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6 p, 557.9 KB |
Interferon-γ-Inducible Protein 10 (IP-10) as a Screening Tool to Optimize Human Immunodeficiency Virus RNA Monitoring in Resource-Limited Settings
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Pastor Palomo, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Casellas, Aina (Institut de Salut Global de Barcelona) ;
Rupérez, María (Centro de Investigação em Saúde da Manhiça) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Maculuve, Sonia (Centro de Investigação em Saúde da Manhiça) ;
Jairoce, Chenjerai (Centro de Investigação em Saúde da Manhiça) ;
Paredes, Roger (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Naniche, Denise (Centro de Investigação em Saúde da Manhiça) ;
Universitat Autònoma de Barcelona
Interferon-γ-inducible protein-10 is an affordable and easily quantifiable biomarker that can be used to accurately screen individuals on antiretroviral treatment (ART) for detectable viremia, optimizing the use of costly viral load determinations required to monitor ART in low-income countries. [...]
2017 -  10.1093/cid/cix600
Clinical Infectious Diseases, Vol. 65 (july 2017) , p. 1670-1675
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2.
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4 p, 721.0 KB |
Detection of SARS-CoV-2 in a cat owned by a COVID-19−affected patient in Spain
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Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Puig, Mariona (Hospital Veterinari Sant Mori S.L) ;
Rodon, Jordi (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Avila-Nieto, Carlos (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Cantero, Guillermo (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Terrón, Maria Teresa (Hospital Veterinari Sant Mori S.L) ;
Cruz, Sílvia (Hospital Veterinari Sant Mori S.L) ;
Parera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Noguera-Julian, Marc (Universitat de Vic - Universitat Central de Catalunya) ;
Izquierdo Useros, Nuria (Institut Germans Trias i Pujol) ;
Guallar, Víctor (Catalan Institution for Research and Advanced Studies) ;
Vidal Barba, Enric (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Valencia, Alfonso (Catalan Institution for Research and Advanced Studies) ;
Blanco, Ignacio (Institut Germans Trias i Pujol) ;
Blanco, Julià (Institut Germans Trias i Pujol) ;
Clotet, Bonaventura (Institut Germans Trias i Pujol) ;
Vergara-Alert, Júlia (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal)
COVID-19 is the most devastating pandemic in recent history. As with many emerging infectious diseases, it is of zoonotic origin, meaning that animals played a major role in the initial transmission events. [...]
2020 - 10.1073/pnas.2010817117
Proceedings of the National Academy of Sciences of the United States of America, Vol. 117 (september 2020) , p. 24790-24793
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3.
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25 p, 3.6 MB |
Methylation regulation of Antiviral host factors, Interferon Stimulated Genes (ISGs) and T-cell responses associated with natural HIV control
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Oriol-Tordera, Bruna (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Berdasco, Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Llano, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Duran-Castells, Clara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ganoza, C. (Alberto Hurtado School of Medicine. Universidad Peruana Cayetano Heredia) ;
Sanchez, J. (Centro de Investigaciones Tecnológicas. Biomédicas y Medioambientales. CITBM) ;
Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Calle, M.L. (Universitat de Vic - Universitat Central de Catalunya) ;
Sánchez-Pla, Àlex (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ruiz Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
GWAS, immune analyses and biomarker screenings have identified host factors associated with in vivo HIV-1 control. However, there is a gap in the knowledge about the mechanisms that regulate the expression of such host factors. [...]
2020 - 10.1371/JOURNAL.PPAT.1008678
PLoS pathogens, Vol. 16 Núm. 8 (june 2020) , p. e1008678
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4.
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12 p, 1.1 MB |
Extremely low viral reservoir in treated chronically HIV-1-infected individuals
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Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Jiménez Valero, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Monceaux, Valérie (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
Huot, Nicolas (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
Leal, Lorna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
González Soler, Victoria (CIBER Epidemiologia y Salud Publica (CIBERESP), Spain) ;
González-Cao, Maria (Translational Cancer Research Unit, Instituto Oncológico Dr Rosell, Dexeus University Hospital, Barcelona, Spain) ;
Müller-Trutwin, Michaela (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
Sáez-Cirión, Asier (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
García, Felipe (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
Small viral reservoirs are found predominantly in HIV-1 controllers and individuals treated during acute/early HIV-1 infection. However, other HIV + individuals could naturally also harbour low viral reservoirs. [...]
