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Artículos, Encontrados 8 registros
Artículos Encontrados 8 registros  
1.
Intracerebral injection of graphene oxide nanosheets mitigates microglial activation without inducing aAcute neurotoxicity : a pilot comparison to other nanomaterials / Portioli, Corinne (University of Verona. Department of Neurosciences, Biomedicine and Movement Sciences) ; Bussy, Cyrill (Lydia Becker Institute of Immunology and Inflammation) ; Mazza, Mariarosa (The University of Manchester. Nanomedicine Lab.) ; Lozano, Neus (Institut Català de Nanociència i Nanotecnologia) ; Jasim, Dhifaf A. (The University of Manchester. Nanomedicine Lab.) ; Prato, Maurizio (Ikerbasque) ; Bianco, Alberto (CNRS. University of Strasbourg. Immunology, Immunopathology and Therapeutic Chemistry) ; Bentivoglio, Marina (University of Verona. Department of Neurosciences, Biomedicine and Movement Sciences) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia)
Carbon-based nanomaterials (CNMs) are being explored for neurological applications. However, systematic in vivo studies investigating the effects of CNM nanocarriers in the brain and how brain cells respond to such nanomaterials are scarce. [...]
2020 - 10.1002/smll.202004029
Small, Vol. 16, issue 48 (Dec. 2020) , art. 2004029  
2.
17 p, 13.0 MB Size-dependent pulmonary impact of thin graphene oxide sheets in mice : toward safe-by-design / Rodrigues, Artur Filipe (University of Manchester. Nanomedicine Lab) ; Newman, Leon (University of Manchester. Nanomedicine Lab) ; Jasim, Dhifaf (University of Manchester. Nanomedicine Lab) ; Mukherjee, Sourav P. (Karolinska Institutet. Nanosafety & Nanomedicine Laboratory) ; Wang, Jun (Stockholm University. Department of Biochemistry and Biophysics) ; Vacchi, Isabella A. (Centre National de la Recherche Scientifique. University of Strasbourg. Immunology, Immunopathology and Therapeutic Chemistry) ; Ménard-Moyon, Cécilia (Centre National de la Recherche Scientifique. University of Strasbourg. Immunology, Immunopathology and Therapeutic Chemistry) ; Bianco, Alberto (Centre National de la Recherche Scientifique. University of Strasbourg. Immunology, Immunopathology and Therapeutic Chemistry) ; Fadeel, Bengt (Karolinska Institutet. Nanosafety & Nanomedicine Laboratory) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ; Bussy, Cyrill (Lydia Becker Institute of Immunology and Inflammation)
Safety assessment of graphene-based materials (GBMs) including graphene oxide (GO) is essential for their safe use across many sectors of society. In particular, the link between specific material properties and biological effects needs to be further elucidated. [...]
2020 - 10.1002/advs.201903200
Advanced science, Vol. 7, issue 12 (june 2020) , art. 1903200  
3.
40 p, 2.2 MB Covalent functionalization of multi-walled carbon nanotubes with a gadolinium chelate for efficient T1-weighted magnetic resonance imaging / Marangon, Iris (Université de Paris VII. Laboratoire Matières et Systèmes Complexes) ; Ménard-Moyon, Cécilia (Centre national de la recherche scientifique (France)) ; Kolosnjaj-Tabi, Jelena (Université de Paris VII. Laboratoire Matières et Systèmes Complexes) ; Béoutis, Marie Lys (Université de Paris VII. Laboratoire Matières et Systèmes Complexes) ; Lartigue, Lénaic (Université de Paris VII. Laboratoire Matières et Systèmes Complexes) ; Alloyeau, Damien (Université de Paris VII. Laboratoire Matériaux et Phénomènes Quantiques) ; Pach, Elzbieta (Institut Català de Nanociència i Nanotecnologia) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Autret, Gwennhael (Université de Paris V) ; Ninjbadgar, Tsedev (Shine Mongol Institute of Technology. Faculty of Engineering) ; Brougham, Dermot F. (Dublin City University. School of Chemical Sciences) ; Bianco, Alberto (Centre national de la recherche scientifique. Laboratoire d'Immunopathologie et Chimie Thérapeutique) ; Gazeau, Florence (Université de Paris VII. Laboratoire Matières et Systèmes Complexes)
Given the promise of carbon nanotubes (CNTs) for photothermal therapy, drug delivery, tissue engineering, and gene therapy, there is a need for non-invasive imaging methods to monitor CNT distribution and fate in the body. [...]
