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Articles 1 registres trobats  
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8 p, 1.0 MB Direct interaction between a human digestive protease and the mucoadhesive poly(acrylic acid) / Pallarès i Goitiz, Irantzu (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Fernández Fleischhauer, Daniel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Comellas-Bigler, Mireia (Max-Planck Institute of Biochemistry. Proteinase Research Group) ; Fernández-Recio, Juan (Barcelona Supercomputing Center) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Avilés, Francesc X. (Francesc Xavier) (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Bode, Wolfram (Max-Planck Institute of Biochemistry. Proteinase Research Group) ; Vendrell i Roca, Josep (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Carboxypeptidase A1 has been the subject of extensive research in the last 30 y and is one of the most widely studied zinc metalloenzymes. However, the three-dimensional structure of the human form of the enzyme is not yet available. [...]
2008 - 10.1107/S0907444908013474
Acta crystallographica. Section D, Biological crystallography, Vol. 64, Issue 7 (July 2008) , p. 784-791  

Documents de recerca 1 registres trobats  
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22 p, 292.4 KB Crystal structure of human granzyme B : Modelling of the granzyme B-Cation-Independent Mannose-6-Phosphate Receptor Complex ; Crystal structure of Human Pro-Granzyme K ; Crystal structure of the Procarboxypeptidase from Helicoverpa armigera / Estébanez Perpiñá, Eva ; Huber, Robert, dir. (Max Planck Institut für Biochemie) ; Bode, Wolfram, dir.
Estructura Tridimensional de Granzima B humana Granzima B es la proteina prototípica de la familia de serina proteasas que se encuentran en células NK y CTLs. GzmB induce apoptosis mediante activación de las caspasas, y está implicada en la etiología de la artritis reumatoidea. [...]
Crystal Structure of Human Granzyme B Granzyme B is the prototypic member of the granzymes, trypsin-like serine proteinases localized in activated NK cells and CTLs. GzmB triggers apoptosis by activating the caspases, and is implicated in the etiology of rheumatoid arthritis. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2003
4 documents

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1 Bode, Wolfram,
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