2020 - 10.1016/j.ebiom.2020.102830
EBioMedicine, Vol. 57 (june 2020)
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5.
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17 p, 6.0 MB |
Evolution of the gut microbiome following acute HIV-1 infection
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Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rivera Pinto, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Pastor, Lucía (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Guillén Montalbán, Yolanda (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Langhorst, Jost (University of Duisburg-Essen. Chair for Integrative Medicine and translationale Gastroenterology, Klinikum Bamberg) ;
Parera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mandomando, Inacio (Centro de Investigação em Saúde da Manhiça (CISM)) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rodríguez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Calle, Maria Luz (Universitat de Vic - Universitat Central de Catalunya) ;
Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Naniche, Denise (Centro de Investigação em Saúde da Manhiça (CISM)) ;
Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
In rhesus macaques, simian immunodeficiency virus infection is followed by expansion of enteric viruses but has a limited impact on the gut bacteriome. To understand the longitudinal effects of HIV-1 infection on the human gut microbiota, we prospectively followed 49 Mozambican subjects diagnosed with recent HIV-1 infection (RHI) and 54 HIV-1-negative controls for 9-18 months and compared them with 98 chronically HIV-1-infected subjects treated with antiretrovirals (n = 27) or not (n = 71). [...]
2019 - 10.1186/s40168-019-0687-5
Microbiome, Vol. 7 (may 2019)
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6.
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15 p, 3.9 MB |
Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection
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Guillén Montalbán, Yolanda. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Noguera-Julian, Marc (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rivera Pinto, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Casadellà, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Zevin, Alexander (University of Washington) ;
Rocafort, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Parera, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rodríguez, C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Arumí, M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mothe, Beatriz. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Estany Quera, Carla (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Coll, J. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Bravo, I. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Herrero, C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Saz, J. (BCN Checkpoint) ;
Sirera, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Torrella Domingo, Adriana (Hospital Universitari Vall d'Hebron) ;
Navarro Mercadé, Jordi (Hospital Universitari Vall d'Hebron) ;
Crespo, M. (Infectious Diseases Unit. Internal Medicine Department. Complexo Hospitalario Universitario. Vigo. IIS Galicia Sur) ;
Negredo Puigmal, Eugènia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Brander, Christian. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Calle, M.L. (Universitat de Vic - Universitat Central de Catalunya) ;
Klatt, N.R. (University of Washington) ;
Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
Human immunodeficiency virus (HIV)-1 infection causes severe gut and systemic immune damage, but its effects on the gut microbiome remain unclear. Previous shotgun metagenomic studies in HIV-negative subjects linked low-microbial gene counts (LGC) to gut dysbiosis in diseases featuring intestinal inflammation. [...]
2019 - 10.1038/s41385-018-0083-7
Mucosal Immunology, Vol. 12 Núm. 1 (january 2019) , p. 232-246
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7.
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15 p, 1.8 MB |
Different pattern of stool and plasma gastrointestinal damage biomarkers during primary and chronic HIV infection
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Pastor Palomo, Lucía (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Langhorst, J. (Department of Internal and Integrative Medicine. Kliniken Essen-Mitte. Faculty of Medicine. University of Duisburg-Essen) ;
Schröder, D. (Department of Internal and Integrative Medicine. Kliniken Essen-Mitte. Faculty of Medicine. University of Duisburg-Essen) ;
Casellas, A. (Barcelona Institute for Global Health (ISGlobal)) ;
Ruffer, A. (Department of Internal and Integrative Medicine. Kliniken Essen-Mitte. Faculty of Medicine. University of Duisburg-Essen) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Massora, S. (Centro de Investigação em Saúde da Manhiça (CISM)) ;
Mandomando, I. (Centro de Investigação em Saúde da Manhiça (CISM)) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Naniche, D. (Centro de Investigação em Saúde da Manhiça (CISM)) ;
Universitat Autònoma de Barcelona
Introduction Primary HIV infection (PHI) is the initial phase after HIV acquisition characterized by high viral replication, massive inflammatory response and irreversible immune-damage, particularly at the gastrointestinal level. [...]
