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1.
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9 p, 1.1 MB |
Plasma phosphorylated tau 181 predicts amyloid status and conversion to dementia stage dependent on renal function
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Lehmann, Sylvain (IRMB CHU de Montpellier) ;
Schraen-Maschke, Susanna (CHU Lille) ;
Vidal, Jean-Sébastien (APHP) ;
Delaby, Constance (Institut d'Investigació Biomèdica Sant Pau) ;
Blanc, Frédéric (University Hospital of Strasbourg) ;
Paquet, Claire (Centre de Neurologie Cognitive) ;
Allinquant, Bernadette (Inserm) ;
Bombois, Stéphanie (GH Pitié-Salpêtrière) ;
Gabelle, Audrey (Inserm INM) ;
Hanon, Olivier (APHP) ;
Universitat Autònoma de Barcelona
Plasma P-tau181 is an increasingly established diagnostic marker for Alzheimer's disease (AD). Further validation in prospective cohorts is still needed, as well as the study of confounding factors that could influence its blood level. [...]
2023 -  10.1136/jnnp-2022-330540
Journal of Neurology, Neurosurgery, and Psychiatry, Vol. 94 (april 2023) , p. 411-419
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2 p, 695.4 KB |
Author Correction : GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
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Rongve, Arvid (The University of Bergen) ;
Witoelar, Aree (University of Oslo. Institute of Clinical Medicine) ;
Ruiz, Agustín (Fundació ACE) ;
Athanasiu, Lavinia (University of Oslo) ;
Abdelnour, Carla (Fundació ACE) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Heilmann-Heimbach, Stefanie (University of Bonn) ;
Hernández, Isabel (Fundació ACE) ;
Moreno-Grau, Sonia (Fundació ACE) ;
De Rojas, Itziar (Fundació ACE) ;
Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ;
Fladby, Tormod (University of Oslo) ;
Sando, Sigrid B. (Norwegian University of Science and Technology) ;
Bråthen, Geir (St Olav's University Hospital) ;
Blanc, Frédéric (University of Strasbourg) ;
Bousiges, Olivier (University Hospital of Strasbourg) ;
Lemstra, Afina W. (Amsterdam UMC. University Medical Center) ;
van Steenoven, Inger (Amsterdam UMC. University Medical Center) ;
Londos, Elisabet (Skåne University Hospital (Suècia)) ;
Almdahl, Ina S. (Oslo University Hospital (Oslo, Noruega)) ;
Pålhaugen, Lene (University of Oslo) ;
Eriksen, Jon A. (University of Oslo) ;
Djurovic, Srdjan (University of Bergen) ;
Stordal, Eystein (Norwegian University of Science and Technology) ;
Saltvedt, Ingvild (St Olav's University Hospital) ;
Ulstein, Ingun D. (Oslo University Hospital (Oslo, Noruega)) ;
Bettella, Francesco (Oslo University Hospital (Oslo, Noruega)) ;
Desikan, Rahul S. (Neurology and Pediatrics, UCSF.) ;
Idland, Ane-Victoria (University of Oslo. Institute of Basic Medical Sciences) ;
Toft, Mathias (Oslo University Hospital (Oslo, Noruega)) ;
Pihlstrøm, Lasse (Oslo University Hospital (Oslo, Noruega)) ;
Snaedal, Jon (Landspitali University Hospital (Reykjavík, Islàndia)) ;
Tárraga, Lluís (Fundació ACE) ;
Boada, Mercè (Fundació ACE) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Stefánsson, Hreinn (deCODE Genetics (Reykjavík, Islàndia)) ;
Stefánsson, Kári (deCODE Genetics (Reykjavík, Islàndia)) ;
Ramirez, Alfredo (University of Bonn) ;
Aarsland, Dag (Stavanger University Hospital) ;
Andreassen, Ole A. (University of Oslo) ;
Universitat Autònoma de Barcelona
2019 - 10.1038/s41598-019-51827-0
Scientific reports, Vol. 9 (october 2019)
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13 p, 1.5 MB |
Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data
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Abdelnour, Carla (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ferreira, Daniel (Karolinska Institutet (Estocolm, Suècia)) ;
van de Beek, Marleen (Vrije Universiteit Amsterdam) ;
Cedres, Nira (Stockholm University) ;
Oppedal, Ketil (University of Stavanger) ;
Cavallin, Lena (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Blanc, Frédéric (Centre Mémoire, de Ressources et de Recherche d'Alsace (Strasbourg-Colmar)) ;
Bousiges, Olivier (University Hospital of Strasbourg) ;
Wahlund, Lars-Olof (Karolinska Institutet (Estocolm, Suècia)) ;
Pilotto, Andrea (University of Brescia) ;
Padovani, Alessandro (University of Brescia) ;
Boada, Mercè (Universitat Internacional de Catalunya) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Aarsland, Dag (King's College London) ;
Lemstra, Afina W. (Vrije Universiteit Amsterdam) ;
Westman, Eric (King's College London)
Dementia with Lewy bodies (DLB) includes various core clinical features that result in different phenotypes. In addition, Alzheimer's disease (AD) and cerebrovascular pathologies are common in DLB. All this increases the heterogeneity within DLB and hampers clinical diagnosis. [...]
