Resultats globals: 8 registres trobats en 0.02 segons.
Articles, 6 registres trobats
Documents de recerca, 2 registres trobats
Articles 6 registres trobats  
1.
12 p, 592.9 KB Glucocerebrosidase mRNA is Diminished in Brain of Lewy Body Diseases and Changes with Disease Progression in Blood / Perez-Roca, Laia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Adame Castillo, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Campdelacreu, Jaume (Hospital Universitari de Bellvitge) ; Ispierto, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vilas, Dolores (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rene, Ramon (Hospital Universitari de Bellvitge) ; Alvarez, Ramiro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gascon-Bayarri, Jordi (Hospital Universitari de Bellvitge) ; Serrano-Munoz, Maria A. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ariza Fernández, A (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Beyer, Katrin (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Parkinson disease (PD) and dementia with Lewy bodies (DLB) are Lewy body diseases characterized by abnormal alpha-synuclein deposits and overlapping pathological features in the brain. Several studies have shown that glucocerebrosidase (GBA) deficiency is involved in the development of LB diseases. [...]
2018 - 10.14336/AD.2017.0505
Aging and Disease, Vol. 9 (april 2018) , p. 208-219  
2.
15 p, 2.7 MB Expression Levels of an Alpha-Synuclein Transcript in Blood May Distinguish between Early Dementia with Lewy Bodies and Parkinson's Disease / Marsal-García, Laura (Institut Germans Trias i Pujol) ; Campdelacreu, Jaume (Hospital Universitari de Bellvitge) ; Vilas, Dolores (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ispierto, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gascón Bayarri, Jordi (Hospital Universitari de Bellvitge) ; Reñé, Ramón (Hospital Universitari de Bellvitge) ; Álvarez, Ramiro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Beyer, Katrin (Institut Germans Trias i Pujol) ; Urbizu, Aintzane (Institut Germans Trias i Pujol) ; Arnaldo, Laura (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Lewy body diseases (LBD) including dementia with Lewy bodies (DLB) and Parkinson disease (PD) are characterized by alpha-synuclein pathology. DLB is difficult to diagnose and peripheral biomarkers are urgently needed. [...]
2021 - 10.3390/ijms22020725
International journal of molecular sciences, Vol. 22 Núm. 2 (2021) , p. 725  
3.
17 p, 1.4 MB Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer's disease and dementia with Lewy bodies / Gámez-Valero, Ana (Institut Germans Trias i Pujol) ; Campdelacreu, Jaume (Hospital Universitari de Bellvitge) ; Vilas, Dolores (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ispierto, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Reñé, Ramón (Hospital Universitari de Bellvitge) ; Álvarez, Ramiro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Armengol, Maria del Pilar (Institut Germans Trias i Pujol) ; Borràs, Francesc E (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Beyer, Katrin (Institut Germans Trias i Pujol)
Because of the increasing life expectancy in our society, aging-related neurodegenerative disorders are one of the main issues in global health. Most of these diseases are characterized by the deposition of misfolded proteins and a progressive cognitive decline. [...]
2019 - 10.1186/s40035-019-0169-5
Translational Neurodegeneration, Vol. 8 (october 2019)  
4.
13 p, 3.2 MB Comprehensive proteomic profiling of plasma-derived Extracellular Vesicles from dementia with Lewy Bodies patients / Gámez-Valero, Ana (Institut Germans Trias i Pujol) ; Campdelacreu, Jaume (Hospital Universitari de Bellvitge) ; Reñé, Ramón (Hospital Universitari de Bellvitge) ; Beyer, Katrin (Institut Germans Trias i Pujol) ; Borràs, Francesc E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Proteins and nucleic acids contained in extracellular vesicles (EVs) are considered a feasible source of putative biomarkers for physiological and pathological conditions. Within the nervous system, not only neurons but also other brain cells are able to produce EVs, which have been involved in their physiological processes and also in the development and course of several neurodegenerative diseases. [...]
2019 - 10.1038/s41598-019-49668-y
Scientific reports (Nature Publishing Group), Vol. 9 (September 2019) , art. 13282  
5.
9 p, 1.4 MB Size-Exclusion Chromatography-based isolation minimally alters Extracellular Vesicles' characteristics compared to precipitating agents / Gámez Valero, Ana (Institut Germans Trias i Pujol) ; Monguió Tortajada, Marta (Institut Germans Trias i Pujol) ; Carreras Planella, Laura (Institut Germans Trias i Pujol) ; Franquesa, Marcel·la (Institut Germans Trias i Pujol) ; Beyer, Katrin (Institut Germans Trias i Pujol) ; Borràs, Francesc E (Institut Germans Trias i Pujol)
Extracellular vesicles (EVs) have become an attractive field among the scientific community. Yet, a major challenge is to define a consensus method for EVs isolation. Ultracentrifugation has been the most widely used methodology but rapid methods, including Size Exclusion Chromatography (SEC) and/or precipitating agents such as Polyethylene glycol (PEG) or PRotein Organic Solvent PRecipitation (PROSPR) have emerged. [...]
2016 - 10.1038/srep33641
Scientific reports (Nature Publishing Group), Vol. 6 (September 2016)  
6.
22 p, 99.8 KB Molecular Pathology of Lewy Body Diseases / Beyer, Katrin (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Domingo-Sàbat, Montse (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ariza Fernández, A. (Aurelio) (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques)
Lewy body diseases are characterized by the presence of Lewy bodies, alphasynuclein(AS)-positive inclusions in the brain. Since their main component is conformationally modified AS, aggregation of the latter is thought to be a key pathogenic event in these diseases. [...]
2009 - 10.3390/ijms10030724
International journal of molecular sciences, Vol. 10 (2009) , p. 724-745  

Documents de recerca 2 registres trobats  
1.
174 p, 3.4 MB Genètica de la Butirilcolinesterasa en les sinucleïnopaties: Establiment d'una eina pel diagnòstic diferencial de la demència amb cossos de Lewy / Domingo-Sàbat, Montse ; Beyer, Katrin, dir. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Casas Louzao, Caty, tut. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular i de Fisiologia
Les malalties neurodegeneratives es desenvolupen gràcies a diferents mecanismes moleculars, que produeixen agregació de proteïnes mal plegades en diverses àrees cerebrals. D'una banda, l'α-sinucleïna es troba als cossos de Lewy presents a la malaltia de Parkinson i a les demències amb cossos de Lewy (DCL: DCL de tipus pur, DCLp; DCL de tipus comuna, DCLc) i a les inclusions citoplasmàtiques glials, que són la característica neuropatològica de l'atròfia multisistèmica (AMS). [...]
Neurodegenerative diseases develop through different molecular mechanisms that produce aggregation of unfolded proteins in different brain areas. On one hand, α-synuclein is present in Lewy bodies that can be found in Parkinson's disease and in dementia with Lewy bodies (DLB: pure DLB, pDLB; common DLB, cDLB) and in glial cytoplasmic inclusions (GCI) that are the pathological hallmark of multiple system atrophy (MSA). [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2011  
2.
175 p, 1.2 MB Caracterización genética de la enfermedad de Alzheimer : : estudio poblacional / Beyer, Katrin ; Ariza Fernández, A., (Aurelio), dir. (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques)
Vegeu tesi doctoral.
Bellaterra : Universitat Autònoma de Barcelona, 2005  

Vegeu també: autors amb noms similars
1 Beyer, K.
1 Beyer, Katrin,
2 Beyer, Kirsten
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