2019 - 10.1371/journal.pone.0218000
PloS one, Vol. 14 Núm. 6 (june 2019) , p. e0218000
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8.
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12 p, 347.3 KB |
Myalgic encephalomyelitis/chronic fatigue Syndrome (ME/CFS) : Investigating care practices pointed out to disparities in diagnosis and treatment across European Union
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Strand, E.B. (Oslo University Hospital HF. CFS/ME Centre. Norwegian National Advisory Unit on CFS/ME) ;
Nacul, L. (Faculty of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine) ;
Mengshoel, A.M. (Department of Health Sciences. Institute of Health and Society. University of Oslo) ;
Helland, I.B. (Oslo University Hospital Rikshospitalet) ;
Grabowski, P. (Institute for Medical Immunology. Charité-Universitätsmedizin Berlin) ;
Krumina, A. (Riga Stradins University) ;
Alegre Martín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Efrim-Budisteanu, M. (Research Psychiatry Laboratory. "Alexandru Obregia" Clinical Hospital of Psychiatry) ;
Sekulic, S. (Medical Faculty Novi Sad) ;
Pheby, D. (University College London. Rayne Institute) ;
Sakkas, G.K. (Live Laboratory. School of PE and Sport Sciences. University of Thessaly) ;
Sirbu, C.A. (Central Military Emergency Hospital. Carol Davila) ;
Authier, F.J. (Lorraine University. Nancy University hospital. CHU de Nancy. Hôpitaux de Brabois) ;
Murovska, M. (Riga Stradins University) ;
Lacerda, E. (Faculty of Infectious and Tropical Diseases. London School of Hygiene and Tropical Medicine) ;
Estevez Lopez, F. (CVS/ME Medisch Centrum) ;
Scheibenbogen, C. (University Hospital Erlangen. Department of Medicine 3) ;
Shi-Kova-Lekova, E. (National Center of Infectious and Parasitic Diseases) ;
Lorusso, L. (University of Pavia) ;
Berkis, U. (Riga Stradins University) ;
Westermeier, F. (FH Joanneum) ;
Riederer, M. (FH Joanneum) ;
Tobback, E. (University Hospital Ghent) ;
Meeus, M. (Universiteit Antwerpen. Campus Drie Eiken) ;
Shikova-Lekova, E. ;
Nielsen, H. (PrivatHospitalet Danmark) ;
Brandslund, I. (Lillebaelt Hospital) ;
Polo, O. (Unesta Research Center) ;
De Korwin, J.D. (Lorraine University. Nancy University hospital. CHU de Nancy. Hôpitaux de Brabois) ;
Scheibenbogen, C. (University Hospital Erlangen. Department of Medicine 3) ;
Harrer, T. (University Hospital Erlangen. Department of Medicine 3) ;
Prusty, B. (Julius Maximilian University of Wuerzburg. Department of Microbiology. University of Wuerzburg Biozentrum) ;
Freitag, H. (Institute for Medical Immunology. Charité-Universitätsmedizin Berlin) ;
Trepel, D. (Trinity College Dublin. Trinity College. Office 0.81. Lloyd Building) ;
Cullinan, J. (NUI Galway Discipline of Economics. NUI Galway) ;
Lorusso, L. (University of Pavia) ;
Capelli, E. (University of Pavia) ;
Nora-Krukle, Z. (Institute for Medical Immunology. Charité-Universitätsmedizin Berlin) ;
Rasa, S. (Institute for Medical Immunology. Charité-Universitätsmedizin Berlin) ;
Vermeulen, R. (CVS/ME Medisch Centrum) ;
Menhshoel, A.M. (University of Oslo) ;
Helland, I.B. (Oslo University Hospital Rikshospitalet) ;
Zalewski, P. (Nicolaus Copernicus University in Torun Collegium Medicum) ;
Sepulveda, N. (Centre of Statistics and Application. University of Lisbon. Faculdade de Ciencias) ;
Sirbu, C.A. (Central Military Emergency Hospital. Carol Davila) ;
Sekulic, S. (Medical Faculty Novi Sad) ;
Vukadinovic, M. (Novi Sad Business School) ;
Marusic, U. (Science and research centre Koper) ;
Pisot, R. ;
Castro-Marrero, Jesús. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Blanco, Julià (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Oltra, E. (Universidad Catolica de Valencia) ;
Miro, J. (Universitat Rovira i Virgili. Departament de Psicologia) ;
Berquist, J. (Uppsala University Analytical Chemistry) ;
Blomberg, J. (Uppsala University. Medical Sciences. Academic Hospital) ;