2022 - 10.1186/s13195-021-00946-w
Alzheimer's research & therapy, Vol. 14 (january 2022)
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4.
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9 p, 763.7 KB |
The combined effect of amyloid-β and tau biomarkers on brain atrophy in dementia with Lewy bodies
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Abdelnour, Carla (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Ferreira, Daniel (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ;
Oppedal, Ketil (Department of Electrical Engineering and Computer Science, University of Stavanger, Stavanger, Norway) ;
Cavallin, Lena (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Bousiges, Olivier (Hôpitaux Universitaire de Strasbourg, Laboratoire de Biochimie et Biologie Moléculaire, et CNRS, Laboratoire de Neurosciences Cognitives et Adaptatives (LNCA), UMR7364, Strasbourg, France) ;
Wahlund, Lars-Olof (Karolinska Institutet (Estocolm, Suècia). Department of Neurobiology, Care Sciences and Society) ;
Hort, Jakub (International Clinical Research Centre, Brno, Czech Republic) ;
Nedelska, Zuzana (International Clinical Research Centre, Brno, Czech Republic) ;
Padovani, Alessandro (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy) ;
Pilotto, Andrea (Neurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy) ;
Bonanni, Laura (Department of Neuroscience Imaging and Clinical Sciences and CESI, University G d'Annunzio of Chieti-Pescara, Chieti, Italy) ;
Kramberger, Milica G. (Department of Neurology, University Medical Centre Ljubljana, Medical faculty, University of Ljubljana, Ljubljana, Slovenia) ;
Boada, Mercè (Institut Català de Neurociènces Aplicades) ;
Westman, Eric (King's College London) ;
Pagonabarraga Mora, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Kulisevsky, Jaime (Institut d'Investigació Biomèdica Sant Pau) ;
Blanc, Frédéric (Centre National de la Recherche Scientifique (França)) ;
Aarsland, Dag (King's College London. Institute of Psychiatry, Psychology & Neuroscience)
Alzheimer's disease (AD)-related pathology is frequently found in patients with dementia with Lewy bodies (DLB). However, it is unknown how amyloid-β and tau-related pathologies influence neurodegeneration in DLB. [...]
2020 - 10.1016/j.nicl.2020.102333
NeuroImage, Vol. 27 (july 2020)
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5.
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8 p, 1.2 MB |
GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
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Rongve, A. (The University of Bergen) ;
Witoelar, Aree (University of Oslo. Institute of Clinical Medicine) ;
Ruiz, Agustín (Fundació ACE) ;
Athanasiu, Lavinia (University of Oslo) ;
Abdelnour, Carla (Fundació ACE) ;
Clarimón, Jordi (Institut d'Investigació Biomèdica Sant Pau) ;
Heilmann-Heimbach, Stefanie (University of Bonn) ;
Hernández, Isabel (Fundació ACE) ;
Moreno-Grau, Sonia (Fundació ACE) ;
De Rojas, Itziar (Fundació ACE) ;
Morenas-Rodríguez, Estrella (Institut d'Investigació Biomèdica Sant Pau) ;
Fladby, Tormod (University of Oslo) ;
Sando, Sigrid B. (Norwegian University of Science and Technology) ;
Bråthen, Geir (St Olav's University Hospital) ;
Blanc, Frédéric (University of Strasbourg) ;
Bousiges, Olivier (University Hospital of Strasbourg) ;
Lemstra, Afina W. (Amsterdam UMC. University Medical Center) ;
van Steenoven, Inger (Amsterdam UMC. University Medical Center) ;
Londos, Elisabet (Skåne University Hospital (Suècia)) ;
Almdahl, Ina S. (Oslo University Hospital (Oslo, Noruega)) ;
Pålhaugen, Lene (University of Oslo) ;
Eriksen, Jon A. (University of Oslo) ;
Djurovic, Srdjan (University of Bergen) ;
Stordal, Eystein (Norwegian University of Science and Technology) ;
Saltvedt, Ingvild (St Olav's University Hospital) ;
Ulstein, Ingun D. (Oslo University Hospital (Oslo, Noruega)) ;
Bettella, Francesco (Oslo University Hospital (Oslo, Noruega)) ;
Desikan, Rahul S. (Neurology and Pediatrics, UCSF.) ;
Idland, Ane-Victoria (University of Oslo. Institute of Basic Medical Sciences) ;
Toft, Mathias (Oslo University Hospital (Oslo, Noruega)) ;
Pihlstrøm, Lasse (Oslo University Hospital (Oslo, Noruega)) ;
Snaedal, Jon (Landspitali University Hospital (Reykjavík, Islàndia)) ;
Tárraga, Lluís (Fundació ACE) ;
Boada, Mercè (Fundació ACE) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Stefánsson, Hreinn (deCODE Genetics (Reykjavík, Islàndia)) ;
Stefánsson, Kári (deCODE Genetics (Reykjavík, Islàndia)) ;
Ramirez, Alfredo (University of Bonn) ;
Aarsland, Dag (Stavanger University Hospital) ;
Andreassen, Ole A. (University of Oslo) ;
Universitat Autònoma de Barcelona
Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. [...]
2019 - 10.1038/s41598-019-43458-2
Scientific reports, Vol. 9 Núm. 1 (january 2019) , p. 7013
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