcelona
Poor dual-task gait performance is associated with a risk of falls and cognitive decline in adults aged 65 years or older. When and why dual-task gait performance begins to deteriorate is unknown. This study aimed to characterise the relationships between age, dual-task gait, and cognitive function in middle age (ie, aged 40-64 years). [...]
2023 - 10.1016/S2666-7568(23)00009-0
The lancet. Healthy longevity, Vol. 4 (march 2023) , p. e98-e106
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10.
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12 p, 1.6 MB |
Tele-supervised home-based transcranial alternating current stimulation (tACS) for Alzheimer's disease : a pilot study
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Cappon, Davide (Harvard Medical School) ;
Fox, Rachel (Deanna and Sidney Wolk Center for Memory Health at Hebrew SeniorLife) ;
den Boer, Tim (Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife) ;
Yu, Wanting (Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife) ;
LaGanke, Nicole (Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife) ;
Cattaneo, Gabriele (Institut Germans Trias i Pujol. Institut Guttmann) ;
Perellón-Alfonso, Ruben (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Bartrés-Faz, David (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Manor, Brad (Harvard Medical School) ;
Pascual Leone, Álvaro (Harvard Medical School) ;
Universitat Autònoma de Barcelona
Over 55 million people worldwide are currently diagnosed with Alzheimer's disease (AD) and live with debilitating episodic memory deficits. Current pharmacological treatments have limited efficacy. Recently, transcranial alternating current stimulation (tACS) has shown memory improvement in AD by normalizing high-frequency neuronal activity. [...]
2023 - 10.3389/fnhum.2023.1168673
Frontiers in human neuroscience, Vol. 17 (june 2023)
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