Pheby, D. (University College London. Rayne Institute) ;
Edwards, J. (University College London. Rayne Institute) ;
Wang, X. (School of Pharmacy. Norwich Medical School. Faculty of Medicine and Health Sciences. University of East Anglia) ;
Universitat Autònoma de Barcelona
ME/CFS is a chronic, complex, multisystem disease that often limits the health and functioning of the affected patients. Diagnosing patients with ME/CFS is a challenge, and many different case definitions exist and are used in clinical practice and research. [...]
2019 - 10.1371/journal.pone.0225995
PloS one, Vol. 14 Núm. 12 (january 2019) , p. e0225995
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9.
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Methodological framework for the implementation of circular economy in urban systems
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Sánchez Levoso, Ana (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ;
Martínez Gasol, Carles (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ;
Martínez Blanco, Julia (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ;
Gabarrell Durany, Xavier (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals) ;
Lehmann, Martin (Aalborg University. Department of Planning) ;
Farreny Gaya, Ramon (Universitat Autònoma de Barcelona. Institut de Ciència i Tecnologia Ambientals)
Urban areas are hubs for innovation, economic activity and growth that hugely influence the development of our society, making those areas important drivers in the global transition towards circular economy. [...]
2020 - 10.1016/j.jclepro.2019.119227
Journal of cleaner production, Vol. 248 (March 2020) , art. 119227
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10.
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9 p, 1.7 MB |
Switching From a Protease Inhibitor-based Regimen to a Dolutegravir-based Regimen : A Randomized Clinical Trial to Determine the Effect on Peripheral Blood and Ileum Biopsies From Antiretroviral Therapy-suppressed Human Immunodeficiency Virus-infected Individuals
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Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Navarro, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Jimenez, Montse (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rutsaert, Sofie (Human Immunodeficiency Virus Cure Research Center, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University and Ghent University Hospital) ;
Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Puertas, Maria C (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Torrella, Ariadna (Hospital Universitari Vall d'Hebron) ;
De Clercq, Laura (Human Immunodeficiency Virus Cure Research Center, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University and Ghent University Hospital) ;
Ribas, Bibiana Planas (Hospital Universitari Vall d'Hebron) ;
Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Vandekerckhove, Linos (Human Immunodeficiency Virus Cure Research Center, Department of Internal Medicine, Faculty of Medicine and Health Sciences, Ghent University and Ghent University Hospital) ;
Blanco, Julià (Universitat de Vic - Universitat Central de Catalunya) ;
Crespo, Manel (Infectious Diseases Unit, Internal Medicine Department, Complexo Hospitalario Universitario de Vigo, Instituto de Investigación Sanitaria Galicia Sur) ;
Martinez-Picado, Javier (Catalan Institution for Research and Advanced Studies) ;
Universitat Autònoma de Barcelona
Optimization of combination antiretroviral therapy (cART) can impact the human immunodeficiency virus (HIV) reservoir. We evaluated the effect on the HIV reservoir in peripheral blood and ileum biopsies in patients switching from boosted protease inhibitor (PI/r)-based therapy to dolutegravir (DTG)-based therapy. [...]
2018 - 10.1093/cid/ciy1095
Clinical Infectious Diseases, Vol. 69 (december 2018) , p. 1320-1328
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