2014 - 10.1002/adfm.201402234
Advanced functional materials, Vol. 24, issue 45 (Dec. 2014) , p. 7173-7186  
4.
Neutron-irradiated antibody-functionalised carbon nanocapsules for targeted cancer radiotherapy / Wang, Julie T. W. (King's College London. Institute of Pharmaceutical Science) ; Spinato, Cinzia (Université de Strasbourg. Centre national de la recherche scientifique) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Costa, Pedro M. (King's College London. Institute of Pharmaceutical Science) ; Martincic, Markus (Institut de Ciència de Materials de Barcelona) ; Pach, Elzbieta (Institut Català de Nanociència i Nanotecnologia) ; Pérez Ruiz De Garibay, Aritz (Université de Strasbourg. Centre national de la recherche scientifique) ; Ménard-Moyon, Cécilia (Université de Strasbourg. Centre national de la recherche scientifique) ; Feldman, Robert (Cis Bio International Ion Beam Applications SA) ; Michel, Yves (Cis Bio International Ion Beam Applications SA) ; Šefl, Martin (University of Ioannina Medical School) ; Kyriakou, Ioanna (University of Ioannina Medical School) ; Emfietzoglou, Dimitris (University of Ioannina Medical School) ; Saccavini, Jean-Claude (Cis Bio International Ion Beam Applications SA) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Tobias, Gerard (Institut de Ciència de Materials de Barcelona) ; Bianco, Alberto (Université de Strasbourg. Centre national de la recherche scientifique) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science)
Radiotherapy is a cancer treatment utilising high doses of ionizing radiation to destroy cancer cells. Our team has pioneered neutron activation of Sm, filled and sealed into single-walled (SWCNTs) and multi-walled carbon nanotubes (MWCNTs), to create stable and high-dose radioactive carbon nanocapsules for cancer radiotherapy. [...]
2020 - 10.1016/j.carbon.2020.02.060
Carbon, Vol. 162 (June 2020) , p. 410-422  
5.
59 p, 2.2 MB Neutron Activated 153Sm Sealed in Carbon Nanocapsules for in Vivo Imaging and Tumor Radiotherapy / Wang, Julie T. W. (King's College London. Institute of Pharmaceutical Science) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Martincic, Markus (Institut de Ciència de Materials de Barcelona) ; Pach, Elzbieta (Institut Català de Nanociència i Nanotecnologia) ; Feldman, Robert (Cis Bio International Ion Beam Applications SA) ; Šefl, Martin (Czech Technical University in Prague) ; Michel, Yves (Cis Bio International Ion Beam Applications SA) ; Asker, Daniel (King's College London. Institute of Pharmaceutical Science) ; Sosabowski, Jane K. (Queen Mary University of London) ; Kalbáč, Martin (J. Heyrovsky Institute of the Physical Chemistry) ; Da Ros, Tatiana (University of Trieste. Department of Chemical and Pharmaceutical Sciences) ; Ménard-Moyon, Cécilia (Université de Strasbourg. Centre national de la recherche scientifique) ; Bianco, Alberto (Université de Strasbourg. Centre national de la recherche scientifique) ; Kyriakou, Ioanna (University of Ioannina Medical School) ; Emfietzoglou, Dimitris (University of Ioannina Medical School) ; Saccavini, Jean-Claude (Cis Bio International Ion Beam Applications SA) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science) ; Tobias, Gerard (Institut de Ciència de Materials de Barcelona)
Radiation therapy along with chemotherapy and surgery remain the main cancer treatments. Radiotherapy can be applied to patients externally (external beam radiotherapy) or internally (brachytherapy and radioisotope therapy). [...]
