Home > Search Results: Borthwick, Nicola
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Articles, 3 records found
Articles 3 records found  
1.
19 p, 1.4 MB Novel, in-natural-infection subdominant HIV-1 CD8 + T-cell epitopes revealed in human recipients of conserved-region T-cell vaccines / Borthwick, Nicola (The Jenner Institute, University of Oxford) ; Lin, Zhansong (Kumamoto University, Japan) ; Akahoshi, Tomohiro (Kumamoto University, Japan) ; Llano Montero, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Silva-Arrieta, Sandra (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ahmed, Tina (University of Oxford) ; Dorrell, Lucy (University of Oxford) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Murakoshi, Hayato (Kumamoto University, Japan) ; Takiguchi, Masafumi (Kumamoto University, Japan) ; Hanke, Tomáš (University of Oxford)
Fine definition of targeted CD8 + T-cell epitopes and their human leucocyte antigen (HLA) class I restriction informs iterative improvements of HIV-1 T-cell vaccine designs and may predict early vaccine success or failure. [...]
2017 - 10.1371/journal.pone.0176418
PloS one, Vol. 12 (april 2017)  
Detailed record - Creative Commons
2.
16 p, 2.9 MB Therapeutic Vaccination Refocuses T-cell Responses Towards Conserved Regions of HIV-1 in Early Treated Individuals (BCN 01 study) / Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Manzardo, Christian (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Sánchez-Bernabeu, Álvaro (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Coll, Pep (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rosás-Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cobarsi, Patricia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Escrig, Roser (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ruiz, Irene (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rovira, Cristina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Meulbroek, Michael (Projecte del Noms, BCN Checkpoint, Barcelona, Spain) ; Crook, Alison (The Jenner Institute, University of Oxford, Oxford, UK) ; Borthwick, Nicola (The Jenner Institute, University of Oxford, Oxford, UK) ; Wee, Edmund G. (The Jenner Institute, University of Oxford, Oxford, UK) ; Yang, Hongbing (University of Oxford. Nuffield Department of Medicine) ; Miró, José M (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Dorrell, Lucy (University of Oxford. Nuffield Department of Medicine) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hanke, Tomáš (International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan) ; Universitat Autònoma de Barcelona
Strong and broad antiviral T-cell responses targeting vulnerable sites of HIV-1 will likely be a critical component for any effective cure strategy. BCN01 trial was a phase I, open-label, non-randomized, multicenter study in HIV-1-positive individuals diagnosed and treated during early HIV-1 infection to evaluate two vaccination regimen arms, which differed in the time (8 versus 24 week) between the ChAdV63. [...]
2019 - 10.1016/j.eclinm.2019.05.009
EClinicalMedicine, Vol. 11 (june 2019) , p. 65-80  
Detailed record - Creative Commons
3.
1 p, 240.0 KB Corrigendum to 'Therapeutic vaccination refocuses T-cell responses towards conserved regions of HIV-1 in early treated individuals (BCN 01 study)' EClinicalMedicine 11 (2019) 65-80 / Mothe, Beatriz (Universitat de Vic - Universitat Central de Catalunya) ; Manzardo, Christian (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Sanchez-Bernabeu, Alvaro (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Coll, Pep (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Moron-Lopez, Sara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rosás-Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Cobarsi, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Escrig, Roser (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ruiz, Irene (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rovira, Cristina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Meulbroek, Michael (Projecte del Noms, BCN Checkpoint, Barcelona, Spain) ; Crook, Alison (The Jenner Institute, University of Oxford, Oxford, UK) ; Borthwick, Nicola (The Jenner Institute, University of Oxford, Oxford, UK) ; Wee, Edmund G. (The Jenner Institute, University of Oxford, Oxford, UK) ; Yang, Hongbing (University of Oxford. Nuffield Department of Medicine) ; Miró, José M (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Dorrell, Lucy (University of Oxford. Nuffield Department of Medicine) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Hanke, Tomáš (International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan) ; Universitat Autònoma de Barcelona
2020 - 10.1016/j.eclinm.2019.100250
EClinicalMedicine, Vol. 18 (january 2020)  
Detailed record - Creative Commons

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1 Borthwick, N.
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