2020 - 10.1021/acsnano.9b04898
ACS nano, Vol. 14, Issue 1 (January 2020) , p. 129-141  
6.
12 p, 1.4 MB Evaluation of the immunological profile of antibody-functionalized metal-filled single-walled carbon nanocapsules for targeted radiotherapy / Perez Ruiz De Garibay, Aritz (Université de Strasbourg. Centre national de la recherche scientifique) ; Spinato, Cinzia (Université de Strasbourg. Centre national de la recherche scientifique) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Bourgognon, Maxime (King's College London. Institute of Pharmaceutical Science) ; Martincic, Markus (Institut de Ciència de Materials de Barcelona) ; Pach, Elzbieta (Institut Català de Nanociència i Nanotecnologia) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Ménard-Moyon, Cécilia (Université de Strasbourg. Centre national de la recherche scientifique) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science) ; Tobias, Gerard (Institut de Ciència de Materials de Barcelona) ; Bianco, Alberto (Université de Strasbourg. Centre national de la recherche scientifique)
This study investigates the immune responses induced by metal-filled single-walled carbon nanotubes (SWCNT) under in vitro, ex vivo and in vivo settings. Either empty amino-functionalized CNTs [SWCNT-NH 2 (1)] or samarium chloride-filled amino-functionalized CNTs with [SmCl 3 @SWCNT-mAb (3)] or without [SmCl 3 @SWCNT-NH 2 (2)] Cetuximab functionalization were tested. [...]
2017 - 10.1038/srep42605
Scientific reports (Nature Publishing Group), Vol. 7 (February 2017) , art. 42605  
7.
19 p, 868.7 KB Design of antibody-functionalized carbon nanotubes filled with radioactivable metals towards a targeted anticancer therapy / Spinato, Cinzia (Centre national de la recherche scientifique (França). Institut de Biologie Moléculaire et Cellulaire. Laboratoire d'Immunopathologie et Chimie Thérapeutique) ; Perez Ruiz De Garibay, Aritz (Centre national de la recherche scientifique (França). Institut de Biologie Moléculaire et Cellulaire. Laboratoire d'Immunopathologie et Chimie Thérapeutique) ; Kierkowicz, Magdalena (Institut de Ciència de Materials de Barcelona) ; Pach, Elzbieta (Institut Català de Nanociència i Nanotecnologia) ; Martincic, Markus (Institut de Ciència de Materials de Barcelona) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Bourgognon, Maxime (King's College London. Institute of Pharmaceutical Science) ; Wang, Julie Tzu-Wen (King's College London. Institute of Pharmaceutical Science) ; Ménard-Moyon, Cécilia (Centre national de la recherche scientifique (França). Institut de Biologie Moléculaire et Cellulaire. Laboratoire d'Immunopathologie et Chimie Thérapeutique) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Tobias, Gerard (Institut de Ciència de Materials de Barcelona) ; Bianco, Alberto (Centre national de la recherche scientifique (França). Institut de Biologie Moléculaire et Cellulaire. Laboratoire d'Immunopathologie et Chimie Thérapeutique)
In the present work we have devised the synthesis of a novel promising carbon nanotube carrier for the targeted delivery of radioactivity, through a combination of endohedral and exohedral functionalization. [...]
2016 - 10.1039/c5nr07923c
Nanoscale, Vol. 8, issue 25 (2016) , p. 12626-12638  
8.
214 p, 55.9 MB Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems / Ferrari, Andrea C. (University of Cambridge) ; Bonaccorso, Francesco (Istituto Italiano di Tecnologia) ; Fal'ko, Vladimir (Lancaster University. Department of Physics) ; Novoselov, Konstantin S. (University of Manchester) ; Roche, Stephan (Institut Català de Nanociència i Nanotecnologia) ; Bøggild, Peter (Technical University of Denmark) ; Borini, Stefano (Nokia Technologies) ; Koppens, Frank H.L. (Institut de Ciències Fotòniques) ; Palermo, Vincenzo (CNR-Istituto per la Sintesi Organica e la Fotoreattività) ; Pugno, Nicola (Queen Mary University of London) ; Garrido, Jose (Technische Universität München) ; Sordan, Roman (Politecnico di Milano) ; Bianco, Alberto (Institut de Biologie Moleculaire et Cellulaire) ; Ballerini, Laura (Università di Trieste) ; Prato, Maurizio (Università di Trieste. Dipartimento di Scienze Farmaceutiche) ; Lidorikis, Elefterios (University of Ioannina. Department of Materials Science and Engineering) ; Kivioja, Jani (Nokia Technologies) ; Marinelli, Claudio (Wilton Centre) ; Ryhänen, Tapani (Nokia Technologies) ; Morpurgo, Alberto (Université de Genève. Département de Physique de la Matière Condensée) ; Coleman, Jonathan N. (Trinity College) ; Nicolosi, Valeria (Trinity College) ; Colombo, Luigi (Texas Instruments Incorporated) ; Fert, Albert (Université de Paris-Sud) ; García Hernández, Mar (Instituto de Ciencia de Materiales de Madrid) ; Bachtold, Adrian (Institut de Ciències Fotòniques) ; Schneider, Gregory F. (Leiden University) ; Guinea, Francisco (Instituto de Ciencia de Materiales de Madrid) ; Dekker, Cees (Delft University of Technology) ; Barbone, Matteo (University of Cambridge) ; Sun, Zhipei (University of Cambridge) ; Galiotis, Costas (University of Patras. Department of Chemical Engineering) ; Grigorenko, Alexander N. (University of Manchester) ; Konstantatos, Gerasimos (Institut de Ciències Fotòniques) ; Kis, Andras (Ecole Polytechique Fédérale de Lausanne) ; Katsnelson, Mikhail (Radboud University Nijmegen) ; Vandersypen, Lieven (Delft University of Technology) ; Loiseau, Annick (Laboratoire d'Etude des Microstructures) ; Morandi, Vittorio (CNR-Istituto per la Microelettronica e i Microsistemi) ; Neumaier, Daniel (Advanced Microelectronic Centre Aachen) ; Treossi, Emanuele (CNR-Istituto per la Sintesi Organica e la Fotoreattività) ; Pellegrini, Vittorio (Scuola Normale Superiore) ; Polini, Marco (Scuola Normale Superiore) ; Tredicucci, Alessandro (Scuola Normale Superiore) ; Williams, Gareth M. (Airbus UK Ltd) ; Hee Hong, Byung (Seoul National University. Department of Chemistry) ; Ahn, Jong Hyun (Yonsei University) ; Kim, Jong Min (University of Oxford. Department of Engineering Science) ; Zirath, Herbert (Chalmers University of Technology. Department of Microtechnology and Nanoscience) ; Van Wees, Bart J. (University of Groningen) ; Van Der Zant, Herre S.J. (Delft University of Technology) ; Occhipinti, Luigi (STMicroelectronics) ; Di Matteo, Andrea (STMicroelectronics) ; Kinloch, Ian A. (University of Manchester) ; Seyller, Thomas (Technische Universität Chemnitz) ; Quesnel, Etienne (Institut LITEN) ; Feng, Xinliang (Max-Planck-Institut für Polymerforschung) ; Teo, Ken (Aixtron Ltd.) ; Rupesinghe, Nalin (Aixtron Ltd.) ; Hakonen, Pertti (Aalto University) ; Neil, Simon R.T. (CambridgeIP) ; Tannock, Quentin (CambridgeIP) ; Löfwander, Tomas (Chalmers University of Technology. Department of Microtechnology and Nanoscience) ; Kinaret, Jari (Chalmers University of Technology. Department of Applied Physics)
We present the science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems, targeting an evolution in technology, that might lead to impacts and benefits reaching into most areas of society. [...]
2015 - 10.1039/c4nr01600a
Nanoscale, Vol. 7, Issue 11 (March 2015) , p. 4598-4810  

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